GB1458218A - Azabicycloalkanes and process for their preparation - Google Patents
Azabicycloalkanes and process for their preparationInfo
- Publication number
- GB1458218A GB1458218A GB2767476A GB2767476A GB1458218A GB 1458218 A GB1458218 A GB 1458218A GB 2767476 A GB2767476 A GB 2767476A GB 2767476 A GB2767476 A GB 2767476A GB 1458218 A GB1458218 A GB 1458218A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compound
- produce
- nitromethylene
- hal
- aminomethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1458218 Azabicycloalkanes SCIENCE UNION ET CIE SOC FRANCAISE DE RECHERCHE MEDICALE 13 Dec 1974 [14 Dec 1973] 27674/76 Divided out of 1458217 Heading C2C Novel compounds of the Formula I wherein n is 0, 1 or 2, R is a saturated or unsaturated aliphatic hydrocarbon having up to 5 carbon atoms and R<SP>1</SP> is hydrogen and R<SP>2</SP> is aminomethyl or R<SP>1</SP> and R<SP>2</SP> together are oxygen or nitromethylene may be prepared by (1) reacting a compound V with a compound R-hal wherein hal is halogen, in the presence of sodium hydride to produce a compound I in which R<SP>1</SP> and R<SP>2</SP> together are oxygen, optionally followed by reaction with dimethyl sulphate, sodium methylate and nitromethane to produce a compound I in which R<SP>1</SP> and R<SP>2</SP> together are nitromethylene, optionally followed by reduction to produce a compound I in which R<SP>1</SP> is hydrogen and R<SP>2</SP> is aminomethyl. The final product may be used to prepare pharmaceutically active compounds claimed in Specification 1,458,217.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2767476A GB1458218A (en) | 1973-12-14 | 1973-12-14 | Azabicycloalkanes and process for their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2767476A GB1458218A (en) | 1973-12-14 | 1973-12-14 | Azabicycloalkanes and process for their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1458218A true GB1458218A (en) | 1976-12-08 |
Family
ID=10263438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2767476A Expired GB1458218A (en) | 1973-12-14 | 1973-12-14 | Azabicycloalkanes and process for their preparation |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB1458218A (en) |
-
1973
- 1973-12-14 GB GB2767476A patent/GB1458218A/en not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |