GB1421589A - Salicylanilide derivatives - Google Patents

Salicylanilide derivatives

Info

Publication number
GB1421589A
GB1421589A GB985473A GB985473A GB1421589A GB 1421589 A GB1421589 A GB 1421589A GB 985473 A GB985473 A GB 985473A GB 985473 A GB985473 A GB 985473A GB 1421589 A GB1421589 A GB 1421589A
Authority
GB
United Kingdom
Prior art keywords
salicylanilides
aris
comptroller
dichlorophenyl
chlorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB985473A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of GB1421589A publication Critical patent/GB1421589A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06—Preparation of nitro compounds
    • C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
    • C07C65/05—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring o-Hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
    • C07C65/105—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)

Abstract

1421589 Salicylanilides JANSSEN PHARMACEUTICA NV 28 Feb 1973 [7 March 1972 31 Jan 1973] 9854/73 Heading C2C Novel salicylanilides of the formula wherein R is H or Cl; R 1 is I or Cl; R 2 is I or Cl; R 3 is H or Cl; Y is CH 2 or CO; and Aris chlorophenyl or dichlorophenyl; provided that when R is H, then at least one of R 1 or R 2 is I, are prepared by reacting the appropriate salicyclic acid halides with the corresponding anilines. Pharmaceutical or veterinary compositions, suitable for oral administration, contain the above salicylanilides with ingestible carriers therefor. The compounds possess flukicidal activity. Reference has been directed by the Comptroller to Specification 1,183,641.
GB985473A 1972-03-07 1973-02-28 Salicylanilide derivatives Expired GB1421589A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23237472A 1972-03-07 1972-03-07
US32817073A 1973-01-31 1973-01-31

Publications (1)

Publication Number Publication Date
GB1421589A true GB1421589A (en) 1976-01-21

Family

ID=26925928

Family Applications (1)

Application Number Title Priority Date Filing Date
GB985473A Expired GB1421589A (en) 1972-03-07 1973-02-28 Salicylanilide derivatives

Country Status (10)

Country Link
JP (1) JPS4899153A (en)
ES (1) ES412380A1 (en)
GB (1) GB1421589A (en)
HU (1) HU166581B (en)
IL (1) IL41714A0 (en)
IT (1) IT984259B (en)
LU (1) LU67158A1 (en)
NL (1) NL7303067A (en)
OA (1) OA04342A (en)
PH (1) PH9618A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104677A1 (en) * 1982-09-17 1984-04-04 Janssen Pharmaceutica N.V. Chemical sterilisation of insects with salicyl anilides
US9949988B2 (en) 2014-09-12 2018-04-24 Antibiotx A/S Antibacterial use of halogenated salicylanilides
US10463680B2 (en) 2015-05-29 2019-11-05 UNION therapeutics A/S Halogenated salicylanilides for treating clostridium infections
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57159261A (en) * 1981-03-26 1982-10-01 Yoshiaki Kawada Connnecting method for stainless steel pipes

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0104677A1 (en) * 1982-09-17 1984-04-04 Janssen Pharmaceutica N.V. Chemical sterilisation of insects with salicyl anilides
US9949988B2 (en) 2014-09-12 2018-04-24 Antibiotx A/S Antibacterial use of halogenated salicylanilides
US10758553B2 (en) 2014-09-12 2020-09-01 UNION therapeutics A/S Antibacterial use of halogenated salicylanilides
US11285164B2 (en) 2014-09-12 2022-03-29 UNION therapeutics A/S Antibacterial use of halogenated salicylanilides
US11324761B2 (en) 2014-09-12 2022-05-10 UNION therapeutics A/S Antibacterial use of halogenated salicylanilides
US11331327B2 (en) 2014-09-12 2022-05-17 UNION therapeutics A/S Antibacterial use of halogenated salicylanilides
US10463680B2 (en) 2015-05-29 2019-11-05 UNION therapeutics A/S Halogenated salicylanilides for treating clostridium infections
US10857164B2 (en) 2015-05-29 2020-12-08 UNION therapeutics A/S Halogenated salicylanilides for treating Clostridium infections
US11529361B2 (en) 2015-05-29 2022-12-20 UNION therapeutics A/S Halogenated salicylanilides for treating Clostridium infections
US11419834B2 (en) 2019-02-25 2022-08-23 Rhode Island Hospital Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide

Also Published As

Publication number Publication date
LU67158A1 (en) 1973-05-22
PH9618A (en) 1976-01-20
OA04342A (en) 1980-01-31
NL7303067A (en) 1973-09-11
IL41714A0 (en) 1973-05-31
JPS4899153A (en) 1973-12-15
ES412380A1 (en) 1976-05-01
HU166581B (en) 1975-04-28
IT984259B (en) 1974-11-20

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Legal Events

Date Code Title Description
CSNS Application of which complete specification have been accepted and published, but patent is not sealed