GB1374367A - Propionamide derivative a method of making it and therapeutic compositions containing it - Google Patents

Propionamide derivative a method of making it and therapeutic compositions containing it

Info

Publication number
GB1374367A
GB1374367A GB3548172A GB3548172A GB1374367A GB 1374367 A GB1374367 A GB 1374367A GB 3548172 A GB3548172 A GB 3548172A GB 3548172 A GB3548172 A GB 3548172A GB 1374367 A GB1374367 A GB 1374367A
Authority
GB
United Kingdom
Prior art keywords
acid addition
addition salts
making
compositions containing
therapeutic compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3548172A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra USA Inc
Original Assignee
Astra Pharmaceutical Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceutical Products Inc filed Critical Astra Pharmaceutical Products Inc
Publication of GB1374367A publication Critical patent/GB1374367A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated

Abstract

1374367 2 - Amino - 2<SP>1</SP>,6<SP>1</SP> - propionoxylidide ASTRA PHARMACEUTICAL PRODUCTS Inc 28 July 1972 [28 July 1971] 35481/72 Heading C2C The novel title compound and acid addition salts thereof are prepared by reacting a 2-halo- 2<SP>1</SP>,6<SP>1</SP>-propionoxylidide, wherein halo is Cl, Br or I, with ammonia, and, if desired, converting the resulting base into acid addition salts. Pharmaceutical compositions, suitable for oral or parenteral administration, contain the above novel compound or therapeutically acceptable acid addition salts thereof together with pharmaceutically acceptable carriers. The compound possesses antiarrhythmic properties.
GB3548172A 1971-07-28 1972-07-20 Propionamide derivative a method of making it and therapeutic compositions containing it Expired GB1374367A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16703171A 1971-07-28 1971-07-28

Publications (1)

Publication Number Publication Date
GB1374367A true GB1374367A (en) 1974-11-20

Family

ID=22605664

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3548172A Expired GB1374367A (en) 1971-07-28 1972-07-20 Propionamide derivative a method of making it and therapeutic compositions containing it

Country Status (22)

Country Link
JP (1) JPS565220B1 (en)
AR (1) AR193748A1 (en)
AT (1) AT317185B (en)
AU (1) AU476000B2 (en)
BE (1) BE786875A (en)
BR (1) BR7205069D0 (en)
CA (1) CA982148A (en)
CH (1) CH574397A5 (en)
CS (1) CS171171B2 (en)
DD (1) DD101389A5 (en)
DK (1) DK142843B (en)
ES (1) ES404739A1 (en)
FI (1) FI55492C (en)
FR (1) FR2147277B1 (en)
GB (1) GB1374367A (en)
HU (1) HU163818B (en)
IE (1) IE36607B1 (en)
NL (1) NL176254C (en)
NO (1) NO137500C (en)
PL (1) PL84891B1 (en)
SE (1) SE399702B (en)
ZA (1) ZA724512B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2267709A (en) * 1992-06-11 1993-12-15 Merck & Co Inc Novel process for the preparation of alpha-aminoacylanilides

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57182525U (en) * 1981-05-15 1982-11-19
JPH01128053U (en) * 1988-02-24 1989-08-31
JP2514855B2 (en) * 1990-08-08 1996-07-10 キッセイ薬品工業株式会社 Acid addition salts of optically active alanine anilide derivatives
EP2995303A1 (en) 2009-07-10 2016-03-16 President and Fellows of Harvard College Permanently charged sodium and calcium channel blockers as anti-inflammatory agents
DE102012210082A1 (en) * 2012-06-15 2013-12-19 Hilti Aktiengesellschaft Machine tool and control method
KR20180069782A (en) 2015-08-03 2018-06-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Charge ion channel blocker and how to use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CA3129131A1 (en) 2019-03-11 2020-09-17 Bridget Mccarthy Cole Charged ion channel blockers and methods for use
AU2020234961A1 (en) 2019-03-11 2021-09-30 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
KR20210145164A (en) 2019-03-11 2021-12-01 녹시온 테라퓨틱스 인코포레이티드 Ester Substituted Ion Channel Blockers and Methods of Use
US10842798B1 (en) 2019-11-06 2020-11-24 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
EP4054586A4 (en) 2019-11-06 2023-11-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
KR20230022830A (en) 2020-03-11 2023-02-16 녹시온 테라퓨틱스 인코포레이티드 Charged ion channel blockers and methods of use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2267709A (en) * 1992-06-11 1993-12-15 Merck & Co Inc Novel process for the preparation of alpha-aminoacylanilides
US5550288A (en) * 1992-06-11 1996-08-27 Merck & Co., Inc. Process for the preparation of α-aminoacylanilides

Also Published As

Publication number Publication date
AU476000B2 (en) 1976-09-09
AR193748A1 (en) 1973-05-22
SU441704A3 (en) 1974-08-30
DD101389A5 (en) 1973-11-05
BR7205069D0 (en) 1973-07-17
IE36607L (en) 1973-01-28
DE2235745A1 (en) 1973-02-22
NO137500C (en) 1978-03-08
AT317185B (en) 1974-08-12
DK142843C (en) 1981-08-31
CA982148A (en) 1976-01-20
FR2147277B1 (en) 1976-04-16
AU4488672A (en) 1974-01-31
IE36607B1 (en) 1976-12-08
FR2147277A1 (en) 1973-03-09
JPS565220B1 (en) 1981-02-04
PL84891B1 (en) 1976-04-30
NL176254C (en) 1985-03-18
DE2235745B2 (en) 1976-08-19
NL176254B (en) 1984-10-16
NL7210418A (en) 1973-01-30
FI55492C (en) 1979-08-10
NO137500B (en) 1977-11-28
BE786875A (en) 1973-01-29
ZA724512B (en) 1973-08-29
CS171171B2 (en) 1976-10-29
FI55492B (en) 1979-04-30
HU163818B (en) 1973-11-28
ES404739A1 (en) 1975-07-16
DK142843B (en) 1981-02-09
CH574397A5 (en) 1976-04-15
SE399702B (en) 1978-02-27

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Legal Events

Date Code Title Description
PS Patent sealed
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
746B Proceeding under section 46(3) patents act 1977
746D Case decided by the comptroller (sect. 46(3)/1977)
PE20 Patent expired after termination of 20 years