SE416546B - Forfarande for framstellning av en 3-amino-2-hydroxi-1-fenoxi-propanforening med en acylgrupp substituerad vid fenoxigruppen - Google Patents
Forfarande for framstellning av en 3-amino-2-hydroxi-1-fenoxi-propanforening med en acylgrupp substituerad vid fenoxigruppenInfo
- Publication number
- SE416546B SE416546B SE7507359A SE7507359A SE416546B SE 416546 B SE416546 B SE 416546B SE 7507359 A SE7507359 A SE 7507359A SE 7507359 A SE7507359 A SE 7507359A SE 416546 B SE416546 B SE 416546B
- Authority
- SE
- Sweden
- Prior art keywords
- phenoxy
- hydroxy
- amino
- preparing
- procedure
- Prior art date
Links
- -1 3-AMINO-2-HYDROXY-1-PHENOXY PROPANE COMPOUND Chemical class 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB28925/74A GB1501632A (en) | 1974-06-28 | 1974-06-28 | Aromatic ketones having cardiovascular activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7507359L SE7507359L (sv) | 1975-12-29 |
| SE416546B true SE416546B (sv) | 1981-01-19 |
Family
ID=10283421
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7507359A SE416546B (sv) | 1974-06-28 | 1975-06-26 | Forfarande for framstellning av en 3-amino-2-hydroxi-1-fenoxi-propanforening med en acylgrupp substituerad vid fenoxigruppen |
| SE7812646A SE417087B (sv) | 1974-06-28 | 1978-12-08 | Forfarande for framstellning av en 3-(2-acyl-fenoxi)-1-alkylamino-propan-2-ol |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7812646A SE417087B (sv) | 1974-06-28 | 1978-12-08 | Forfarande for framstellning av en 3-(2-acyl-fenoxi)-1-alkylamino-propan-2-ol |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US4252825A (Direct) |
| JP (2) | JPS5826743B2 (Direct) |
| AR (1) | AR205388A1 (Direct) |
| AT (1) | AT343098B (Direct) |
| BE (1) | BE830766A (Direct) |
| CA (1) | CA1052820A (Direct) |
| CS (1) | CS197248B2 (Direct) |
| DE (1) | DE2528147A1 (Direct) |
| DK (1) | DK143555C (Direct) |
| ES (1) | ES438931A1 (Direct) |
| FR (1) | FR2276032A1 (Direct) |
| GB (1) | GB1501632A (Direct) |
| IE (1) | IE41386B1 (Direct) |
| NL (1) | NL7507703A (Direct) |
| SE (2) | SE416546B (Direct) |
| YU (1) | YU165775A (Direct) |
| ZA (1) | ZA754141B (Direct) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1501632A (en) * | 1974-06-28 | 1978-02-22 | Cm Ind | Aromatic ketones having cardiovascular activity |
| JPH0516363Y2 (Direct) * | 1986-08-01 | 1993-04-28 | ||
| EP1545519B1 (en) | 2002-08-19 | 2011-03-23 | Pfizer Inc. | Combination therapy for hyperproliferative diseases |
| KR20110117731A (ko) * | 2003-05-30 | 2011-10-27 | 랜박시 래보러터리스 리미티드 | 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도 |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| AU2006313430B2 (en) * | 2005-11-08 | 2012-09-06 | Ranbaxy Laboratories Limited | Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| CL2007000667A1 (es) * | 2006-03-14 | 2008-03-14 | Ranbaxi Lab Ltd | Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e |
| TW200811101A (en) * | 2006-07-14 | 2008-03-01 | Ranbaxy Lab Ltd | Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof |
| EP2094643B1 (en) | 2006-12-01 | 2012-02-29 | Bristol-Myers Squibb Company | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases |
| KR101695582B1 (ko) | 2013-04-17 | 2017-01-13 | 화이자 인코포레이티드 | 심혈관 질환을 치료하기 위한 n-피페리딘-3-일벤즈아미드 유도체 |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| CN119060040A (zh) | 2019-01-18 | 2024-12-03 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL301580A (Direct) * | 1962-12-11 | |||
| DE1493454C3 (de) * | 1963-08-26 | 1980-04-30 | C.H. Boehringer Sohn, 6507 Ingelheim | 1 -Aryloxy^-hydroxy-S-isopropylaminopropane und deren Salze sowie deren Herstellung und darauf basierende Arzneimittel |
| US3637852A (en) * | 1963-08-26 | 1972-01-25 | Boehringer Sohn Ingelheim | 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof |
| GB1231783A (en) * | 1967-05-16 | 1971-05-12 | May & Baker Ltd | Benzene derivatives |
| JPS512115B2 (Direct) * | 1971-09-28 | 1976-01-23 | ||
| JPS4911847A (Direct) * | 1972-05-20 | 1974-02-01 | ||
| GB1501632A (en) * | 1974-06-28 | 1978-02-22 | Cm Ind | Aromatic ketones having cardiovascular activity |
-
1974
- 1974-06-28 GB GB28925/74A patent/GB1501632A/en not_active Expired
-
1975
- 1975-01-01 AR AR259407A patent/AR205388A1/es active
- 1975-06-20 FR FR7519386A patent/FR2276032A1/fr active Granted
- 1975-06-24 IE IE1395/75A patent/IE41386B1/xx unknown
- 1975-06-24 CS CS754483A patent/CS197248B2/cs unknown
- 1975-06-24 DE DE19752528147 patent/DE2528147A1/de not_active Withdrawn
- 1975-06-26 SE SE7507359A patent/SE416546B/xx unknown
- 1975-06-27 NL NL7507703A patent/NL7507703A/xx not_active Application Discontinuation
- 1975-06-27 ZA ZA00754141A patent/ZA754141B/xx unknown
- 1975-06-27 AT AT497275A patent/AT343098B/de not_active IP Right Cessation
- 1975-06-27 BE BE157788A patent/BE830766A/xx not_active IP Right Cessation
- 1975-06-27 YU YU01657/75A patent/YU165775A/xx unknown
- 1975-06-27 CA CA230,291A patent/CA1052820A/en not_active Expired
- 1975-06-27 DK DK292475A patent/DK143555C/da not_active IP Right Cessation
- 1975-06-27 ES ES438931A patent/ES438931A1/es not_active Expired
- 1975-06-28 JP JP50080469A patent/JPS5826743B2/ja not_active Expired
-
1978
- 1978-12-08 SE SE7812646A patent/SE417087B/sv unknown
-
1979
- 1979-01-05 US US06/001,314 patent/US4252825A/en not_active Expired - Lifetime
-
1980
- 1980-03-12 US US06/129,730 patent/US4302601A/en not_active Expired - Lifetime
-
1983
- 1983-01-07 JP JP58001033A patent/JPS5929574B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2528147A1 (de) | 1976-01-15 |
| CS197248B2 (en) | 1980-04-30 |
| FR2276032B1 (Direct) | 1979-08-10 |
| CA1052820A (en) | 1979-04-17 |
| JPS5826743B2 (ja) | 1983-06-04 |
| ATA497275A (de) | 1977-09-15 |
| ZA754141B (en) | 1976-06-30 |
| BE830766A (fr) | 1975-12-29 |
| JPS5123233A (en) | 1976-02-24 |
| SE7507359L (sv) | 1975-12-29 |
| AU8256675A (en) | 1977-01-06 |
| JPS5929574B2 (ja) | 1984-07-21 |
| SE417087B (sv) | 1981-02-23 |
| JPS58140050A (ja) | 1983-08-19 |
| SE7812646L (sv) | 1978-12-08 |
| ES438931A1 (es) | 1977-05-16 |
| US4252825A (en) | 1981-02-24 |
| FR2276032A1 (fr) | 1976-01-23 |
| NL7507703A (nl) | 1975-12-30 |
| DK143555B (da) | 1981-09-07 |
| IE41386B1 (en) | 1979-12-19 |
| US4302601A (en) | 1981-11-24 |
| DK292475A (da) | 1975-12-29 |
| GB1501632A (en) | 1978-02-22 |
| IE41386L (en) | 1975-12-28 |
| DK143555C (da) | 1982-02-01 |
| AT343098B (de) | 1978-05-10 |
| AR205388A1 (es) | 1976-04-30 |
| YU165775A (en) | 1982-02-28 |
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