SE368954B - - Google Patents

Info

Publication number
SE368954B
SE368954B SE03074/71A SE307471A SE368954B SE 368954 B SE368954 B SE 368954B SE 03074/71 A SE03074/71 A SE 03074/71A SE 307471 A SE307471 A SE 307471A SE 368954 B SE368954 B SE 368954B
Authority
SE
Sweden
Application number
SE03074/71A
Inventor
J Bourquin
G Schwarb
E Waldvogel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH359870A external-priority patent/CH533639A/de
Priority claimed from CH1412070A external-priority patent/CH537404A/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE368954B publication Critical patent/SE368954B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C07D333/80Seven-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
SE03074/71A 1970-03-11 1971-03-10 SE368954B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH359870A CH533639A (de) 1970-03-11 1970-03-11 Verfahren zur Herstellung neuer Benzo(4,5)cyclohepta(1,2-b)-thiophen-Derivate
CH1159370A CH531000A (de) 1970-03-11 1970-07-31 Verfahren zur Herstellung neuer Benzocycloheptathiophene
CH1412070A CH537404A (de) 1970-09-24 1970-09-24 Verfahren zur Herstellung neuer Thiophenderivate
CH163271 1971-02-04

Publications (1)

Publication Number Publication Date
SE368954B true SE368954B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-07-29

Family

ID=27428249

Family Applications (2)

Application Number Title Priority Date Filing Date
SE03074/71A SE368954B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-03-11 1971-03-10
SE7111154A SE378820B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-03-11 1971-09-03

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7111154A SE378820B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1970-03-11 1971-09-03

Country Status (12)

Country Link
US (4) US3682930A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (2) AT319238B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (2) BE764019A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (2) CA960673A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH531000A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE2111071C3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (2) FR2085695B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (4) GB1355537A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (2) LU62757A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (2) NL167431C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
OA (2) OA03692A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (2) SE368954B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH531000A (de) * 1970-03-11 1972-11-30 Sandoz Ag Verfahren zur Herstellung neuer Benzocycloheptathiophene
BE794377A (fr) * 1972-01-24 1973-07-23 Sandoz Sa Nouveaux derives du benzo-cyclohepta-thiophene
US3960894A (en) * 1972-01-24 1976-06-01 Sandoz Ltd. 9-Bromo-or chloro-9,10-dihydro-10-dihydro-10-alkoxy-4H-benzo[4,5]cyclo-hepta[1,2-b]thiophen-4-ones
US4072756A (en) * 1973-05-17 1978-02-07 Sandoz Ltd. Tricyclo piperidino ketones and soporific compositions thereof
CA1041100A (en) * 1973-10-04 1978-10-24 Herbert G. Johnson Pyridine-diyldioxamic acid and derivatives
CH580621A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1973-10-08 1976-10-15 Sandoz Ag
US4073915A (en) * 1975-05-20 1978-02-14 Sandoz Ltd. Treating asthma
FI761607A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1975-06-16 1976-12-17 Sandoz Ag
US4128549A (en) * 1976-02-27 1978-12-05 Sandoz Ltd. Precursors of 4-(1-alkyl-4-piperidylidene-4H-benzo[4,5]cyclohepta-[1,2-b]thiophen-10(9H)-ones
US4282233B1 (en) * 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
HU202753B (en) * 1986-06-21 1991-04-29 Sandoz Ag Process for producing retard pharmaceutical compositions containing cetotiphene
US5089496A (en) * 1986-10-31 1992-02-18 Schering Corporation Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies
US5438062A (en) * 1986-10-31 1995-08-01 Schering Corporation Benzo(5,6)cycloheptapyridines, compositions and methods of use
DZ1460A1 (fr) * 1989-11-22 2004-09-13 Sod Conseils Rech Applic Nouveaux dérivés du sélénophèn ainsi que leur procédé de préparation.
CA2038417A1 (en) * 1990-04-11 1991-10-12 Yasuo Ito Piperidine compounds, method for preparation thereof, and a pharmaceutical composition comprising the same
DE69110685T2 (de) * 1990-10-10 1995-11-09 Schering Corp Substituierte imidazobenzazepine und imidazopyridoazepine.
US5891460A (en) * 1995-06-07 1999-04-06 University Of Southern California University Park Campus Method for reducing or preventing post-surgical adhesion formation using ketotifen and analogs thereof
US6207684B1 (en) 1997-06-09 2001-03-27 Bridge Pharma, Inc. Compounds with combined antihistaminic and mast cell stabilizing activities, intended for ophthalmic use
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
EP1218007B1 (en) * 1999-09-13 2011-07-20 Bridge Pharma, Inc. Optically active isomers of ketotifen and therapeutically active metabolites thereof
AU5139800A (en) * 1999-12-01 2001-06-12 Klein Pharmaceuticals Topical administration of ketotifen
US20030212078A1 (en) * 2001-05-17 2003-11-13 Klein Gerald L. Topical administration of pharmacological compositions for non-systemic treatment of pruritus
JP4996241B2 (ja) * 2003-01-14 2012-08-08 ギリアード サイエンシーズ, インコーポレイテッド 組み合わせ抗ウイルス治療のための組成物および方法
CN100381439C (zh) * 2005-04-05 2008-04-16 浙江华海药业股份有限公司 9,10-二溴-9,10-二氢-4-H苯并[4,5]环庚烯并[1,2-b]噻吩-4-酮的制备方法
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
WO2008153761A1 (en) * 2007-05-23 2008-12-18 Mastcell Pharmaceuticals, Inc. Methods
MX2010008400A (es) 2008-01-30 2010-08-23 Nippon Zoki Pharmaceutical Co Derivado de piperidina.
WO2009142772A2 (en) 2008-05-23 2009-11-26 Mastcell Pharmaceuticals, Inc. Methods and treatment for allergies and inflammation associated with gastrointestinal diseases
US8653285B2 (en) * 2008-08-01 2014-02-18 Nippon Zoki Pharmaceutical Co., Ltd. Aminopropylidene derivative
KR20120037913A (ko) * 2009-07-28 2012-04-20 니폰 조키 세야쿠 가부시키가이샤 티아벤조아줄렌프로피온산 유도체의 제조법
WO2013063512A1 (en) 2011-10-28 2013-05-02 Lumena Pharmaceuticals, Inc Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases
BR112014010228B1 (pt) 2011-10-28 2020-09-29 Lumena Pharmaceuticals Llc Uso de inibidores de reciclagem de ácido biliar para o tratamento de hipercolemia e doença hepática colestática
US8778971B2 (en) 2012-10-23 2014-07-15 Bridge Pharma, Inc. Medicinal treatment of dermal diseases in companion animals
US8557846B1 (en) 2012-10-23 2013-10-15 Bridge Pharma, Inc. Medicinal treatment of dermal diseases in dogs
US20140120121A1 (en) 2012-10-30 2014-05-01 Bridge Pharma, Inc. Medicinal treatment of atopic inflammatory diseases
US20150272941A1 (en) 2012-10-30 2015-10-01 Bridge Pharma, Inc. Medicinal treatment of chronic pulmonary inflammatory diseases with norketotifen
US9138431B2 (en) 2013-08-06 2015-09-22 Bridge Pharma, Inc. Methods of treatment of histamine H-4 receptor-related pruritus
US9345697B2 (en) 2013-08-06 2016-05-24 Bridge Pharma, Inc. Methods of treatment of non-histaminic pruritus
US9439895B2 (en) 2013-08-06 2016-09-13 Bridge Pharma, Inc. Methods of treating pruritic conditions mediated through non-histaminergic mechanisms in diabetic patients
ES2703693T3 (es) 2015-06-11 2019-03-12 Bridge Pharma Inc Métodos de tratamiento del prurito no histamínico en mamíferos
MX2018011699A (es) 2018-09-26 2019-07-24 Federico Amezcua Amezcua Composicion farmaceutica sinergica de un antagonista de los receptores de leucotrienos y un agonista inverso de la histamina h1.
US10959992B2 (en) 2019-02-22 2021-03-30 Bridge Pharma Inc. Methods of treatment of asthma and COPD

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL297097A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1962-08-31
US3491103A (en) * 1963-12-19 1970-01-20 Sandoz Ag Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
FR1437412A (fr) * 1963-12-19 1966-05-06 Sandoz Sa Nouveaux benzo-cyclohepta-thiophènes et leur préparation
GB1084450A (en) * 1963-12-20 1967-09-20 Sandoz Ltd Improvements in or relating to 4h-benzo[4,5]cyclohepta-[1,2-b] thiophene derivatives
CH537897A (de) * 1968-03-20 1973-06-15 Hoffmann La Roche Verfahren zur Herstellung von tricyclischen Verbindungen
US3574199A (en) * 1968-06-28 1971-04-06 Searle & Co 6-(aminoalkyl- and aminoalkylidene)-1,1a,6,10b -tetrahydro-dibenzo(a,e)cyclopropa(c)cycloheptenes
CH531000A (de) * 1970-03-11 1972-11-30 Sandoz Ag Verfahren zur Herstellung neuer Benzocycloheptathiophene
US3709947A (en) * 1971-07-26 1973-01-09 Searle & Co 6-chloropropylidene-1,1a,6,10b-tetrahydrobenzo(a,e)cyclopropa(c)cycloheptenes

Also Published As

Publication number Publication date
BE771964A (fr) 1972-02-29
DE2111071A1 (de) 1971-09-23
US3749786A (en) 1973-07-31
GB1355539A (en) 1974-06-05
SE378820B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-09-15
CA947767A (en) 1974-05-21
NL171449C (nl) 1983-04-05
FR2085695A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-12-31
FR2107917B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-04-18
DE2111071C3 (de) 1979-07-12
US3682930A (en) 1972-08-08
FR2085695B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-11-15
DE2144490A1 (de) 1972-03-30
DE2111071B2 (de) 1978-11-09
US3853915A (en) 1974-12-10
AT319238B (de) 1974-12-10
GB1355537A (en) 1974-06-05
GB1360219A (en) 1974-07-17
NL7111808A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1972-03-28
FR2107917A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1972-05-12
BE764019A (fr) 1971-09-09
CA960673A (en) 1975-01-07
NL167431C (nl) 1981-12-16
NL7103174A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-09-14
LU63829A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1972-06-27
OA03786A (fr) 1971-12-24
CH531000A (de) 1972-11-30
AT321905B (de) 1975-04-25
OA03692A (fr) 1971-12-24
US3770728A (en) 1973-11-06
GB1355538A (en) 1974-06-05
LU62757A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1971-10-13

Similar Documents

Publication Publication Date Title
FR2107917B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2044470A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1716970A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1517670A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1833270A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2017870A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2085370A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2130570A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU442396B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1918570A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2119370A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1581370A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2144270A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1591370A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1603270A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2131570A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2130770A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1689770A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1789870A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1841070A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1974970A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1872870A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2115870A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU2112570A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU1879170A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)