BE848868A - Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes, - Google Patents

Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes,

Info

Publication number
BE848868A
BE848868A BE172806A BE172806A BE848868A BE 848868 A BE848868 A BE 848868A BE 172806 A BE172806 A BE 172806A BE 172806 A BE172806 A BE 172806A BE 848868 A BE848868 A BE 848868A
Authority
BE
Belgium
Prior art keywords
antiphlogistic
pyrimidine derivatives
anticoagulant properties
condensed pyrimidine
new condensed
Prior art date
Application number
BE172806A
Other languages
English (en)
French (fr)
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of BE848868A publication Critical patent/BE848868A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
BE172806A 1975-11-27 1976-11-29 Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes, BE848868A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75CI1623A HU173438B (hu) 1975-11-27 1975-11-27 Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom

Publications (1)

Publication Number Publication Date
BE848868A true BE848868A (fr) 1977-03-16

Family

ID=10994587

Family Applications (1)

Application Number Title Priority Date Filing Date
BE172806A BE848868A (fr) 1975-11-27 1976-11-29 Nouveaux derives de pyrimidine condenses a proprietes antiphlogistiques et anticoagulantes,

Country Status (28)

Country Link
US (2) US4460771A (xx)
JP (1) JPS5914033B2 (xx)
AT (1) AT359506B (xx)
AU (1) AU512256B2 (xx)
BE (1) BE848868A (xx)
BG (1) BG31227A4 (xx)
CA (1) CA1088531A (xx)
CH (2) CH630378A5 (xx)
CS (1) CS203135B2 (xx)
DD (1) DD130431A5 (xx)
DE (1) DE2653257A1 (xx)
DK (1) DK153150C (xx)
EG (1) EG12495A (xx)
ES (1) ES453690A1 (xx)
FI (1) FI62085C (xx)
FR (1) FR2332755A1 (xx)
GB (1) GB1531963A (xx)
GR (1) GR61820B (xx)
HU (1) HU173438B (xx)
IL (1) IL50930A (xx)
IN (1) IN148945B (xx)
MX (1) MX5178E (xx)
NL (1) NL188948C (xx)
PL (1) PL109657B1 (xx)
RO (2) RO79705A (xx)
SE (1) SE433353B (xx)
SU (2) SU664565A3 (xx)
YU (2) YU289076A (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU180701B (en) * 1977-12-29 1983-04-29 Chinoin Gyogyszer Es Vegyeszet Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents
US4342870A (en) * 1980-03-28 1982-08-03 Janssen Pharmaceutica N.V. Novel 3-(1-piperidinylalkyl)-4H-pyrido[1,2-a]pyrimidin-4-one derivatives
HU183408B (en) * 1981-04-28 1984-05-28 Chinoin Gyogyszer Es Vegyeszet Process for producing oral ratard pharmaceutical compositions
HU186607B (en) * 1982-03-31 1985-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing pharmaceutical composition with synergetic antiinflammatory activity
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US4772475A (en) * 1985-03-08 1988-09-20 Yamanouchi Pharmaceutical Co., Ltd. Controlled-release multiple units pharmaceutical formulation
US5252572A (en) * 1988-02-03 1993-10-12 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
HU201551B (en) * 1988-02-03 1990-11-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 4-oxo-4h-pyrido(1,2-a)pyrimidine-3-carboxylic acid amide derivatives and pharmaceutical compositions comprising same
MY125533A (en) 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
PL373223A1 (en) * 2002-07-09 2005-08-22 Actelion Pharmaceuticals Ltd. 7,8,9,10-tetrahydro-6h-azepino, 6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2h-pyrrolo[2,1-b]-quinazolinone derivatives
US7772232B2 (en) * 2004-04-15 2010-08-10 Bristol-Myers Squibb Company Quinazolinyl compounds as inhibitors of potassium channel function
GB2423928B (en) * 2004-11-16 2008-04-09 Efflux Technology Inc Methods and compositions for treating pain

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT294107B (de) * 1966-11-02 1971-11-10 Chinoin Gyogyszer Es Vegyeszet Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
US3642797A (en) * 1968-06-10 1972-02-15 Sterling Drug Inc 4h-pyrido(1 2-a)pyrimidin-4-ones
HU168014B (xx) * 1973-03-30 1976-02-28
US4209622A (en) * 1973-03-30 1980-06-24 Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt. 3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU168541B (xx) * 1973-11-24 1976-05-28
US4022897A (en) * 1974-03-04 1977-05-10 E. R. Squibb & Sons, Inc. CNS active compounds
US3960863A (en) * 1974-06-25 1976-06-01 Sankyo Company Limited Pyrido[1,2-a]pyrimidinone derivatives
US4066766A (en) * 1975-03-03 1978-01-03 Pfizer Inc. 1-Oxo-6-substituted pyrimido [1,2-a]quinoline-2-carboxylic acids and derivatives thereof and their use as antiallergy agents
HU174693B (hu) * 1976-02-12 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija kondensirovannykh proizvodnykh pirimidina
US4122274A (en) * 1977-05-25 1978-10-24 Bristol-Myers Company 3-Tetrazolo-5,6,7,8-substituted-pyrido[1,2-a]pyrimidin-4-ones
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents

Also Published As

Publication number Publication date
DK153150C (da) 1988-10-24
FI62085B (fi) 1982-07-30
SE433353B (sv) 1984-05-21
CH630378A5 (de) 1982-06-15
AU512256B2 (en) 1980-10-02
GB1531963A (en) 1978-11-15
DE2653257A1 (de) 1977-06-02
US4460771A (en) 1984-07-17
ES453690A1 (es) 1977-12-01
NL7613140A (nl) 1977-06-01
BG31227A4 (bg) 1981-11-16
FI62085C (fi) 1982-11-10
YU147583A (en) 1986-06-30
PL109657B1 (en) 1980-06-30
RO73522A (ro) 1981-11-04
JPS5268198A (en) 1977-06-06
RO79705A (ro) 1982-08-17
SE7613140L (sv) 1977-05-28
CA1088531A (en) 1980-10-28
AT359506B (de) 1980-11-10
FI763401A (xx) 1977-05-28
NL188948C (nl) 1992-11-16
GR61820B (en) 1979-01-22
FR2332755B1 (xx) 1978-12-22
CH630379A5 (de) 1982-06-15
DE2653257C2 (xx) 1989-04-20
EG12495A (en) 1980-12-31
MX5178E (es) 1983-04-20
YU289076A (en) 1983-12-31
IL50930A0 (en) 1977-01-31
DD130431A5 (de) 1978-03-29
AU1975976A (en) 1978-05-25
IN148945B (xx) 1981-07-25
DK534076A (da) 1977-05-28
US4472398A (en) 1984-09-18
IL50930A (en) 1981-06-29
DK153150B (da) 1988-06-20
JPS5914033B2 (ja) 1984-04-02
SU698532A3 (ru) 1979-11-15
CS203135B2 (en) 1981-02-27
SU664565A3 (ru) 1979-05-25
NL188948B (nl) 1992-06-16
ATA873576A (de) 1980-04-15
HU173438B (hu) 1979-05-28
FR2332755A1 (fr) 1977-06-24

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.

Effective date: 19941130