JPS57136596A - Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same - Google Patents
Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the sameInfo
- Publication number
- JPS57136596A JPS57136596A JP56022273A JP2227381A JPS57136596A JP S57136596 A JPS57136596 A JP S57136596A JP 56022273 A JP56022273 A JP 56022273A JP 2227381 A JP2227381 A JP 2227381A JP S57136596 A JPS57136596 A JP S57136596A
- Authority
- JP
- Japan
- Prior art keywords
- carcinostatic
- exhibits
- substance
- carcinoma
- ehrlich
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
NEW MATERIAL:Carcinostatic substance TF-240 or its salt having the following characteristics; light gray to light brown powder; active to inhibit the proliferation of cells of Ehrlich ascites carcinoma of mouse, Ehrlich nodal carcinoma, sarcoma 180 cancer and B-16 melanoma cancer; exhibits immuno-activating activity; insoluble in methanol, acetone, benzene, ethyl acetate, etc.; exhibits no definite melting point and decomposes at 200W215°C; positive to Molish reaction, phenol sulfuric acid reaction, etc.; elemental analysis, C 35W38%, H 4W5%, N 12W14%, etc.
USE: Carcinostatic agent.
PROCESS: Bacerial strain belonging to Fusobacterium genus, e.g. Fusobacterium nucleatum TF-031 (FERM-P No.5077, ATCC-31,647), etc. is cultured under anaerobic conditions, pref. at 7.2W8.2pH and 36W38°C for 1W4 days.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (21)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56022273A JPS57136596A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same |
US06/347,871 US4477437A (en) | 1981-02-19 | 1982-02-11 | Substances having carcinostatic and immunostimulating activity |
GB8204093A GB2093347B (en) | 1981-02-19 | 1982-02-12 | Immunostimulant material tf-2 from fusobacterium sp |
DE19823205074 DE3205074A1 (en) | 1981-02-19 | 1982-02-12 | NEW CARCINOSTATIC AND IMMUNOSTIMULATING SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND CARCINOSTATIC AGENTS WITH A CONTENT THEREOF |
FR8202601A FR2499855B1 (en) | 1981-02-19 | 1982-02-17 | NOVEL CARCINOSTATIC AND IMMUNO-STIMULATING SUBSTANCES, PROCESS FOR PREPARING SAME FROM FUSOBACTERIUM BACTERIA, AND CARCINOSTATIC AGENT CONTAINING SUCH SUBSTANCES |
FI820527A FI69096C (en) | 1981-02-19 | 1982-02-17 | REFRIGERATION FOR CARCINOSTATICS AND IMMUNOSTIMULATION TF-2 SUBSTANCES |
DK069282A DK151640C (en) | 1981-02-19 | 1982-02-17 | PROCEDURE FOR PREPARING RELATIONSHIPS WITH CARCINOSTATIC AND IMMUNOSTIMULATIVE EFFECT |
CA000396425A CA1184864A (en) | 1981-02-19 | 1982-02-17 | Substances having carcinostatic and immunostimulating activity, process for preparing the same and carcinostatic agent containing the same |
DD82237480A DD202891A5 (en) | 1981-02-19 | 1982-02-17 | NEW CARCINOSTATIC AND IMMUNOSTIMULATING SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND CARCINOSTATIC AGENTS WITH A CONTENT OF THE SAME |
IT47817/82A IT1189224B (en) | 1981-02-19 | 1982-02-17 | CARCINOSTATIC AND IMMUNOSTIMULATING SUBSTANCES TF-2, PROCEDURE TO PREPARE THEM AND CARCINOSTATIC AGENT CONTAINING THEM |
CH979/82A CH651052A5 (en) | 1981-02-19 | 1982-02-17 | METHOD FOR PRODUCING A CARCINOSTATIC SUBSTANCE AND CARCINOSTATIC SUBSTANCE. |
NZ199771A NZ199771A (en) | 1981-02-19 | 1982-02-18 | Carcinostatic and immunostimulating substances produced by fusobacterium nucleatum |
NO820509A NO157426C (en) | 1981-02-19 | 1982-02-18 | PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE COMPOUNDS FOR THE CULTIVATION OF MICRO-ORGANISMS. |
NL8200640A NL8200640A (en) | 1981-02-19 | 1982-02-18 | NEW CARCINOSTATIC SUBSTANCES, PREPARATIONS CONTAINING THEM AND METHOD FOR THE PREPARATION THEREOF. |
SE8201016A SE457000B (en) | 1981-02-19 | 1982-02-18 | PROCEDURE FOR PREPARING A CARCINOSTATIC AND IMMUNOSTIMULATING TF-2 SUBSTANCE, CARCINOSTATIC TF-2 SUBSTANCE AND CARCINOSTATIC AGENT. |
KR8200714A KR890002256B1 (en) | 1981-02-19 | 1982-02-18 | Process for preparing anticanser tf-2 |
PT74455A PT74455B (en) | 1981-02-19 | 1982-02-18 | Process for preparing novel substances having carcinostatic and immunostimulating activity and of a carcinostatic agent containing same |
BE0/207355A BE892204A (en) | 1981-02-19 | 1982-02-19 | NOVEL CARCINOSTATIC AND IMMUNQ-STIMULATING SUBSTANCES, PROCESS FOR PREPARING THEM FROM FUSOBACTERIUM BACTERIA, AND CARCINOSTATIC AGENT CONTAINING SUCH SUBSTANCES |
AT0064682A AT381722B (en) | 1981-02-19 | 1982-02-19 | METHOD FOR PRODUCING A NEW CARCINOSTATIC SUBSTANCE |
US06/619,895 US4591558A (en) | 1981-02-19 | 1984-08-06 | Novel substances having antitumor and immunostimulating activity, process for preparing the same and antitumor agent containing the same |
DK251186A DK165641C (en) | 1981-02-19 | 1986-05-29 | PROCEDURE FOR PREPARING TF-220, TF-230 AND TF-240 COMPOUNDS AND THE SIMILAR PROTEIN-FREE COMPOUNDS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56022273A JPS57136596A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57136596A true JPS57136596A (en) | 1982-08-23 |
JPH021154B2 JPH021154B2 (en) | 1990-01-10 |
Family
ID=12078149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56022273A Granted JPS57136596A (en) | 1981-02-19 | 1981-02-19 | Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57136596A (en) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1625944A1 (en) | 2004-08-13 | 2006-02-15 | Fuji Photo Film Co., Ltd. | Method of manufacturing lithographic printing plate support |
EP1712368A1 (en) | 2005-04-13 | 2006-10-18 | Fuji Photo Film Co., Ltd. | Method of manufacturing a support for a lithographic printing plate |
EP2017070A2 (en) | 2007-07-16 | 2009-01-21 | Lafabrica S.R.L. | Machine for compacting collapsable containers, particulary bottles made of plastic material and the like |
EP2100677A1 (en) | 2008-03-06 | 2009-09-16 | Fujifilm Corporation | Method of manufacturing aluminum alloy plate for lithographic printing plate, aluminum alloy plate for lithographic printing plate obtained thereby and lithographic printing plate support |
WO2010150810A1 (en) | 2009-06-26 | 2010-12-29 | 富士フイルム株式会社 | Light reflecting substrate and process for manufacture thereof |
WO2011037005A1 (en) | 2009-09-24 | 2011-03-31 | 富士フイルム株式会社 | Lithographic printing original plate |
WO2011078010A1 (en) | 2009-12-25 | 2011-06-30 | 富士フイルム株式会社 | Insulated substrate, process for production of insulated substrate, process for formation of wiring line, wiring substrate, and light-emitting element |
EP2384100A2 (en) | 2010-04-28 | 2011-11-02 | Fujifilm Corporation | Insulated light-reflective substrate |
EP2420869A2 (en) | 2010-08-16 | 2012-02-22 | Fujifilm Corporation | Radiation reflection plate for LED |
WO2013005717A1 (en) | 2011-07-04 | 2013-01-10 | 富士フイルム株式会社 | Insulating reflective substrate and method for producing same |
EP2586621A1 (en) | 2011-10-28 | 2013-05-01 | Fujifilm Corporation | Manufacturing method and manufacturing apparatus of support for planographic printing plate |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0578238U (en) * | 1992-04-01 | 1993-10-26 | 嵜山 政雄 | Baby bottle with forward and reverse scale |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5499918A (en) * | 1978-01-25 | 1979-08-07 | Sony Corp | Controlling of motor speed |
-
1981
- 1981-02-19 JP JP56022273A patent/JPS57136596A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5499918A (en) * | 1978-01-25 | 1979-08-07 | Sony Corp | Controlling of motor speed |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1625944A1 (en) | 2004-08-13 | 2006-02-15 | Fuji Photo Film Co., Ltd. | Method of manufacturing lithographic printing plate support |
EP1712368A1 (en) | 2005-04-13 | 2006-10-18 | Fuji Photo Film Co., Ltd. | Method of manufacturing a support for a lithographic printing plate |
EP2017070A2 (en) | 2007-07-16 | 2009-01-21 | Lafabrica S.R.L. | Machine for compacting collapsable containers, particulary bottles made of plastic material and the like |
EP2100677A1 (en) | 2008-03-06 | 2009-09-16 | Fujifilm Corporation | Method of manufacturing aluminum alloy plate for lithographic printing plate, aluminum alloy plate for lithographic printing plate obtained thereby and lithographic printing plate support |
WO2010150810A1 (en) | 2009-06-26 | 2010-12-29 | 富士フイルム株式会社 | Light reflecting substrate and process for manufacture thereof |
WO2011037005A1 (en) | 2009-09-24 | 2011-03-31 | 富士フイルム株式会社 | Lithographic printing original plate |
WO2011078010A1 (en) | 2009-12-25 | 2011-06-30 | 富士フイルム株式会社 | Insulated substrate, process for production of insulated substrate, process for formation of wiring line, wiring substrate, and light-emitting element |
EP2384100A2 (en) | 2010-04-28 | 2011-11-02 | Fujifilm Corporation | Insulated light-reflective substrate |
EP2420869A2 (en) | 2010-08-16 | 2012-02-22 | Fujifilm Corporation | Radiation reflection plate for LED |
WO2013005717A1 (en) | 2011-07-04 | 2013-01-10 | 富士フイルム株式会社 | Insulating reflective substrate and method for producing same |
EP2586621A1 (en) | 2011-10-28 | 2013-05-01 | Fujifilm Corporation | Manufacturing method and manufacturing apparatus of support for planographic printing plate |
Also Published As
Publication number | Publication date |
---|---|
JPH021154B2 (en) | 1990-01-10 |
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