DK143555C - Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf - Google Patents

Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf

Info

Publication number
DK143555C
DK143555C DK292475A DK292475A DK143555C DK 143555 C DK143555 C DK 143555C DK 292475 A DK292475 A DK 292475A DK 292475 A DK292475 A DK 292475A DK 143555 C DK143555 C DK 143555C
Authority
DK
Denmark
Prior art keywords
butylaminopropoxy
butyrophenone
analogue
fluoro
tert
Prior art date
Application number
DK292475A
Other languages
Danish (da)
English (en)
Other versions
DK292475A (da
DK143555B (da
Inventor
H Demarne
Original Assignee
Clin Midy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clin Midy filed Critical Clin Midy
Publication of DK292475A publication Critical patent/DK292475A/da
Publication of DK143555B publication Critical patent/DK143555B/da
Application granted granted Critical
Publication of DK143555C publication Critical patent/DK143555C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK292475A 1974-06-28 1975-06-27 Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf DK143555C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2892574 1974-06-28
GB28925/74A GB1501632A (en) 1974-06-28 1974-06-28 Aromatic ketones having cardiovascular activity

Publications (3)

Publication Number Publication Date
DK292475A DK292475A (da) 1975-12-29
DK143555B DK143555B (da) 1981-09-07
DK143555C true DK143555C (da) 1982-02-01

Family

ID=10283421

Family Applications (1)

Application Number Title Priority Date Filing Date
DK292475A DK143555C (da) 1974-06-28 1975-06-27 Analogifremgangsmaade til fremstilling af 5-fluor-2-(2-hydroxy-3-tert.-butylaminopropoxy)-butyrophenon eller syreadditionssalte eller optisk aktive isomere heraf

Country Status (17)

Country Link
US (2) US4252825A (de)
JP (2) JPS5826743B2 (de)
AR (1) AR205388A1 (de)
AT (1) AT343098B (de)
BE (1) BE830766A (de)
CA (1) CA1052820A (de)
CS (1) CS197248B2 (de)
DE (1) DE2528147A1 (de)
DK (1) DK143555C (de)
ES (1) ES438931A1 (de)
FR (1) FR2276032A1 (de)
GB (1) GB1501632A (de)
IE (1) IE41386B1 (de)
NL (1) NL7507703A (de)
SE (2) SE416546B (de)
YU (1) YU165775A (de)
ZA (1) ZA754141B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1501632A (en) * 1974-06-28 1978-02-22 Cm Ind Aromatic ketones having cardiovascular activity
JPH0516363Y2 (de) * 1986-08-01 1993-04-28
AU2003250483A1 (en) 2002-08-19 2004-03-11 Pfizer Products Inc. Combination therapy for hyperproliferative diseases
CA2753318A1 (en) * 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Substituted pyrrole derivatives
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US8026377B2 (en) * 2005-11-08 2011-09-27 Ranbaxy Laboratories, Limited Process for (3R, 5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008020314A2 (en) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Statin stabilizing dosage formulations
TW200811101A (en) * 2006-07-14 2008-03-01 Ranbaxy Lab Ltd Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのcetp阻害剤としてのn−((3−ベンジル)−2,2−(ビス−フェニル)−プロパン−1−アミン誘導体
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL301580A (de) * 1962-12-11
DE1493454C3 (de) * 1963-08-26 1980-04-30 C.H. Boehringer Sohn, 6507 Ingelheim 1 -Aryloxy^-hydroxy-S-isopropylaminopropane und deren Salze sowie deren Herstellung und darauf basierende Arzneimittel
US3637852A (en) * 1963-08-26 1972-01-25 Boehringer Sohn Ingelheim 1-phenoxy-2-hydroxy-3-isopropylamino-propanes and salts thereof
GB1231783A (en) * 1967-05-16 1971-05-12 May & Baker Ltd Benzene derivatives
JPS512115B2 (de) * 1971-09-28 1976-01-23
JPS4911847A (de) * 1972-05-20 1974-02-01
GB1501632A (en) * 1974-06-28 1978-02-22 Cm Ind Aromatic ketones having cardiovascular activity

Also Published As

Publication number Publication date
GB1501632A (en) 1978-02-22
JPS5123233A (en) 1976-02-24
ZA754141B (en) 1976-06-30
CS197248B2 (en) 1980-04-30
JPS58140050A (ja) 1983-08-19
DK292475A (da) 1975-12-29
ATA497275A (de) 1977-09-15
US4252825A (en) 1981-02-24
AU8256675A (en) 1977-01-06
YU165775A (en) 1982-02-28
SE7507359L (sv) 1975-12-29
CA1052820A (en) 1979-04-17
ES438931A1 (es) 1977-05-16
IE41386L (en) 1975-12-28
NL7507703A (nl) 1975-12-30
SE7812646L (sv) 1978-12-08
US4302601A (en) 1981-11-24
AT343098B (de) 1978-05-10
DE2528147A1 (de) 1976-01-15
FR2276032A1 (fr) 1976-01-23
JPS5929574B2 (ja) 1984-07-21
JPS5826743B2 (ja) 1983-06-04
AR205388A1 (es) 1976-04-30
DK143555B (da) 1981-09-07
BE830766A (fr) 1975-12-29
SE417087B (sv) 1981-02-23
FR2276032B1 (de) 1979-08-10
IE41386B1 (en) 1979-12-19
SE416546B (sv) 1981-01-19

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