SE467875B - Foerfarande foer framstaellning av vinblastin och vinkristin. - Google Patents

Foerfarande foer framstaellning av vinblastin och vinkristin.

Info

Publication number
SE467875B
SE467875B SE8802813A SE8802813A SE467875B SE 467875 B SE467875 B SE 467875B SE 8802813 A SE8802813 A SE 8802813A SE 8802813 A SE8802813 A SE 8802813A SE 467875 B SE467875 B SE 467875B
Authority
SE
Sweden
Prior art keywords
formula
alkyl
enamine
alk
aryl
Prior art date
Application number
SE8802813A
Other languages
English (en)
Swedish (sv)
Other versions
SE8802813L (sv
SE8802813D0 (sv
Inventor
J P Kutney
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of SE8802813D0 publication Critical patent/SE8802813D0/xx
Publication of SE8802813L publication Critical patent/SE8802813L/xx
Publication of SE467875B publication Critical patent/SE467875B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE8802813A 1987-08-06 1988-08-03 Foerfarande foer framstaellning av vinblastin och vinkristin. SE467875B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000543832A CA1341262C (en) 1987-08-06 1987-08-06 A new process of the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine

Publications (3)

Publication Number Publication Date
SE8802813D0 SE8802813D0 (sv) 1988-08-03
SE8802813L SE8802813L (sv) 1989-02-07
SE467875B true SE467875B (sv) 1992-09-28

Family

ID=4136214

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8802813A SE467875B (sv) 1987-08-06 1988-08-03 Foerfarande foer framstaellning av vinblastin och vinkristin.

Country Status (12)

Country Link
JP (1) JPH0613532B2 (it)
AU (1) AU617342B2 (it)
BE (1) BE1003228A4 (it)
CA (1) CA1341262C (it)
CH (1) CH676711A5 (it)
DE (1) DE3826412A1 (it)
GB (1) GB2215331B (it)
HU (1) HU208829B (it)
IT (1) IT1227155B (it)
NL (1) NL8801966A (it)
SE (1) SE467875B (it)
ZA (1) ZA885765B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047528A (en) * 1987-01-22 1991-09-10 University Of Bristish Columbia Process of synthesis of vinblastine and vincristine
USRE37449E1 (en) 1987-02-06 2001-11-13 University Of British Columbia Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
US5432279A (en) * 1989-03-04 1995-07-11 Mitsui Petrochemical Industries, Inc. Process for the preparation of binary indole alkaloids
US5367081A (en) * 1990-11-30 1994-11-22 Fujirebio Inc. 1,4-dihydropyridine derivatives
JP3010151U (ja) * 1994-04-26 1995-04-25 スミ子 片山 切込みのついた筒形食器収納ケース。
FR2779146B1 (fr) * 1998-06-02 2002-01-18 Roowin Nouveaux derives de vinca-alcaloides et procedes de preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
HU195513B (en) * 1984-10-16 1988-05-30 Richter Gedeon Vegyeszet Process for producing stable solutions of alkaloides with bis-indole skeleton
WO1986005491A1 (en) * 1985-03-12 1986-09-25 The University Of Vermont And State Agricultural C Synthesis of vinblastine and vincristine type compounds
CA1341261C (en) * 1987-01-22 2001-06-26 James P. Kutney Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine

Also Published As

Publication number Publication date
GB2215331A (en) 1989-09-20
CH676711A5 (it) 1991-02-28
IT1227155B (it) 1991-03-19
AU2051288A (en) 1989-02-09
DE3826412A1 (de) 1989-02-16
JPH0613532B2 (ja) 1994-02-23
ZA885765B (en) 1989-09-27
CA1341262C (en) 2001-06-26
JPH01151590A (ja) 1989-06-14
SE8802813L (sv) 1989-02-07
HUT50351A (en) 1990-01-29
IT8821678A0 (it) 1988-08-05
AU617342B2 (en) 1991-11-28
NL8801966A (nl) 1989-03-01
BE1003228A4 (fr) 1992-02-04
GB8818765D0 (en) 1988-09-07
GB2215331B (en) 1992-01-02
SE8802813D0 (sv) 1988-08-03
HU208829B (en) 1994-01-28

Similar Documents

Publication Publication Date Title
AU2003222785B2 (en) Fredericamycin derivatives
US4279817A (en) Method for producing dimer alkaloids
Kanne et al. Synthesis and biological characterization of pyridohomotropanes. Structure-activity relationships of conformationally restricted nicotinoids
NO179748B (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive bis-(1H-indol-3-yl)-maleinimidderivater
CZ244893A3 (en) Novel perhydroisoindole derivatives, and process for preparing thereof
DK141511B (da) Analogifremgangsmåde til fremstilling af derivater af vindblastin, leurosidin eller leurocristin.
SE467875B (sv) Foerfarande foer framstaellning av vinblastin och vinkristin.
Mohr et al. Tilivalline, a new pyrrolo [2, 1-c][1, 4] benzodiazepine metabolite from klebsiella
US5047528A (en) Process of synthesis of vinblastine and vincristine
DE3801450C2 (de) Verfahren für die Herstellung von Dimeralkaloidverbindungen, insbesondere von 3', 4'-Dihydrovinblastin, Vinblastin und Vincristin
US4191688A (en) Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
Lamberton et al. Alkaloids of Peripentadenia mearsii. I. Isolation, Structural Determination, and Synthesis of Peripentadenine
Evnin et al. Synthesis and cycloaddition reactions of dehydrohydantoins
USRE37449E1 (en) Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
US3583992A (en) 1-methyl-d-lysergic acid-dihydroxy-alkyl-amides
Takahashi et al. Photochemistry of diazonium salts. Syntheses of 2, 4-difluoroimidazole-5-carboxylic acid and related compounds
FI95260B (fi) 7-(difenyylimetyyli)oksi-9a-metoksimitosaani sekä sen valmistus
USRE30561E (en) Vinca alkaloid intermediates
Simonov et al. Nucleophilic substitution and cyclization reactions involving quaternized 3-dimethylaminomethyl derivatives of 3, 4-bis (indol-l-yl) maleimide and 3-(indol-l-yl)-4-(indolin-l-yl) maleimide
Manna et al. Synthesis of the alkaloid nauclefidin
FI75161B (fi) Foerfarande foer framstaellning av alkoxiapovinkaminsyraestrar och mellanprodukt foer anvaendning vid foerfarandet.
Daidone et al. Studies on the synthesis of heterocyclic compounds. Part IV. Further investigation of the pschorr reaction with some pyrazole derivatives
EP4345102A1 (en) Improved synthesis of otviciclib
HU181874B (en) Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
GB2086378A (en) Process for the Preparation of Cytostatic Compounds

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8802813-9

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8802813-9

Format of ref document f/p: F