ATA497275A - Verfahren zur herstellung von neuen 3-(2'-acylphenoxy)-2-hydroxy-1-alkylaminopropanen und deren saureadditionssalzen - Google Patents

Verfahren zur herstellung von neuen 3-(2'-acylphenoxy)-2-hydroxy-1-alkylaminopropanen und deren saureadditionssalzen

Info

Publication number
ATA497275A
ATA497275A AT497275A AT497275A ATA497275A AT A497275 A ATA497275 A AT A497275A AT 497275 A AT497275 A AT 497275A AT 497275 A AT497275 A AT 497275A AT A497275 A ATA497275 A AT A497275A
Authority
AT
Austria
Prior art keywords
alkylaminopropanes
acylphenoxy
hydroxy
preparation
new
Prior art date
Application number
AT497275A
Other languages
English (en)
Other versions
AT343098B (de
Inventor
Henri Demarne
Original Assignee
Clin Midy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clin Midy filed Critical Clin Midy
Priority to AT23077A priority Critical patent/AT345270B/de
Publication of ATA497275A publication Critical patent/ATA497275A/de
Application granted granted Critical
Publication of AT343098B publication Critical patent/AT343098B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT497275A 1974-06-28 1975-06-27 Verfahren zur herstellung von neuen 3-(2'-acylphenoxy)-2-hydroxy-1-alkylaminopropanen und deren saureadditionssalzen AT343098B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT23077A AT345270B (de) 1974-06-28 1977-01-17 Verfahren zur herstellung neuer derivate des amino-3-hydroxy-2-phenoxy-1-propans

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB28925/74A GB1501632A (en) 1974-06-28 1974-06-28 Aromatic ketones having cardiovascular activity

Publications (2)

Publication Number Publication Date
ATA497275A true ATA497275A (de) 1977-09-15
AT343098B AT343098B (de) 1978-05-10

Family

ID=10283421

Family Applications (1)

Application Number Title Priority Date Filing Date
AT497275A AT343098B (de) 1974-06-28 1975-06-27 Verfahren zur herstellung von neuen 3-(2'-acylphenoxy)-2-hydroxy-1-alkylaminopropanen und deren saureadditionssalzen

Country Status (17)

Country Link
US (2) US4252825A (de)
JP (2) JPS5826743B2 (de)
AR (1) AR205388A1 (de)
AT (1) AT343098B (de)
BE (1) BE830766A (de)
CA (1) CA1052820A (de)
CS (1) CS197248B2 (de)
DE (1) DE2528147A1 (de)
DK (1) DK143555C (de)
ES (1) ES438931A1 (de)
FR (1) FR2276032A1 (de)
GB (1) GB1501632A (de)
IE (1) IE41386B1 (de)
NL (1) NL7507703A (de)
SE (2) SE416546B (de)
YU (1) YU165775A (de)
ZA (1) ZA754141B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1501632A (en) * 1974-06-28 1978-02-22 Cm Ind Aromatic ketones having cardiovascular activity
JPH0516363Y2 (de) * 1986-08-01 1993-04-28
CN1681495B (zh) 2002-08-19 2010-05-12 辉瑞产品公司 用于治疗过度增生性疾病的组合物
KR20110117731A (ko) * 2003-05-30 2011-10-27 랜박시 래보러터리스 리미티드 치환된 피롤 유도체와 hmg―co 억제제로서의 이의 용도
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
AU2006313430B2 (en) * 2005-11-08 2012-09-06 Ranbaxy Laboratories Limited Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008020314A2 (en) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Statin stabilizing dosage formulations
WO2008010087A2 (en) * 2006-07-14 2008-01-24 Ranbaxy Laboratories Limited Polymorphic forms of an hmg-coa reductase inhibitor and uses thereof
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのcetp阻害剤としてのn−((3−ベンジル)−2,2−(ビス−フェニル)−プロパン−1−アミン誘導体
EP2986599A1 (de) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamid-derivate zur behandlung von herz-kreislauf-erkrankungen
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
BR112021013807A2 (pt) 2019-01-18 2021-11-30 Astrazeneca Ab Inibidores de pcsk9 e seus métodos de uso

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL301580A (de) * 1962-12-11
DE1493454C3 (de) * 1963-08-26 1980-04-30 C.H. Boehringer Sohn, 6507 Ingelheim 1 -Aryloxy^-hydroxy-S-isopropylaminopropane und deren Salze sowie deren Herstellung und darauf basierende Arzneimittel
US3637852A (en) * 1963-08-26 1972-01-25 Boehringer Sohn Ingelheim 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof
GB1231783A (en) * 1967-05-16 1971-05-12 May & Baker Ltd Benzene derivatives
JPS512115B2 (de) * 1971-09-28 1976-01-23
JPS4911847A (de) * 1972-05-20 1974-02-01
GB1501632A (en) * 1974-06-28 1978-02-22 Cm Ind Aromatic ketones having cardiovascular activity

Also Published As

Publication number Publication date
JPS5826743B2 (ja) 1983-06-04
DK143555C (da) 1982-02-01
IE41386L (en) 1975-12-28
SE416546B (sv) 1981-01-19
DK292475A (da) 1975-12-29
GB1501632A (en) 1978-02-22
ZA754141B (en) 1976-06-30
JPS5929574B2 (ja) 1984-07-21
SE7812646L (sv) 1978-12-08
US4302601A (en) 1981-11-24
FR2276032B1 (de) 1979-08-10
BE830766A (fr) 1975-12-29
FR2276032A1 (fr) 1976-01-23
NL7507703A (nl) 1975-12-30
JPS58140050A (ja) 1983-08-19
AR205388A1 (es) 1976-04-30
IE41386B1 (en) 1979-12-19
CS197248B2 (en) 1980-04-30
DK143555B (da) 1981-09-07
SE417087B (sv) 1981-02-23
AU8256675A (en) 1977-01-06
AT343098B (de) 1978-05-10
ES438931A1 (es) 1977-05-16
YU165775A (en) 1982-02-28
JPS5123233A (en) 1976-02-24
US4252825A (en) 1981-02-24
DE2528147A1 (de) 1976-01-15
SE7507359L (sv) 1975-12-29
CA1052820A (en) 1979-04-17

Similar Documents

Publication Publication Date Title
ATA812076A (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saureadditionssalzen
ATA195476A (de) Verfahren zur herstellung von neuen p-trifluormethyl-acylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen
ATA497275A (de) Verfahren zur herstellung von neuen 3-(2'-acylphenoxy)-2-hydroxy-1-alkylaminopropanen und deren saureadditionssalzen
ATA600375A (de) Verfahren zur herstellung von neuen 7-methoxy-6-thiatetracyclinen und deren salzen
ATA592975A (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saureadditionssalzen
ATA414375A (de) Verfahren zur herstellung von neuen 3-(4-acylaminopiperazin-1-yl-alkyl)-indolen sowie deren saeureadditionssalzen
ATA195576A (de) Verfahren zur herstellung von neuen p-halogen-acylophenon- o - (2-aminoathyl)-oximathern und deren saureadditionssalzen
ATA194876A (de) Verfahren zur herstellung von neuen p-methylthioacylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT335997B (de) Verfahren zur herstellung von neuen n'-(aminoacylaminophenyl)-acetamidinen und deren saureadditionssalzen
AT340051B (de) Verfahren zur herstellung von neuen 2-deoxystreptaminaminoglykosiden und deren saureadditionssalzen
AT352735B (de) Verfahren zur herstellung von neuen 2,4- diamino-5-benzylpyrimidinen und deren saeure- additionssalzen
AT324354B (de) Verfahren zur herstellung von neuen n-phenyl-n'-dialkylphosphinylalkylpiperazinen und von deren säureadditionssalzen
ATA195276A (de) Verfahren zur herstellung von neuen p-nitro-acylophenon-o- (2-aminoathyl) -oximather und deren saureadditionssalzen
ATA195176A (de) Verfahren zur herstellung von neuen p-methylsulfinyl-acylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT339281B (de) Verfahren zur herstellung von neuen 1-aryloxy-2-hydroxy-4-sek.aminobutanen und deren nichttoxischen saureadditionssalzen
AT341525B (de) Verfahren zur herstellung von neuen imidazolido- (1,5-c)-thiazolidin-3-spiro-4'-piperadinen und deren saureadditionssalzen
ATA604574A (de) Verfahren zur herstellung von neuen 3-(2',3'-dimethoxyphenoxy)-2-hydroxyaminopropanen und deren saureadditionssalzen
AT335466B (de) Verfahren zur herstellung von neuen 3-(p-ureidophenoxy)-2-hydroxy-aminopropanen und deren saureadditionssalzen
ATA488876A (de) Verfahren zur herstellung von neuen 3-hydroxycrontonsaeureazetidinderivaten und deren salzen
ATA720575A (de) Verfahren zur herstellung von neuen 2,6-methano-3-benzazocinen und deren saureadditionssalzen
ATA816877A (de) Verfahren zur herstellung von neuen 2,6-methano-3-benzazocinen und deren saureadditionssalzen
AT335465B (de) Verfahren zur herstellung von neuen 3-(p-ureidophenoxy)-2-hydroxy-aminopropanen sowie deren saureadditionssalzen
AT335464B (de) Verfahren zur herstellung von neuen 3-(p-ureidophenoxy)-2-hydroxy-aminopropanen sowie deren saureadditionssalzen
ATA328877A (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saureadditionssalzen
ATA805575A (de) Verfahren zur herstellung von neuen substituierten 1-aryloxy-4-amino-2-butanolen und deren saureadditionssalzen

Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee