SE7412140L - - Google Patents
Info
- Publication number
- SE7412140L SE7412140L SE7412140A SE7412140A SE7412140L SE 7412140 L SE7412140 L SE 7412140L SE 7412140 A SE7412140 A SE 7412140A SE 7412140 A SE7412140 A SE 7412140A SE 7412140 L SE7412140 L SE 7412140L
- Authority
- SE
- Sweden
- Prior art keywords
- nle
- ile
- phe
- leu
- ser
- Prior art date
Links
- AGPKZVBTJJNPAG-RFZPGFLSSA-N D-Isoleucine Chemical group CC[C@@H](C)[C@@H](N)C(O)=O AGPKZVBTJJNPAG-RFZPGFLSSA-N 0.000 abstract 1
- -1 D-Phg Chemical compound 0.000 abstract 1
- MTCFGRXMJLQNBG-UWTATZPHSA-N D-Serine Chemical compound OC[C@@H](N)C(O)=O MTCFGRXMJLQNBG-UWTATZPHSA-N 0.000 abstract 1
- 125000003301 D-leucyl group Chemical group N[C@@H](C(=O)*)CC(C)C 0.000 abstract 1
- FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 abstract 1
- COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-STHAYSLISA-N D-threonine Chemical compound C[C@H](O)[C@@H](N)C(O)=O AYFVYJQAPQTCCC-STHAYSLISA-N 0.000 abstract 1
- KZSNJWFQEVHDMF-SCSAIBSYSA-N D-valine Chemical compound CC(C)[C@@H](N)C(O)=O KZSNJWFQEVHDMF-SCSAIBSYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000016087 ovulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10995173A JPS5314072B2 (fr) | 1973-09-29 | 1973-09-29 | |
JP2744274A JPS5726506B2 (fr) | 1974-03-08 | 1974-03-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7412140L true SE7412140L (fr) | 1975-04-01 |
SE420717B SE420717B (sv) | 1981-10-26 |
Family
ID=26365357
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7412140A SE420717B (sv) | 1973-09-29 | 1974-09-26 | Sett att framstella nya nonapeptidamidderivat med ovulationsinducerande aktivitet |
Country Status (17)
Country | Link |
---|---|
US (1) | US4008209A (fr) |
AT (1) | AT347054B (fr) |
BE (1) | BE820451A (fr) |
CA (1) | CA1027114A (fr) |
CH (1) | CH603559A5 (fr) |
CS (1) | CS180644B2 (fr) |
DE (1) | DE2446005C2 (fr) |
DK (1) | DK148305C (fr) |
ES (1) | ES430495A1 (fr) |
FI (1) | FI61028C (fr) |
FR (1) | FR2245375B1 (fr) |
GB (1) | GB1434694A (fr) |
HK (1) | HK15579A (fr) |
HU (1) | HU173783B (fr) |
NL (3) | NL179289C (fr) |
NO (2) | NO143218C (fr) |
SE (1) | SE420717B (fr) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2735515A1 (de) * | 1977-08-06 | 1979-02-22 | Hoechst Ag | Verwendung von lh-rh-peptiden als antikonzeptive |
FR2450109B1 (fr) * | 1977-11-08 | 1986-03-28 | Roussel Uclaf | Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes |
US4215038A (en) * | 1978-10-16 | 1980-07-29 | The Salk Institute For Biological Studies | Peptides which inhibit gonadal function |
US4359312A (en) * | 1978-08-15 | 1982-11-16 | Zumtobel Kg | Reciprocating pump for the pulsation-free delivery of a liquid |
US4256737A (en) * | 1979-06-11 | 1981-03-17 | Syntex (U.S.A.) Inc. | Long acting depot injectable formulations for LH-RH analogues |
DE3020941A1 (de) * | 1980-06-03 | 1981-12-17 | Hoechst Ag, 6000 Frankfurt | Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung |
ZA815447B (en) * | 1980-08-29 | 1982-08-25 | Salk Inst For Biological Studi | Peptides affecting gonadal function |
US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
CS230614B1 (en) * | 1982-08-06 | 1984-08-13 | Martin Cs Flegel | Analogues of realising factor for luteining and folliculstimulated hormon |
US4491541A (en) * | 1982-11-10 | 1985-01-01 | Farmitalia Carlo Erba | Peptides |
IT1178775B (it) * | 1983-12-23 | 1987-09-16 | Konzponti Valto Es Hitelbank R | Derivati della gonadoliberina e procedimento per la loro preparazione |
HU189394B (en) * | 1983-12-23 | 1986-06-30 | Koezponti Valto- Es Hitelbank Rt Innovacios Alap,Hu | Method for producing spermatozoa suitable for fertilization from mature fishes |
DE3411224A1 (de) * | 1984-03-27 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren |
HU193093B (en) * | 1985-04-16 | 1987-08-28 | Innofinance | Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation |
HU193607B (en) * | 1985-07-18 | 1987-11-30 | Innofinance Altalanos Innovaci | Process for production of sexual products applyable for natural or artificial insemination for mammates |
US4762717A (en) * | 1986-03-21 | 1988-08-09 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive |
US4897268A (en) * | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
US5068221A (en) * | 1989-05-09 | 1991-11-26 | Mathias John R | Treatment of motility disorders with a gnrh analog |
JP2653255B2 (ja) | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
CA2050425A1 (fr) | 1990-09-03 | 1992-03-04 | Yoshiaki Uda | Composition pharmaceutique et son utilisation avec du mucus |
ZA918168B (en) | 1990-10-16 | 1993-04-14 | Takeda Chemical Industries Ltd | Prolonged release preparation and polymers thereof. |
US5434136A (en) * | 1990-12-14 | 1995-07-18 | Mathias; John R. | Treatment of motility disorders with a GNRH analog |
US5518730A (en) * | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
DK0582459T3 (da) | 1992-08-07 | 1998-04-27 | Takeda Chemical Industries Ltd | Fremstilling af mikrokapsler af vandopløselige lægemidler |
EP1138345A3 (fr) | 1993-09-22 | 2003-06-04 | Hisamitsu Pharmaceutical Co., Inc. | Une matrice pour l' iontophorèse |
US5594091A (en) * | 1994-02-21 | 1997-01-14 | Takeda Chemical Industries, Ltd. | Matrix for sustained-release preparation |
US6117455A (en) * | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
IL115099A (en) | 1994-10-14 | 1999-04-11 | Upjohn Co | Lyophilizate of phospholipid complex of water insoluble camptothecins |
US5837281A (en) | 1995-03-17 | 1998-11-17 | Takeda Chemical Industries, Ltd. | Stabilized interface for iontophoresis |
CA2192773C (fr) | 1995-12-15 | 2008-09-23 | Hiroaki Okada | Obtention d'une preparation a liberation prolongee pour injection |
CA2192782C (fr) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production de microsphere |
EP0813887A3 (fr) * | 1996-06-20 | 1999-11-03 | Hisamitsu Pharmaceutical Co. Inc. | Appareil d'ionophorèse |
US20070274946A1 (en) * | 1999-04-15 | 2007-11-29 | Norwood Immunoloty, Ltd. | Tolerance to Graft Prior to Thymic Reactivation |
US20050020524A1 (en) * | 1999-04-15 | 2005-01-27 | Monash University | Hematopoietic stem cell gene therapy |
US20040258672A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Graft acceptance through manipulation of thymic regeneration |
US20040259803A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Disease prevention by reactivation of the thymus |
US20040265285A1 (en) * | 1999-04-15 | 2004-12-30 | Monash University | Normalization of defective T cell responsiveness through manipulation of thymic regeneration |
US20050042679A1 (en) * | 1999-04-15 | 2005-02-24 | Monash University | Diagnostic indicator of thymic function |
AUPR074500A0 (en) * | 2000-10-13 | 2000-11-09 | Monash University | Treatment of t cell disorders |
US20040241842A1 (en) * | 1999-04-15 | 2004-12-02 | Monash University | Stimulation of thymus for vaccination development |
ATE341562T1 (de) * | 1999-06-30 | 2006-10-15 | Takeda Pharmaceutical | Verfahren zur darstellung von lh-rh-derivaten |
JP4414517B2 (ja) | 1999-09-01 | 2010-02-10 | 久光製薬株式会社 | イオントフォレーシス用デバイス構造体 |
US20060088512A1 (en) * | 2001-10-15 | 2006-04-27 | Monash University | Treatment of T cell disorders |
DE60136490D1 (de) * | 2000-11-09 | 2008-12-18 | Neopharm Inc | Sn-38-lipidkomplexe und verfahren zu ihrer verwendung |
WO2003030864A1 (fr) * | 2001-05-29 | 2003-04-17 | Neopharm, Inc. | Formulation liposomale d'irinotecan |
US20060030578A1 (en) * | 2002-08-20 | 2006-02-09 | Neopharm, Inc. | Pharmaceutically active lipid based formulation of irinotecan |
AU2003296897A1 (en) * | 2002-08-20 | 2004-05-04 | Neopharm, Inc. | Pharmaceutical formulations of camptothecine derivatives |
EP3025722B1 (fr) | 2003-10-03 | 2020-05-27 | Thorn BioScience, LLC | Processus de synchronisation de l'ovulation pour la reproduction reglee sans detection des chaleurs |
GB0326632D0 (en) | 2003-11-14 | 2003-12-17 | Jagotec Ag | Dry powder formulations |
US20080279812A1 (en) * | 2003-12-05 | 2008-11-13 | Norwood Immunology, Ltd. | Disease Prevention and Vaccination Prior to Thymic Reactivation |
KR100651728B1 (ko) * | 2004-11-10 | 2006-12-06 | 한국전자통신연구원 | 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법 |
EP1773870B1 (fr) * | 2005-05-03 | 2009-12-16 | Novetide Ltd. | Méthode d'obtention de dérivés peptidiques |
EP1790656A1 (fr) | 2005-11-25 | 2007-05-30 | Nanokem S.A. | Synthèse en phase liquide du leuprolide |
US20070197435A1 (en) * | 2006-02-17 | 2007-08-23 | Webel Stephen K | Process for the synchronization of ovulation for timed breeding without heat detection |
DK2421545T3 (en) | 2009-04-23 | 2018-03-12 | Jbs United Animal Health Ii Llc | PROCEDURE AND COMPOSITION TO SYNCHRONIZE THE TIME OF INSEMINATION. |
EP2762133A1 (fr) | 2010-04-01 | 2014-08-06 | CHIESI FARMACEUTICI S.p.A. | PROCÉDÉ DE PRÉPARATION DE PARTICULES de véhicule POUR POUDRES SÈCHES À INHALER |
US20130060004A1 (en) * | 2010-05-07 | 2013-03-07 | Ananda Kuppanna | Novel Process For The Preparation Of Leuprolide And Its Pharmaceutically Acceptable Salts Thereof |
WO2012028745A1 (fr) | 2010-09-03 | 2012-03-08 | Pharmaterials Limited | Composition pharmaceutique adaptée pour une utilisation dans un inhalateur de poudre sèche |
CN104994865A (zh) | 2012-11-28 | 2015-10-21 | 杰碧斯联合动物健康第二有限责任公司 | 用于同步小母猪的授精时间的方法 |
CN103012564B (zh) * | 2013-01-15 | 2013-11-13 | 成都天台山制药有限公司 | 高纯度的曲普瑞林及其纯化方法 |
CN103012565B (zh) * | 2013-01-15 | 2014-07-16 | 成都天台山制药有限公司 | 一种曲普瑞林及其固相合成制备方法 |
CN104402977B (zh) * | 2014-12-08 | 2017-11-14 | 泰州启瑞医药科技有限公司 | 一种布舍瑞林的固液合成方法 |
US20190298836A1 (en) | 2016-11-02 | 2019-10-03 | Board Of Regents, The University Of Texas System | Dissolvable films and methods of their use |
US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO139560C (no) * | 1972-04-29 | 1979-04-04 | Takeda Chemical Industries Ltd | Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater |
US3914412A (en) * | 1973-10-11 | 1975-10-21 | Abbott Lab | {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity |
-
1974
- 1974-09-25 CS CS7400006578A patent/CS180644B2/cs unknown
- 1974-09-25 AT AT772674A patent/AT347054B/de active Protection Beyond IP Right Term
- 1974-09-26 GB GB4188274A patent/GB1434694A/en not_active Expired
- 1974-09-26 CH CH1304774A patent/CH603559A5/xx not_active IP Right Cessation
- 1974-09-26 SE SE7412140A patent/SE420717B/xx not_active IP Right Cessation
- 1974-09-26 DE DE2446005A patent/DE2446005C2/de not_active Expired
- 1974-09-27 HU HU74TA323A patent/HU173783B/hu unknown
- 1974-09-27 BE BE148990A patent/BE820451A/fr active Protection Beyond IP Right Term
- 1974-09-27 CA CA210,223A patent/CA1027114A/fr not_active Expired
- 1974-09-27 DK DK510374A patent/DK148305C/da active Protection Beyond IP Right Term
- 1974-09-27 NL NLAANVRAGE7412837,A patent/NL179289C/xx active Protection Beyond IP Right Term
- 1974-09-27 FR FR7432580A patent/FR2245375B1/fr not_active Expired
- 1974-09-28 ES ES430495A patent/ES430495A1/es not_active Expired
- 1974-09-30 NO NO743538A patent/NO143218C/no unknown
- 1974-09-30 FI FI2847/74A patent/FI61028C/fi active Protection Beyond IP Right Term
-
1975
- 1975-07-11 US US05/595,308 patent/US4008209A/en not_active Expired - Lifetime
-
1979
- 1979-03-22 HK HK155/79A patent/HK15579A/xx unknown
-
1993
- 1993-02-23 NL NL930015C patent/NL930015I2/nl unknown
- 1993-06-30 NL NL930121C patent/NL930121I1/nl unknown
-
1994
- 1994-08-18 NO NO1994010C patent/NO1994010I1/no unknown
Also Published As
Publication number | Publication date |
---|---|
NO143218C (no) | 1981-01-02 |
HK15579A (en) | 1979-03-30 |
NL7412837A (nl) | 1975-04-02 |
NO743538L (fr) | 1975-04-28 |
NL179289B (nl) | 1986-03-17 |
DE2446005A1 (de) | 1975-04-03 |
CS180644B2 (en) | 1978-01-31 |
ES430495A1 (es) | 1977-01-16 |
FI61028B (fi) | 1982-01-29 |
HU173783B (hu) | 1979-08-28 |
DK510374A (fr) | 1975-05-26 |
AT347054B (de) | 1978-12-11 |
NL179289C (nl) | 1986-08-18 |
FR2245375A1 (fr) | 1975-04-25 |
BE820451A (fr) | 1975-03-27 |
NL930015I2 (nl) | 1993-11-01 |
DE2446005C2 (de) | 1982-03-18 |
FI61028C (fi) | 1982-05-10 |
SE420717B (sv) | 1981-10-26 |
NL930121I1 (nl) | 1993-11-01 |
NL930015I1 (nl) | 1993-05-03 |
FR2245375B1 (fr) | 1978-07-21 |
CH603559A5 (fr) | 1978-08-31 |
ATA772674A (de) | 1978-04-15 |
CA1027114A (fr) | 1978-02-28 |
GB1434694A (en) | 1976-05-05 |
NO143218B (no) | 1980-09-22 |
DK148305B (da) | 1985-06-03 |
US4008209A (en) | 1977-02-15 |
FI284774A (fr) | 1975-03-30 |
NO1994010I1 (no) | 1994-08-18 |
DK148305C (da) | 1985-12-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE7412140L (fr) | ||
SE7502520L (fr) | ||
ES428530A1 (es) | Un metodo para preparar nuevos derivados de amida de nona- peptido. | |
ES8505335A1 (es) | Un metodo de preparar un peptido que inhibe la liberacion de gonadotropinas por la glandula pituitaria en mamiferos | |
AU571595B2 (en) | Gnrh antagonists | |
AU551892B2 (en) | Gnrh antagonists | |
ZA818829B (en) | Deca-undec-and tridecapeptides with thymic activity | |
ES462221A1 (es) | Procedimiento para preparar pentapeptidos e intermedios | |
GB1449397A (en) | Sunscreen composition | |
GB1530560A (en) | Cyclic hexapeptides | |
IE810703L (en) | Peptides | |
GB1420739A (en) | 3-alkenyl dibenzo-b,d-pyran compounds | |
EP0138604A3 (fr) | Antagonistes d'arginine vasopressine | |
ES443115A1 (es) | Procedimiento para la preparacion de un nuevo diedtr de 19- nor-testosterona-17beta-hidroxidelta4-estren-3-ona. | |
KR920014811A (ko) | 트리사이클릭 피리돈 유도체 | |
GB2010280A (en) | Somatostatin analogs | |
ES2002148A6 (es) | Procedimiento para la obtencion de etilenglicol | |
GB2008121A (en) | Tetrapeptides | |
ZA862570B (en) | Therapeutic decapeptides | |
GB1478553A (en) | Tetrapeptide amide and acid addition salts thereof | |
ES313434A1 (es) | Procedimiento para la obtencion de un producto dermatologico. | |
ES473646A1 (es) | Un procedimiento para la preparacion de nuevos esteroides dela serie del pregnano | |
GB962943A (en) | Improvements in or relating to the preparation of penicillins | |
JPS53116354A (en) | Preparation of 2,4-dicyclohexyl-2-methylpentanone | |
GB1458218A (en) | Azabicycloalkanes and process for their preparation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
SPCG | Supplementary protection certificate granted |
Free format text: 7412140, EXPIRES: 19990723 |
|
NUG | Patent has lapsed |
Ref document number: 7412140-1 Effective date: 19940810 Format of ref document f/p: F |