SE433353B - Analogiforfarande for framstellning av pyrido/1,2-a/pyrimidiner med antiflogistisk och koagulationshemmande verkan - Google Patents

Analogiforfarande for framstellning av pyrido/1,2-a/pyrimidiner med antiflogistisk och koagulationshemmande verkan

Info

Publication number
SE433353B
SE433353B SE7613140A SE7613140A SE433353B SE 433353 B SE433353 B SE 433353B SE 7613140 A SE7613140 A SE 7613140A SE 7613140 A SE7613140 A SE 7613140A SE 433353 B SE433353 B SE 433353B
Authority
SE
Sweden
Prior art keywords
antiflogistic
pyrido
pyrimidines
coagulating
preparation
Prior art date
Application number
SE7613140A
Other languages
English (en)
Other versions
SE7613140L (sv
Inventor
Z Meszaros
J Knoll
P Szentmiklosi
I Hermecz
A Horvath
S Virag
A David
L Vasvari
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of SE7613140L publication Critical patent/SE7613140L/sv
Publication of SE433353B publication Critical patent/SE433353B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7613140A 1975-11-27 1976-11-24 Analogiforfarande for framstellning av pyrido/1,2-a/pyrimidiner med antiflogistisk och koagulationshemmande verkan SE433353B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75CI1623A HU173438B (hu) 1975-11-27 1975-11-27 Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom

Publications (2)

Publication Number Publication Date
SE7613140L SE7613140L (sv) 1977-05-28
SE433353B true SE433353B (sv) 1984-05-21

Family

ID=10994587

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7613140A SE433353B (sv) 1975-11-27 1976-11-24 Analogiforfarande for framstellning av pyrido/1,2-a/pyrimidiner med antiflogistisk och koagulationshemmande verkan

Country Status (28)

Country Link
US (2) US4460771A (sv)
JP (1) JPS5914033B2 (sv)
AT (1) AT359506B (sv)
AU (1) AU512256B2 (sv)
BE (1) BE848868A (sv)
BG (1) BG31226A4 (sv)
CA (1) CA1088531A (sv)
CH (2) CH630378A5 (sv)
CS (1) CS203135B2 (sv)
DD (1) DD130431A5 (sv)
DE (1) DE2653257A1 (sv)
DK (1) DK153150C (sv)
EG (1) EG12495A (sv)
ES (1) ES453690A1 (sv)
FI (1) FI62085C (sv)
FR (1) FR2332755A1 (sv)
GB (1) GB1531963A (sv)
GR (1) GR61820B (sv)
HU (1) HU173438B (sv)
IL (1) IL50930A (sv)
IN (1) IN148945B (sv)
MX (1) MX5178E (sv)
NL (1) NL188948C (sv)
PL (1) PL109657B1 (sv)
RO (2) RO79705A (sv)
SE (1) SE433353B (sv)
SU (2) SU664565A3 (sv)
YU (2) YU289076A (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
HU186607B (en) * 1982-03-31 1985-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing pharmaceutical composition with synergetic antiinflammatory activity
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US4772475A (en) * 1985-03-08 1988-09-20 Yamanouchi Pharmaceutical Co., Ltd. Controlled-release multiple units pharmaceutical formulation
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
HU201551B (en) * 1988-02-03 1990-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-carboxylic acid amide derivatives and pharmaceutical compositions comprising same
MY125533A (en) 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
NZ538029A (en) * 2002-07-09 2006-08-31 Actelion Pharmaceuticals Ltd 7,8,9,10-tetrahydro-6H-azepino, 6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2H-pyrrolo[2,1-b]-quinazolinone derivatives
US7772232B2 (en) * 2004-04-15 2010-08-10 Bristol-Myers Squibb Company Quinazolinyl compounds as inhibitors of potassium channel function
GB2423928B (en) * 2004-11-16 2008-04-09 Efflux Technology Inc Methods and compositions for treating pain

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT299212B (de) * 1966-11-02 1972-06-12 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
US3642797A (en) * 1968-06-10 1972-02-15 Sterling Drug Inc 4h-pyrido(1 2-a)pyrimidin-4-ones
HU168014B (sv) * 1973-03-30 1976-02-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU168541B (sv) * 1973-11-24 1976-05-28
US4022897A (en) * 1974-03-04 1977-05-10 E. R. Squibb & Sons, Inc. CNS active compounds
US3960863A (en) * 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
US4066766A (en) * 1975-03-03 1978-01-03 Pfizer Inc. 1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents
HU174693B (hu) * 1976-02-12 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija kondensirovannykh proizvodnykh pirimidina
US4122274A (en) * 1977-05-25 1978-10-24 Bristol-Myers Company 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents

Also Published As

Publication number Publication date
NL188948B (nl) 1992-06-16
FI763401A (sv) 1977-05-28
ES453690A1 (es) 1977-12-01
EG12495A (en) 1980-12-31
YU147583A (en) 1986-06-30
FI62085B (fi) 1982-07-30
JPS5268198A (en) 1977-06-06
DE2653257C2 (sv) 1989-04-20
US4472398A (en) 1984-09-18
RO79705A (ro) 1982-08-17
BG31226A4 (en) 1981-11-16
IL50930A0 (en) 1977-01-31
FR2332755B1 (sv) 1978-12-22
FI62085C (fi) 1982-11-10
ATA873576A (de) 1980-04-15
RO73522A (ro) 1981-11-04
MX5178E (es) 1983-04-20
IN148945B (sv) 1981-07-25
IL50930A (en) 1981-06-29
BE848868A (fr) 1977-03-16
HU173438B (hu) 1979-05-28
SE7613140L (sv) 1977-05-28
SU664565A3 (ru) 1979-05-25
JPS5914033B2 (ja) 1984-04-02
GR61820B (en) 1979-01-22
YU289076A (en) 1983-12-31
DE2653257A1 (de) 1977-06-02
DK534076A (da) 1977-05-28
US4460771A (en) 1984-07-17
CH630378A5 (de) 1982-06-15
AT359506B (de) 1980-11-10
PL109657B1 (en) 1980-06-30
DD130431A5 (de) 1978-03-29
SU698532A3 (ru) 1979-11-15
CS203135B2 (en) 1981-02-27
FR2332755A1 (fr) 1977-06-24
DK153150C (da) 1988-10-24
CH630379A5 (de) 1982-06-15
NL7613140A (nl) 1977-06-01
AU512256B2 (en) 1980-10-02
GB1531963A (en) 1978-11-15
AU1975976A (en) 1978-05-25
CA1088531A (en) 1980-10-28
NL188948C (nl) 1992-11-16
DK153150B (da) 1988-06-20

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