SE391928B - Ny optiskt aktiv tiolaktion till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av tiolaktonen - Google Patents

Ny optiskt aktiv tiolaktion till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av tiolaktonen

Info

Publication number
SE391928B
SE391928B SE7016133A SE1613370A SE391928B SE 391928 B SE391928 B SE 391928B SE 7016133 A SE7016133 A SE 7016133A SE 1613370 A SE1613370 A SE 1613370A SE 391928 B SE391928 B SE 391928B
Authority
SE
Sweden
Prior art keywords
tiolacton
jemte
tiol
biotin
synthesis
Prior art date
Application number
SE7016133A
Other languages
English (en)
Swedish (sv)
Inventor
M Gerecke
J P Zimmermann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE391928B publication Critical patent/SE391928B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE7016133A 1969-11-29 1970-11-27 Ny optiskt aktiv tiolaktion till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av tiolaktonen SE391928B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1777369A CH556867A (de) 1969-11-29 1969-11-29 Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons.

Publications (1)

Publication Number Publication Date
SE391928B true SE391928B (sv) 1977-03-07

Family

ID=4428001

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7016133A SE391928B (sv) 1969-11-29 1970-11-27 Ny optiskt aktiv tiolaktion till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av tiolaktonen

Country Status (10)

Country Link
US (1) US3740416A (xx)
JP (1) JPS5327279B1 (xx)
BE (1) BE759513A (xx)
CA (1) CA982591A (xx)
CH (1) CH556867A (xx)
DK (1) DK154563C (xx)
FR (1) FR2077540B1 (xx)
GB (2) GB1320799A (xx)
NL (1) NL156140B (xx)
SE (1) SE391928B (xx)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054740A (en) * 1974-12-24 1977-10-18 Hoffmann-La Roche Inc. Hydroxybiotin
US4228295A (en) * 1977-02-23 1980-10-14 Hoffmann-La Roche Inc. Novel cycloheptathiophene intermediates for the synthesis of biotin
US4130713A (en) * 1977-08-05 1978-12-19 Hoffmann-La Roche Inc. Biotin intermediates
US4189586A (en) * 1977-08-05 1980-02-19 Hoffmann-La Roche Inc. Preparation of biotin
US4337345A (en) * 1977-08-05 1982-06-29 Hoffmann-La Roche Inc. Preparation of biotin via thieno [3,2c] isoxazoles
US4245104A (en) * 1978-12-01 1981-01-13 Hoffmann-La Roche Inc. Isoxazolines and isoxazolidines
US4284557A (en) * 1979-05-29 1981-08-18 Hoffmann-La Roche Inc. Intermediate racemates for the preparation of biotin and a process for their preparation
US4247704A (en) * 1979-05-29 1981-01-27 Hoffmann-La Roche Inc. Hexahydro thieno imadazole intermediates for the synthesis of biotin
US4537973A (en) * 1980-03-12 1985-08-27 Sumitomo Chemical Company, Limited Process for preparing biotin
DE3068160D1 (en) * 1980-03-14 1984-07-19 Sumitomo Chemical Co Process for preparing biotin
US4320056A (en) * 1980-05-15 1982-03-16 Hoffmann-La Roche Inc. Certain thia-diazatricyclo[3,3,3,08,11 ]tridecanes, and their preparation
US4382031A (en) * 1981-03-12 1983-05-03 Hoffmann-La Roche Inc. Intermediates for the preparation of biotin
DK43985A (da) * 1984-03-09 1985-09-10 Hoffmann La Roche Fremgangsmaade til fremstilling af heterocycliske forbindelser
DE4107121C1 (xx) * 1991-03-06 1992-06-11 Merck Patent Gmbh, 6100 Darmstadt, De
CA2193774C (en) * 1995-12-26 2005-02-01 Norihiko Hirata Process for producing 1-hydroxythienoimidazole carboxylic acid and thienoimidazole carboxylic acid
DE10001317A1 (de) * 2000-01-14 2001-07-19 Merck Patent Gmbh Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien
TW200300676A (en) 2001-12-04 2003-06-16 Tanabe Seiyaku Co Biotin intermediate and its production
CN101096372B (zh) * 2007-01-24 2010-09-29 绍兴文理学院 硫内酯的合成工艺
CN102268007B (zh) * 2010-02-09 2015-11-25 浙江新和成股份有限公司 双苄生物素衍生物的制备方法
CN103788112B (zh) * 2012-11-02 2016-03-09 菏泽市方明制药有限公司 一种苄基生物素脱苄制备生物素的方法
CN103554129B (zh) * 2013-10-09 2016-03-23 安徽泰格维生素实业有限公司 一种生物素中间体硫酮的制备方法
CN107973806A (zh) * 2016-10-21 2018-05-01 大丰海嘉诺药业有限公司 一种制备d-生物素溴盐中间体的方法
JPWO2020110831A1 (ja) * 2018-11-28 2021-10-21 株式会社トクヤマ チオラクトン誘導体の製造方法
WO2021224295A1 (en) 2020-05-07 2021-11-11 Dsm Ip Assets B.V. A process for producing d-biotin intermediates
WO2022260168A1 (ja) * 2021-06-11 2022-12-15 株式会社トクヤマ ヒドロキシチエノイミダゾール誘導体、ビニルスルフィド誘導体、ｎ－ブチリデンスルフィド誘導体、及び飽和直鎖炭化水素置換チエノイミダゾール誘導体の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK71723C (da) * 1946-05-31 1950-11-20 Hoffmann La Roche Fremgangsmåde til fremstilling af d,1-biotin.
DK73837C (da) * 1947-07-24 1952-03-03 Hoffmann La Roche Fremgangsmåde til fremstilling af biotin eller homologe biotinforbindelser.
DK81470C (da) * 1947-07-24 1956-07-30 Hoffmann La Roche Fremgangsmåde til fremstilling af d- og l-biotin.

Also Published As

Publication number Publication date
FR2077540B1 (xx) 1975-12-12
US3740416A (en) 1973-06-19
CH556867A (de) 1974-12-13
NL156140B (nl) 1978-03-15
BE759513A (fr) 1971-05-27
DE2058234A1 (de) 1971-06-09
NL7015567A (xx) 1971-06-02
CA982591A (en) 1976-01-27
FR2077540A1 (xx) 1971-10-29
GB1320799A (en) 1973-06-20
DE2058234B2 (de) 1977-02-17
DK154563C (da) 1989-04-17
GB1320798A (en) 1973-06-20
DK154563B (da) 1988-11-28
JPS5327279B1 (xx) 1978-08-07

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