SE453292B - Nya 2-(hydroxifenyl)-indoler och 2-(alkanoyloxifenyl)-indoler, forfarande for deras framstellning och lekemedel till anvendning som antitumormedel - Google Patents

Nya 2-(hydroxifenyl)-indoler och 2-(alkanoyloxifenyl)-indoler, forfarande for deras framstellning och lekemedel till anvendning som antitumormedel

Info

Publication number
SE453292B
SE453292B SE8205105A SE8205105A SE453292B SE 453292 B SE453292 B SE 453292B SE 8205105 A SE8205105 A SE 8205105A SE 8205105 A SE8205105 A SE 8205105A SE 453292 B SE453292 B SE 453292B
Authority
SE
Sweden
Prior art keywords
group
hydrogen
groups
hydroxy
alkyl group
Prior art date
Application number
SE8205105A
Other languages
English (en)
Swedish (sv)
Other versions
SE8205105D0 (sv
SE8205105L (sv
Inventor
Angerer E Von
H Schonenberger
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of SE8205105D0 publication Critical patent/SE8205105D0/xx
Publication of SE8205105L publication Critical patent/SE8205105L/xx
Publication of SE453292B publication Critical patent/SE453292B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8205105A 1981-09-10 1982-09-08 Nya 2-(hydroxifenyl)-indoler och 2-(alkanoyloxifenyl)-indoler, forfarande for deras framstellning och lekemedel till anvendning som antitumormedel SE453292B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3135841 1981-09-10

Publications (3)

Publication Number Publication Date
SE8205105D0 SE8205105D0 (sv) 1982-09-08
SE8205105L SE8205105L (sv) 1983-03-11
SE453292B true SE453292B (sv) 1988-01-25

Family

ID=6141292

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8205105A SE453292B (sv) 1981-09-10 1982-09-08 Nya 2-(hydroxifenyl)-indoler och 2-(alkanoyloxifenyl)-indoler, forfarande for deras framstellning och lekemedel till anvendning som antitumormedel

Country Status (20)

Country Link
US (2) US4543360A (fr)
JP (3) JPS5857361A (fr)
AT (1) AT379149B (fr)
BE (1) BE894332A (fr)
CA (1) CA1185609A (fr)
CH (1) CH657123A5 (fr)
DD (1) DD211339A5 (fr)
DK (1) DK157849C (fr)
EG (1) EG15840A (fr)
ES (2) ES515590A0 (fr)
FI (1) FI76071C (fr)
FR (1) FR2512446B1 (fr)
GB (1) GB2111478B (fr)
IT (1) IT1198440B (fr)
NL (1) NL8203512A (fr)
NO (1) NO157173C (fr)
PT (1) PT75526B (fr)
SE (1) SE453292B (fr)
YU (2) YU202382A (fr)
ZA (1) ZA826637B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5962566A (ja) * 1982-10-01 1984-04-10 Tanabe Seiyaku Co Ltd ヒドロキシインド−ルの製法
US4847283A (en) * 1983-01-10 1989-07-11 Harendza Harinxma Alfred J Ointment and method for treating skin lesions due to herpes virus
US4668755A (en) * 1984-08-10 1987-05-26 General Electric Company High molecular weight siloxane polyimides, intermediates therefor, and methods for their preparation and use
JPS6160648A (ja) * 1984-08-31 1986-03-28 Teikoku Hormone Mfg Co Ltd ２−（３，５−ジアルキル−４−ヒドロキシフエニル）インド−ル誘導体
ES2016313B3 (es) * 1986-10-03 1990-11-01 Asta Pharma Ag Compuestos de complejos diamina-platino (ii) con un anillo fenil-indol hidroxilado.
DE3821148A1 (de) * 1988-06-23 1989-12-28 Erwin Von Dr Angerer Aminoalkylindole, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US5061700A (en) * 1989-11-16 1991-10-29 Gordon Jay Dow Glyceryl acetate ointment vehicles
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
EP0639567A1 (fr) * 1992-05-08 1995-02-22 Otsuka Pharmaceutical Factory, Inc. Derive d'indole
FR2779723B1 (fr) * 1998-06-12 2000-07-13 Cird Galderma Composes biaryles heterocycliques aromatiques, compositions pharmaceutiques et cosmetiques les contenant et utilisations
US6117904A (en) * 1999-09-03 2000-09-12 Murphy; Donald M. Treatment of pruritus
US6541517B1 (en) 1999-09-03 2003-04-01 Donald M. Murphy Treatment of skin disorders
GB201217285D0 (en) * 2012-09-27 2012-11-14 Univ Central Lancashire Indole derivatives

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2825734A (en) * 1955-04-11 1958-03-04 Upjohn Co Reduction of carbonylic radicals in indolyl-3 compounds
US3159646A (en) * 1960-01-13 1964-12-01 American Cyanamid Co Alkenoylamido and oxy phenylbenzotriazoles
US3023321A (en) * 1960-02-15 1962-02-27 Zenith Radio Corp Transistor switching apparatus with leakage resistance stabilizing means
US3214436A (en) * 1960-12-19 1965-10-26 American Cyanamid Co Benzotriazole compounds
GB1007583A (en) * 1961-08-04 1965-10-13 Upjohn Co Improvements in or relating to benz[e,d]indole derivatives and the manufacture thereof
FR3460M (fr) * 1964-06-10 1965-07-26 Robert Jean Médicament présentant notamment des propriétés bradycardisantes a base de o-diéthylamino-éthoxy-2-phényl-2-indole.
US3352856A (en) * 1965-12-20 1967-11-14 Upjohn Co 2-(p-alkoxyphenyl)-3-substituted indoles
NL6913261A (fr) * 1968-09-09 1970-03-11
US3870519A (en) * 1971-06-23 1975-03-11 Ciba Geigy Ag S-triazine derivatives as ultraviolet protecting agents
US3799943A (en) * 1971-06-23 1974-03-26 Sterling Drug Inc 1,2-diphenylindoles
JPS5020808A (fr) * 1973-06-26 1975-03-05
US3978074A (en) * 1973-11-21 1976-08-31 Uniroyal Inc. Method of making hydroxyarylbenzotriazoles and their N-oxides
FR2273841A1 (fr) * 1974-06-05 1976-01-02 Labaz Nouveaux stabilisants des polymeres et copolymeres du chlorure de vinyle
AT352111B (de) * 1974-06-05 1979-09-10 Labaz Verfahren zur herstellung von neuen indolderivaten
FR2275461A1 (fr) * 1974-06-18 1976-01-16 Labaz Nouveaux stabilisants des polymeres et copolymeres du chlorure de vinyle
AT352113B (de) * 1974-06-18 1979-09-10 Labaz Verfahren zur herstellung neuer 2- phenyl-indolderivate
US4017508A (en) * 1974-07-01 1977-04-12 Eastman Kodak Company Benzoxazole ultraviolet stabilizers and their use in organic compositions
FR2304606A1 (fr) * 1975-03-21 1976-10-15 Labaz Nouveaux stabilisants des polymeres et copolymeres du chlorure de vinyle
FR2321875A1 (fr) * 1975-08-29 1977-03-25 Oreal Compositions anti-solaires contenant des derives du phenyl-2 indole
JPS52133977A (en) * 1976-04-30 1977-11-09 Labaz 22*3**methoxyy4**hydoxyyphenyl**indole
FR2358395A2 (fr) * 1976-07-15 1978-02-10 Labaz Nouveaux derives du phenyl-2 indole utiles comme stabilisants des polymeres et copolymeres du chlorure de vinyle
FR2358396A1 (fr) * 1976-07-15 1978-02-10 Labaz Nouveau procede de preparation de derives du phenyl-2 indole
DE2909779A1 (de) * 1979-03-13 1980-09-18 Thomae Gmbh Dr K Neue indolderivate, deren herstellung und deren verwendung als arzneimittel

Also Published As

Publication number Publication date
US4661511A (en) 1987-04-28
CH657123A5 (de) 1986-08-15
PT75526B (de) 1986-03-20
GB2111478B (en) 1986-01-02
IT1198440B (it) 1988-12-21
JPH0317833B2 (fr) 1991-03-11
ES515589A0 (es) 1983-06-01
DK404282A (da) 1983-03-11
FI823125L (fi) 1983-03-11
FR2512446B1 (fr) 1985-07-12
ES8307747A1 (es) 1983-07-01
PT75526A (de) 1982-10-01
AT379149B (de) 1985-11-25
FI76071C (fi) 1988-09-09
JPS62252765A (ja) 1987-11-04
IT8249087A0 (it) 1982-09-08
FI76071B (fi) 1988-05-31
DD211339A5 (de) 1984-07-11
FI823125A0 (fi) 1982-09-09
US4543360A (en) 1985-09-24
ATA337982A (de) 1985-04-15
JPS5857361A (ja) 1983-04-05
SE8205105D0 (sv) 1982-09-08
JPS62252766A (ja) 1987-11-04
ES8306722A1 (es) 1983-06-01
NL8203512A (nl) 1983-04-05
NO157173C (no) 1988-02-03
EG15840A (en) 1986-06-30
GB2111478A (en) 1983-07-06
NO157173B (no) 1987-10-26
DK157849B (da) 1990-02-26
YU202382A (en) 1985-06-30
FR2512446A1 (fr) 1983-03-11
ZA826637B (en) 1984-06-27
SE8205105L (sv) 1983-03-11
BE894332A (fr) 1983-03-07
JPS6237621B2 (fr) 1987-08-13
DK157849C (da) 1990-07-23
YU225584A (en) 1985-06-30
ES515590A0 (es) 1983-07-01
CA1185609A (fr) 1985-04-16
NO823061L (no) 1983-03-11

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