JPS54107511A - Preparation of bio-active substance - Google Patents

Preparation of bio-active substance

Info

Publication number
JPS54107511A
JPS54107511A JP1360478A JP1360478A JPS54107511A JP S54107511 A JPS54107511 A JP S54107511A JP 1360478 A JP1360478 A JP 1360478A JP 1360478 A JP1360478 A JP 1360478A JP S54107511 A JPS54107511 A JP S54107511A
Authority
JP
Japan
Prior art keywords
plasminogen
cells
activating factor
bio
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1360478A
Other languages
Japanese (ja)
Other versions
JPS6210208B2 (en
Inventor
Sadayoshi Horiguchi
Akio Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP1360478A priority Critical patent/JPS54107511A/en
Publication of JPS54107511A publication Critical patent/JPS54107511A/en
Publication of JPS6210208B2 publication Critical patent/JPS6210208B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To prepare a plasminogen-activating factor, industrially in high yield, by contacting animal-originated cells available in large quantities as concentrated dispersion, with a threonine-containing solution.
CONSTITUTION: Animal-originated cells capable of producing plasminogen-activating factor, e.g. long cells of mouse fetus, kidney cells of African green guenon, factor, etc. are cultured in a medium containing 0.1W0.4 W/V % of threonine at 15W40°C (pref. 25W40°C) and pH5W9 (pref. 6W8), for usually 4W30 days, and the objective plasminogen-activating factor is separated from the medium.
COPYRIGHT: (C)1979,JPO&Japio
JP1360478A 1978-02-10 1978-02-10 Preparation of bio-active substance Granted JPS54107511A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1360478A JPS54107511A (en) 1978-02-10 1978-02-10 Preparation of bio-active substance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1360478A JPS54107511A (en) 1978-02-10 1978-02-10 Preparation of bio-active substance

Publications (2)

Publication Number Publication Date
JPS54107511A true JPS54107511A (en) 1979-08-23
JPS6210208B2 JPS6210208B2 (en) 1987-03-05

Family

ID=11837822

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1360478A Granted JPS54107511A (en) 1978-02-10 1978-02-10 Preparation of bio-active substance

Country Status (1)

Country Link
JP (1) JPS54107511A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0276823A (en) * 1980-04-03 1990-03-16 Abbott Lab Thrombus dissolving agent

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04128976U (en) * 1991-05-16 1992-11-25 日本精工株式会社 telescoping steering column

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0276823A (en) * 1980-04-03 1990-03-16 Abbott Lab Thrombus dissolving agent

Also Published As

Publication number Publication date
JPS6210208B2 (en) 1987-03-05

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