ES471805A1 - Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos - Google Patents

Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos

Info

Publication number
ES471805A1
ES471805A1 ES471805A ES471805A ES471805A1 ES 471805 A1 ES471805 A1 ES 471805A1 ES 471805 A ES471805 A ES 471805A ES 471805 A ES471805 A ES 471805A ES 471805 A1 ES471805 A1 ES 471805A1
Authority
ES
Spain
Prior art keywords
salts
benzimidazolin
propanes
aryloxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471805A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES471805A1 publication Critical patent/ES471805A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)

Abstract

Procedimiento para la preparación de nuevos 1-ariloxi-2-hidroxi-3-alcohilenaminopropanos, racémicos u ópticamente activos de la fórmula general I **(Fórmula)** en donde R1 significa un átomo de hidrógeno o de halógeno, un grupo trifluorometilo o un grupo nitro, un grupo alcohilo recto o ramificado con 1 a 8 átomos de carbono, un grupo alcoxi recto o ramificado con 1 a 4 átomos de carbono, un grupo aloxialcohilo con 2 a 8 átomos de carbono, un grupo alquenilo o alquinilo con 2 a 5 átomos de carbono, un grupo alqueniloxi o alquiniloxi con 3 a 6 átomos de carbono, un grupo cicloalcohilo o cicloalcoxi (eventualmente) puenteado y/o insaturado con 3 a 12 átomos de carbono, un radical con la fórmula parcial (CH2)X-A'', en donde x significa cero o un número entero de 1 a 3, y A'' significa un grupo ciano, amino, carboxamido o hidroxi.
ES471805A 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos Expired ES471805A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762644833 DE2644833A1 (de) 1976-10-05 1976-10-05 Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES471805A1 true ES471805A1 (es) 1979-02-01

Family

ID=5989679

Family Applications (16)

Application Number Title Priority Date Filing Date
ES462868A Expired ES462868A1 (es) 1976-10-05 1977-10-04 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3-alcohilena minopropanos, racemicos y opticmente ac- tivos.
ES471802A Expired ES471802A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos opticamente acti- vos
ES471800A Expired ES471800A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471795A Expired ES471795A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471799A Expired ES471799A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471804A Expired ES471804A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos
ES471805A Expired ES471805A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos
ES471803A Expired ES471803A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos
ES471794A Expired ES471794A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471801A Expired ES471801A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471807A Expired ES471807A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos derivados de fe-nilimidozolidinona
ES471796A Expired ES471796A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471808A Expired ES471808A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevas azetidinoles
ES471798A Expired ES471798A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471806A Expired ES471806A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos
ES471797A Expired ES471797A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos

Family Applications Before (6)

Application Number Title Priority Date Filing Date
ES462868A Expired ES462868A1 (es) 1976-10-05 1977-10-04 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3-alcohilena minopropanos, racemicos y opticmente ac- tivos.
ES471802A Expired ES471802A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos opticamente acti- vos
ES471800A Expired ES471800A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471795A Expired ES471795A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471799A Expired ES471799A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471804A Expired ES471804A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos

Family Applications After (9)

Application Number Title Priority Date Filing Date
ES471803A Expired ES471803A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos
ES471794A Expired ES471794A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471801A Expired ES471801A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471807A Expired ES471807A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos derivados de fe-nilimidozolidinona
ES471796A Expired ES471796A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471808A Expired ES471808A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevas azetidinoles
ES471798A Expired ES471798A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES471806A Expired ES471806A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 - alcohilenaminopropanos, racemicos u opticamente activos
ES471797A Expired ES471797A1 (es) 1976-10-05 1978-07-17 Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos

Country Status (33)

Country Link
US (7) US4212877A (es)
JP (1) JPS5368775A (es)
AT (15) AT361908B (es)
AU (1) AU514600B2 (es)
BE (1) BE859415A (es)
BG (1) BG33153A3 (es)
CA (4) CA1101859A (es)
CS (1) CS197304B2 (es)
DD (5) DD143074A5 (es)
DE (1) DE2644833A1 (es)
DK (1) DK439077A (es)
ES (16) ES462868A1 (es)
FI (1) FI69066C (es)
FR (1) FR2394534A1 (es)
GB (3) GB1592976A (es)
GR (1) GR64229B (es)
HK (1) HK19385A (es)
HU (1) HU177173B (es)
IE (3) IE46159B1 (es)
IL (1) IL53043A (es)
LU (1) LU78240A1 (es)
MY (1) MY8500909A (es)
NL (1) NL7710840A (es)
NO (1) NO151411C (es)
NZ (1) NZ185356A (es)
PH (4) PH15763A (es)
PL (1) PL113879B1 (es)
PT (1) PT67107B (es)
SE (1) SE442400B (es)
SG (1) SG70884G (es)
SU (1) SU665801A3 (es)
YU (1) YU40484B (es)
ZA (1) ZA775905B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404380A (en) * 1977-02-14 1983-09-13 Mead Johnson & Company Triazolopyrimidines
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
FR2455572B1 (fr) * 1979-05-04 1986-07-25 Continental Pharma Derives de phenylethylamine, leur preparation et utilisation dans le traitement des affections cardiovasculaires, et compositions les contenant
US4656168A (en) * 1980-12-23 1987-04-07 Merck & Co., Inc. (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation
US4349673A (en) * 1980-12-23 1982-09-14 Merck & Co., Inc. Benzoxazines
US4473501A (en) * 1981-05-04 1984-09-25 G. D. Searle & Co. Dihydro azino isoquinolines
US4379508A (en) * 1981-10-14 1983-04-12 Nestier Corporation Nesting tray with stacking keyed interlock
IT1193608B (it) * 1983-01-21 1988-07-21 Pierrel Spa Derivati di arilossipropanolamina,procedimento per la loro preparazione composizioni farmaceutiche che li contengono e loro impiego terapeutico
DE3324903A1 (de) * 1983-07-09 1985-01-17 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung substituierter ethylenharnstoffe sowie neue n-vinylethylenharnstoffe
GB8419797D0 (en) * 1984-08-03 1984-09-05 Beecham Group Plc Compounds
DE3807922A1 (de) * 1988-03-10 1989-09-21 Boehringer Mannheim Gmbh Substituierte heterocyclen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
TW203049B (es) * 1990-04-13 1993-04-01 Yamanouchi Pharma Co Ltd
US6860524B1 (en) 1993-05-14 2005-03-01 William W. Rowley Polyolefin connectors
US6557907B2 (en) 1993-05-14 2003-05-06 William W. Rowley Polyethylene connectors
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US6848719B2 (en) 2001-09-06 2005-02-01 William W. Rowley Bendable polymer-lined water heater connector
UY28089A1 (es) 2002-11-26 2004-06-30 Smithkline Beecham Corp Compuestos calciliticos
JP2006513222A (ja) * 2002-12-23 2006-04-20 アルテシアン セラピューティック，インコーポレイティド アドレナリン性β受容体およびホスホジエステラーゼに対する抑制活性を有する強心性化合物
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
US20080255134A1 (en) * 2004-11-30 2008-10-16 Artesian Therapeutics, Inc. Cardiotonic Compounds With Inhibitory Activity Against Beta-Adrenergic Receptors And Phosphodiesterase
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
US8993641B2 (en) * 2007-11-29 2015-03-31 Innolex Investment Corporation Preservation of cosmetics, toiletry and pharmaceutical compositions
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL284529A (es) * 1961-10-24
GB1066613A (en) * 1965-03-03 1967-04-26 Ici Ltd Naphthalene derivatives
DE2065365C3 (de) * 1969-11-28 1982-05-06 Teikoku Hormone Mfg. Co. Ltd., Tokyo 1,3-disubstituierte Azetidine sowie Verfahren zu deren Herstellung und ihre Anwendung
ZA71932B (en) * 1970-02-27 1971-10-27 Ici Ltd Organic compounds
BE787103A (fr) * 1971-08-04 1973-02-02 Pfizer Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant
US3894030A (en) * 1973-01-04 1975-07-08 Janssen Pharmaceutica Nv 1-{8 1-(2-Hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
US3818017A (en) * 1973-01-04 1974-06-18 Janssen Pharmaceutica Nv 1-{8 1-(2-hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
GB1456525A (en) * 1973-07-18 1976-11-24 Ici Ltd Process for the manufacture of alkanolamine derivatives
DE2503222A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH624395A5 (es) * 1976-01-08 1981-07-31 Ciba Geigy Ag
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen

Also Published As

Publication number Publication date
AT361915B (de) 1981-04-10
BG33153A3 (en) 1982-12-15
ES471798A1 (es) 1979-02-01
AT362362B (de) 1981-05-11
IE822409L (en) 1978-04-05
US4212877A (en) 1980-07-15
US4296117A (en) 1981-10-20
ATA56780A (de) 1980-09-15
AT361912B (de) 1981-04-10
AT361913B (de) 1981-04-10
GB1592976A (en) 1981-07-15
ATA57380A (de) 1980-10-15
BE859415A (fr) 1978-04-05
ATA57880A (de) 1980-10-15
GB1592977A (en) 1981-07-15
ATA679377A (de) 1980-09-15
MY8500909A (en) 1985-12-31
CA1101859A (en) 1981-05-26
IE46158B1 (en) 1983-03-09
ATA57180A (de) 1980-09-15
ZA775905B (en) 1979-06-27
SE7711168L (sv) 1978-05-18
IL53043A0 (en) 1977-12-30
AU514600B2 (en) 1981-02-19
AT363082B (de) 1981-07-10
ES471807A1 (es) 1979-02-01
ATA57080A (de) 1980-09-15
NL7710840A (nl) 1978-04-07
DD148052A5 (de) 1981-05-06
FI69066B (fi) 1985-08-30
AT361911B (de) 1981-04-10
DD148050A5 (de) 1981-05-06
FI772823A (fi) 1978-04-06
FI69066C (fi) 1985-12-10
IE46160B1 (en) 1983-03-09
ATA56880A (de) 1980-09-15
AT362364B (de) 1981-05-11
ATA57580A (de) 1980-12-15
PL201286A1 (pl) 1978-12-04
ES471796A1 (es) 1979-02-01
AT361914B (de) 1981-04-10
ATA57280A (de) 1980-10-15
IE46159B1 (en) 1983-03-09
ES471799A1 (es) 1979-02-01
HK19385A (en) 1985-03-22
ES471800A1 (es) 1979-02-01
SE442400B (sv) 1985-12-23
PH16053A (en) 1983-06-09
ATA57980A (de) 1980-12-15
ES471797A1 (es) 1979-02-01
AT363081B (de) 1981-07-10
ATA58080A (de) 1981-04-15
GR64229B (en) 1980-02-14
PH18363A (en) 1985-06-13
DE2644833A1 (de) 1978-04-20
AT362365B (de) 1981-05-11
AU2933377A (en) 1979-04-12
AT363080B (de) 1981-07-10
LU78240A1 (es) 1979-02-02
US4604468A (en) 1986-08-05
IE822410L (en) 1978-04-05
YU40484B (en) 1986-02-28
DK439077A (da) 1978-04-06
ES462868A1 (es) 1978-12-16
SG70884G (en) 1985-04-04
DD134642A5 (de) 1979-03-14
CA1125751A (en) 1982-06-15
JPS6210988B2 (es) 1987-03-10
DD148051A5 (de) 1981-05-06
ATA56980A (de) 1980-09-15
AT364828B (de) 1981-11-25
PL113879B1 (en) 1981-01-31
YU236977A (en) 1983-01-21
FR2394534A1 (fr) 1979-01-12
CS197304B2 (en) 1980-04-30
ES471801A1 (es) 1979-02-01
ATA57480A (de) 1980-10-15
GB1592975A (en) 1981-07-15
ATA57780A (de) 1980-12-15
CA1127643A (en) 1982-07-13
AT363079B (de) 1981-07-10
CA1126271A (en) 1982-06-22
US4343800A (en) 1982-08-10
US4256756A (en) 1981-03-17
AT362363B (de) 1981-05-11
PH15763A (en) 1983-03-22
NO151411C (no) 1985-04-10
ES471808A1 (es) 1979-02-01
FR2394534B1 (es) 1982-04-30
NO773384L (no) 1978-04-06
ES471803A1 (es) 1979-02-01
JPS5368775A (en) 1978-06-19
ES471806A1 (es) 1979-02-01
ES471795A1 (es) 1979-02-01
ES471802A1 (es) 1979-02-01
NZ185356A (en) 1981-05-01
HU177173B (en) 1981-08-28
PH19028A (en) 1985-12-06
PT67107B (de) 1980-04-07
NO151411B (no) 1984-12-27
ES471804A1 (es) 1979-02-01
IL53043A (en) 1982-01-31
PT67107A (de) 1977-11-01
SU665801A3 (ru) 1979-05-30
ES471794A1 (es) 1979-02-01
US4255430A (en) 1981-03-10
US4381309A (en) 1983-04-26
ATA57680A (de) 1980-12-15
AT361908B (de) 1981-04-10
IE46158L (en) 1978-04-05
DD143074A5 (de) 1980-07-30

Similar Documents

Publication Publication Date Title
ES471801A1 (es) Procedimiento para la preparacion de nuevos 1-ariloxi-2-hi- droxi-3 alcohilenaminopropanos, racemicos u opticamente ac- tivos
ES425084A2 (es) Procedimiento para la preparacion de aminoalcoholes.
ES462658A1 (es) Un procedimiento para la preparacion de un pentapeptido.
ES8200011A1 (es) Procedimiento de preparacion de una composicion farmaceuticaen particular psicotropa.
SE7605361L (sv) Sett att framstella nya n-substituerade fenylpiperazinderivat
ES437423A1 (es) Procedimiento para la preparacion de nuevas piridobenzodia- zepinonas.
DE3269187D1 (en) Heterocyclic compounds, their preparation and use
ES449765A1 (es) Procedimiento para la preparacion de nuevas homoftalimidas.
ES8200648A2 (es) Procedimiento de preparacion de compuestos opacificantes para radiografia y similares
ES448696A1 (es) Procedimiento para la preparacion de 4-fenil-imidazolinas sustituidas.
ES8705426A1 (es) Un procedimiento para la preparacion de un derivado de piperazina.
GB2022583A (en) New ionic polyiodo benzene derivatives useful as X-ray contrast media

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103