SE431655B - Analogiforfaranden for framstellning av nya 9-klorprednisolon-derivat - Google Patents

Analogiforfaranden for framstellning av nya 9-klorprednisolon-derivat

Info

Publication number
SE431655B
SE431655B SE7711039A SE7711039A SE431655B SE 431655 B SE431655 B SE 431655B SE 7711039 A SE7711039 A SE 7711039A SE 7711039 A SE7711039 A SE 7711039A SE 431655 B SE431655 B SE 431655B
Authority
SE
Sweden
Prior art keywords
chloropednisolone
derivatives
preparation
new
analogy
Prior art date
Application number
SE7711039A
Other languages
English (en)
Swedish (sv)
Other versions
SE7711039L (sv
Inventor
K Annen
H Laurent
H Hofmeister
R Wiechert
H Wendt
J F Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/de
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of SE7711039L publication Critical patent/SE7711039L/
Publication of SE431655B publication Critical patent/SE431655B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7711039A 1976-10-04 1977-10-03 Analogiforfaranden for framstellning av nya 9-klorprednisolon-derivat SE431655B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (de) 1976-10-04 1976-10-04 Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat
DE19772742982 DE2742982C2 (de) 1977-09-21 1977-09-21 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat

Publications (2)

Publication Number Publication Date
SE7711039L SE7711039L (sv) 1978-04-05
SE431655B true SE431655B (sv) 1984-02-20

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7711039A SE431655B (sv) 1976-10-04 1977-10-03 Analogiforfaranden for framstellning av nya 9-klorprednisolon-derivat

Country Status (21)

Country Link
JP (1) JPS5359654A (fi)
AT (1) AT358202B (fi)
CH (4) CH630098A5 (fi)
DK (1) DK438277A (fi)
ES (1) ES462887A1 (fi)
FI (1) FI58645C (fi)
FR (1) FR2366313A1 (fi)
GB (1) GB1594852A (fi)
GR (1) GR73041B (fi)
HU (1) HU179593B (fi)
IE (1) IE45877B1 (fi)
IL (1) IL53030A (fi)
IT (1) IT1113623B (fi)
LU (1) LU78223A1 (fi)
NL (1) NL7710869A (fi)
NO (1) NO148597C (fi)
NZ (1) NZ185295A (fi)
PL (1) PL110392B1 (fi)
PT (1) PT67109B (fi)
SE (1) SE431655B (fi)
SU (2) SU743581A3 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH0374245A (ja) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd 洗車機
CN106038476B (zh) 2010-03-26 2020-04-17 盖尔德马研究及发展公司 安全和有效治疗红斑的改进的方法和组合物
WO2013057579A2 (en) 2011-10-19 2013-04-25 Galderma Pharma S.A. Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (zh) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 一种二氟泼尼酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH429716A (de) * 1961-06-24 1967-02-15 Vismara Francesco Spa Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
IE45877B1 (en) 1982-12-15
PL201161A1 (pl) 1979-01-29
IT1113623B (it) 1986-01-20
FI58645B (fi) 1980-11-28
FI58645C (fi) 1981-03-10
SE7711039L (sv) 1978-04-05
CH632278A5 (en) 1982-09-30
GR73041B (fi) 1984-01-26
NO148597B (no) 1983-08-01
DK438277A (da) 1978-04-05
FR2366313A1 (fr) 1978-04-28
JPS5359654A (en) 1978-05-29
ATA703577A (de) 1980-01-15
NO773362L (no) 1978-04-05
AT358202B (de) 1980-08-25
JPS6129960B2 (fi) 1986-07-10
PL110392B1 (en) 1980-07-31
FI772922A (fi) 1978-04-05
LU78223A1 (fi) 1978-02-01
IE45877L (en) 1978-04-04
SU743581A3 (ru) 1980-06-25
CH630098A5 (en) 1982-05-28
NO148597C (no) 1983-11-09
ES462887A1 (es) 1978-12-16
PT67109A (de) 1977-11-01
GB1594852A (en) 1981-08-05
NL7710869A (nl) 1978-04-06
FR2366313B1 (fi) 1980-02-01
IL53030A0 (en) 1977-11-30
IL53030A (en) 1982-11-30
HU179593B (en) 1982-11-29
SU751327A3 (ru) 1980-07-23
CH631997A5 (en) 1982-09-15
PT67109B (de) 1979-03-14
NZ185295A (en) 1980-04-28
CH632772A5 (en) 1982-10-29

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