NL179289B - Werkwijze ter bereiding van nonapeptide-amidederivaten, en farmaceutische preparaten met ovulatieopwekkende werking daaruit. - Google Patents
Werkwijze ter bereiding van nonapeptide-amidederivaten, en farmaceutische preparaten met ovulatieopwekkende werking daaruit.Info
- Publication number
- NL179289B NL179289B NLAANVRAGE7412837,A NL7412837A NL179289B NL 179289 B NL179289 B NL 179289B NL 7412837 A NL7412837 A NL 7412837A NL 179289 B NL179289 B NL 179289B
- Authority
- NL
- Netherlands
- Prior art keywords
- ovulative
- activities
- preparation
- pharmaceutical preparations
- amide derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10995173A JPS5314072B2 (nl) | 1973-09-29 | 1973-09-29 | |
JP2744274A JPS5726506B2 (nl) | 1974-03-08 | 1974-03-08 |
Publications (3)
Publication Number | Publication Date |
---|---|
NL7412837A NL7412837A (nl) | 1975-04-02 |
NL179289B true NL179289B (nl) | 1986-03-17 |
NL179289C NL179289C (nl) | 1986-08-18 |
Family
ID=26365357
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NLAANVRAGE7412837,A NL179289C (nl) | 1973-09-29 | 1974-09-27 | Werkwijze ter bereiding van nonapeptide-amidederivaten, en farmaceutische preparaten met ovulatieopwekkende werking daaruit. |
NL930015C NL930015I2 (nl) | 1973-09-29 | 1993-02-23 | Werkwijze ter bereiding van nonapepide-aminederivaten, en farmaceutische preparaten met ovulatie-opwekkende werking daaruit. |
NL930121C NL930121I1 (nl) | 1973-09-29 | 1993-06-30 | Werkwijze ter bereiding van nonapeptide-amidederivaten en farmaceutische preparaten met ovulatieopw ekkende werking daaruit |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL930015C NL930015I2 (nl) | 1973-09-29 | 1993-02-23 | Werkwijze ter bereiding van nonapepide-aminederivaten, en farmaceutische preparaten met ovulatie-opwekkende werking daaruit. |
NL930121C NL930121I1 (nl) | 1973-09-29 | 1993-06-30 | Werkwijze ter bereiding van nonapeptide-amidederivaten en farmaceutische preparaten met ovulatieopw ekkende werking daaruit |
Country Status (17)
Country | Link |
---|---|
US (1) | US4008209A (nl) |
AT (1) | AT347054B (nl) |
BE (1) | BE820451A (nl) |
CA (1) | CA1027114A (nl) |
CH (1) | CH603559A5 (nl) |
CS (1) | CS180644B2 (nl) |
DE (1) | DE2446005C2 (nl) |
DK (1) | DK148305C (nl) |
ES (1) | ES430495A1 (nl) |
FI (1) | FI61028C (nl) |
FR (1) | FR2245375B1 (nl) |
GB (1) | GB1434694A (nl) |
HK (1) | HK15579A (nl) |
HU (1) | HU173783B (nl) |
NL (3) | NL179289C (nl) |
NO (2) | NO143218C (nl) |
SE (1) | SE420717B (nl) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2735515A1 (de) * | 1977-08-06 | 1979-02-22 | Hoechst Ag | Verwendung von lh-rh-peptiden als antikonzeptive |
FR2450109B1 (fr) * | 1977-11-08 | 1986-03-28 | Roussel Uclaf | Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes |
US4215038A (en) * | 1978-10-16 | 1980-07-29 | The Salk Institute For Biological Studies | Peptides which inhibit gonadal function |
US4359312A (en) * | 1978-08-15 | 1982-11-16 | Zumtobel Kg | Reciprocating pump for the pulsation-free delivery of a liquid |
US4256737A (en) * | 1979-06-11 | 1981-03-17 | Syntex (U.S.A.) Inc. | Long acting depot injectable formulations for LH-RH analogues |
DE3020941A1 (de) * | 1980-06-03 | 1981-12-17 | Hoechst Ag, 6000 Frankfurt | Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung |
ZA815447B (en) * | 1980-08-29 | 1982-08-25 | Salk Inst For Biological Studi | Peptides affecting gonadal function |
US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
US4659696A (en) * | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
CS230614B1 (en) * | 1982-08-06 | 1984-08-13 | Martin Cs Flegel | Analogues of realising factor for luteining and folliculstimulated hormon |
US4491541A (en) * | 1982-11-10 | 1985-01-01 | Farmitalia Carlo Erba | Peptides |
IT1178775B (it) * | 1983-12-23 | 1987-09-16 | Konzponti Valto Es Hitelbank R | Derivati della gonadoliberina e procedimento per la loro preparazione |
HU189394B (en) * | 1983-12-23 | 1986-06-30 | Koezponti Valto- Es Hitelbank Rt Innovacios Alap,Hu | Method for producing spermatozoa suitable for fertilization from mature fishes |
DE3411224A1 (de) * | 1984-03-27 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren |
HU193093B (en) * | 1985-04-16 | 1987-08-28 | Innofinance | Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation |
HU193607B (en) * | 1985-07-18 | 1987-11-30 | Innofinance Altalanos Innovaci | Process for production of sexual products applyable for natural or artificial insemination for mammates |
US4762717A (en) * | 1986-03-21 | 1988-08-09 | The General Hospital Corporation | Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use as a contraceptive |
US4897268A (en) * | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
US5068221A (en) * | 1989-05-09 | 1991-11-26 | Mathias John R | Treatment of motility disorders with a gnrh analog |
JP2653255B2 (ja) | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
CA2050425A1 (en) | 1990-09-03 | 1992-03-04 | Yoshiaki Uda | Pharmaceutical composition and its mucous use |
NO302481B1 (no) | 1990-10-16 | 1998-03-09 | Takeda Chemical Industries Ltd | Polymer for et preparat med forlenget frigjöring, samt preparat med forlenget frigjöring |
US5434136A (en) * | 1990-12-14 | 1995-07-18 | Mathias; John R. | Treatment of motility disorders with a GNRH analog |
US5518730A (en) * | 1992-06-03 | 1996-05-21 | Fuisz Technologies Ltd. | Biodegradable controlled release flash flow melt-spun delivery system |
ES2110573T3 (es) | 1992-08-07 | 1998-02-16 | Takeda Chemical Industries Ltd | Produccion de microcapsulas de farmacos solubles en agua. |
DE69429603T2 (de) | 1993-09-22 | 2002-08-14 | Hisamitsu Pharmaceutical Co., Inc. | Iontophoresematrix |
US5594091A (en) * | 1994-02-21 | 1997-01-14 | Takeda Chemical Industries, Ltd. | Matrix for sustained-release preparation |
US6117455A (en) | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
IL115099A (en) | 1994-10-14 | 1999-04-11 | Upjohn Co | Lyophilizate of phospholipid complex of water insoluble camptothecins |
US5837281A (en) | 1995-03-17 | 1998-11-17 | Takeda Chemical Industries, Ltd. | Stabilized interface for iontophoresis |
CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
CA2192773C (en) | 1995-12-15 | 2008-09-23 | Hiroaki Okada | Production of sustained-release preparation for injection |
US5908400A (en) * | 1996-06-20 | 1999-06-01 | Hisamitsu Pharmaceutical Co., Inc. | Device structure for iontophoresis |
AUPR074500A0 (en) * | 2000-10-13 | 2000-11-09 | Monash University | Treatment of t cell disorders |
US20050042679A1 (en) * | 1999-04-15 | 2005-02-24 | Monash University | Diagnostic indicator of thymic function |
US20040265285A1 (en) * | 1999-04-15 | 2004-12-30 | Monash University | Normalization of defective T cell responsiveness through manipulation of thymic regeneration |
US20040258672A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Graft acceptance through manipulation of thymic regeneration |
US20040259803A1 (en) * | 1999-04-15 | 2004-12-23 | Monash University | Disease prevention by reactivation of the thymus |
US20070274946A1 (en) * | 1999-04-15 | 2007-11-29 | Norwood Immunoloty, Ltd. | Tolerance to Graft Prior to Thymic Reactivation |
US20050020524A1 (en) * | 1999-04-15 | 2005-01-27 | Monash University | Hematopoietic stem cell gene therapy |
US20040241842A1 (en) * | 1999-04-15 | 2004-12-02 | Monash University | Stimulation of thymus for vaccination development |
EP1207167B1 (en) * | 1999-06-30 | 2006-10-04 | Takeda Pharmaceutical Company Limited | Process for the preparation of lh-rh derivatives |
JP4414517B2 (ja) | 1999-09-01 | 2010-02-10 | 久光製薬株式会社 | イオントフォレーシス用デバイス構造体 |
US20060088512A1 (en) * | 2001-10-15 | 2006-04-27 | Monash University | Treatment of T cell disorders |
ATE413164T1 (de) * | 2000-11-09 | 2008-11-15 | Neopharm Inc | Sn-38-lipidkomplexe und verfahren zu ihrer verwendung |
WO2003030864A1 (en) * | 2001-05-29 | 2003-04-17 | Neopharm, Inc. | Liposomal formulation of irinotecan |
US20060030578A1 (en) * | 2002-08-20 | 2006-02-09 | Neopharm, Inc. | Pharmaceutically active lipid based formulation of irinotecan |
AU2003296897A1 (en) * | 2002-08-20 | 2004-05-04 | Neopharm, Inc. | Pharmaceutical formulations of camptothecine derivatives |
PT1684782E (pt) | 2003-10-03 | 2015-12-21 | Thorn Bioscience Llc | Processo para a sincronização da ovulação para reprodução regulada sem detecção do cio |
GB0326632D0 (en) | 2003-11-14 | 2003-12-17 | Jagotec Ag | Dry powder formulations |
US20080279812A1 (en) * | 2003-12-05 | 2008-11-13 | Norwood Immunology, Ltd. | Disease Prevention and Vaccination Prior to Thymic Reactivation |
KR100651728B1 (ko) * | 2004-11-10 | 2006-12-06 | 한국전자통신연구원 | 정착기를 갖는 전자 소자용 화합물 및 이를 포함하는 전자소자와 이들의 제조 방법 |
EP2119725A1 (en) | 2005-05-03 | 2009-11-18 | Novetide Ltd. | Methods for the production of leuprolide |
EP1790656A1 (en) | 2005-11-25 | 2007-05-30 | Nanokem S.A. | Solution-phase synthesis of leuprolide |
US20070197435A1 (en) * | 2006-02-17 | 2007-08-23 | Webel Stephen K | Process for the synchronization of ovulation for timed breeding without heat detection |
ES2661240T3 (es) | 2009-04-23 | 2018-03-28 | Jbs United Animal Health Ii Llc | Método y composición para sincronizar el momento de inseminación |
BR112012024059B1 (pt) | 2010-04-01 | 2021-06-01 | Chiesi Farmaceutici S.P.A. | Processo de preparo de um excipiente para composições farmacêuticas em pó para inalação, partículas carreadoras para uma formulação farmacêutica de pó seco, composição farmacêutica em forma de pó seco para inalação e inalador de pó seco |
EP2566883A1 (en) | 2010-05-07 | 2013-03-13 | Mylan Laboratories, Limited | Novel process for the preparation of leuprolide and its pharmaceutically acceptable salts thereof |
WO2012028745A1 (en) | 2010-09-03 | 2012-03-08 | Pharmaterials Limited | Pharmaceutical composition suitable for use in a dry powder inhaler |
US9724380B2 (en) | 2012-11-28 | 2017-08-08 | Jbs United Animal Health Ii Llc | Method and compositions for synchronizing time of insemination in gilts |
CN103012564B (zh) * | 2013-01-15 | 2013-11-13 | 成都天台山制药有限公司 | 高纯度的曲普瑞林及其纯化方法 |
CN103012565B (zh) * | 2013-01-15 | 2014-07-16 | 成都天台山制药有限公司 | 一种曲普瑞林及其固相合成制备方法 |
CN104402977B (zh) * | 2014-12-08 | 2017-11-14 | 泰州启瑞医药科技有限公司 | 一种布舍瑞林的固液合成方法 |
EP3534974B1 (en) | 2016-11-02 | 2024-08-21 | Board of Regents, The University of Texas System | Dissolvable films and methods of their use |
US11376220B2 (en) | 2017-06-30 | 2022-07-05 | Therio, LLC | Single-injection methods and formulations to induce and control multiple ovarian follicles in bovine, caprine, ovine, camelid and other female animals |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO139560C (no) * | 1972-04-29 | 1979-04-04 | Takeda Chemical Industries Ltd | Analogifremgangsmaate til fremstilling av terapeutisk virksomme nonapeptidamid-derivater |
US3914412A (en) * | 1973-10-11 | 1975-10-21 | Abbott Lab | {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity |
-
1974
- 1974-09-25 AT AT772674A patent/AT347054B/de active Protection Beyond IP Right Term
- 1974-09-25 CS CS7400006578A patent/CS180644B2/cs unknown
- 1974-09-26 DE DE2446005A patent/DE2446005C2/de not_active Expired
- 1974-09-26 CH CH1304774A patent/CH603559A5/xx not_active IP Right Cessation
- 1974-09-26 GB GB4188274A patent/GB1434694A/en not_active Expired
- 1974-09-26 SE SE7412140A patent/SE420717B/xx not_active IP Right Cessation
- 1974-09-27 NL NLAANVRAGE7412837,A patent/NL179289C/nl active Protection Beyond IP Right Term
- 1974-09-27 CA CA210,223A patent/CA1027114A/en not_active Expired
- 1974-09-27 BE BE148990A patent/BE820451A/xx active Protection Beyond IP Right Term
- 1974-09-27 DK DK510374A patent/DK148305C/da active Protection Beyond IP Right Term
- 1974-09-27 HU HU74TA323A patent/HU173783B/hu unknown
- 1974-09-27 FR FR7432580A patent/FR2245375B1/fr not_active Expired
- 1974-09-28 ES ES430495A patent/ES430495A1/es not_active Expired
- 1974-09-30 NO NO743538A patent/NO143218C/no unknown
- 1974-09-30 FI FI2847/74A patent/FI61028C/fi active Protection Beyond IP Right Term
-
1975
- 1975-07-11 US US05/595,308 patent/US4008209A/en not_active Expired - Lifetime
-
1979
- 1979-03-22 HK HK155/79A patent/HK15579A/xx unknown
-
1993
- 1993-02-23 NL NL930015C patent/NL930015I2/nl unknown
- 1993-06-30 NL NL930121C patent/NL930121I1/nl unknown
-
1994
- 1994-08-18 NO NO1994010C patent/NO1994010I1/no unknown
Also Published As
Publication number | Publication date |
---|---|
CH603559A5 (nl) | 1978-08-31 |
BE820451A (fr) | 1975-03-27 |
NO143218C (no) | 1981-01-02 |
US4008209A (en) | 1977-02-15 |
NL930015I2 (nl) | 1993-11-01 |
NO143218B (no) | 1980-09-22 |
NO1994010I1 (no) | 1994-08-18 |
FR2245375A1 (nl) | 1975-04-25 |
DE2446005A1 (de) | 1975-04-03 |
SE7412140L (nl) | 1975-04-01 |
CA1027114A (en) | 1978-02-28 |
HK15579A (en) | 1979-03-30 |
CS180644B2 (en) | 1978-01-31 |
FI284774A (nl) | 1975-03-30 |
DK148305B (da) | 1985-06-03 |
DE2446005C2 (de) | 1982-03-18 |
SE420717B (sv) | 1981-10-26 |
FR2245375B1 (nl) | 1978-07-21 |
ES430495A1 (es) | 1977-01-16 |
NL930015I1 (nl) | 1993-05-03 |
NL930121I1 (nl) | 1993-11-01 |
HU173783B (hu) | 1979-08-28 |
NO743538L (nl) | 1975-04-28 |
NL179289C (nl) | 1986-08-18 |
DK510374A (nl) | 1975-05-26 |
FI61028B (fi) | 1982-01-29 |
NL7412837A (nl) | 1975-04-02 |
DK148305C (da) | 1985-12-02 |
ATA772674A (de) | 1978-04-15 |
GB1434694A (en) | 1976-05-05 |
FI61028C (fi) | 1982-05-10 |
AT347054B (de) | 1978-12-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
A85 | Still pending on 85-01-01 | ||
BK | Erratum |
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