SE428020B - Forfarande for framstellning av optiskt aktiva isomerer av 3-substituerade cis- och trans-1-hydroxi-6,6-dimetyl-6,6a-7,8,10,10a-hexahydro-9h-dibenso(b,d)-pyran-9-oner - Google Patents

Forfarande for framstellning av optiskt aktiva isomerer av 3-substituerade cis- och trans-1-hydroxi-6,6-dimetyl-6,6a-7,8,10,10a-hexahydro-9h-dibenso(b,d)-pyran-9-oner

Info

Publication number
SE428020B
SE428020B SE7707633A SE7707633A SE428020B SE 428020 B SE428020 B SE 428020B SE 7707633 A SE7707633 A SE 7707633A SE 7707633 A SE7707633 A SE 7707633A SE 428020 B SE428020 B SE 428020B
Authority
SE
Sweden
Prior art keywords
dibenso
pyrane
hexahydro
trans
hydroxy
Prior art date
Application number
SE7707633A
Other languages
English (en)
Swedish (sv)
Other versions
SE7707633L (sv
Inventor
R A Archer
W A Day
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of SE7707633L publication Critical patent/SE7707633L/xx
Publication of SE428020B publication Critical patent/SE428020B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
SE7707633A 1976-11-10 1977-06-30 Forfarande for framstellning av optiskt aktiva isomerer av 3-substituerade cis- och trans-1-hydroxi-6,6-dimetyl-6,6a-7,8,10,10a-hexahydro-9h-dibenso(b,d)-pyran-9-oner SE428020B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/740,502 US4102902A (en) 1976-11-10 1976-11-10 Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor

Publications (2)

Publication Number Publication Date
SE7707633L SE7707633L (sv) 1978-05-11
SE428020B true SE428020B (sv) 1983-05-30

Family

ID=24976773

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7707633A SE428020B (sv) 1976-11-10 1977-06-30 Forfarande for framstellning av optiskt aktiva isomerer av 3-substituerade cis- och trans-1-hydroxi-6,6-dimetyl-6,6a-7,8,10,10a-hexahydro-9h-dibenso(b,d)-pyran-9-oner
SE8005316A SE434510B (sv) 1976-11-10 1980-07-22 Substituerad 4-(2,6-dihydroxifenyl)-6,6-dimetyl-2-norpinanon till anvendning som mellanprodukt
SE8005314A SE8005314L (sv) 1976-11-10 1980-07-22 Forfarande for framstellning av en joptisk aktiv norpinenforening

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE8005316A SE434510B (sv) 1976-11-10 1980-07-22 Substituerad 4-(2,6-dihydroxifenyl)-6,6-dimetyl-2-norpinanon till anvendning som mellanprodukt
SE8005314A SE8005314L (sv) 1976-11-10 1980-07-22 Forfarande for framstellning av en joptisk aktiv norpinenforening

Country Status (30)

Country Link
US (1) US4102902A (bg)
JP (2) JPS5925792B2 (bg)
AT (1) AT356103B (bg)
AU (1) AU509355B2 (bg)
BE (1) BE856413A (bg)
BG (2) BG28061A3 (bg)
CA (1) CA1101875A (bg)
CH (2) CH632506A5 (bg)
CS (1) CS196376B2 (bg)
DD (2) DD140455A5 (bg)
DE (3) DE2760006C2 (bg)
DK (1) DK301477A (bg)
ES (3) ES460388A1 (bg)
FR (1) FR2370742A1 (bg)
GB (2) GB1584182A (bg)
GR (1) GR66417B (bg)
HU (2) HU177308B (bg)
IE (1) IE45247B1 (bg)
IL (3) IL52427A (bg)
MX (1) MX5172E (bg)
NL (1) NL7707467A (bg)
NZ (1) NZ184526A (bg)
PH (3) PH13827A (bg)
PL (2) PL104356B1 (bg)
PT (1) PT66746B (bg)
RO (1) RO78780A (bg)
SE (3) SE428020B (bg)
SU (2) SU786898A3 (bg)
YU (1) YU163677A (bg)
ZA (1) ZA773960B (bg)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL55274A (en) * 1978-08-02 1982-08-31 Yissum Res Dev Co 4-(2,6-dihydroxy-4-(dimethylheptyl)phenyl)substituted 2-pinen-10-ol and pinane derivatives,their preparation and pharmaceutical compositions comprising them
US4939169A (en) * 1985-09-20 1990-07-03 The Upjohn Company 1,4-naphthalenediol and 1,4-hydroquinone derivatives
US4851586A (en) * 1985-09-20 1989-07-25 The Upjohn Company 1,4-naphthalenediol and 1,4-hydroquinone derivatives
IL80411A (en) * 1986-10-24 1991-08-16 Raphael Mechoulam Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them
JPH0315035A (ja) * 1989-03-03 1991-01-23 Konica Corp カメラ
JP2577671B2 (ja) * 1990-06-11 1997-02-05 高砂熱学工業株式会社 気化式精密加湿装置
ATE247097T1 (de) * 1998-05-04 2003-08-15 Univ Connecticut Analgetische und immunomodulierende cannabinoiden
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
MXPA02005104A (es) * 1999-10-18 2003-09-25 Alexipharma Inc Agonistas novedosos de canabinoide biciclico para el receptor canabinoide.
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
CA2387764A1 (en) 1999-10-18 2001-04-26 University Of Connecticut Peripheral cannabinoid receptor (cb2) selective ligands
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
JP2004532185A (ja) * 2001-01-26 2004-10-21 ユニバーシティ オブ コネチカット 新規なカンナビミメティックリガンド
JP2005503998A (ja) 2001-01-29 2005-02-10 ユニバーシティ オブ コネチカット 受容体選択性のカンナビミメティックアミノアルキルインドール
EP1414775B1 (en) * 2001-07-13 2012-12-19 The University of Connecticut Bicyclic cannabinoid
CA2464333C (en) * 2001-10-26 2011-07-26 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
US7285687B2 (en) * 2002-04-25 2007-10-23 Virginia Commonwealth University Cannabinoids
US7183313B2 (en) 2002-08-23 2007-02-27 University Of Connecticut Keto cannabinoids with therapeutic indications
EP1928853A4 (en) 2005-09-29 2011-02-16 Amr Technology Inc PROCESS FOR THE PRODUCTION OF DELTA-9-TETRAHYDROCANNABINOL
US9763894B2 (en) * 2006-12-05 2017-09-19 Virginia Commonwealth University Inflammation therapy
PL222532B1 (pl) 2012-04-05 2016-08-31 Akademia Morska W Szczecinie Sposób i układ do diagnozowania układu wtryskowego silników o zapłonie samoczynnym, zwłaszcza silników okrętowych
US12029718B2 (en) 2021-11-09 2024-07-09 Cct Sciences, Llc Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856820A (en) * 1973-07-18 1974-12-24 Smithkline Corp 2-AMINOMETHYL DIBENZO (b,d) PYRANS
US3856822A (en) * 1973-07-18 1974-12-24 Smithkline Corp 3-alkenyl dibenzo (b,d)pyrans
US3856821A (en) * 1973-07-18 1974-12-24 Smithkline Corp ALKOXY DIBENZO (b,d) PYRANS
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug

Also Published As

Publication number Publication date
JPS5359670A (en) 1978-05-29
CA1101875A (en) 1981-05-26
IL52427A0 (en) 1977-08-31
SE7707633L (sv) 1978-05-11
SE8005316L (sv) 1980-07-22
BE856413A (fr) 1978-01-04
HU177308B (en) 1981-09-28
SE8005314L (sv) 1980-07-22
YU163677A (en) 1982-10-31
BG28411A4 (bg) 1980-04-15
MX5172E (es) 1983-04-18
CS196376B2 (en) 1980-03-31
PH13890A (en) 1980-10-27
PL199362A1 (pl) 1978-05-22
PT66746B (en) 1978-11-27
NZ184526A (en) 1979-03-16
PT66746A (en) 1977-07-01
AU2668477A (en) 1979-01-04
JPS5912654B2 (ja) 1984-03-24
IE45247B1 (en) 1982-07-14
GB1584181A (en) 1981-02-11
BG28061A3 (bg) 1980-02-25
DE2760006C2 (de) 1985-07-04
PL104356B1 (pl) 1979-08-31
DK301477A (da) 1978-05-11
DE2729859C2 (de) 1984-08-23
DE2729859A1 (de) 1978-05-11
FR2370742B1 (bg) 1980-12-26
HU183286B (en) 1984-04-28
SE434510B (sv) 1984-07-30
CH632481A5 (de) 1982-10-15
IL60590A0 (en) 1980-09-16
ATA483677A (de) 1979-09-15
ZA773960B (en) 1979-02-28
DD134350A5 (de) 1979-02-21
JPS5865244A (ja) 1983-04-18
SU786898A3 (ru) 1980-12-07
IE45247L (en) 1978-05-10
AU509355B2 (en) 1980-05-08
IL52427A (en) 1981-10-30
ES460388A1 (es) 1978-04-01
CH632506A5 (de) 1982-10-15
DD140455A5 (de) 1980-03-05
FR2370742A1 (fr) 1978-06-09
US4102902A (en) 1978-07-25
GB1584182A (en) 1981-02-11
RO78780A (ro) 1982-04-12
GR66417B (bg) 1981-03-20
PH14708A (en) 1981-11-13
DE2760005C2 (de) 1984-04-26
SU1128829A3 (ru) 1984-12-07
NL7707467A (nl) 1978-05-12
JPS5925792B2 (ja) 1984-06-21
IL60589A0 (en) 1980-09-16
AT356103B (de) 1980-04-10
PH13827A (en) 1980-10-07
ES460387A1 (es) 1978-04-01
PL104432B1 (pl) 1979-08-31
ES460389A1 (es) 1978-04-16

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