JPS57136596A - Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same - Google Patents

Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same

Info

Publication number
JPS57136596A
JPS57136596A JP56022273A JP2227381A JPS57136596A JP S57136596 A JPS57136596 A JP S57136596A JP 56022273 A JP56022273 A JP 56022273A JP 2227381 A JP2227381 A JP 2227381A JP S57136596 A JPS57136596 A JP S57136596A
Authority
JP
Japan
Prior art keywords
carcinostatic
exhibits
substance
carcinoma
ehrlich
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56022273A
Other languages
Japanese (ja)
Other versions
JPH021154B2 (en
Inventor
Kenzo Tamai
Isamu Saikawa
Takashi Yasuda
Shohachi Murakami
Toyoo Maeda
Hisatsugu Tsuda
Hiroshi Sakai
Masatoshi Sugita
Yoshiko Yamamoto
Takashi Minami
Takako Hori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP56022273A priority Critical patent/JPS57136596A/en
Priority to US06/347,871 priority patent/US4477437A/en
Priority to DE19823205074 priority patent/DE3205074A1/en
Priority to GB8204093A priority patent/GB2093347B/en
Priority to CA000396425A priority patent/CA1184864A/en
Priority to DK069282A priority patent/DK151640C/en
Priority to DD82237480A priority patent/DD202891A5/en
Priority to FR8202601A priority patent/FR2499855B1/en
Priority to FI820527A priority patent/FI69096C/en
Priority to CH979/82A priority patent/CH651052A5/en
Priority to IT47817/82A priority patent/IT1189224B/en
Priority to PT74455A priority patent/PT74455B/en
Priority to SE8201016A priority patent/SE457000B/en
Priority to NZ199771A priority patent/NZ199771A/en
Priority to KR8200714A priority patent/KR890002256B1/en
Priority to NO820509A priority patent/NO157426C/en
Priority to NL8200640A priority patent/NL8200640A/en
Priority to BE0/207355A priority patent/BE892204A/en
Priority to AT0064682A priority patent/AT381722B/en
Publication of JPS57136596A publication Critical patent/JPS57136596A/en
Priority to US06/619,895 priority patent/US4591558A/en
Priority to DK251186A priority patent/DK165641C/en
Publication of JPH021154B2 publication Critical patent/JPH021154B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:Carcinostatic substance TF-240 or its salt having the following characteristics; light gray to light brown powder; active to inhibit the proliferation of cells of Ehrlich ascites carcinoma of mouse, Ehrlich nodal carcinoma, sarcoma 180 cancer and B-16 melanoma cancer; exhibits immuno-activating activity; insoluble in methanol, acetone, benzene, ethyl acetate, etc.; exhibits no definite melting point and decomposes at 200W215°C; positive to Molish reaction, phenol sulfuric acid reaction, etc.; elemental analysis, C 35W38%, H 4W5%, N 12W14%, etc.
USE: Carcinostatic agent.
PROCESS: Bacerial strain belonging to Fusobacterium genus, e.g. Fusobacterium nucleatum TF-031 (FERM-P No.5077, ATCC-31,647), etc. is cultured under anaerobic conditions, pref. at 7.2W8.2pH and 36W38°C for 1W4 days.
COPYRIGHT: (C)1982,JPO&Japio
JP56022273A 1981-02-19 1981-02-19 Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same Granted JPS57136596A (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
JP56022273A JPS57136596A (en) 1981-02-19 1981-02-19 Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same
US06/347,871 US4477437A (en) 1981-02-19 1982-02-11 Substances having carcinostatic and immunostimulating activity
DE19823205074 DE3205074A1 (en) 1981-02-19 1982-02-12 NEW CARCINOSTATIC AND IMMUNOSTIMULATING SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND CARCINOSTATIC AGENTS WITH A CONTENT THEREOF
GB8204093A GB2093347B (en) 1981-02-19 1982-02-12 Immunostimulant material tf-2 from fusobacterium sp
CA000396425A CA1184864A (en) 1981-02-19 1982-02-17 Substances having carcinostatic and immunostimulating activity, process for preparing the same and carcinostatic agent containing the same
DK069282A DK151640C (en) 1981-02-19 1982-02-17 PROCEDURE FOR PREPARING RELATIONSHIPS WITH CARCINOSTATIC AND IMMUNOSTIMULATIVE EFFECT
DD82237480A DD202891A5 (en) 1981-02-19 1982-02-17 NEW CARCINOSTATIC AND IMMUNOSTIMULATING SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND CARCINOSTATIC AGENTS WITH A CONTENT OF THE SAME
FR8202601A FR2499855B1 (en) 1981-02-19 1982-02-17 NOVEL CARCINOSTATIC AND IMMUNO-STIMULATING SUBSTANCES, PROCESS FOR PREPARING SAME FROM FUSOBACTERIUM BACTERIA, AND CARCINOSTATIC AGENT CONTAINING SUCH SUBSTANCES
FI820527A FI69096C (en) 1981-02-19 1982-02-17 REFRIGERATION FOR CARCINOSTATICS AND IMMUNOSTIMULATION TF-2 SUBSTANCES
CH979/82A CH651052A5 (en) 1981-02-19 1982-02-17 METHOD FOR PRODUCING A CARCINOSTATIC SUBSTANCE AND CARCINOSTATIC SUBSTANCE.
IT47817/82A IT1189224B (en) 1981-02-19 1982-02-17 CARCINOSTATIC AND IMMUNOSTIMULATING SUBSTANCES TF-2, PROCEDURE TO PREPARE THEM AND CARCINOSTATIC AGENT CONTAINING THEM
PT74455A PT74455B (en) 1981-02-19 1982-02-18 Process for preparing novel substances having carcinostatic and immunostimulating activity and of a carcinostatic agent containing same
SE8201016A SE457000B (en) 1981-02-19 1982-02-18 PROCEDURE FOR PREPARING A CARCINOSTATIC AND IMMUNOSTIMULATING TF-2 SUBSTANCE, CARCINOSTATIC TF-2 SUBSTANCE AND CARCINOSTATIC AGENT.
NZ199771A NZ199771A (en) 1981-02-19 1982-02-18 Carcinostatic and immunostimulating substances produced by fusobacterium nucleatum
KR8200714A KR890002256B1 (en) 1981-02-19 1982-02-18 Process for preparing anticanser tf-2
NO820509A NO157426C (en) 1981-02-19 1982-02-18 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE COMPOUNDS FOR THE CULTIVATION OF MICRO-ORGANISMS.
NL8200640A NL8200640A (en) 1981-02-19 1982-02-18 NEW CARCINOSTATIC SUBSTANCES, PREPARATIONS CONTAINING THEM AND METHOD FOR THE PREPARATION THEREOF.
BE0/207355A BE892204A (en) 1981-02-19 1982-02-19 NOVEL CARCINOSTATIC AND IMMUNQ-STIMULATING SUBSTANCES, PROCESS FOR PREPARING THEM FROM FUSOBACTERIUM BACTERIA, AND CARCINOSTATIC AGENT CONTAINING SUCH SUBSTANCES
AT0064682A AT381722B (en) 1981-02-19 1982-02-19 METHOD FOR PRODUCING A NEW CARCINOSTATIC SUBSTANCE
US06/619,895 US4591558A (en) 1981-02-19 1984-08-06 Novel substances having antitumor and immunostimulating activity, process for preparing the same and antitumor agent containing the same
DK251186A DK165641C (en) 1981-02-19 1986-05-29 PROCEDURE FOR PREPARING TF-220, TF-230 AND TF-240 COMPOUNDS AND THE SIMILAR PROTEIN-FREE COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56022273A JPS57136596A (en) 1981-02-19 1981-02-19 Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same

Publications (2)

Publication Number Publication Date
JPS57136596A true JPS57136596A (en) 1982-08-23
JPH021154B2 JPH021154B2 (en) 1990-01-10

Family

ID=12078149

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56022273A Granted JPS57136596A (en) 1981-02-19 1981-02-19 Carcinostatic substance tf-240, its preparation, and carcinostatic agent containing the same

Country Status (1)

Country Link
JP (1) JPS57136596A (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1625944A1 (en) 2004-08-13 2006-02-15 Fuji Photo Film Co., Ltd. Method of manufacturing lithographic printing plate support
EP1712368A1 (en) 2005-04-13 2006-10-18 Fuji Photo Film Co., Ltd. Method of manufacturing a support for a lithographic printing plate
EP2017070A2 (en) 2007-07-16 2009-01-21 Lafabrica S.R.L. Machine for compacting collapsable containers, particulary bottles made of plastic material and the like
EP2100677A1 (en) 2008-03-06 2009-09-16 Fujifilm Corporation Method of manufacturing aluminum alloy plate for lithographic printing plate, aluminum alloy plate for lithographic printing plate obtained thereby and lithographic printing plate support
WO2010150810A1 (en) 2009-06-26 2010-12-29 富士フイルム株式会社 Light reflecting substrate and process for manufacture thereof
WO2011037005A1 (en) 2009-09-24 2011-03-31 富士フイルム株式会社 Lithographic printing original plate
WO2011078010A1 (en) 2009-12-25 2011-06-30 富士フイルム株式会社 Insulated substrate, process for production of insulated substrate, process for formation of wiring line, wiring substrate, and light-emitting element
EP2384100A2 (en) 2010-04-28 2011-11-02 Fujifilm Corporation Insulated light-reflective substrate
EP2420869A2 (en) 2010-08-16 2012-02-22 Fujifilm Corporation Radiation reflection plate for LED
WO2013005717A1 (en) 2011-07-04 2013-01-10 富士フイルム株式会社 Insulating reflective substrate and method for producing same
EP2586621A1 (en) 2011-10-28 2013-05-01 Fujifilm Corporation Manufacturing method and manufacturing apparatus of support for planographic printing plate

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0578238U (en) * 1992-04-01 1993-10-26 嵜山 政雄 Baby bottle with forward and reverse scale

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5499918A (en) * 1978-01-25 1979-08-07 Sony Corp Controlling of motor speed

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5499918A (en) * 1978-01-25 1979-08-07 Sony Corp Controlling of motor speed

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1625944A1 (en) 2004-08-13 2006-02-15 Fuji Photo Film Co., Ltd. Method of manufacturing lithographic printing plate support
EP1712368A1 (en) 2005-04-13 2006-10-18 Fuji Photo Film Co., Ltd. Method of manufacturing a support for a lithographic printing plate
EP2017070A2 (en) 2007-07-16 2009-01-21 Lafabrica S.R.L. Machine for compacting collapsable containers, particulary bottles made of plastic material and the like
EP2100677A1 (en) 2008-03-06 2009-09-16 Fujifilm Corporation Method of manufacturing aluminum alloy plate for lithographic printing plate, aluminum alloy plate for lithographic printing plate obtained thereby and lithographic printing plate support
WO2010150810A1 (en) 2009-06-26 2010-12-29 富士フイルム株式会社 Light reflecting substrate and process for manufacture thereof
WO2011037005A1 (en) 2009-09-24 2011-03-31 富士フイルム株式会社 Lithographic printing original plate
WO2011078010A1 (en) 2009-12-25 2011-06-30 富士フイルム株式会社 Insulated substrate, process for production of insulated substrate, process for formation of wiring line, wiring substrate, and light-emitting element
EP2384100A2 (en) 2010-04-28 2011-11-02 Fujifilm Corporation Insulated light-reflective substrate
EP2420869A2 (en) 2010-08-16 2012-02-22 Fujifilm Corporation Radiation reflection plate for LED
WO2013005717A1 (en) 2011-07-04 2013-01-10 富士フイルム株式会社 Insulating reflective substrate and method for producing same
EP2586621A1 (en) 2011-10-28 2013-05-01 Fujifilm Corporation Manufacturing method and manufacturing apparatus of support for planographic printing plate

Also Published As

Publication number Publication date
JPH021154B2 (en) 1990-01-10

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