NL179289B - Werkwijze ter bereiding van nonapeptide-amidederivaten, en farmaceutische preparaten met ovulatieopwekkende werking daaruit. - Google Patents
Werkwijze ter bereiding van nonapeptide-amidederivaten, en farmaceutische preparaten met ovulatieopwekkende werking daaruit.Info
- Publication number
- NL179289B NL179289B NLAANVRAGE7412837,A NL7412837A NL179289B NL 179289 B NL179289 B NL 179289B NL 7412837 A NL7412837 A NL 7412837A NL 179289 B NL179289 B NL 179289B
- Authority
- NL
- Netherlands
- Prior art keywords
- ovulative
- activities
- preparation
- pharmaceutical preparations
- amide derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10995173A JPS5314072B2 (nl) | 1973-09-29 | 1973-09-29 | |
JP2744274A JPS5726506B2 (nl) | 1974-03-08 | 1974-03-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
NL7412837A NL7412837A (nl) | 1975-04-02 |
NL179289B true NL179289B (nl) | 1986-03-17 |
NL179289C NL179289C (nl) | 1986-08-18 |
Family
ID=26365357
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NLAANVRAGE7412837,A NL179289C (nl) | 1973-09-29 | 1974-09-27 | Werkwijze ter bereiding van nonapeptide-amidederivaten, en farmaceutische preparaten met ovulatieopwekkende werking daaruit. |
NL930015C NL930015I2 (nl) | 1973-09-29 | 1993-02-23 | Werkwijze ter bereiding van nonapepide-aminederivaten, en farmaceutische preparaten met ovulatie-opwekkende werking daaruit. |
NL930121C NL930121I1 (nl) | 1973-09-29 | 1993-06-30 | Werkwijze ter bereiding van nonapeptide-amidederivaten en farmaceutische preparaten met ovulatieopw ekkende werking daaruit |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL930015C NL930015I2 (nl) | 1973-09-29 | 1993-02-23 | Werkwijze ter bereiding van nonapepide-aminederivaten, en farmaceutische preparaten met ovulatie-opwekkende werking daaruit. |
NL930121C NL930121I1 (nl) | 1973-09-29 | 1993-06-30 | Werkwijze ter bereiding van nonapeptide-amidederivaten en farmaceutische preparaten met ovulatieopw ekkende werking daaruit |
Country Status (17)
Country | Link |
---|---|
US (1) | US4008209A (nl) |
AT (1) | AT347054B (nl) |
BE (1) | BE820451A (nl) |
CA (1) | CA1027114A (nl) |
CH (1) | CH603559A5 (nl) |
CS (1) | CS180644B2 (nl) |
DE (1) | DE2446005C2 (nl) |
DK (1) | DK148305C (nl) |
ES (1) | ES430495A1 (nl) |
FI (1) | FI61028C (nl) |
FR (1) | FR2245375B1 (nl) |
GB (1) | GB1434694A (nl) |
HK (1) | HK15579A (nl) |
HU (1) | HU173783B (nl) |
NL (3) | NL179289C (nl) |
NO (2) | NO143218C (nl) |
SE (1) | SE420717B (nl) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2735515A1 (de) * | 1977-08-06 | 1979-02-22 | Hoechst Ag | Verwendung von lh-rh-peptiden als antikonzeptive |
FR2450109B1 (fr) * | 1977-11-08 | 1986-03-28 | Roussel Uclaf | Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes |
US4215038A (en) * | 1978-10-16 | 1980-07-29 | The Salk Institute For Biological Studies | Peptides which inhibit gonadal function |
US4359312A (en) * | 1978-08-15 | 1982-11-16 | Zumtobel Kg | Reciprocating pump for the pulsation-free delivery of a liquid |
US4256737A (en) * | 1979-06-11 | 1981-03-17 | Syntex (U.S.A.) Inc. | Long acting depot injectable formulations for LH-RH analogues |
DE3020941A1 (de) * | 1980-06-03 | 1981-12-17 | Hoechst Ag, 6000 Frankfurt | Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung |
ZA815447B (en) * | 1980-08-29 | 1982-08-25 | Salk Inst For Biological Studi | Peptides affecting gonadal function |
US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
CS230614B1 (en) * | 1982-08-06 | 1984-08-13 | Martin Cs Flegel | Analogues of realising factor for luteining and folliculstimulated hormon |
US4491541A (en) * | 1982-11-10 | 1985-01-01 | Farmitalia Carlo Erba | Peptides |
IT1178775B (it) * | 1983-12-23 | 1987-09-16 | Konzponti Valto Es Hitelbank R | Derivati della gonadoliberina e procedimento per la loro preparazione |
HU189394B (en) * | 1983-12-23 | 1986-06-30 | Koezponti Valto- Es Hitelbank Rt Innovacios Alap,Hu | Method for producing spermatozoa suitable for fertilization from mature fishes |
DE3411224A1 (de) * | 1984-03-27 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren |
HU193093B (en) * | 1985-04-16 | 1987-08-28 | Innofinance | Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation |
HU193607B (en) * | 1985-07-18 | 1987-11-30 | Innofinance Altalanos Innovaci | Process for production of sexual products applyable for natural or artificial insemination for mammates |
US4762717A (en) * | 1986-03-21 | 1988-08-09 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive |
US4897268A (en) * | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
US5068221A (en) * | 1989-05-09 | 1991-11-26 | Mathias John R | Treatment of motility disorders with a gnrh analog |
JP2653255B2 (ja) | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
CA2050425A1 (en) | 1990-09-03 | 1992-03-04 | Yoshiaki Uda | Pharmaceutical composition and its mucous use |
ZA918168B (en) | 1990-10-16 | 1993-04-14 | Takeda Chemical Industries Ltd | Prolonged release preparation and polymers thereof. |
US5434136A (en) * | 1990-12-14 | 1995-07-18 | Mathias; John R. | Treatment of motility disorders with a GNRH analog |
US5518730A (en) * | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
DK0582459T3 (da) | 1992-08-07 | 1998-04-27 | Takeda Chemical Industries Ltd | Fremstilling af mikrokapsler af vandopløselige lægemidler |
EP1138345A3 (en) | 1993-09-22 | 2003-06-04 | Hisamitsu Pharmaceutical Co., Inc. | A matrix for iontophoreses |
US5594091A (en) * | 1994-02-21 | 1997-01-14 | Takeda Chemical Industries, Ltd. | Matrix for sustained-release preparation |
US6117455A (en) * | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
IL115099A (en) | 1994-10-14 | 1999-04-11 | Upjohn Co | Lyophilizate of phospholipid complex of water insoluble camptothecins |
US5837281A (en) | 1995-03-17 | 1998-11-17 | Takeda Chemical Industries, Ltd. | Stabilized interface for iontophoresis |
CA2192773C (en) | 1995-12-15 | 2008-09-23 | Hiroaki Okada | Production of sustained-release preparation for injection |
CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
EP0813887A3 (en) * | 1996-06-20 | 1999-11-03 | Hisamitsu Pharmaceutical Co. Inc. | A device structure for iontophoresis |
US20070274946A1 (en) * | 1999-04-15 | 2007-11-29 | Norwood Immunoloty, Ltd. | Tolerance to Graft Prior to Thymic Reactivation |
US20050020524A1 (en) * | 1999-04-15 | 2005-01-27 | Monash University | Hematopoietic stem cell gene therapy |
US20040258672A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Graft acceptance through manipulation of thymic regeneration |
US20040259803A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Disease prevention by reactivation of the thymus |
US20040265285A1 (en) * | 1999-04-15 | 2004-12-30 | Monash University | Normalization of defective T cell responsiveness through manipulation of thymic regeneration |
US20050042679A1 (en) * | 1999-04-15 | 2005-02-24 | Monash University | Diagnostic indicator of thymic function |
AUPR074500A0 (en) * | 2000-10-13 | 2000-11-09 | Monash University | Treatment of t cell disorders |
US20040241842A1 (en) * | 1999-04-15 | 2004-12-02 | Monash University | Stimulation of thymus for vaccination development |
ATE341562T1 (de) * | 1999-06-30 | 2006-10-15 | Takeda Pharmaceutical | Verfahren zur darstellung von lh-rh-derivaten |
JP4414517B2 (ja) | 1999-09-01 | 2010-02-10 | 久光製薬株式会社 | イオントフォレーシス用デバイス構造体 |
US20060088512A1 (en) * | 2001-10-15 | 2006-04-27 | Monash University | Treatment of T cell disorders |
DE60136490D1 (de) * | 2000-11-09 | 2008-12-18 | Neopharm Inc | Sn-38-lipidkomplexe und verfahren zu ihrer verwendung |
WO2003030864A1 (en) * | 2001-05-29 | 2003-04-17 | Neopharm, Inc. | Liposomal formulation of irinotecan |
US20060030578A1 (en) * | 2002-08-20 | 2006-02-09 | Neopharm, Inc. | Pharmaceutically active lipid based formulation of irinotecan |
AU2003296897A1 (en) * | 2002-08-20 | 2004-05-04 | Neopharm, Inc. | Pharmaceutical formulations of camptothecine derivatives |
EP3025722B1 (en) | 2003-10-03 | 2020-05-27 | Thorn BioScience, LLC | Process for the synchronization of ovulation for timed breeding without heat detection |
GB0326632D0 (en) | 2003-11-14 | 2003-12-17 | Jagotec Ag | Dry powder formulations |
US20080279812A1 (en) * | 2003-12-05 | 2008-11-13 | Norwood Immunology, Ltd. | Disease Prevention and Vaccination Prior to Thymic Reactivation |
KR100651728B1 (ko) * | 2004-11-10 | 2006-12-06 | 한국전자통신연구원 | 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법 |
EP1773870B1 (en) * | 2005-05-03 | 2009-12-16 | Novetide Ltd. | Methods for the production of peptide having a c-terminal amide |
EP1790656A1 (en) | 2005-11-25 | 2007-05-30 | Nanokem S.A. | Solution-phase synthesis of leuprolide |
US20070197435A1 (en) * | 2006-02-17 | 2007-08-23 | Webel Stephen K | Process for the synchronization of ovulation for timed breeding without heat detection |
DK2421545T3 (en) | 2009-04-23 | 2018-03-12 | Jbs United Animal Health Ii Llc | PROCEDURE AND COMPOSITION TO SYNCHRONIZE THE TIME OF INSEMINATION. |
EP2762133A1 (en) | 2010-04-01 | 2014-08-06 | CHIESI FARMACEUTICI S.p.A. | Process for preparing carrier particles for dry powders for inhalation |
US20130060004A1 (en) * | 2010-05-07 | 2013-03-07 | Ananda Kuppanna | Novel Process For The Preparation Of Leuprolide And Its Pharmaceutically Acceptable Salts Thereof |
WO2012028745A1 (en) | 2010-09-03 | 2012-03-08 | Pharmaterials Limited | Pharmaceutical composition suitable for use in a dry powder inhaler |
CN104994865A (zh) | 2012-11-28 | 2015-10-21 | 杰碧斯联合动物健康第二有限责任公司 | 用于同步小母猪的授精时间的方法 |
CN103012564B (zh) * | 2013-01-15 | 2013-11-13 | 成都天台山制药有限公司 | 高纯度的曲普瑞林及其纯化方法 |
CN103012565B (zh) * | 2013-01-15 | 2014-07-16 | 成都天台山制药有限公司 | 一种曲普瑞林及其固相合成制备方法 |
CN104402977B (zh) * | 2014-12-08 | 2017-11-14 | 泰州启瑞医药科技有限公司 | 一种布舍瑞林的固液合成方法 |
US20190298836A1 (en) | 2016-11-02 | 2019-10-03 | Board Of Regents, The University Of Texas System | Dissolvable films and methods of their use |
US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO139560C (no) * | 1972-04-29 | 1979-04-04 | Takeda Chemical Industries Ltd | Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater |
US3914412A (en) * | 1973-10-11 | 1975-10-21 | Abbott Lab | {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity |
-
1974
- 1974-09-25 CS CS7400006578A patent/CS180644B2/cs unknown
- 1974-09-25 AT AT772674A patent/AT347054B/de active Protection Beyond IP Right Term
- 1974-09-26 GB GB4188274A patent/GB1434694A/en not_active Expired
- 1974-09-26 CH CH1304774A patent/CH603559A5/xx not_active IP Right Cessation
- 1974-09-26 SE SE7412140A patent/SE420717B/xx not_active IP Right Cessation
- 1974-09-26 DE DE2446005A patent/DE2446005C2/de not_active Expired
- 1974-09-27 HU HU74TA323A patent/HU173783B/hu unknown
- 1974-09-27 BE BE148990A patent/BE820451A/xx active Protection Beyond IP Right Term
- 1974-09-27 CA CA210,223A patent/CA1027114A/en not_active Expired
- 1974-09-27 DK DK510374A patent/DK148305C/da active Protection Beyond IP Right Term
- 1974-09-27 NL NLAANVRAGE7412837,A patent/NL179289C/nl active Protection Beyond IP Right Term
- 1974-09-27 FR FR7432580A patent/FR2245375B1/fr not_active Expired
- 1974-09-28 ES ES430495A patent/ES430495A1/es not_active Expired
- 1974-09-30 NO NO743538A patent/NO143218C/no unknown
- 1974-09-30 FI FI2847/74A patent/FI61028C/fi active Protection Beyond IP Right Term
-
1975
- 1975-07-11 US US05/595,308 patent/US4008209A/en not_active Expired - Lifetime
-
1979
- 1979-03-22 HK HK155/79A patent/HK15579A/xx unknown
-
1993
- 1993-02-23 NL NL930015C patent/NL930015I2/nl unknown
- 1993-06-30 NL NL930121C patent/NL930121I1/nl unknown
-
1994
- 1994-08-18 NO NO1994010C patent/NO1994010I1/no unknown
Also Published As
Publication number | Publication date |
---|---|
NO143218C (no) | 1981-01-02 |
HK15579A (en) | 1979-03-30 |
NL7412837A (nl) | 1975-04-02 |
NO743538L (nl) | 1975-04-28 |
DE2446005A1 (de) | 1975-04-03 |
CS180644B2 (en) | 1978-01-31 |
ES430495A1 (es) | 1977-01-16 |
FI61028B (fi) | 1982-01-29 |
HU173783B (hu) | 1979-08-28 |
DK510374A (nl) | 1975-05-26 |
AT347054B (de) | 1978-12-11 |
NL179289C (nl) | 1986-08-18 |
FR2245375A1 (nl) | 1975-04-25 |
BE820451A (fr) | 1975-03-27 |
NL930015I2 (nl) | 1993-11-01 |
DE2446005C2 (de) | 1982-03-18 |
FI61028C (fi) | 1982-05-10 |
SE420717B (sv) | 1981-10-26 |
SE7412140L (nl) | 1975-04-01 |
NL930121I1 (nl) | 1993-11-01 |
NL930015I1 (nl) | 1993-05-03 |
FR2245375B1 (nl) | 1978-07-21 |
CH603559A5 (nl) | 1978-08-31 |
ATA772674A (de) | 1978-04-15 |
CA1027114A (en) | 1978-02-28 |
GB1434694A (en) | 1976-05-05 |
NO143218B (no) | 1980-09-22 |
DK148305B (da) | 1985-06-03 |
US4008209A (en) | 1977-02-15 |
FI284774A (nl) | 1975-03-30 |
NO1994010I1 (no) | 1994-08-18 |
DK148305C (da) | 1985-12-02 |
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Legal Events
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BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
A85 | Still pending on 85-01-01 | ||
BK | Erratum |
Free format text: CORRECTION TO PAMPHLET |
|
AC1 | Application for a supplementary protection certificate |
Free format text: 930015, 930223 |
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