DK143555C - Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf - Google Patents
Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere herafInfo
- Publication number
- DK143555C DK143555C DK292475A DK292475A DK143555C DK 143555 C DK143555 C DK 143555C DK 292475 A DK292475 A DK 292475A DK 292475 A DK292475 A DK 292475A DK 143555 C DK143555 C DK 143555C
- Authority
- DK
- Denmark
- Prior art keywords
- butylaminopropoxy
- butyrophenone
- analogue
- fluoro
- tert
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB28925/74A GB1501632A (en) | 1974-06-28 | 1974-06-28 | Aromatic ketones having cardiovascular activity |
| GB2892574 | 1974-06-28 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK292475A DK292475A (da) | 1975-12-29 |
| DK143555B DK143555B (da) | 1981-09-07 |
| DK143555C true DK143555C (da) | 1982-02-01 |
Family
ID=10283421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK292475A DK143555C (da) | 1974-06-28 | 1975-06-27 | Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US4252825A (da) |
| JP (2) | JPS5826743B2 (da) |
| AR (1) | AR205388A1 (da) |
| AT (1) | AT343098B (da) |
| BE (1) | BE830766A (da) |
| CA (1) | CA1052820A (da) |
| CS (1) | CS197248B2 (da) |
| DE (1) | DE2528147A1 (da) |
| DK (1) | DK143555C (da) |
| ES (1) | ES438931A1 (da) |
| FR (1) | FR2276032A1 (da) |
| GB (1) | GB1501632A (da) |
| IE (1) | IE41386B1 (da) |
| NL (1) | NL7507703A (da) |
| SE (2) | SE416546B (da) |
| YU (1) | YU165775A (da) |
| ZA (1) | ZA754141B (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1501632A (en) * | 1974-06-28 | 1978-02-22 | Cm Ind | Aromatic ketones having cardiovascular activity |
| JPH0516363Y2 (da) * | 1986-08-01 | 1993-04-28 | ||
| CN1681495B (zh) | 2002-08-19 | 2010-05-12 | 辉瑞产品公司 | 用于治疗过度增生性疾病的组合物 |
| KR20110117731A (ko) * | 2003-05-30 | 2011-10-27 | 랜박시 래보러터리스 리미티드 | 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의 용도 |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| AU2006313430B2 (en) * | 2005-11-08 | 2012-09-06 | Ranbaxy Laboratories Limited | Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| WO2008020314A2 (en) * | 2006-03-14 | 2008-02-21 | Ranbaxy Laboratories Limited | Statin stabilizing dosage formulations |
| WO2008010087A2 (en) * | 2006-07-14 | 2008-01-24 | Ranbaxy Laboratories Limited | Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof |
| JP5498168B2 (ja) | 2006-12-01 | 2014-05-21 | ブリストル−マイヤーズ スクイブ カンパニー | アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体 |
| EP2986599A1 (en) | 2013-04-17 | 2016-02-24 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| BR112021013807A2 (pt) | 2019-01-18 | 2021-11-30 | Astrazeneca Ab | Inibidores de pcsk9 e seus métodos de uso |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL301580A (da) * | 1962-12-11 | |||
| DE1493454C3 (de) * | 1963-08-26 | 1980-04-30 | C.H. Boehringer Sohn, 6507 Ingelheim | 1 -Aryloxy^-hydroxy-S-isopropylaminopropane und deren Salze sowie deren Herstellung und darauf basierende Arzneimittel |
| US3637852A (en) * | 1963-08-26 | 1972-01-25 | Boehringer Sohn Ingelheim | 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof |
| GB1231783A (en) * | 1967-05-16 | 1971-05-12 | May & Baker Ltd | Benzene derivatives |
| JPS512115B2 (da) * | 1971-09-28 | 1976-01-23 | ||
| JPS4911847A (da) * | 1972-05-20 | 1974-02-01 | ||
| GB1501632A (en) * | 1974-06-28 | 1978-02-22 | Cm Ind | Aromatic ketones having cardiovascular activity |
-
1974
- 1974-06-28 GB GB28925/74A patent/GB1501632A/en not_active Expired
-
1975
- 1975-01-01 AR AR259407A patent/AR205388A1/es active
- 1975-06-20 FR FR7519386A patent/FR2276032A1/fr active Granted
- 1975-06-24 CS CS754483A patent/CS197248B2/cs unknown
- 1975-06-24 DE DE19752528147 patent/DE2528147A1/de not_active Withdrawn
- 1975-06-24 IE IE1395/75A patent/IE41386B1/xx unknown
- 1975-06-26 SE SE7507359A patent/SE416546B/xx unknown
- 1975-06-27 CA CA230,291A patent/CA1052820A/en not_active Expired
- 1975-06-27 ZA ZA00754141A patent/ZA754141B/xx unknown
- 1975-06-27 ES ES438931A patent/ES438931A1/es not_active Expired
- 1975-06-27 NL NL7507703A patent/NL7507703A/xx not_active Application Discontinuation
- 1975-06-27 YU YU01657/75A patent/YU165775A/xx unknown
- 1975-06-27 DK DK292475A patent/DK143555C/da not_active IP Right Cessation
- 1975-06-27 BE BE157788A patent/BE830766A/xx not_active IP Right Cessation
- 1975-06-27 AT AT497275A patent/AT343098B/de not_active IP Right Cessation
- 1975-06-28 JP JP50080469A patent/JPS5826743B2/ja not_active Expired
-
1978
- 1978-12-08 SE SE7812646A patent/SE417087B/sv unknown
-
1979
- 1979-01-05 US US06/001,314 patent/US4252825A/en not_active Expired - Lifetime
-
1980
- 1980-03-12 US US06/129,730 patent/US4302601A/en not_active Expired - Lifetime
-
1983
- 1983-01-07 JP JP58001033A patent/JPS5929574B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5826743B2 (ja) | 1983-06-04 |
| IE41386L (en) | 1975-12-28 |
| SE416546B (sv) | 1981-01-19 |
| DK292475A (da) | 1975-12-29 |
| GB1501632A (en) | 1978-02-22 |
| ZA754141B (en) | 1976-06-30 |
| JPS5929574B2 (ja) | 1984-07-21 |
| SE7812646L (sv) | 1978-12-08 |
| US4302601A (en) | 1981-11-24 |
| FR2276032B1 (da) | 1979-08-10 |
| BE830766A (fr) | 1975-12-29 |
| FR2276032A1 (fr) | 1976-01-23 |
| ATA497275A (de) | 1977-09-15 |
| NL7507703A (nl) | 1975-12-30 |
| JPS58140050A (ja) | 1983-08-19 |
| AR205388A1 (es) | 1976-04-30 |
| IE41386B1 (en) | 1979-12-19 |
| CS197248B2 (en) | 1980-04-30 |
| DK143555B (da) | 1981-09-07 |
| SE417087B (sv) | 1981-02-23 |
| AU8256675A (en) | 1977-01-06 |
| AT343098B (de) | 1978-05-10 |
| ES438931A1 (es) | 1977-05-16 |
| YU165775A (en) | 1982-02-28 |
| JPS5123233A (en) | 1976-02-24 |
| US4252825A (en) | 1981-02-24 |
| DE2528147A1 (de) | 1976-01-15 |
| SE7507359L (sv) | 1975-12-29 |
| CA1052820A (en) | 1979-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |