BE848868A - Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes, - Google Patents

Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes,

Info

Publication number
BE848868A
BE848868A BE172806A BE172806A BE848868A BE 848868 A BE848868 A BE 848868A BE 172806 A BE172806 A BE 172806A BE 172806 A BE172806 A BE 172806A BE 848868 A BE848868 A BE 848868A
Authority
BE
Belgium
Prior art keywords
antiphlogistic
pyrimidine derivatives
anticoagulant properties
condensed pyrimidine
new condensed
Prior art date
Application number
BE172806A
Other languages
English (en)
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of BE848868A publication Critical patent/BE848868A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE172806A 1975-11-27 1976-11-29 Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes, BE848868A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75CI1623A HU173438B (hu) 1975-11-27 1975-11-27 Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom

Publications (1)

Publication Number Publication Date
BE848868A true BE848868A (fr) 1977-03-16

Family

ID=10994587

Family Applications (1)

Application Number Title Priority Date Filing Date
BE172806A BE848868A (fr) 1975-11-27 1976-11-29 Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes,

Country Status (28)

Country Link
US (2) US4460771A (fr)
JP (1) JPS5914033B2 (fr)
AT (1) AT359506B (fr)
AU (1) AU512256B2 (fr)
BE (1) BE848868A (fr)
BG (1) BG31226A4 (fr)
CA (1) CA1088531A (fr)
CH (2) CH630378A5 (fr)
CS (1) CS203135B2 (fr)
DD (1) DD130431A5 (fr)
DE (1) DE2653257A1 (fr)
DK (1) DK153150C (fr)
EG (1) EG12495A (fr)
ES (1) ES453690A1 (fr)
FI (1) FI62085C (fr)
FR (1) FR2332755A1 (fr)
GB (1) GB1531963A (fr)
GR (1) GR61820B (fr)
HU (1) HU173438B (fr)
IL (1) IL50930A (fr)
IN (1) IN148945B (fr)
MX (1) MX5178E (fr)
NL (1) NL188948C (fr)
PL (1) PL109657B1 (fr)
RO (2) RO79705A (fr)
SE (1) SE433353B (fr)
SU (2) SU664565A3 (fr)
YU (2) YU289076A (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
HU186607B (en) * 1982-03-31 1985-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing pharmaceutical composition with synergetic antiinflammatory activity
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US4772475A (en) * 1985-03-08 1988-09-20 Yamanouchi Pharmaceutical Co., Ltd. Controlled-release multiple units pharmaceutical formulation
HU201551B (en) * 1988-02-03 1990-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-carboxylic acid amide derivatives and pharmaceutical compositions comprising same
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
MY125533A (en) * 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
JP4498922B2 (ja) * 2002-07-09 2010-07-07 アクテリオン ファーマシューティカルズ リミテッド ７，８，９，１０−テトラヒドロ−６Ｈ−アゼピノ、６，７，８，９−テトラヒドロ−ピリドおよび２，３−ジヒドロ−２Ｈ−ピロロ［２，１−ｂ］−キナゾリノン誘導体
US7772232B2 (en) * 2004-04-15 2010-08-10 Bristol-Myers Squibb Company Quinazolinyl compounds as inhibitors of potassium channel function
US20060111308A1 (en) * 2004-11-16 2006-05-25 Wendye Robbins Methods and compositions for therapeutic treatment

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538494A (de) * 1966-11-02 1973-06-30 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung neuer Homopyrimidazol-Derivate
US3642797A (en) * 1968-06-10 1972-02-15 Sterling Drug Inc 4h-pyrido(1 2-a)pyrimidin-4-ones
HU168014B (fr) * 1973-03-30 1976-02-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU168541B (fr) * 1973-11-24 1976-05-28
US4022897A (en) * 1974-03-04 1977-05-10 E. R. Squibb & Sons, Inc. CNS active compounds
US3960863A (en) * 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
US4066766A (en) * 1975-03-03 1978-01-03 Pfizer Inc. 1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents
HU174693B (hu) * 1976-02-12 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija kondensirovannykh proizvodnykh pirimidina
US4122274A (en) * 1977-05-25 1978-10-24 Bristol-Myers Company 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents

Also Published As

Publication number Publication date
GB1531963A (en) 1978-11-15
HU173438B (hu) 1979-05-28
NL188948C (nl) 1992-11-16
CH630378A5 (de) 1982-06-15
NL188948B (nl) 1992-06-16
DD130431A5 (de) 1978-03-29
FI62085C (fi) 1982-11-10
JPS5268198A (en) 1977-06-06
YU147583A (en) 1986-06-30
AU1975976A (en) 1978-05-25
IL50930A (en) 1981-06-29
IN148945B (fr) 1981-07-25
JPS5914033B2 (ja) 1984-04-02
BG31226A4 (en) 1981-11-16
CH630379A5 (de) 1982-06-15
SU664565A3 (ru) 1979-05-25
EG12495A (en) 1980-12-31
AT359506B (de) 1980-11-10
MX5178E (es) 1983-04-20
SU698532A3 (ru) 1979-11-15
US4460771A (en) 1984-07-17
DK153150B (da) 1988-06-20
ES453690A1 (es) 1977-12-01
FI62085B (fi) 1982-07-30
CA1088531A (fr) 1980-10-28
FI763401A (fr) 1977-05-28
DK534076A (da) 1977-05-28
FR2332755A1 (fr) 1977-06-24
DE2653257A1 (de) 1977-06-02
CS203135B2 (en) 1981-02-27
AU512256B2 (en) 1980-10-02
YU289076A (en) 1983-12-31
DK153150C (da) 1988-10-24
ATA873576A (de) 1980-04-15
SE7613140L (sv) 1977-05-28
DE2653257C2 (fr) 1989-04-20
NL7613140A (nl) 1977-06-01
RO79705A (fr) 1982-08-17
FR2332755B1 (fr) 1978-12-22
US4472398A (en) 1984-09-18
PL109657B1 (en) 1980-06-30
IL50930A0 (en) 1977-01-31
SE433353B (sv) 1984-05-21
GR61820B (en) 1979-01-22
RO73522A (fr) 1981-11-04

Similar Documents

Publication Publication Date Title
BE859012A (fr) Derives de 4-n-acylfortimicines b, leur preparation et leur application
FR2341576A1 (fr) 2-piperazinyl-6,7-dimethoxyquinazolines et leur application pharmacologique
BE848868A (fr) Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes,
IT7919614A0 (it) Derivati della piridina, loro preparazione e loro impiego.
FR2349579A1 (fr) Derives de 1,2-dihydronaphtalene et leur procede de preparation
BE860736A (fr) Derives de piperidine et leur preparation.
FR2345150A2 (fr) Nouveaux derives de la thienopyridine, et leur application
BE865705A (fr) Nouveaux derives de prostane, leur procede de preparation et leur utilisation
FR2331583A1 (fr) Terpolymere polyamide et sa preparation
FR2335567A1 (fr) Colorants disazoiques, leur obtention et leur application
NL7704413A (nl) Bouwset, bestaande uit aan een zijde open holle bouwstenen.
SE7607174L (sv) Kolofoniumdisperison med forbettrad stabilitet
FR2353537A1 (fr) Nouveaux derives aminomethylazoliques, leur procede de preparation et l
FR2317930A1 (fr) Nouveaux derives d'apovincaminol, leur procede de preparation et leur application
BE861500R (fr) Nouveaux derives d'isoxazoles, leur procde de preparation et leur applications
BE845209A (fr) 1, 1-dichloro-4-methyl-3-hydroxy-pentene-(1) et sa preparation
BE845612A (fr) Derives de tetrazole-5-carboxamide et leur preparation
BE861502R (fr) Nouveaux derives d'isoxazoles, leur procde de preparation et leurs applications
DK166393C (da) Fremgangsmaade til fremstilling af vandige organekstrakter med et heparinindhold paa mindst 120 ie/ml
IT8020503A0 (it) Derivati della 1,1'-bifenil-2-ilalchilammina ad azione farmaceutica.
IT1142099B (it) Derivati della 1,2-diidro-5-(piridinil)nicotinamide, e loro preparazione
BE843395A (fr) Sulfonamido-salicylaldehydes, leur obtention et leur application
FR2316292A1 (fr) Colorants disazoiques, leur obtention et leur application
IT8025425A0 (it) Pantalone da sci.
BE837595A (fr) Nouveaux derives de nitroimidazole et leur preparation

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.

Effective date: 19941130