JPS5732297A - Carcinostatic substance tf-150, its preparation, and carcinostatic agent containing the same - Google Patents
Carcinostatic substance tf-150, its preparation, and carcinostatic agent containing the sameInfo
- Publication number
- JPS5732297A JPS5732297A JP10812480A JP10812480A JPS5732297A JP S5732297 A JPS5732297 A JP S5732297A JP 10812480 A JP10812480 A JP 10812480A JP 10812480 A JP10812480 A JP 10812480A JP S5732297 A JPS5732297 A JP S5732297A
- Authority
- JP
- Japan
- Prior art keywords
- carcinostatic
- reaction
- substance
- melting point
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:Carcinostatic substance TF-150. It has the following characteristics: appearance, light grey to pale brown powder; melting point, no definite melting point, starts to decompose at 110°C, and vigorously decomposes at ≥200°C; elemental analysis, C 31.0W34.0%, H 4.0W4.4%, N 2.8W3.2% solubility, soluble in water, insoluble in methanol, acetone, chloroform, diethyl ether, etc.; color reaction, positive to Molish reaction, phenol-sulfuric acid reaction, etc., negative to ninhydrin reaction.
USE: Carcinostatic agent. The substance inhibits the growth of Ehrlich ascites carcinoma of mouse, and has immuno-activating activity.
PROCESS: TF-150-producing bacteria belonging to Fusobacterium genus, e.g. Fusobacterium nucleatum TF-031 (FERM-P No.5077), is cultured, and the cultured liquid mixed with a hydrophilic organic solvent to obtain precipitate. The objective TF-150 is separated from the water-soluble component of the precipitate.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10812480A JPS5732297A (en) | 1980-08-06 | 1980-08-06 | Carcinostatic substance tf-150, its preparation, and carcinostatic agent containing the same |
DE19803031152 DE3031152A1 (en) | 1979-08-24 | 1980-08-18 | CARCINOSTATIC SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND MEDIUM WITH A CONTENT THEREOF |
GB8027026A GB2059969B (en) | 1979-08-24 | 1980-08-19 | Fusobacterium culture extracts |
CA000358667A CA1174618A (en) | 1979-08-24 | 1980-08-20 | Substances having carcinostatic and immunostimulating activity, process for preparing the same and carcinostatic agent containing the same |
AU61646/80A AU529076B2 (en) | 1979-08-24 | 1980-08-21 | Carcinostatic agents |
AT0426480A AT375674B (en) | 1979-08-24 | 1980-08-21 | METHOD FOR PRODUCING NEW CARCINOSTATIC SUBSTANCES |
FI802641A FI68080C (en) | 1979-08-24 | 1980-08-21 | FOER FARING FOR CARCINOSTATICS AND IMMUNOSISCULATION OF SUBSTANCES |
BE0/201815A BE884864A (en) | 1979-08-24 | 1980-08-21 | NOVEL SUBSTANCES PRODUCED BY FUSOBACTERIUM BACTERIA, PREPARATION METHOD THEREOF AND THERAPEUTIC APPLICATION THEREOF |
CH6297/80A CH648042A5 (en) | 1979-08-24 | 1980-08-21 | CARCINOSTATIC SUBSTANCES, METHOD FOR THE PRODUCTION THEREOF AND MEDIUM WITH A CONTENT THEREOF. |
NL8004759A NL8004759A (en) | 1979-08-24 | 1980-08-22 | NEW SUBSTANCES WITH CARCINOSTATIC AND IMMUNO-STIMULATING EFFECTS, METHOD FOR THE PREPARATION THEREOF AND CARCINOSTATIC PREPARATIONS CONTAINING THESE SUBSTANCES. |
NZ194744A NZ194744A (en) | 1979-08-24 | 1980-08-22 | Preparation of carcinostatic and immunostimulating tf-substances from fusobacterium |
FR8018396A FR2463619A1 (en) | 1979-08-24 | 1980-08-22 | NEW SUBSTANCES PRODUCED BY BACTERIA OF THE GENUS FUSOBACTERIUM, PROCESS FOR PREPARING THEM AND THEIR USE IN THERAPEUTICS |
IT49541/80A IT1181595B (en) | 1979-08-24 | 1980-08-22 | CARCINOSTATIC SUBSTANCES AND IMMUNE STIMULANTS PROCEDURE TO PREPARE THEM AND CARCINOSTATIC AGENT CONTAINING THEM |
DK361680A DK151639C (en) | 1979-08-24 | 1980-08-22 | PROCEDURE FOR PREPARING TF-100 OR FRACTIONS WITH CARCINOSTATIC AND IMMUNOSTIMULATING ACTIVITY |
SE8005921A SE446406B (en) | 1979-08-24 | 1980-08-22 | NEW COMPOUNDS WITH CARCINOSTATIC AND IMMUNOSTIMULATING EFFECTS PRODUCED BY CULTIVATION OF FUSOBACTERIUM NUCLEATUM TF-031 (FERM 5077, ATCC 31647), PROCEDURE FOR THE PRODUCTION OF SAME AND CARCINOSTATIC |
NO802499A NO155697C (en) | 1979-08-24 | 1980-08-22 | PROCEDURE FOR THE PREPARATION OF PHYSIOLOGICALLY ACTIVE COMPOUNDS. |
PT71730A PT71730A (en) | 1979-08-24 | 1980-08-22 | Process for preparing novel substances having carcinostatic immunostimulating activity and a carcinostatic agent containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10812480A JPS5732297A (en) | 1980-08-06 | 1980-08-06 | Carcinostatic substance tf-150, its preparation, and carcinostatic agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5732297A true JPS5732297A (en) | 1982-02-20 |
JPS6353200B2 JPS6353200B2 (en) | 1988-10-21 |
Family
ID=14476532
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10812480A Granted JPS5732297A (en) | 1979-08-24 | 1980-08-06 | Carcinostatic substance tf-150, its preparation, and carcinostatic agent containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5732297A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6255362U (en) * | 1985-09-25 | 1987-04-06 |
-
1980
- 1980-08-06 JP JP10812480A patent/JPS5732297A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6255362U (en) * | 1985-09-25 | 1987-04-06 |
Also Published As
Publication number | Publication date |
---|---|
JPS6353200B2 (en) | 1988-10-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES477060A1 (en) | Interferon and preparations containing interferon | |
ES478967A1 (en) | 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds | |
JPS5743696A (en) | Preparation of human luteinizing hormone | |
JPS5732297A (en) | Carcinostatic substance tf-150, its preparation, and carcinostatic agent containing the same | |
JPS5732293A (en) | Carcinostatic substance tf-132b, its preparation, and carcinostatic agent containing the same | |
JPS5732296A (en) | Carcinostatic substance tf-140, its preparation, and carcinostatic agent containing the same | |
JPS5732294A (en) | Carcinostatic substance tf-133b, its preparation, and carcinostatic agent containing the same | |
JPS5732295A (en) | Carcinostatic substance tf-1323, its preparation, and carcinostatic agent containing the same | |
JPS57150350A (en) | Formula feed for lugworm | |
JPS5630995A (en) | Carcinostatic substance tf-100, its preparation, and carcinostatic comprizing it | |
JPS5630997A (en) | Carcinostatic substance tf-120, its preparation, and carcinostatic comprizing it | |
JPS5574797A (en) | Preparation of protein polysaccharide having anti-tumor activity | |
JPS57139091A (en) | Carcinostatic substance tv-130, its preparation and carcinostatic agent containing the same | |
JPS5630996A (en) | Carcinostatic substance tf-110, its preparation, and carcinostatic comprizing it | |
JPS57136597A (en) | Carcinostatic substance tf-250, its preparation, and carcinostatic agent containing the same | |
JPS57139088A (en) | Carcinostatic substance tf-340, its preparation and carcinostatic agent containing the same | |
JPS57139089A (en) | Carcinostatic substance tf-350, its preparation and carcinostatic agent containing the same | |
JPS56154479A (en) | Clathrate composition consisting of vitamin e and cyclodextrin and its preparation | |
JPS5653101A (en) | Polysaccharide ks-2-d and its preparation | |
JPS57136594A (en) | Carcinostatic substance tf-220, its preparation, and carcinostatic agent containing the same | |
JPS57136593A (en) | Carcinostatic substance tf-210, its preparation, and carcinostatic agent containing the same | |
JPS5645496A (en) | Carcinostatic substance, tf-130, its preparation and carcinostatic preparation containing the same | |
JPS5270084A (en) | Polysaccharide ax | |
Razumov et al. | The rooster posterior hypophysis under conditions of longterm training for emotional stress. | |
JPS5581896A (en) | Biologically active substance from beefsteak plants of family labiatae and its preparation |