NL8200451A - 1-benzyl-4-4-(2-pyrimidinylamino)benzyl-2,3-dioxopiperazinederivaten, zouten daarvan en werkwijzen voor het bereiden van deze derivaten en van farmaceutische preparaten die ze bevatten. - Google Patents

1-benzyl-4-4-(2-pyrimidinylamino)benzyl-2,3-dioxopiperazinederivaten, zouten daarvan en werkwijzen voor het bereiden van deze derivaten en van farmaceutische preparaten die ze bevatten. Download PDF

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Publication number
NL8200451A
NL8200451A NL8200451A NL8200451A NL8200451A NL 8200451 A NL8200451 A NL 8200451A NL 8200451 A NL8200451 A NL 8200451A NL 8200451 A NL8200451 A NL 8200451A NL 8200451 A NL8200451 A NL 8200451A
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NL
Netherlands
Prior art keywords
benzyl
formula
compound
group
dioxopiperazine
Prior art date
Application number
NL8200451A
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English (en)
Dutch (nl)
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of NL8200451A publication Critical patent/NL8200451A/nl

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL8200451A 1981-02-06 1982-02-05 1-benzyl-4-4-(2-pyrimidinylamino)benzyl-2,3-dioxopiperazinederivaten, zouten daarvan en werkwijzen voor het bereiden van deze derivaten en van farmaceutische preparaten die ze bevatten. NL8200451A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1583781 1981-02-06
JP56015837A JPS57140783A (en) 1981-02-06 1981-02-06 1-benzyl-4-(4-(2-pyrimidinylamino)benzyl)-2, 3-dioxopiperazine derivative and its salt, their preparation, and carcinostatic agent containing the same

Publications (1)

Publication Number Publication Date
NL8200451A true NL8200451A (nl) 1982-09-01

Family

ID=11899943

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8200451A NL8200451A (nl) 1981-02-06 1982-02-05 1-benzyl-4-4-(2-pyrimidinylamino)benzyl-2,3-dioxopiperazinederivaten, zouten daarvan en werkwijzen voor het bereiden van deze derivaten en van farmaceutische preparaten die ze bevatten.

Country Status (12)

Country Link
JP (1) JPS57140783A (es)
KR (1) KR880001105B1 (es)
AU (1) AU537512B2 (es)
BE (1) BE892032A (es)
CH (1) CH651036A5 (es)
DE (1) DE3204074A1 (es)
ES (2) ES8304970A1 (es)
FR (1) FR2499569A1 (es)
GB (1) GB2094296B (es)
IT (1) IT1154274B (es)
NL (1) NL8200451A (es)
SE (1) SE449101B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1244542C (zh) * 1996-12-24 2006-03-08 中外制药株式会社 具有nos抑制作用的芳香族胺衍生物
TWI803615B (zh) * 2018-04-11 2023-06-01 日商三菱瓦斯化學股份有限公司 二氰基烷及雙(胺甲基)烷之製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5618969A (en) * 1979-07-24 1981-02-23 Toyama Chem Co Ltd Novel 1-(4-aminobenzyl)-2,3-dioxopiperazine derivative, its acid addition salt, and their preparation

Also Published As

Publication number Publication date
AU8024082A (en) 1982-08-12
JPS6366319B2 (es) 1988-12-20
GB2094296A (en) 1982-09-15
FR2499569A1 (fr) 1982-08-13
DE3204074C2 (es) 1987-12-23
AU537512B2 (en) 1984-06-28
ES8402285A1 (es) 1984-01-16
ES509391A0 (es) 1983-03-16
IT1154274B (it) 1987-01-21
ES518304A0 (es) 1984-01-16
FR2499569B1 (es) 1985-02-22
CH651036A5 (de) 1985-08-30
BE892032A (fr) 1982-08-05
ES8304970A1 (es) 1983-03-16
KR880001105B1 (ko) 1988-06-29
KR830009090A (ko) 1983-12-17
SE449101B (sv) 1987-04-06
JPS57140783A (en) 1982-08-31
IT8247729A0 (it) 1982-02-05
GB2094296B (en) 1985-02-13
SE8200679L (sv) 1982-09-22
DE3204074A1 (de) 1982-10-28

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed