SE449101B - 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar - Google Patents

1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar

Info

Publication number
SE449101B
SE449101B SE8200679A SE8200679A SE449101B SE 449101 B SE449101 B SE 449101B SE 8200679 A SE8200679 A SE 8200679A SE 8200679 A SE8200679 A SE 8200679A SE 449101 B SE449101 B SE 449101B
Authority
SE
Sweden
Prior art keywords
benzyl
group
formula
reaction
dioxopiperazine
Prior art date
Application number
SE8200679A
Other languages
English (en)
Swedish (sv)
Other versions
SE8200679L (sv
Inventor
T Hori
C Yoshida
Y Kiba
R Takeno
J Nakano
J Nitta
S Kishimoto
S Murakami
H Tsuda
I Saikawa
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of SE8200679L publication Critical patent/SE8200679L/xx
Publication of SE449101B publication Critical patent/SE449101B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE8200679A 1981-02-06 1982-02-05 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar SE449101B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56015837A JPS57140783A (en) 1981-02-06 1981-02-06 1-benzyl-4-(4-(2-pyrimidinylamino)benzyl)-2, 3-dioxopiperazine derivative and its salt, their preparation, and carcinostatic agent containing the same

Publications (2)

Publication Number Publication Date
SE8200679L SE8200679L (sv) 1982-09-22
SE449101B true SE449101B (sv) 1987-04-06

Family

ID=11899943

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8200679A SE449101B (sv) 1981-02-06 1982-02-05 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar

Country Status (12)

Country Link
JP (1) JPS57140783A (es)
KR (1) KR880001105B1 (es)
AU (1) AU537512B2 (es)
BE (1) BE892032A (es)
CH (1) CH651036A5 (es)
DE (1) DE3204074A1 (es)
ES (2) ES8304970A1 (es)
FR (1) FR2499569A1 (es)
GB (1) GB2094296B (es)
IT (1) IT1154274B (es)
NL (1) NL8200451A (es)
SE (1) SE449101B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1244542C (zh) * 1996-12-24 2006-03-08 中外制药株式会社 具有nos抑制作用的芳香族胺衍生物
TWI803615B (zh) * 2018-04-11 2023-06-01 日商三菱瓦斯化學股份有限公司 二氰基烷及雙(胺甲基)烷之製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5618969A (en) * 1979-07-24 1981-02-23 Toyama Chem Co Ltd Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation

Also Published As

Publication number Publication date
AU8024082A (en) 1982-08-12
JPS6366319B2 (es) 1988-12-20
GB2094296A (en) 1982-09-15
FR2499569A1 (fr) 1982-08-13
DE3204074C2 (es) 1987-12-23
AU537512B2 (en) 1984-06-28
ES8402285A1 (es) 1984-01-16
ES509391A0 (es) 1983-03-16
IT1154274B (it) 1987-01-21
ES518304A0 (es) 1984-01-16
FR2499569B1 (es) 1985-02-22
CH651036A5 (de) 1985-08-30
BE892032A (fr) 1982-08-05
ES8304970A1 (es) 1983-03-16
NL8200451A (nl) 1982-09-01
KR880001105B1 (ko) 1988-06-29
KR830009090A (ko) 1983-12-17
JPS57140783A (en) 1982-08-31
IT8247729A0 (it) 1982-02-05
GB2094296B (en) 1985-02-13
SE8200679L (sv) 1982-09-22
DE3204074A1 (de) 1982-10-28

Similar Documents

Publication Publication Date Title
US4323570A (en) Substituted aminopyrimidines
SU1535379A3 (ru) Способ получени 5-замещенных 2,4-диаминопиримидинов или их кислотно-аддитивных солей
EP0371139B1 (en) 6-substituted acyclicpyrimidine nucleoside derivatives and antiviral agents containing same as active ingredients
DK160492B (da) Pyrimidinderivater, fremgangsmaader til fremstilling heraf samt farmaceutiske praeparater indeholdende disse derivater
NO126322B (es)
US5461060A (en) Pyrimidine derivatives and anti-viral agent containing the same as active ingredient thereof
KR100238562B1 (ko) 피페리딘 유도체 화합물
HU205917B (en) Process for producing 6-substituted pyrimidine derivatives and antiviral pharmaceutical compositions containing them as active components
US3962443A (en) Antibacterial pharmaceutical compositions and processes for preparation thereof
US3463850A (en) Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof
US3721664A (en) Preparation of 5-cytosine nucleosides
EP0449726A1 (en) Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient
HU187673B (en) Process for preparing 2-piperazino-pyrimidine derivatives
SE449101B (sv) 1-bensyl-4-/4-(2-pyrimidinylamino)bensyl/-2,3-dioxopiperazinderivat, forfarande for framstellning derav och karcinostatiska medel der de ingar
HU223477B1 (hu) Új azetidin-intermedier
US3839569A (en) Certain s-triazolo (4,3-a)quinolines as agents for control of plant pathogens
JPH0417957B2 (es)
DE69025084T2 (de) Hexitolderivate
EP0425669A1 (en) 1-amino-5-halogenouracils, process for their preparation, and central nervous system depressants containing same as active ingredient
US3729477A (en) Certain 4-(3-amino-2-hydroxypropoxy)-1,2,5-thiadiazole-3-carboxamides
JPH0696572B2 (ja) ピリドンカルボン酸誘導体、そのエステルおよびその塩
US4738960A (en) 1,3,4-Thiadiazole derivatives and pharmaceutical preparations useful as inhibitors for histamine-H2 receptors
JPH0635458B2 (ja) ピリドンカルボン酸誘導体、そのエステルおよびその塩
CA2040885A1 (en) Substituted benzhydryl 2-hydroxypropyl piperazine derivatives
WO1994003450A1 (en) Furylthiazole and their use as h2-receptor antagonists and antimicrobial agents

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8200679-2

Format of ref document f/p: F