CH556867A - Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons. - Google Patents

Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons.

Info

Publication number
CH556867A
CH556867A CH1777369A CH1777369A CH556867A CH 556867 A CH556867 A CH 556867A CH 1777369 A CH1777369 A CH 1777369A CH 1777369 A CH1777369 A CH 1777369A CH 556867 A CH556867 A CH 556867A
Authority
CH
Switzerland
Prior art keywords
thiolactone
racemic
manufacturing
optically active
optically
Prior art date
Application number
CH1777369A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE759513D priority Critical patent/BE759513A/xx
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to CH1777369A priority patent/CH556867A/de
Priority to NL7015567.A priority patent/NL156140B/xx
Priority to US00090477A priority patent/US3740416A/en
Priority to CA098,432A priority patent/CA982591A/en
Priority to DE19702058234 priority patent/DE2058234C3/de
Priority to FR7042501A priority patent/FR2077540B1/fr
Priority to DK607270A priority patent/DK154563C/da
Priority to GB5640670A priority patent/GB1320798A/en
Priority to GB4870372A priority patent/GB1320799A/en
Priority to SE7016133A priority patent/SE391928B/xx
Priority to JP10451070A priority patent/JPS5327279B1/ja
Publication of CH556867A publication Critical patent/CH556867A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CH1777369A 1969-11-29 1969-11-29 Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons. CH556867A (de)

Priority Applications (12)

Application Number Priority Date Filing Date Title
BE759513D BE759513A (fr) 1969-11-29 Thiolactone
CH1777369A CH556867A (de) 1969-11-29 1969-11-29 Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons.
NL7015567.A NL156140B (nl) 1969-11-29 1970-10-23 Bereiding van racemisch of optisch actief (+)-cis-1,3-dibenzyl-hexahydro-1h-thieno(3,4-d)imidazool-2,4-dion en/of van (+)-biotine.
US00090477A US3740416A (en) 1969-11-29 1970-11-17 (+)-cis - 1,3-dibenzyl-hexahydro-1h-thieno-(3,4-d)imidazoles - 2,4-dione, and process for tis preparation
CA098,432A CA982591A (en) 1969-11-29 1970-11-18 Racemic and (+)-cis-1,3-dibenzyl-hexahydro-1h-thieno-(3,4-d)imidazole-2,4-dione
DE19702058234 DE2058234C3 (de) 1969-11-29 1970-11-26 (+Vcis-U-Dibenzyl-hexahydro-lH- thieno [3,4-d] imidazol-2,4-dion, Verfahren zu seiner Herstellung und dessen Verwendung
FR7042501A FR2077540B1 (de) 1969-11-29 1970-11-26
DK607270A DK154563C (da) 1969-11-29 1970-11-27 Fremgangsmaade til fremstilling af en racemisk eller optisk aktiv (+)-thiolacton eller (+)-bioton
GB5640670A GB1320798A (en) 1969-11-29 1970-11-27 Thiolactones and the preparation of biotin therefrom
GB4870372A GB1320799A (en) 1969-11-29 1970-11-27 Thieno-3,4-d-imidazole derivatives
SE7016133A SE391928B (sv) 1969-11-29 1970-11-27 Ny optiskt aktiv tiolaktion till anvendning vid syntes av (+)-biotin jemte forfarande for framstellning av tiolaktonen
JP10451070A JPS5327279B1 (de) 1969-11-29 1970-11-28

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1777369A CH556867A (de) 1969-11-29 1969-11-29 Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons.

Publications (1)

Publication Number Publication Date
CH556867A true CH556867A (de) 1974-12-13

Family

ID=4428001

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1777369A CH556867A (de) 1969-11-29 1969-11-29 Verfahren zur herstellung eines racemischen oder optisch aktiven thiolactons.

Country Status (10)

Country Link
US (1) US3740416A (de)
JP (1) JPS5327279B1 (de)
BE (1) BE759513A (de)
CA (1) CA982591A (de)
CH (1) CH556867A (de)
DK (1) DK154563C (de)
FR (1) FR2077540B1 (de)
GB (2) GB1320799A (de)
NL (1) NL156140B (de)
SE (1) SE391928B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054740A (en) * 1974-12-24 1977-10-18 Hoffmann-La Roche Inc. Hydroxybiotin
US4228295A (en) * 1977-02-23 1980-10-14 Hoffmann-La Roche Inc. Novel cycloheptathiophene intermediates for the synthesis of biotin
US4130713A (en) * 1977-08-05 1978-12-19 Hoffmann-La Roche Inc. Biotin intermediates
US4189586A (en) * 1977-08-05 1980-02-19 Hoffmann-La Roche Inc. Preparation of biotin
US4337345A (en) * 1977-08-05 1982-06-29 Hoffmann-La Roche Inc. Preparation of biotin via thieno [3,2c] isoxazoles
US4245104A (en) * 1978-12-01 1981-01-13 Hoffmann-La Roche Inc. Isoxazolines and isoxazolidines
US4284557A (en) * 1979-05-29 1981-08-18 Hoffmann-La Roche Inc. Intermediate racemates for the preparation of biotin and a process for their preparation
US4247704A (en) * 1979-05-29 1981-01-27 Hoffmann-La Roche Inc. Hexahydro thieno imadazole intermediates for the synthesis of biotin
US4537973A (en) * 1980-03-12 1985-08-27 Sumitomo Chemical Company, Limited Process for preparing biotin
DE3068160D1 (en) * 1980-03-14 1984-07-19 Sumitomo Chemical Co Process for preparing biotin
US4320056A (en) * 1980-05-15 1982-03-16 Hoffmann-La Roche Inc. Certain thia-diazatricyclo[3,3,3,08,11 ]tridecanes, and their preparation
US4382031A (en) * 1981-03-12 1983-05-03 Hoffmann-La Roche Inc. Intermediates for the preparation of biotin
DK43985A (da) * 1984-03-09 1985-09-10 Hoffmann La Roche Fremgangsmaade til fremstilling af heterocycliske forbindelser
DE4107121C1 (de) * 1991-03-06 1992-06-11 Merck Patent Gmbh, 6100 Darmstadt, De
CA2193774C (en) * 1995-12-26 2005-02-01 Norihiko Hirata Process for producing 1-hydroxythienoimidazole carboxylic acid and thienoimidazole carboxylic acid
DE10001317A1 (de) * 2000-01-14 2001-07-19 Merck Patent Gmbh Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien
TW200300676A (en) 2001-12-04 2003-06-16 Tanabe Seiyaku Co Biotin intermediate and its production
CN101096372B (zh) * 2007-01-24 2010-09-29 绍兴文理学院 硫内酯的合成工艺
CN102268007B (zh) * 2010-02-09 2015-11-25 浙江新和成股份有限公司 双苄生物素衍生物的制备方法
CN103788112B (zh) * 2012-11-02 2016-03-09 菏泽市方明制药有限公司 一种苄基生物素脱苄制备生物素的方法
CN103554129B (zh) * 2013-10-09 2016-03-23 安徽泰格维生素实业有限公司 一种生物素中间体硫酮的制备方法
CN107973806A (zh) * 2016-10-21 2018-05-01 大丰海嘉诺药业有限公司 一种制备d-生物素溴盐中间体的方法
JPWO2020110831A1 (ja) * 2018-11-28 2021-10-21 株式会社トクヤマ チオラクトン誘導体の製造方法
WO2021224295A1 (en) 2020-05-07 2021-11-11 Dsm Ip Assets B.V. A process for producing d-biotin intermediates
WO2022260168A1 (ja) * 2021-06-11 2022-12-15 株式会社トクヤマ ヒドロキシチエノイミダゾール誘導体、ビニルスルフィド誘導体、ｎ－ブチリデンスルフィド誘導体、及び飽和直鎖炭化水素置換チエノイミダゾール誘導体の製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK71723C (da) * 1946-05-31 1950-11-20 Hoffmann La Roche Fremgangsmåde til fremstilling af d,1-biotin.
DK73837C (da) * 1947-07-24 1952-03-03 Hoffmann La Roche Fremgangsmåde til fremstilling af biotin eller homologe biotinforbindelser.
DK81470C (da) * 1947-07-24 1956-07-30 Hoffmann La Roche Fremgangsmåde til fremstilling af d- og l-biotin.

Also Published As

Publication number Publication date
FR2077540B1 (de) 1975-12-12
US3740416A (en) 1973-06-19
NL156140B (nl) 1978-03-15
BE759513A (fr) 1971-05-27
DE2058234A1 (de) 1971-06-09
SE391928B (sv) 1977-03-07
NL7015567A (de) 1971-06-02
CA982591A (en) 1976-01-27
FR2077540A1 (de) 1971-10-29
GB1320799A (en) 1973-06-20
DE2058234B2 (de) 1977-02-17
DK154563C (da) 1989-04-17
GB1320798A (en) 1973-06-20
DK154563B (da) 1988-11-28
JPS5327279B1 (de) 1978-08-07

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Legal Events

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