SE457000B - Foerfarande foer framstaellning av en carcinostatisk och immunostimulerande tf-2-substans, carcinostatisk tf-2-substans samt carcinostatiskt medel. - Google Patents
Foerfarande foer framstaellning av en carcinostatisk och immunostimulerande tf-2-substans, carcinostatisk tf-2-substans samt carcinostatiskt medel.Info
- Publication number
- SE457000B SE457000B SE8201016A SE8201016A SE457000B SE 457000 B SE457000 B SE 457000B SE 8201016 A SE8201016 A SE 8201016A SE 8201016 A SE8201016 A SE 8201016A SE 457000 B SE457000 B SE 457000B
- Authority
- SE
- Sweden
- Prior art keywords
- precipitate
- water
- substance
- reaction
- sulfuric acid
- Prior art date
Links
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- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 239000003589 local anesthetic agent Substances 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- YKSIHFDRGQQOCJ-LHHMOHDTSA-N mycothione Chemical compound O([C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(=O)[C@@H](NC(C)=O)CSSC[C@H](NC(=O)C)C(=O)N[C@H]1[C@H](O[C@H](CO)[C@@H](O)[C@@H]1O)O[C@@H]1[C@@H]([C@H](O)[C@@H](O)[C@H](O)[C@H]1O)O)[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O YKSIHFDRGQQOCJ-LHHMOHDTSA-N 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229940055729 papain Drugs 0.000 description 1
- 235000019834 papain Nutrition 0.000 description 1
- 210000001539 phagocyte Anatomy 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000009938 salting Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229940001482 sodium sulfite Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 150000003672 ureas Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/05—Immunological preparations stimulating the reticulo-endothelial system, e.g. against cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56022270A JPS57136593A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-210, its preparation, and carcinostatic agent containing the same |
| JP56022274A JPS57136597A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-250, its preparation, and carcinostatic agent containing the same |
| JP56022271A JPS57136594A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-220, its preparation, and carcinostatic agent containing the same |
| JP56022275A JPS57136598A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-300, its preparation, and carcinostatic agent containing the same |
| JP56022272A JPS57136595A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-230, its preparation, and carcinostatic agent containing the same |
| JP56022277A JPS57139089A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-350, its preparation and carcinostatic agent containing the same |
| JP56022276A JPS57139088A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-340, its preparation and carcinostatic agent containing the same |
| JP56022273A JPS57136596A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same |
| JP57011744A JPS58129977A (ja) | 1982-01-29 | 1982-01-29 | 制癌性物質ｔｆ−３００−２及びその製造法並びにこれを含有する制癌剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8201016L SE8201016L (sv) | 1982-08-20 |
| SE457000B true SE457000B (sv) | 1988-11-21 |
Family
ID=27576620
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8201016A SE457000B (sv) | 1981-02-19 | 1982-02-18 | Foerfarande foer framstaellning av en carcinostatisk och immunostimulerande tf-2-substans, carcinostatisk tf-2-substans samt carcinostatiskt medel. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4591558A (fr) |
| AT (1) | AT381722B (fr) |
| BE (1) | BE892204A (fr) |
| CA (1) | CA1184864A (fr) |
| CH (1) | CH651052A5 (fr) |
| DE (1) | DE3205074A1 (fr) |
| DK (1) | DK151640C (fr) |
| FI (1) | FI69096C (fr) |
| FR (1) | FR2499855B1 (fr) |
| GB (1) | GB2093347B (fr) |
| IT (1) | IT1189224B (fr) |
| NL (1) | NL8200640A (fr) |
| NO (1) | NO157426C (fr) |
| NZ (1) | NZ199771A (fr) |
| PT (1) | PT74455B (fr) |
| SE (1) | SE457000B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5931715A (ja) * | 1982-08-17 | 1984-02-20 | Toyama Chem Co Ltd | 制癌性物質ｔｆ−５００の製造法 |
| CN102355838A (zh) * | 2009-02-20 | 2012-02-15 | 弗瑞马斯特公司 | 用于油炸机的托架系统 |
| CN102595987A (zh) | 2009-07-15 | 2012-07-18 | 弗瑞马斯特公司 | 用于深敞口桶式油炸系统的自动化托架/吊篮升降系统 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5461112A (en) * | 1977-10-24 | 1979-05-17 | Ono Pharmaceut Co Ltd | Oncostatic polysaccharide* its preparation* and oncostatic drugs containing it as an effective component |
| JPS5943929B2 (ja) * | 1979-08-13 | 1984-10-25 | サッポロビール株式会社 | 多糖体ｒｂｓ物質，その製法およびそれを有効成分とする抗腫瘍性剤 |
| DE3031152A1 (de) * | 1979-08-24 | 1981-03-19 | Toyama Chemical Co. Ltd., Tokyo | Carcinostatische substanzen, verfahren zur herstellung derselben und mittel mit einem gehalt derselben |
| US4477437A (en) * | 1981-02-19 | 1984-10-16 | Toyama Chemical Co., Ltd. | Substances having carcinostatic and immunostimulating activity |
-
1982
- 1982-02-12 GB GB8204093A patent/GB2093347B/en not_active Expired
- 1982-02-12 DE DE19823205074 patent/DE3205074A1/de active Granted
- 1982-02-17 DK DK069282A patent/DK151640C/da not_active IP Right Cessation
- 1982-02-17 IT IT47817/82A patent/IT1189224B/it active
- 1982-02-17 CH CH979/82A patent/CH651052A5/de not_active IP Right Cessation
- 1982-02-17 CA CA000396425A patent/CA1184864A/fr not_active Expired
- 1982-02-17 FR FR8202601A patent/FR2499855B1/fr not_active Expired
- 1982-02-17 FI FI820527A patent/FI69096C/fi not_active IP Right Cessation
- 1982-02-18 PT PT74455A patent/PT74455B/pt not_active IP Right Cessation
- 1982-02-18 NZ NZ199771A patent/NZ199771A/en unknown
- 1982-02-18 NL NL8200640A patent/NL8200640A/nl not_active Application Discontinuation
- 1982-02-18 SE SE8201016A patent/SE457000B/sv unknown
- 1982-02-18 NO NO820509A patent/NO157426C/no unknown
- 1982-02-19 BE BE0/207355A patent/BE892204A/fr not_active IP Right Cessation
- 1982-02-19 AT AT0064682A patent/AT381722B/de not_active IP Right Cessation
-
1984
- 1984-08-06 US US06/619,895 patent/US4591558A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK69282A (da) | 1982-08-20 |
| AT381722B (de) | 1986-11-25 |
| IT1189224B (it) | 1988-01-28 |
| NO157426B (no) | 1987-12-07 |
| GB2093347B (en) | 1985-03-27 |
| BE892204A (fr) | 1982-08-19 |
| NZ199771A (en) | 1985-09-13 |
| DE3205074A1 (de) | 1982-12-16 |
| NO820509L (no) | 1982-08-20 |
| PT74455A (en) | 1982-03-01 |
| PT74455B (en) | 1984-12-04 |
| CH651052A5 (de) | 1985-08-30 |
| CA1184864A (fr) | 1985-04-02 |
| DK151640C (da) | 1988-06-20 |
| ATA64682A (de) | 1986-04-15 |
| FR2499855A1 (fr) | 1982-08-20 |
| NL8200640A (nl) | 1982-09-16 |
| FI820527L (fi) | 1982-08-20 |
| US4591558A (en) | 1986-05-27 |
| IT8247817A0 (it) | 1982-02-17 |
| DK151640B (da) | 1987-12-21 |
| GB2093347A (en) | 1982-09-02 |
| FR2499855B1 (fr) | 1985-07-12 |
| FI69096B (fi) | 1985-08-30 |
| SE8201016L (sv) | 1982-08-20 |
| NO157426C (no) | 1988-03-16 |
| FI69096C (fi) | 1985-12-10 |
| DE3205074C2 (fr) | 1987-09-24 |
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| NAL | Patent in force |
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