SE528407C2 - Borföreningar användbara vid BNCT - Google Patents

Borföreningar användbara vid BNCT

Info

Publication number
SE528407C2
SE528407C2 SE0501903A SE0501903A SE528407C2 SE 528407 C2 SE528407 C2 SE 528407C2 SE 0501903 A SE0501903 A SE 0501903A SE 0501903 A SE0501903 A SE 0501903A SE 528407 C2 SE528407 C2 SE 528407C2
Authority
SE
Sweden
Prior art keywords
tumor
compound
formula
boron
therapy
Prior art date
Application number
SE0501903A
Other languages
English (en)
Swedish (sv)
Other versions
SE0501903L (sv
Inventor
Lars-Inge Olsson
Arne Eek
Erwan Arzel
Original Assignee
Hammercap Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hammercap Ab filed Critical Hammercap Ab
Priority to SE0501903A priority Critical patent/SE528407C2/sv
Priority to PCT/SE2006/000952 priority patent/WO2007021234A1/en
Priority to RU2008110472/04A priority patent/RU2423368C2/ru
Priority to US11/990,634 priority patent/US8183247B2/en
Priority to JP2008526905A priority patent/JP5053277B2/ja
Priority to EP06769619.5A priority patent/EP1915381B1/en
Priority to CN2006800301784A priority patent/CN101268085B/zh
Priority to TW095130337A priority patent/TWI376381B/zh
Publication of SE0501903L publication Critical patent/SE0501903L/xx
Publication of SE528407C2 publication Critical patent/SE528407C2/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/027—Organoboranes and organoborohydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Radiation-Therapy Devices (AREA)
SE0501903A 2005-08-19 2005-08-30 Borföreningar användbara vid BNCT SE528407C2 (sv)

Priority Applications (8)

Application Number Priority Date Filing Date Title
SE0501903A SE528407C2 (sv) 2005-08-19 2005-08-30 Borföreningar användbara vid BNCT
PCT/SE2006/000952 WO2007021234A1 (en) 2005-08-19 2006-08-17 Boron compounds useful in bnct
RU2008110472/04A RU2423368C2 (ru) 2005-08-19 2006-08-17 Соединения бора, пригодные при борнейтронозахватной терапии
US11/990,634 US8183247B2 (en) 2005-08-19 2006-08-17 Boron compounds useful in BNCT
JP2008526905A JP5053277B2 (ja) 2005-08-19 2006-08-17 Ｂｎｃｔに有用なホウ素化合物
EP06769619.5A EP1915381B1 (en) 2005-08-19 2006-08-17 Boron compounds useful in bnct
CN2006800301784A CN101268085B (zh) 2005-08-19 2006-08-17 用于硼中子俘获治疗的硼化合物
TW095130337A TWI376381B (en) 2005-08-19 2006-08-18 Boron compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0501847 2005-08-19
SE0501903A SE528407C2 (sv) 2005-08-19 2005-08-30 Borföreningar användbara vid BNCT

Publications (2)

Publication Number Publication Date
SE0501903L SE0501903L (sv) 2006-11-07
SE528407C2 true SE528407C2 (sv) 2006-11-07

Family

ID=37310298

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0501903A SE528407C2 (sv) 2005-08-19 2005-08-30 Borföreningar användbara vid BNCT

Country Status (8)

Country Link
US (1) US8183247B2 (https=)
EP (1) EP1915381B1 (https=)
JP (1) JP5053277B2 (https=)
CN (1) CN101268085B (https=)
RU (1) RU2423368C2 (https=)
SE (1) SE528407C2 (https=)
TW (1) TWI376381B (https=)
WO (1) WO2007021234A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007026701A1 (de) * 2007-06-01 2008-12-04 Universität Leipzig Neue chemische Verbindungen, deren Herstellung und deren Verwendung
CN101713740B (zh) * 2009-12-31 2012-05-02 中国原子能科学研究院 分光光度测量生物样品中bnct药物里硼含量的方法
CN104151339B (zh) * 2013-05-17 2017-05-03 中国科学院近代物理研究所 含硼吖啶衍生物、其制备方法和应用
JP6360113B2 (ja) * 2016-07-28 2018-07-18 ステラファーマ株式会社 ホウ素含有化合物
KR101903693B1 (ko) * 2016-11-28 2018-10-04 가천대학교 산학협력단 BSH 합성을 위한 티오피롤리딘을 이용한 Na2[B12H12] 반응
JP7154528B2 (ja) * 2017-08-25 2022-10-18 国立大学法人東京工業大学 ホウ素含有葉酸誘導体
WO2020180390A1 (en) * 2019-03-04 2020-09-10 TAE Life Sciences Borylated amino acid compositions for use in boron neutron capture therapy and methods thereof
CN112358494B (zh) * 2020-04-09 2021-09-28 南京大学 一种基于吖啶的碳硼烷衍生物及其在生物显影中的应用
CN112442095B (zh) * 2020-12-01 2022-07-22 上海科黛生物科技有限公司 一种维生素b12的精制方法及所得产品的应用
CN112979686B (zh) * 2021-02-08 2022-04-08 北京大学 一种新型硼携带剂、制备方法及其药物制剂
CN116874515B (zh) * 2023-05-10 2025-03-14 重庆高硼生物科技有限公司 一种氨基酸-bsh靶向杂合体化合物及其制备方法和应用
WO2025165163A1 (ko) * 2024-01-31 2025-08-07 (주)클리켐바이오 붕소중성자포획치료용 알부민 나노플랫폼 및 이를 포함하는 붕소중성자포획치료용 조성물

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272250A (en) 1992-07-10 1993-12-21 Spielvogel Bernard F Boronated phosphoramidate compounds
US6180766B1 (en) 1993-12-02 2001-01-30 Raymond F. Schinazi Nucleosides and oligonucleotides containing boron clusters
CN1124821A (zh) * 1994-02-14 1996-06-19 肖冠英 同步齿带半潜传动全贯流水电机组
US5630786A (en) * 1994-06-27 1997-05-20 Ionix Corporation Boron neutron capture enhancement of fast neutron therapy
JP2685128B2 (ja) * 1995-07-21 1997-12-03 東北大学長 カルボラン含有ガドリニウム−ｄｔｐａ錯体、その中間体、およびこれらの製造方法
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
DE19905094C1 (de) 1999-02-01 2000-10-12 Schering Ag Gadolinium (III)-Komplexe sowie ihre Verwendung für Zweischritt Strahlentherapieformen und diese enthaltende pharmazeutische Mittel
JP2001233883A (ja) * 2000-02-22 2001-08-28 Okayama Pref Gov Shin Gijutsu Shinko Zaidan カゴ状ホウ素化合物担持ポルフィリン錯体
EP1364954A4 (en) 2001-02-09 2009-10-28 Hiroyuki Kagechika Dicarba closo DODECARBORANDERIVATE
CA2555597C (en) * 2004-02-13 2016-06-14 The University Of British Columbia Radiolabeled compounds and compositions, their precursors and methods for their production
JP2005343858A (ja) * 2004-06-07 2005-12-15 Mebiopharm Co Ltd ホウ素イオンクラスター脂質及びこれを用いたリポソーム
JP2006096870A (ja) * 2004-09-29 2006-04-13 Stella Chemifa Corp ホウ素含有化合物

Also Published As

Publication number Publication date
JP2009504732A (ja) 2009-02-05
CN101268085A (zh) 2008-09-17
TWI376381B (en) 2012-11-11
RU2008110472A (ru) 2009-09-27
JP5053277B2 (ja) 2012-10-17
EP1915381B1 (en) 2013-04-10
US20090227539A1 (en) 2009-09-10
EP1915381A1 (en) 2008-04-30
EP1915381A4 (en) 2011-02-09
SE0501903L (sv) 2006-11-07
CN101268085B (zh) 2012-06-20
RU2423368C2 (ru) 2011-07-10
US8183247B2 (en) 2012-05-22
WO2007021234A1 (en) 2007-02-22
TW200740833A (en) 2007-11-01

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