DK154563C - Fremgangsmaade til fremstilling af en racemisk eller optisk aktiv (+)-thiolacton eller (+)-bioton - Google Patents

Fremgangsmaade til fremstilling af en racemisk eller optisk aktiv (+)-thiolacton eller (+)-bioton

Info

Publication number
DK154563C
DK154563C DK607270A DK607270A DK154563C DK 154563 C DK154563 C DK 154563C DK 607270 A DK607270 A DK 607270A DK 607270 A DK607270 A DK 607270A DK 154563 C DK154563 C DK 154563C
Authority
DK
Denmark
Prior art keywords
thiolacton
bioton
racemic
preparing
procedure
Prior art date
Application number
DK607270A
Other languages
English (en)
Other versions
DK154563B (da
Inventor
Gerecke Max
Jean Pierre Zimmermann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK154563B publication Critical patent/DK154563B/da
Application granted granted Critical
Publication of DK154563C publication Critical patent/DK154563C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK607270A 1969-11-29 1970-11-27 Fremgangsmaade til fremstilling af en racemisk eller optisk aktiv (+)-thiolacton eller (+)-bioton DK154563C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1777369 1969-11-29
CH1777369A CH556867A (de) 1969-11-29 1969-11-29 Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons.

Publications (2)

Publication Number Publication Date
DK154563B DK154563B (da) 1988-11-28
DK154563C true DK154563C (da) 1989-04-17

Family

ID=4428001

Family Applications (1)

Application Number Title Priority Date Filing Date
DK607270A DK154563C (da) 1969-11-29 1970-11-27 Fremgangsmaade til fremstilling af en racemisk eller optisk aktiv (+)-thiolacton eller (+)-bioton

Country Status (10)

Country Link
US (1) US3740416A (da)
JP (1) JPS5327279B1 (da)
BE (1) BE759513A (da)
CA (1) CA982591A (da)
CH (1) CH556867A (da)
DK (1) DK154563C (da)
FR (1) FR2077540B1 (da)
GB (2) GB1320799A (da)
NL (1) NL156140B (da)
SE (1) SE391928B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054740A (en) * 1974-12-24 1977-10-18 Hoffmann-La Roche Inc. Hydroxybiotin
US4228295A (en) * 1977-02-23 1980-10-14 Hoffmann-La Roche Inc. Novel cycloheptathiophene intermediates for the synthesis of biotin
US4130713A (en) * 1977-08-05 1978-12-19 Hoffmann-La Roche Inc. Biotin intermediates
US4189586A (en) * 1977-08-05 1980-02-19 Hoffmann-La Roche Inc. Preparation of biotin
US4337345A (en) * 1977-08-05 1982-06-29 Hoffmann-La Roche Inc. Preparation of biotin via thieno [3,2c] isoxazoles
US4245104A (en) * 1978-12-01 1981-01-13 Hoffmann-La Roche Inc. Isoxazolines and isoxazolidines
US4284557A (en) * 1979-05-29 1981-08-18 Hoffmann-La Roche Inc. Intermediate racemates for the preparation of biotin and a process for their preparation
US4247704A (en) * 1979-05-29 1981-01-27 Hoffmann-La Roche Inc. Hexahydro thieno imadazole intermediates for the synthesis of biotin
US4537973A (en) * 1980-03-12 1985-08-27 Sumitomo Chemical Company, Limited Process for preparing biotin
DE3068160D1 (en) * 1980-03-14 1984-07-19 Sumitomo Chemical Co Process for preparing biotin
US4320056A (en) * 1980-05-15 1982-03-16 Hoffmann-La Roche Inc. Certain thia-diazatricyclo[3,3,3,08,11 ]tridecanes, and their preparation
US4382031A (en) * 1981-03-12 1983-05-03 Hoffmann-La Roche Inc. Intermediates for the preparation of biotin
DK43985A (da) * 1984-03-09 1985-09-10 Hoffmann La Roche Fremgangsmaade til fremstilling af heterocycliske forbindelser
DE4107121C1 (da) * 1991-03-06 1992-06-11 Merck Patent Gmbh, 6100 Darmstadt, De
CA2193774C (en) * 1995-12-26 2005-02-01 Norihiko Hirata Process for producing 1-hydroxythienoimidazole carboxylic acid and thienoimidazole carboxylic acid
DE10001317A1 (de) * 2000-01-14 2001-07-19 Merck Patent Gmbh Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien
TW200300676A (en) 2001-12-04 2003-06-16 Tanabe Seiyaku Co Biotin intermediate and its production
CN101096372B (zh) * 2007-01-24 2010-09-29 绍兴文理学院 硫内酯的合成工艺
CN102268007B (zh) * 2010-02-09 2015-11-25 浙江新和成股份有限公司 双苄生物素衍生物的制备方法
CN103788112B (zh) * 2012-11-02 2016-03-09 菏泽市方明制药有限公司 一种苄基生物素脱苄制备生物素的方法
CN103554129B (zh) * 2013-10-09 2016-03-23 安徽泰格维生素实业有限公司 一种生物素中间体硫酮的制备方法
CN107973806A (zh) * 2016-10-21 2018-05-01 大丰海嘉诺药业有限公司 一种制备d-生物素溴盐中间体的方法
WO2020110831A1 (ja) * 2018-11-28 2020-06-04 株式会社トクヤマ チオラクトン誘導体の製造方法
WO2021224295A1 (en) 2020-05-07 2021-11-11 Dsm Ip Assets B.V. A process for producing d-biotin intermediates
JP7665309B2 (ja) * 2020-10-21 2025-04-21 株式会社トクヤマ チオラクトン化合物の製造方法
WO2022257152A1 (en) 2021-06-11 2022-12-15 Dsm Ip Assets B.V. Process for producing biotin intermediate
CN116685567B (zh) * 2021-06-11 2024-11-19 株式会社德山 羟基噻吩并咪唑衍生物、乙烯基硫醚衍生物、正丁亚基硫醚衍生物、及饱和直链烃取代噻吩并咪唑衍生物的制造方法
EP4495123A1 (en) 2023-07-19 2025-01-22 DSM IP Assets B.V. An improved process for producing d-biotin intermediates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK71723C (da) * 1946-05-31 1950-11-20 Hoffmann La Roche Fremgangsmåde til fremstilling af d,1-biotin.
DK81470C (da) * 1947-07-24 1956-07-30 Hoffmann La Roche Fremgangsmåde til fremstilling af d- og l-biotin.
DK73837C (da) * 1947-07-24 1952-03-03 Hoffmann La Roche Fremgangsmåde til fremstilling af biotin eller homologe biotinforbindelser.

Also Published As

Publication number Publication date
FR2077540A1 (da) 1971-10-29
NL156140B (nl) 1978-03-15
US3740416A (en) 1973-06-19
GB1320798A (en) 1973-06-20
DE2058234A1 (de) 1971-06-09
SE391928B (sv) 1977-03-07
CH556867A (de) 1974-12-13
DK154563B (da) 1988-11-28
CA982591A (en) 1976-01-27
GB1320799A (en) 1973-06-20
DE2058234B2 (de) 1977-02-17
JPS5327279B1 (da) 1978-08-07
BE759513A (fr) 1971-05-27
FR2077540B1 (da) 1975-12-12
NL7015567A (da) 1971-06-02

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Legal Events

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PUP Patent expired