SE465269B - 1,4-dihydropyridinderivat och salter daerav, foerfarande foer deras framstaellning och farmacevtiska kompositioner innehaallande dessa - Google Patents
1,4-dihydropyridinderivat och salter daerav, foerfarande foer deras framstaellning och farmacevtiska kompositioner innehaallande dessaInfo
- Publication number
- SE465269B SE465269B SE8503111A SE8503111A SE465269B SE 465269 B SE465269 B SE 465269B SE 8503111 A SE8503111 A SE 8503111A SE 8503111 A SE8503111 A SE 8503111A SE 465269 B SE465269 B SE 465269B
- Authority
- SE
- Sweden
- Prior art keywords
- group
- ethyl
- dihydropyridine
- salt
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/32—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/48—Aldehydo radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59130645A JPS6110576A (ja) | 1984-06-25 | 1984-06-25 | 新規な1,4―ジヒドロピリジン誘導体およびその塩、それらの製造法並びにそれらを含有する循環障害治療剤 |
JP60000497A JPH06747B2 (ja) | 1985-01-07 | 1985-01-07 | ピリジン誘導体およびその製造法 |
JP60037130A JPH068294B2 (ja) | 1985-02-26 | 1985-02-26 | 新規な1,4−ジヒドロピリジン誘導体およびその塩 |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8503111D0 SE8503111D0 (sv) | 1985-06-20 |
SE8503111L SE8503111L (sv) | 1985-12-26 |
SE465269B true SE465269B (sv) | 1991-08-19 |
Family
ID=27274484
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8503111A SE465269B (sv) | 1984-06-25 | 1985-06-20 | 1,4-dihydropyridinderivat och salter daerav, foerfarande foer deras framstaellning och farmacevtiska kompositioner innehaallande dessa |
Country Status (10)
Country | Link |
---|---|
US (1) | US4713387A (da) |
BE (1) | BE902739A (da) |
CH (1) | CH666033A5 (da) |
DE (1) | DE3522579C2 (da) |
DK (1) | DK170642B1 (da) |
FR (1) | FR2566404B1 (da) |
GB (1) | GB2162513B (da) |
IT (1) | IT1181705B (da) |
NL (1) | NL8501826A (da) |
SE (1) | SE465269B (da) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8714013D0 (en) * | 1987-06-16 | 1987-07-22 | Ici Plc | (substituted-aralkyl)heterocyclic compounds |
JPH0725750B2 (ja) * | 1987-12-18 | 1995-03-22 | 富士レビオ株式会社 | 1,4‐ジヒドロピリジン誘導体 |
US5506219A (en) * | 1988-08-29 | 1996-04-09 | E. R. Squibb & Sons, Inc. | Pyridine anchors for HMG-CoA reductase inhibitors |
US5286869A (en) * | 1988-12-15 | 1994-02-15 | Fujirebio Kabushiki Kaisha | 1,4-dihydropyridine derivatives |
JPH03504014A (ja) * | 1989-02-17 | 1991-09-05 | インスティテュト オルガニチェスコゴ シンテザ アカデミイ ナウク ラトビイスコイ エスエスアール | 2‐(2,6‐ジメチル‐3,5‐ジエトキシカルボニル―1,4‐ジヒドロピリジン‐4‐カルボキサミド)エタンスルホン酸のアルカリ塩の調製方法 |
WO1997036898A1 (en) * | 1996-04-03 | 1997-10-09 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
AU706314B2 (en) * | 1996-04-03 | 1999-06-17 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US5883105A (en) * | 1996-04-03 | 1999-03-16 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
AU714851B2 (en) * | 1996-04-03 | 2000-01-13 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
CA2249605A1 (en) * | 1996-04-03 | 1997-10-09 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
JP2000507590A (ja) * | 1996-04-03 | 2000-06-20 | メルク エンド カンパニー インコーポレーテッド | ファルネシル―タンパク質トランスフェラーゼ阻害剤 |
US5854265A (en) * | 1996-04-03 | 1998-12-29 | Merck & Co., Inc. | Biheteroaryl inhibitors of farnesyl-protein transferase |
US6093737A (en) * | 1996-12-30 | 2000-07-25 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US5939439A (en) * | 1996-12-30 | 1999-08-17 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US6127390A (en) * | 1997-10-02 | 2000-10-03 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
US20030207876A1 (en) * | 2000-06-23 | 2003-11-06 | Banks Bernard Joseph | 3-Azabicyclo[3.1.0]hexane derivatives useful in therapy |
EP2868709A1 (en) * | 2013-10-29 | 2015-05-06 | DyStar Colours Distribution GmbH | Metal free acid dyes, process for the production thereof and their use |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
US4656181A (en) * | 1982-11-24 | 1987-04-07 | Cermol S.A. | Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same |
-
1985
- 1985-06-18 GB GB08515413A patent/GB2162513B/en not_active Expired
- 1985-06-20 SE SE8503111A patent/SE465269B/sv not_active IP Right Cessation
- 1985-06-21 US US06/747,305 patent/US4713387A/en not_active Expired - Fee Related
- 1985-06-24 CH CH2682/85A patent/CH666033A5/de not_active IP Right Cessation
- 1985-06-24 IT IT48267/85A patent/IT1181705B/it active
- 1985-06-24 DE DE3522579A patent/DE3522579C2/de not_active Expired - Fee Related
- 1985-06-24 DK DK284585A patent/DK170642B1/da not_active IP Right Cessation
- 1985-06-25 FR FR8509671A patent/FR2566404B1/fr not_active Expired
- 1985-06-25 NL NL8501826A patent/NL8501826A/nl not_active Application Discontinuation
- 1985-06-25 BE BE0/215255A patent/BE902739A/fr not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4713387A (en) | 1987-12-15 |
FR2566404A1 (fr) | 1985-12-27 |
GB8515413D0 (en) | 1985-07-17 |
DK170642B1 (da) | 1995-11-20 |
GB2162513A (en) | 1986-02-05 |
SE8503111L (sv) | 1985-12-26 |
DE3522579C2 (de) | 1995-10-12 |
BE902739A (fr) | 1985-12-30 |
DE3522579A1 (de) | 1986-01-02 |
FR2566404B1 (fr) | 1989-09-22 |
DK284585D0 (da) | 1985-06-24 |
GB2162513B (en) | 1988-01-20 |
CH666033A5 (de) | 1988-06-30 |
NL8501826A (nl) | 1986-01-16 |
SE8503111D0 (sv) | 1985-06-20 |
IT1181705B (it) | 1987-09-30 |
DK284585A (da) | 1985-12-26 |
IT8548267A0 (it) | 1985-06-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE465269B (sv) | 1,4-dihydropyridinderivat och salter daerav, foerfarande foer deras framstaellning och farmacevtiska kompositioner innehaallande dessa | |
US4704459A (en) | Process for producing 1-substituted aryl-1,4-dihydro-4-oxonaphthyridine derivatives, and processes for producing the intermediates | |
US20070244088A1 (en) | New Pyridine Analogues II | |
US20020137770A1 (en) | Piperidine derivatives | |
CA3085347A1 (en) | Pyrazole n-linked carbamoyl cyclohexyl acids as lpa antagonists | |
KR19990022327A (ko) | N-헤테로아릴-피리딘설폰아미드 유도체 및 이의 엔도텔린 길항 물질로서의 용도 | |
PT89477A (pt) | Processo para a preparacao de piridinas substituidas | |
JPH1029979A (ja) | 新規ピリジン誘導体 | |
CA2075673A1 (en) | (2-alkyl-3-pyridyl)methylpiperazine derivatives | |
US5149702A (en) | Cycloheptenopyridine derivatives, process for preparation thereof and antiulcer agents containing the same | |
EP0189771A3 (en) | (isoxazol-3-yl)arylmethanones, a process for their preparation and their use as medicaments | |
US5134151A (en) | 2-picolylamine derivatives | |
US4851535A (en) | Nicotinic acid derivatives | |
US4731370A (en) | Pyridyl ester containing 1,4-dihydropyridine derivatives and salts thereof and pharmaceutical composition containing the same | |
US6433167B1 (en) | Triazolo-1,4-diazepine compounds and medicinal composition containing the same | |
US4737506A (en) | Anti-arteriosclerotic pyridyl or imidazolyl derivatives of carbonyloxyalkyl hantzsch esters | |
JPS60208960A (ja) | 2,6−ジ置換−1,4−ジヒドロピリジン誘導体およびその製造法 | |
KR800001591B1 (ko) | 1, 4-디하이드로 피리딘 유도체의 제조방법 | |
JP3897473B2 (ja) | 1,4−ジヒドロピリジン誘導体 | |
JPH0588233B2 (da) | ||
JPS6110576A (ja) | 新規な1,4―ジヒドロピリジン誘導体およびその塩、それらの製造法並びにそれらを含有する循環障害治療剤 | |
FI63022C (fi) | Foerfarande foer framstaellning av vasodilatoriska 1,4-dihydropyridinderivat | |
KR800001611B1 (ko) | 1, 4-디하이드로피리딘 유도체의 제조방법 | |
KR800001593B1 (ko) | 1, 4-디하이드로 피리딘 유도체의 제조방법 | |
JPH06500336A (ja) | ジヒドロピリジン化合物、およびその製造方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAL | Patent in force |
Ref document number: 8503111-0 Format of ref document f/p: F |
|
NUG | Patent has lapsed |
Ref document number: 8503111-0 Format of ref document f/p: F |