IT1049373B - Fluoro prostaglandine - Google Patents

Fluoro prostaglandine

Info

Publication number
IT1049373B
IT1049373B IT21493/75A IT2149375A IT1049373B IT 1049373 B IT1049373 B IT 1049373B IT 21493/75 A IT21493/75 A IT 21493/75A IT 2149375 A IT2149375 A IT 2149375A IT 1049373 B IT1049373 B IT 1049373B
Authority
IT
Italy
Prior art keywords
prostaglandine
fluorine
prostaglandine fluorine
Prior art date
Application number
IT21493/75A
Other languages
English (en)
Inventor
R Pellegata
C Gandolfi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Priority to IT21493/75A priority Critical patent/IT1049373B/it
Priority to AU11917/76A priority patent/AU501803B2/en
Priority to IL49208A priority patent/IL49208A/xx
Priority to ZA761611A priority patent/ZA761611B/xx
Priority to DK116676A priority patent/DK146593C/da
Priority to CS761740A priority patent/CS191296B2/cs
Priority to CY956A priority patent/CY956A/xx
Priority to GB10988/76A priority patent/GB1493557A/en
Priority to NL7602862A priority patent/NL7602862A/xx
Priority to FR7608070A priority patent/FR2313029A1/fr
Priority to BE165354A priority patent/BE839789A/xx
Priority to CH349276A priority patent/CH629769A5/de
Priority to HU76EA158A priority patent/HU175729B/hu
Priority to SU762336447A priority patent/SU710516A3/ru
Priority to SE7603431A priority patent/SE427109B/xx
Priority to DE2611788A priority patent/DE2611788C2/de
Priority to CA248,218A priority patent/CA1103663A/en
Priority to AT204576A priority patent/AT351189B/de
Priority to JP51031179A priority patent/JPS5921864B2/ja
Priority to KE2859A priority patent/KE2859A/xx
Priority to HK449/78A priority patent/HK44978A/xx
Priority to US05/944,614 priority patent/US4338332A/en
Priority to MY358/78A priority patent/MY7800358A/xx
Priority to US06/009,098 priority patent/US4320143A/en
Priority to US06/034,188 priority patent/US4229585A/en
Priority to SE7908642A priority patent/SE431090B/sv
Priority to DK7480A priority patent/DK146652C/da
Priority to US06/137,233 priority patent/US4338249A/en
Priority to CH317880A priority patent/CH623570A5/de
Application granted granted Critical
Publication of IT1049373B publication Critical patent/IT1049373B/it
Priority to DK92381A priority patent/DK146938C/da
Priority to US06/302,079 priority patent/US4425359A/en
Priority to JP59005843A priority patent/JPS6033826B2/ja

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/12—1,4-Dioxanes; Hydrogenated 1,4-dioxanes not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT21493/75A 1975-03-12 1975-03-21 Fluoro prostaglandine IT1049373B (it)

Priority Applications (32)

Application Number Priority Date Filing Date Title
IT21493/75A IT1049373B (it) 1975-03-21 1975-03-21 Fluoro prostaglandine
AU11917/76A AU501803B2 (en) 1975-03-21 1976-03-12 Fluoro-prostaglandins
IL49208A IL49208A (en) 1975-03-21 1976-03-12 13,14-dehydro-16-fluoro prostanoic acid derivatives of the f2,a2 and e2 series,process for their preparation and pharmaceutical compositions containing same
ZA761611A ZA761611B (en) 1975-03-21 1976-03-16 Fluooro-prostaglandins and process for their preparation
DK116676A DK146593C (da) 1975-03-21 1976-03-17 Analogifremgangsmaade til fremstilling af fluorprostaglandiner
CS761740A CS191296B2 (en) 1975-03-21 1976-03-17 Process for preparing optically active or racemic fluorprostaglandine
GB10988/76A GB1493557A (en) 1975-03-21 1976-03-18 Fluoro-prostaglandins and process for their preparation
NL7602862A NL7602862A (nl) 1975-03-21 1976-03-18 Fluorprostaglandinen en werkwijze ter bereiding ervan.
CY956A CY956A (en) 1975-03-21 1976-03-18 Fluoro-prostaglandins and process for their preparation
SE7603431A SE427109B (sv) 1975-03-21 1976-03-19 Forfarande for framstellning av 16-fluorsubstituerade prostaglandinderivat
BE165354A BE839789A (fr) 1975-03-21 1976-03-19 Prostaglandines fluorees, leur preparation et leur utilisation, entre autres comme substances luteolytiques
CH349276A CH629769A5 (de) 1975-03-21 1976-03-19 Verfahren zur herstellung von fluorprostaglandinen.
HU76EA158A HU175729B (hu) 1975-03-21 1976-03-19 Sposob poluchenija ftoroprostaglandinov
SU762336447A SU710516A3 (ru) 1975-03-21 1976-03-19 Способ получени оптически активных производных фторпростагландинов или их рацематов
FR7608070A FR2313029A1 (fr) 1975-03-21 1976-03-19 Fluoroprostaglandines, procede permettant leur preparation, et leur utilisation therapeutique
DE2611788A DE2611788C2 (de) 1975-03-21 1976-03-19 Fluorprostaglandine, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel
CA248,218A CA1103663A (en) 1975-03-21 1976-03-19 Fluoro-prostaglandins and process for their preparation
AT204576A AT351189B (de) 1975-03-21 1976-03-19 Verfahren zur herstellung von neuen fluor- prostaglandinen
JP51031179A JPS5921864B2 (ja) 1975-03-21 1976-03-22 フルオロプロスタグランジン及びその製造法
KE2859A KE2859A (en) 1975-03-21 1978-06-18 Fluoro-prostaglandins and process for their preparation
HK449/78A HK44978A (en) 1975-03-21 1978-08-10 Fluoro-prostaglandins and process for their preparation
US05/944,614 US4338332A (en) 1975-03-21 1978-09-21 Fluoro-prostaglandins
MY358/78A MY7800358A (en) 1975-03-21 1978-12-30 Fluoro-prostalaglandins and process for their preparation
US06/009,098 US4320143A (en) 1975-03-21 1979-02-02 Fluoro-prostaglandins and process for their preparation
US06/034,188 US4229585A (en) 1975-03-21 1979-04-27 Fluoro-prostaglandins
SE7908642A SE431090B (sv) 1975-03-21 1979-10-18 Optiskt aktiv eller racemisk fluor-prostaglandinforening till anvendning som luteolytiskt och abortivt medel
DK7480A DK146652C (da) 1975-03-21 1980-01-07 Optisk aktive eller racemiske 16-fluor-prostaglandiner til anvendelse som abortfremkaldende midler
US06/137,233 US4338249A (en) 1975-03-21 1980-04-07 Cyclopenta[b]furan-2-one and -2-ol intermediates for 16-fluoro-13,14-didehydro-prostaglandins
CH317880A CH623570A5 (it) 1975-03-21 1980-04-24
DK92381A DK146938C (da) 1975-03-21 1981-02-27 Analogifremgangsmaade til fremstilling af fluor-prostaglandiner
US06/302,079 US4425359A (en) 1975-03-12 1981-08-14 Fluoro-prostaglandins and process for their preparation
JP59005843A JPS6033826B2 (ja) 1975-03-21 1984-01-18 フルオロプロスタグランジン及びその製造法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21493/75A IT1049373B (it) 1975-03-21 1975-03-21 Fluoro prostaglandine

Publications (1)

Publication Number Publication Date
IT1049373B true IT1049373B (it) 1981-01-20

Family

ID=11182621

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21493/75A IT1049373B (it) 1975-03-12 1975-03-21 Fluoro prostaglandine

Country Status (13)

Country Link
JP (2) JPS5921864B2 (it)
CS (1) CS191296B2 (it)
CY (1) CY956A (it)
DK (1) DK146593C (it)
HK (1) HK44978A (it)
HU (1) HU175729B (it)
IL (1) IL49208A (it)
IT (1) IT1049373B (it)
KE (1) KE2859A (it)
MY (1) MY7800358A (it)
SE (2) SE427109B (it)
SU (1) SU710516A3 (it)
ZA (1) ZA761611B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3469736D1 (de) * 1983-09-07 1988-04-14 Indiana University Foundation 12, 16-difluoroprostaglandin f2 alpha compounds
JPS60229814A (ja) * 1984-04-27 1985-11-15 Iseki & Co Ltd 小型車輛における車輪の上下装置
JPS62196619U (it) * 1986-06-02 1987-12-14
EP0591532A4 (en) * 1991-04-22 1994-11-09 Taisho Pharmaceutical Co Ltd PROSTAGLANDIN E1 ANALOG.

Also Published As

Publication number Publication date
SE7603431L (sv) 1976-09-22
IL49208A (en) 1980-10-26
DK116676A (da) 1976-09-22
CY956A (en) 1978-12-22
MY7800358A (en) 1978-12-31
SE427109B (sv) 1983-03-07
IL49208A0 (en) 1976-05-31
JPS5921864B2 (ja) 1984-05-22
SE431090B (sv) 1984-01-16
JPS51118747A (en) 1976-10-18
SE7908642L (sv) 1979-10-18
JPS59144753A (ja) 1984-08-18
HK44978A (en) 1978-08-18
HU175729B (hu) 1980-10-28
DK146593C (da) 1984-04-30
SU710516A3 (ru) 1980-01-15
KE2859A (en) 1978-08-04
JPS6033826B2 (ja) 1985-08-05
ZA761611B (en) 1977-03-30
DK146593B (da) 1983-11-14
CS191296B2 (en) 1979-06-29

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