NO152047C - Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin

Info

Publication number
NO152047C
NO152047C NO800447A NO800447A NO152047C NO 152047 C NO152047 C NO 152047C NO 800447 A NO800447 A NO 800447A NO 800447 A NO800447 A NO 800447A NO 152047 C NO152047 C NO 152047C
Authority
NO
Norway
Prior art keywords
paradeuterophenyl
preparation
therapeutic activity
deuterated
linear
Prior art date
Application number
NO800447A
Other languages
English (en)
Other versions
NO800447L (no
NO152047B (no
Inventor
Pierre Dumont
Jacques Poupaert
Original Assignee
Wallone Region
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallone Region filed Critical Wallone Region
Publication of NO800447L publication Critical patent/NO800447L/no
Publication of NO152047B publication Critical patent/NO152047B/no
Publication of NO152047C publication Critical patent/NO152047C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
NO800447A 1979-02-20 1980-02-19 Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin NO152047C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7904209A FR2449448B1 (fr) 1979-02-20 1979-02-20 Composition pharmaceutique comprenant un derive de phenylhydantoine, derives mis en oeuvre et leur preparation

Publications (3)

Publication Number Publication Date
NO800447L NO800447L (no) 1980-08-21
NO152047B NO152047B (no) 1985-04-15
NO152047C true NO152047C (no) 1985-07-24

Family

ID=9222166

Family Applications (1)

Application Number Title Priority Date Filing Date
NO800447A NO152047C (no) 1979-02-20 1980-02-19 Analogifremgangsmaate for fremstilling av terapeutisk virksom 5-(paradeuterofenyl)-5-fenylhydantoin

Country Status (11)

Country Link
US (1) US4304782A (no)
EP (1) EP0015038B1 (no)
JP (1) JPS55133362A (no)
AT (1) ATE10804T1 (no)
CA (1) CA1139672A (no)
DE (1) DE3069813D1 (no)
DK (1) DK71780A (no)
ES (1) ES488788A0 (no)
FI (1) FI71556C (no)
FR (1) FR2449448B1 (no)
NO (1) NO152047C (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07106837B2 (ja) * 1989-01-31 1995-11-15 シャープ株式会社 シート状体の循環式供給装置
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
USRE35956E (en) * 1991-01-09 1998-11-10 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
JPH04297461A (ja) * 1991-03-27 1992-10-21 Otsuka Pharmaceut Factory Inc ２−チオヒダントイン誘導体
US6334997B1 (en) * 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
AU707748B2 (en) * 1994-03-25 1999-07-22 Isotechnika Inc. Enhancement of the efficacy of drugs by deuteration
AU1917899A (en) * 1998-03-20 1999-10-18 Warner-Lambert Company Crystalline sodium phenytoin monohydrate
US6063934A (en) * 1998-03-25 2000-05-16 Bristol-Myers Squibb Company Imidazolone anorectic agents: 1. 2-substituted-3,5-dihydro-5,5-diphenyl-4H-imidazol-4-ones
DE10214228A1 (de) * 2002-03-22 2003-10-02 Bdd Group Holding Ag Zug Deuterierte substitutierte Indole sowie diese Verbindungen enthaltende Arzneimittel
JP2007514442A (ja) * 2003-12-19 2007-06-07 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 前立腺癌治療を評価するための方法および物質
US7718684B2 (en) * 2004-02-24 2010-05-18 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
US7709517B2 (en) * 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
PL2368550T3 (pl) 2006-03-27 2014-01-31 Univ California Modulator receptorów androgenowych do leczenia raka gruczołu krokowego i chorób związanych z receptorami androgenów
EP2439196A1 (en) 2006-03-29 2012-04-11 The Regents of The University of California Diarylthiohydantoin compounds for use in a method for the treatment of a hyperproliferative disorder
CA2966280A1 (en) 2007-10-26 2009-04-30 The Regents Of The University Of California Diarylhydantoin compounds
EP3124481B1 (en) 2010-02-16 2018-03-28 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and uses thereof
CA2885415C (en) 2012-09-26 2021-06-29 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
EP3697398A1 (en) 2017-10-16 2020-08-26 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer

Also Published As

Publication number Publication date
JPS55133362A (en) 1980-10-17
FI71556C (fi) 1987-01-19
DK71780A (da) 1980-08-21
FI71556B (fi) 1986-10-10
FI800502A (fi) 1980-08-21
ES8200011A1 (es) 1981-10-16
DE3069813D1 (en) 1985-01-31
EP0015038A1 (fr) 1980-09-03
CA1139672A (en) 1983-01-18
EP0015038B1 (fr) 1984-12-19
NO800447L (no) 1980-08-21
ATE10804T1 (de) 1985-01-15
FR2449448B1 (fr) 1983-05-27
ES488788A0 (es) 1981-10-16
NO152047B (no) 1985-04-15
FR2449448A1 (fr) 1980-09-19
US4304782A (en) 1981-12-08

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