SE442400B - Forfarande for framstellning av nya 1-aryloxi-2-hydroxi-3-alkylenaminopropaner - Google Patents

Forfarande for framstellning av nya 1-aryloxi-2-hydroxi-3-alkylenaminopropaner

Info

Publication number
SE442400B
SE442400B SE7711168A SE7711168A SE442400B SE 442400 B SE442400 B SE 442400B SE 7711168 A SE7711168 A SE 7711168A SE 7711168 A SE7711168 A SE 7711168A SE 442400 B SE442400 B SE 442400B
Authority
SE
Sweden
Prior art keywords
alkylenaminopropanes
aryloxi
hydroxy
procedure
preparing new
Prior art date
Application number
SE7711168A
Other languages
English (en)
Swedish (sv)
Other versions
SE7711168L (sv
Inventor
H Koppe
A Mentrup
E-O Renth
K Schromm
W Hoefke
G Muacevic
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of SE7711168L publication Critical patent/SE7711168L/xx
Publication of SE442400B publication Critical patent/SE442400B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/181,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
SE7711168A 1976-10-05 1977-10-05 Forfarande for framstellning av nya 1-aryloxi-2-hydroxi-3-alkylenaminopropaner SE442400B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762644833 DE2644833A1 (de) 1976-10-05 1976-10-05 Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
SE7711168L SE7711168L (sv) 1978-05-18
SE442400B true SE442400B (sv) 1985-12-23

Family

ID=5989679

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7711168A SE442400B (sv) 1976-10-05 1977-10-05 Forfarande for framstellning av nya 1-aryloxi-2-hydroxi-3-alkylenaminopropaner

Country Status (33)

Country Link
US (7) US4256756A (nl)
JP (1) JPS5368775A (nl)
AT (15) AT361908B (nl)
AU (1) AU514600B2 (nl)
BE (1) BE859415A (nl)
BG (1) BG33153A3 (nl)
CA (4) CA1101859A (nl)
CS (1) CS197304B2 (nl)
DD (5) DD148050A5 (nl)
DE (1) DE2644833A1 (nl)
DK (1) DK439077A (nl)
ES (16) ES462868A1 (nl)
FI (1) FI69066C (nl)
FR (1) FR2394534A1 (nl)
GB (3) GB1592976A (nl)
GR (1) GR64229B (nl)
HK (1) HK19385A (nl)
HU (1) HU177173B (nl)
IE (3) IE46158B1 (nl)
IL (1) IL53043A (nl)
LU (1) LU78240A1 (nl)
MY (1) MY8500909A (nl)
NL (1) NL7710840A (nl)
NO (1) NO151411C (nl)
NZ (1) NZ185356A (nl)
PH (4) PH15763A (nl)
PL (1) PL113879B1 (nl)
PT (1) PT67107B (nl)
SE (1) SE442400B (nl)
SG (1) SG70884G (nl)
SU (1) SU665801A3 (nl)
YU (1) YU40484B (nl)
ZA (1) ZA775905B (nl)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404380A (en) * 1977-02-14 1983-09-13 Mead Johnson & Company Triazolopyrimidines
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
BE883069A (fr) * 1979-05-04 1980-08-18 Continental Pharma Derives de phenylethylamine, leur preparation et utilisation ainsi que composition contenant ces derives.
US4656168A (en) * 1980-12-23 1987-04-07 Merck & Co., Inc. (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation
US4349673A (en) * 1980-12-23 1982-09-14 Merck & Co., Inc. Benzoxazines
US4473501A (en) * 1981-05-04 1984-09-25 G. D. Searle & Co. Dihydro azino isoquinolines
US4379508A (en) * 1981-10-14 1983-04-12 Nestier Corporation Nesting tray with stacking keyed interlock
IT1193608B (it) * 1983-01-21 1988-07-21 Pierrel Spa Derivati di arilossipropanolamina,procedimento per la loro preparazione composizioni farmaceutiche che li contengono e loro impiego terapeutico
DE3324903A1 (de) * 1983-07-09 1985-01-17 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung substituierter ethylenharnstoffe sowie neue n-vinylethylenharnstoffe
GB8419797D0 (en) * 1984-08-03 1984-09-05 Beecham Group Plc Compounds
DE3807922A1 (de) * 1988-03-10 1989-09-21 Boehringer Mannheim Gmbh Substituierte heterocyclen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
TW203049B (nl) * 1990-04-13 1993-04-01 Yamanouchi Pharma Co Ltd
US6557907B2 (en) 1993-05-14 2003-05-06 William W. Rowley Polyethylene connectors
US6860524B1 (en) 1993-05-14 2005-03-01 William W. Rowley Polyolefin connectors
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US6848719B2 (en) 2001-09-06 2005-02-01 William W. Rowley Bendable polymer-lined water heater connector
MY143244A (en) 2002-11-26 2011-04-15 Smithkline Beecham Corp Calcilytic compounds
US20070117978A1 (en) * 2002-12-23 2007-05-24 Artesian Therapecutics, Inc Cardiotonic compounds with inhibitory activity against beta-adrenergic receptors and phosphodiesterase
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
EP1833480A2 (en) * 2004-11-30 2007-09-19 Artesian Therapeutics, Inc. Cardiotonic compounds with inhibitory activity against beta-adrenergic receptors and phosphodiesterase
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
PL3075401T3 (pl) * 2007-11-29 2024-08-19 Inolex Investment Corporation Środek konserwujący dla kompozycji kosmetycznych, toaletowych i farmaceutycznych
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑-磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL284529A (nl) * 1961-10-24
GB1066613A (en) * 1965-03-03 1967-04-26 Ici Ltd Naphthalene derivatives
GB1349358A (en) * 1969-11-28 1974-04-03 Teikoku Hormone Mfg Co Ltd Hydrogenation process
ZA71932B (en) * 1970-02-27 1971-10-27 Ici Ltd Organic compounds
BE787103A (fr) * 1971-08-04 1973-02-02 Pfizer Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant
US3894030A (en) * 1973-01-04 1975-07-08 Janssen Pharmaceutica Nv 1-{8 1-(2-Hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
US3818017A (en) * 1973-01-04 1974-06-18 Janssen Pharmaceutica Nv 1-{8 1-(2-hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
GB1456525A (en) * 1973-07-18 1976-11-24 Ici Ltd Process for the manufacture of alkanolamine derivatives
DE2503222A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH624395A5 (nl) * 1976-01-08 1981-07-31 Ciba Geigy Ag
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen

Also Published As

Publication number Publication date
GR64229B (en) 1980-02-14
FR2394534B1 (nl) 1982-04-30
AT363081B (de) 1981-07-10
ZA775905B (en) 1979-06-27
ES471803A1 (es) 1979-02-01
AT362363B (de) 1981-05-11
ATA56880A (de) 1980-09-15
ES471804A1 (es) 1979-02-01
AT361912B (de) 1981-04-10
DD143074A5 (de) 1980-07-30
ATA57580A (de) 1980-12-15
IE46158L (en) 1978-04-05
SU665801A3 (ru) 1979-05-30
IE822410L (en) 1978-04-05
SG70884G (en) 1985-04-04
ATA56980A (de) 1980-09-15
ES471800A1 (es) 1979-02-01
HK19385A (en) 1985-03-22
GB1592977A (en) 1981-07-15
YU236977A (en) 1983-01-21
IE46160B1 (en) 1983-03-09
US4255430A (en) 1981-03-10
ES471805A1 (es) 1979-02-01
ATA57480A (de) 1980-10-15
BE859415A (fr) 1978-04-05
PT67107A (de) 1977-11-01
FR2394534A1 (fr) 1979-01-12
MY8500909A (en) 1985-12-31
HU177173B (en) 1981-08-28
IE46158B1 (en) 1983-03-09
ES471798A1 (es) 1979-02-01
PH18363A (en) 1985-06-13
NO151411C (no) 1985-04-10
ES471794A1 (es) 1979-02-01
AT363082B (de) 1981-07-10
AT362364B (de) 1981-05-11
PL201286A1 (pl) 1978-12-04
US4296117A (en) 1981-10-20
ATA679377A (de) 1980-09-15
DD148050A5 (de) 1981-05-06
AT362365B (de) 1981-05-11
US4256756A (en) 1981-03-17
IL53043A (en) 1982-01-31
AU514600B2 (en) 1981-02-19
NO151411B (no) 1984-12-27
ES471797A1 (es) 1979-02-01
ES471807A1 (es) 1979-02-01
AT361911B (de) 1981-04-10
ATA58080A (de) 1981-04-15
JPS5368775A (en) 1978-06-19
AT364828B (de) 1981-11-25
ATA56780A (de) 1980-09-15
ATA57980A (de) 1980-12-15
AT361914B (de) 1981-04-10
ATA57180A (de) 1980-09-15
PH15763A (en) 1983-03-22
PH16053A (en) 1983-06-09
DD148051A5 (de) 1981-05-06
ATA57780A (de) 1980-12-15
US4212877A (en) 1980-07-15
DE2644833A1 (de) 1978-04-20
ES471795A1 (es) 1979-02-01
AT361913B (de) 1981-04-10
AT361915B (de) 1981-04-10
AT363080B (de) 1981-07-10
ES471808A1 (es) 1979-02-01
ATA57880A (de) 1980-10-15
ES471802A1 (es) 1979-02-01
ES471799A1 (es) 1979-02-01
US4381309A (en) 1983-04-26
BG33153A3 (en) 1982-12-15
US4604468A (en) 1986-08-05
ES471806A1 (es) 1979-02-01
DK439077A (da) 1978-04-06
IE46159B1 (en) 1983-03-09
NZ185356A (en) 1981-05-01
ES471801A1 (es) 1979-02-01
ATA57080A (de) 1980-09-15
AT362362B (de) 1981-05-11
ATA57280A (de) 1980-10-15
AT363079B (de) 1981-07-10
CA1126271A (en) 1982-06-22
FI772823A (fi) 1978-04-06
GB1592975A (en) 1981-07-15
ES471796A1 (es) 1979-02-01
FI69066C (fi) 1985-12-10
AT361908B (de) 1981-04-10
JPS6210988B2 (nl) 1987-03-10
CA1101859A (en) 1981-05-26
CA1125751A (en) 1982-06-15
AU2933377A (en) 1979-04-12
DD148052A5 (de) 1981-05-06
IL53043A0 (en) 1977-12-30
NO773384L (no) 1978-04-06
YU40484B (en) 1986-02-28
GB1592976A (en) 1981-07-15
PH19028A (en) 1985-12-06
ES462868A1 (es) 1978-12-16
NL7710840A (nl) 1978-04-07
PT67107B (de) 1980-04-07
US4343800A (en) 1982-08-10
IE822409L (en) 1978-04-05
DD134642A5 (de) 1979-03-14
CS197304B2 (en) 1980-04-30
CA1127643A (en) 1982-07-13
SE7711168L (sv) 1978-05-18
PL113879B1 (en) 1981-01-31
FI69066B (fi) 1985-08-30
ATA57380A (de) 1980-10-15
ATA57680A (de) 1980-12-15
LU78240A1 (nl) 1979-02-02

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