GB1361886A - N-formyl-dl-homocysteine thiolactone and its use as a drug - Google Patents
N-formyl-dl-homocysteine thiolactone and its use as a drugInfo
- Publication number
- GB1361886A GB1361886A GB1263372A GB1263372A GB1361886A GB 1361886 A GB1361886 A GB 1361886A GB 1263372 A GB1263372 A GB 1263372A GB 1263372 A GB1263372 A GB 1263372A GB 1361886 A GB1361886 A GB 1361886A
- Authority
- GB
- United Kingdom
- Prior art keywords
- homocysteine thiolactone
- formyl
- drug
- march
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/36—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1361886 N-Formyl-DL-homocysteine thiolactone FWEAU SA 17 March 1972 [18 March 1971] 12633/72 Heading C2C The novel title compound is prepared by reacting DL-homocysteine thiolactone hydrochloride with a mixture of acetic anhydride and formic acid. Pharmaceutical compositions, suitable for oral administration, contain the above compound together with suitable excipients. The compound possesses hepatoprotective properties and is used in the treatment of hepatitis and cirrhosis of the liver.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7109517A FR2129877B1 (en) | 1971-03-18 | 1971-03-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1361886A true GB1361886A (en) | 1974-07-30 |
Family
ID=9073740
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1263372A Expired GB1361886A (en) | 1971-03-18 | 1972-03-17 | N-formyl-dl-homocysteine thiolactone and its use as a drug |
Country Status (7)
Country | Link |
---|---|
BE (1) | BE780572A (en) |
CH (1) | CH545806A (en) |
DE (1) | DE2213028B2 (en) |
ES (1) | ES400893A1 (en) |
FR (1) | FR2129877B1 (en) |
GB (1) | GB1361886A (en) |
NL (1) | NL7203597A (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT326111B (en) * | 1973-05-15 | 1975-11-25 | Degussa | PROCESS FOR THE PREPARATION OF NEW N-ALCOXYBENZOYLAMINO ACIDS, THEIR C1-C5-ALKESTERS AND ASSOCIATED THIOLACTONES AND THEIR SALTS |
US4055653A (en) | 1973-05-15 | 1977-10-25 | Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler | Sulfur containing trialkoxybenzoylamino carboxylic acids |
FR2265355B1 (en) * | 1974-03-28 | 1977-11-04 | Blum Jean | |
FR2502153A1 (en) * | 1981-03-19 | 1982-09-24 | Rech Pharmaceutiq Medicale | (2-OXO-3-TETRAHYDROTHIENYLCARBAMOYL) -ALKYLTHIO) ACETIC ACIDS, THEIR SALTS AND ESTERS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
IT1215238B (en) * | 1985-02-22 | 1990-01-31 | Chiesi Farma Spa | DERIVATIVES OF HOMOCYSTEIN TIOLACTONE, THEIR PREPARATION PROCEDURE AND PHARMACEUTICAL FORMULATIONS |
ES2061398B1 (en) * | 1993-03-02 | 1996-02-16 | Prodesfarma Sa | PROCEDURE FOR OBTAINING N-ACETYL HOMOCISTEINE THYOLACTONE FROM DL-HOMOSCISTINE BY ELECTROCHEMICAL METHODS. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH59A (en) * | 1889-01-08 | Grusonwerk Ag | Firing pin hammer for rear loading guns | |
DE1023561B (en) * | 1957-04-05 | 1958-01-30 | Degussa | Skin and hair care products |
-
1971
- 1971-03-18 FR FR7109517A patent/FR2129877B1/fr not_active Expired
-
1972
- 1972-03-13 BE BE780572A patent/BE780572A/en unknown
- 1972-03-14 DE DE19722213028 patent/DE2213028B2/en not_active Withdrawn
- 1972-03-16 CH CH390172A patent/CH545806A/xx not_active IP Right Cessation
- 1972-03-17 GB GB1263372A patent/GB1361886A/en not_active Expired
- 1972-03-17 ES ES400893A patent/ES400893A1/en not_active Expired
- 1972-03-17 NL NL7203597A patent/NL7203597A/xx not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CH545806A (en) | 1974-02-15 |
BE780572A (en) | 1972-07-03 |
FR2129877A1 (en) | 1972-11-03 |
DE2213028B2 (en) | 1977-08-18 |
NL7203597A (en) | 1972-09-20 |
FR2129877B1 (en) | 1974-08-02 |
DE2213028A1 (en) | 1972-09-28 |
ES400893A1 (en) | 1975-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
435 | Patent endorsed 'licences of right' on the date specified (sect. 35/1949) | ||
PCNP | Patent ceased through non-payment of renewal fee | ||
PCPE | Delete 'patent ceased' from journal |
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