GB1333524A - Penicilloic acid derivatives - Google Patents

Penicilloic acid derivatives

Info

Publication number
GB1333524A
GB1333524A GB1135272A GB1135272A GB1333524A GB 1333524 A GB1333524 A GB 1333524A GB 1135272 A GB1135272 A GB 1135272A GB 1135272 A GB1135272 A GB 1135272A GB 1333524 A GB1333524 A GB 1333524A
Authority
GB
United Kingdom
Prior art keywords
acid derivatives
salts
formula
penicilloic acid
march
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1135272A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB1333524A publication Critical patent/GB1333524A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1333524 Penicilloic acid derivatives F HOFFMANN-LA ROCHE & CO AG 10 March 1972 [11 March 1971] 11352/72 Heading C2C Novel penicilloic acid derivatives of the Formula I wherein R is phenyl or 1,4-cyclohexadienyl and n is 1 to 5 and salts thereof, are prepared by reacting compounds of Formula II above with amino acids of the formula and, if desired, converting the reaction products into salts. Pharmaceutical compositions, suitable for oral or parenteral administration contain the above novel compounds or salts thereof and compatible pharmaceutical carriers. The compounds inhibit allergic reactions produced by the administration of penicillins.
GB1135272A 1971-03-11 1972-03-10 Penicilloic acid derivatives Expired GB1333524A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH355871 1971-03-11

Publications (1)

Publication Number Publication Date
GB1333524A true GB1333524A (en) 1973-10-10

Family

ID=4258572

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1135272A Expired GB1333524A (en) 1971-03-11 1972-03-10 Penicilloic acid derivatives
GB1135172A Expired GB1322149A (en) 1971-03-11 1972-03-10 Pharmaceutical compositions

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1135172A Expired GB1322149A (en) 1971-03-11 1972-03-10 Pharmaceutical compositions

Country Status (21)

Country Link
AT (2) AT312802B (en)
AU (1) AU461136B2 (en)
BE (2) BE780471A (en)
CA (1) CA972759A (en)
CH (1) CH546783A (en)
DE (2) DE2211419A1 (en)
DK (1) DK136977B (en)
ES (2) ES400623A1 (en)
FI (1) FI52345C (en)
FR (2) FR2128823B1 (en)
GB (2) GB1333524A (en)
HK (1) HK14676A (en)
HU (2) HU165203B (en)
IE (2) IE36203B1 (en)
IL (2) IL38864A (en)
NL (2) NL7202771A (en)
NO (1) NO138142C (en)
PH (2) PH12264A (en)
SE (3) SE406198B (en)
YU (1) YU35011B (en)
ZA (2) ZA721364B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316882A (en) * 1978-04-20 1982-02-23 Levine Bernard B Compositions for testing to predict and/or diagnose allergy to penicillins
CA1209477A (en) * 1981-03-26 1986-08-12 Bruce E. Haeger Composition of matter comprising a lyophilized preparation of a penicillin derivative

Also Published As

Publication number Publication date
IE36203B1 (en) 1976-09-15
BE780471A (en) 1972-09-11
AU461136B2 (en) 1975-04-30
ZA721364B (en) 1972-11-29
GB1322149A (en) 1973-07-04
FR2128823B1 (en) 1975-04-25
YU62572A (en) 1979-12-31
IL38865A (en) 1975-08-31
AU3957172A (en) 1973-09-06
HK14676A (en) 1976-03-26
NL7202771A (en) 1972-09-13
SE7513807L (en) 1975-12-08
AT331389B (en) 1976-08-25
SE406198B (en) 1979-01-29
IL38865A0 (en) 1972-05-30
FR2128823A1 (en) 1972-10-20
YU35011B (en) 1980-06-30
PH12264A (en) 1978-12-12
DK136977B (en) 1977-12-27
CH546783A (en) 1974-03-15
DE2211420A1 (en) 1972-09-21
ATA188672A (en) 1975-11-15
IL38864A0 (en) 1972-05-30
CA972759A (en) 1975-08-12
NO138142C (en) 1978-07-12
DK136977C (en) 1978-06-05
FR2128824A1 (en) 1972-10-20
FR2128824B1 (en) 1975-06-13
BE780472A (en) 1972-09-11
ES400624A1 (en) 1975-02-01
HU166712B (en) 1975-05-28
NO138142B (en) 1978-04-03
FI52345B (en) 1977-05-02
IE36204L (en) 1972-09-11
HU165203B (en) 1974-07-27
DE2211419A1 (en) 1972-09-21
IL38864A (en) 1975-08-31
FI52345C (en) 1977-08-10
SE7514031L (en) 1975-12-11
AT312802B (en) 1974-01-25
ZA721363B (en) 1972-11-29
IE36204B1 (en) 1976-09-15
PH9295A (en) 1975-08-15
IE36203L (en) 1972-09-11
NL7202772A (en) 1972-09-13
ES400623A1 (en) 1975-02-01

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee