AU617342B2 - Process for the synthesis of dimer alkaloid compounds - Google Patents

Process for the synthesis of dimer alkaloid compounds Download PDF

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Publication number
AU617342B2
AU617342B2 AU20512/88A AU2051288A AU617342B2 AU 617342 B2 AU617342 B2 AU 617342B2 AU 20512/88 A AU20512/88 A AU 20512/88A AU 2051288 A AU2051288 A AU 2051288A AU 617342 B2 AU617342 B2 AU 617342B2
Authority
AU
Australia
Prior art keywords
process according
alkyl
formula
enamine
alk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU20512/88A
Other languages
English (en)
Other versions
AU2051288A (en
Inventor
Camille A. Boulet
Lewis S. L. Choi
James P. Kutney
Michael Mchugh
Jun Nakano
Hiroki Tsukamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of AU2051288A publication Critical patent/AU2051288A/en
Application granted granted Critical
Publication of AU617342B2 publication Critical patent/AU617342B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU20512/88A 1987-01-22 1988-08-05 Process for the synthesis of dimer alkaloid compounds Ceased AU617342B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA527897 1987-01-22
US011810 1987-02-06
CA543832 1987-08-06
CA000543832A CA1341262C (en) 1987-08-06 1987-08-06 A new process of the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU10668/88A Division AU1066888A (en) 1987-01-22 1988-01-21 Process for the synthesis of vinblastine and vincristine

Publications (2)

Publication Number Publication Date
AU2051288A AU2051288A (en) 1989-02-09
AU617342B2 true AU617342B2 (en) 1991-11-28

Family

ID=4136214

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20512/88A Ceased AU617342B2 (en) 1987-01-22 1988-08-05 Process for the synthesis of dimer alkaloid compounds

Country Status (12)

Country Link
JP (1) JPH0613532B2 (it)
AU (1) AU617342B2 (it)
BE (1) BE1003228A4 (it)
CA (1) CA1341262C (it)
CH (1) CH676711A5 (it)
DE (1) DE3826412A1 (it)
GB (1) GB2215331B (it)
HU (1) HU208829B (it)
IT (1) IT1227155B (it)
NL (1) NL8801966A (it)
SE (1) SE467875B (it)
ZA (1) ZA885765B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047528A (en) * 1987-01-22 1991-09-10 University Of Bristish Columbia Process of synthesis of vinblastine and vincristine
USRE37449E1 (en) 1987-02-06 2001-11-13 University Of British Columbia Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
US5432279A (en) * 1989-03-04 1995-07-11 Mitsui Petrochemical Industries, Inc. Process for the preparation of binary indole alkaloids
ATE182140T1 (de) * 1990-11-30 1999-07-15 Fujirebio Kk Optisch aktive 1,4-dihydropyridinderivate sowie verfahren zu ihrer herstellung
JP3010151U (ja) * 1994-04-26 1995-04-25 スミ子 片山 切込みのついた筒形食器収納ケース。
FR2779146B1 (fr) * 1998-06-02 2002-01-18 Roowin Nouveaux derives de vinca-alcaloides et procedes de preparation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU580342B2 (en) * 1984-10-16 1989-01-12 Richter Gedeon Vegyeszeti Gyar Rt. Metal complexes of bis-indole compounds and aqueous pharmaceutical compositions containing them
AU590873B2 (en) * 1985-03-12 1989-11-23 University Of Vermont And State Agricultural College, The Synthesis of vinblastine and vincristine type compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
CA1341261C (en) * 1987-01-22 2001-06-26 James P. Kutney Process for the synthesis of 3',4'-anhydrovinblastine, vinblastine and vincristine

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU580342B2 (en) * 1984-10-16 1989-01-12 Richter Gedeon Vegyeszeti Gyar Rt. Metal complexes of bis-indole compounds and aqueous pharmaceutical compositions containing them
AU590873B2 (en) * 1985-03-12 1989-11-23 University Of Vermont And State Agricultural College, The Synthesis of vinblastine and vincristine type compounds

Also Published As

Publication number Publication date
SE8802813D0 (sv) 1988-08-03
ZA885765B (en) 1989-09-27
DE3826412A1 (de) 1989-02-16
SE8802813L (sv) 1989-02-07
CA1341262C (en) 2001-06-26
GB8818765D0 (en) 1988-09-07
HU208829B (en) 1994-01-28
SE467875B (sv) 1992-09-28
GB2215331B (en) 1992-01-02
CH676711A5 (it) 1991-02-28
HUT50351A (en) 1990-01-29
AU2051288A (en) 1989-02-09
BE1003228A4 (fr) 1992-02-04
JPH0613532B2 (ja) 1994-02-23
GB2215331A (en) 1989-09-20
JPH01151590A (ja) 1989-06-14
IT8821678A0 (it) 1988-08-05
NL8801966A (nl) 1989-03-01
IT1227155B (it) 1991-03-19

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired