DE3469736D1 - 12, 16-difluoroprostaglandin f2 alpha compounds - Google Patents

12, 16-difluoroprostaglandin f2 alpha compounds

Info

Publication number
DE3469736D1
DE3469736D1 DE8484110602T DE3469736T DE3469736D1 DE 3469736 D1 DE3469736 D1 DE 3469736D1 DE 8484110602 T DE8484110602 T DE 8484110602T DE 3469736 T DE3469736 T DE 3469736T DE 3469736 D1 DE3469736 D1 DE 3469736D1
Authority
DE
Germany
Prior art keywords
difluoroprostaglandin
alpha compounds
alpha
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484110602T
Other languages
English (en)
Inventor
Paul A Dr Grieco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indiana University Foundation
Original Assignee
Indiana University Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indiana University Foundation filed Critical Indiana University Foundation
Application granted granted Critical
Publication of DE3469736D1 publication Critical patent/DE3469736D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8484110602T 1983-09-07 1984-09-06 12, 16-difluoroprostaglandin f2 alpha compounds Expired DE3469736D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53009783A 1983-09-07 1983-09-07

Publications (1)

Publication Number Publication Date
DE3469736D1 true DE3469736D1 (de) 1988-04-14

Family

ID=24112437

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484110602T Expired DE3469736D1 (de) 1983-09-07 1984-09-06 12, 16-difluoroprostaglandin f2 alpha compounds

Country Status (4)

Country Link
EP (1) EP0136589B1 (de)
JP (1) JPS6072860A (de)
CA (1) CA1253494A (de)
DE (1) DE3469736D1 (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1396207A (en) * 1972-04-27 1975-06-04 Upjohn Co Prostaglandin intermediates and the preparation thereof
IT1049373B (it) * 1975-03-21 1981-01-20 Erba Carlo Spa Fluoro prostaglandine
US4284794A (en) * 1976-12-16 1981-08-18 University Of Pittsburgh Prostaglandin derivatives

Also Published As

Publication number Publication date
EP0136589B1 (de) 1988-03-09
EP0136589A3 (en) 1985-08-28
CA1253494A (en) 1989-05-02
JPS6072860A (ja) 1985-04-24
EP0136589A2 (de) 1985-04-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee