SE354851B - - Google Patents
Info
- Publication number
- SE354851B SE354851B SE02050/70A SE205070A SE354851B SE 354851 B SE354851 B SE 354851B SE 02050/70 A SE02050/70 A SE 02050/70A SE 205070 A SE205070 A SE 205070A SE 354851 B SE354851 B SE 354851B
- Authority
- SE
- Sweden
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
- C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
- C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/22—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/02—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms
- C07C317/10—Sulfones; Sulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
- C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Glass Compositions (AREA)
Priority Applications (30)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE02050/70A SE354851B (fi) | 1970-02-18 | 1970-02-18 | |
| ZA710682A ZA71682B (en) | 1970-02-18 | 1971-02-03 | New phenoxy-hydroxypropylamines and their preparation |
| BE762629A BE762629A (fr) | 1970-02-18 | 1971-02-08 | Nouvelles phenoxy-hydroxypropylamines et methode pour leur preparation |
| DE2106209A DE2106209C3 (de) | 1970-02-18 | 1971-02-10 | p-substituierte Phenoxypropanolamine, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis AB Hässle, Mölndal (Schweden) |
| NL7101885.A NL160549C (nl) | 1970-02-18 | 1971-02-12 | Werkwijze voor de bereiding van een farmaceutisch preparaat met hart-selectieve beta -receptor blokkerende werking, gevormd preparaat, verkregen volgens deze werkwijze, als- mede werkwijze voor het bereiden van nieuwe 1-alkylamino-3-(gesubstitueerd fenoxy)-propanol-2-verbin- dingen en zuuradditiezouten daarvan met beta -receptor blokkerende werking. |
| CH278775A CH572896A5 (fi) | 1970-02-18 | 1971-02-16 | |
| CH278575A CH578507A5 (fi) | 1970-02-18 | 1971-02-16 | |
| CH221671A CH563338A5 (fi) | 1970-02-18 | 1971-02-16 | |
| FR7105224A FR2081523B1 (fi) | 1970-02-18 | 1971-02-16 | |
| CH278975A CH576938A5 (fi) | 1970-02-18 | 1971-02-16 | |
| CH178074A CH563340A5 (fi) | 1970-02-18 | 1971-02-16 | |
| NO564/71A NO132798C (fi) | 1970-02-18 | 1971-02-16 | |
| CH278675A CH572895A5 (fi) | 1970-02-18 | 1971-02-16 | |
| CH278875A CH572897A5 (fi) | 1970-02-18 | 1971-02-16 | |
| CH177974A CH563339A5 (fi) | 1970-02-18 | 1971-02-16 | |
| AT957072A AT317181B (de) | 1970-02-18 | 1971-02-17 | Verfahren zur Herstellung von neuen 1-Isopropylamino-2-hydroxy-3-(p-substituierten phenoxy)-propanen in Form der Racemate und optischen Antipoden sowie von Säureadditionssalzen derselben |
| AT134971A AT307386B (de) | 1970-02-18 | 1971-02-17 | Verfahren zur Herstellung von neuen 1-Isopropylamino- oder 1-tert. Butylamino-2-hydroxy-3-(p-substituierten phenoxy)-propanen, sowie deren Säureadditionssalzen |
| DK71971AA DK129446B (da) | 1970-02-18 | 1971-02-17 | Analogifremgangsmåde til fremstilling af fenoxyhydroxypropylaminer eller syreadditionssalte heraf. |
| IE184/71A IE35106B1 (en) | 1970-02-18 | 1971-02-17 | Phenoxy-hydroxypropylamines and their preparation |
| FI452/71A FI55024C (fi) | 1970-02-18 | 1971-02-17 | Analogifoerfarande foer framstaellning av substituerade fenoxypropanolaminer med beta-receptor blockerande aktivitet samt farmaceutiskt acceptabla ogiftiga syraadditionssalter daerav |
| AT505872A AT310144B (de) | 1970-02-18 | 1971-02-17 | Verfahren zur Herstellung von neuen 1-Isopropylamino- oder 1-tert. Butylamino-2-hydroxy-3-(p-substituierten phenoxy)-propanen in Form der Racemate und optischen Antipoden sowie von Säureadditionssalzen derselben |
| CA105,683A CA982140A (en) | 1970-02-18 | 1971-02-18 | Phenoxy-hydroxypropylamines and their preparation |
| JP731771A JPS5317587B1 (fi) | 1970-02-18 | 1971-02-18 | |
| GB2199471A GB1308106A (en) | 1970-02-18 | 1971-04-19 | Phenoxyhydroxypropylamines and their preparation |
| US342749A US3873600A (en) | 1970-02-18 | 1973-03-19 | Phenoxycarbamates |
| US433450A US3928601A (en) | 1970-02-18 | 1974-01-15 | Phenoxy-hydroxypropylamines, method and pharmaceutical preparations for treating cardiovascular diseases |
| US433565A US3876802A (en) | 1970-02-18 | 1974-01-15 | Phenoxy-hydroxypropylamines, method and pharmaceutical preparations for treating cardiovascular diseases |
| US05/433,451 US3998790A (en) | 1970-02-18 | 1974-01-15 | Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases |
| MY161/75A MY7500161A (en) | 1970-02-18 | 1975-12-30 | Phenoxy-hydroxypropylamines and their preparation |
| JP14106877A JPS53101322A (en) | 1970-02-18 | 1977-11-24 | Process for preparing phenoxyy hydroxypropylamine compound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE02050/70A SE354851B (fi) | 1970-02-18 | 1970-02-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE354851B true SE354851B (fi) | 1973-03-26 |
Family
ID=20259298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE02050/70A SE354851B (fi) | 1970-02-18 | 1970-02-18 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US3873600A (fi) |
| JP (2) | JPS5317587B1 (fi) |
| AT (3) | AT317181B (fi) |
| BE (1) | BE762629A (fi) |
| CA (1) | CA982140A (fi) |
| CH (8) | CH572896A5 (fi) |
| DE (1) | DE2106209C3 (fi) |
| DK (1) | DK129446B (fi) |
| FI (1) | FI55024C (fi) |
| FR (1) | FR2081523B1 (fi) |
| GB (1) | GB1308106A (fi) |
| IE (1) | IE35106B1 (fi) |
| MY (1) | MY7500161A (fi) |
| NL (1) | NL160549C (fi) |
| NO (1) | NO132798C (fi) |
| SE (1) | SE354851B (fi) |
| ZA (1) | ZA71682B (fi) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE384853B (sv) * | 1972-04-04 | 1976-05-24 | Haessle Ab | Forfarande for framstellning av nya aminer |
| US4145442A (en) * | 1972-04-04 | 1979-03-20 | Aktiebolaget Hassle | Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases |
| US4035420A (en) * | 1972-07-06 | 1977-07-12 | Aktiebolaget Hassle | Substituted ureido alkylene phenoxy propanolamines |
| US4041075A (en) * | 1973-12-12 | 1977-08-09 | Imperial Chemical Industries Limited | Phenoxy-alkanolamine derivatives |
| AT334385B (de) * | 1973-12-20 | 1976-01-10 | Chemie Linz Ag | Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen |
| SE7402096L (fi) * | 1974-02-18 | 1975-08-19 | United Aircraft Corp | |
| US4145363A (en) * | 1975-02-05 | 1979-03-20 | Yamanouchi Pharmaceutical Co., Ltd. | 4-Carbamoylamino-α-aminomethylbenzyl alcohol derivatives |
| FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
| DE2645710C2 (de) * | 1976-10-09 | 1985-06-27 | Merck Patent Gmbh, 6100 Darmstadt | Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung |
| IT1109002B (it) * | 1977-09-22 | 1985-12-16 | Menarini Sas | Derivati del 2 oxazolidone e loro metodi di preparazione |
| US4243681A (en) * | 1977-10-11 | 1981-01-06 | Mead Johnson & Company | Alkylthiophenoxypropanolamines and pharmaceutical compositions and uses thereof |
| US4341718A (en) * | 1978-07-03 | 1982-07-27 | American Home Products Corporation | α-[(Alkylamino)-methyl]-β-aryloxy-benzeneethanols exhibiting antiarrhythmic activity |
| US4329502A (en) * | 1978-08-28 | 1982-05-11 | Syva Company | Propranolol antigen conjugates and antibodies |
| FR2477537A1 (fr) * | 1980-03-07 | 1981-09-11 | Francaise Sucrerie | Nouvelles guanidines acylees, urees et urees substituees, leur procede de fabrication et leur application en tant que medicaments |
| FI59985C (fi) * | 1980-05-26 | 1982-01-08 | Farmos Oy | Foerfarande foer framstaellning av terapeutiskt aktiv 1-isopropylamino-3-(4-(2-metoxietyl)fenoxi)-2-propanol samt dess syra-additionssalter |
| SE8004088L (sv) * | 1980-06-02 | 1981-12-03 | Haessle Ab | Nya substituerade 3-fenoxi-l-alkoxikarbonylalkylamino-propanol-2-er med beta-receptorblockerande egenskaper samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma och metod att ... |
| SE8004087L (sv) * | 1980-06-02 | 1981-12-03 | Haessle Ab | Nya parasubstituerade 3-fenoxi-1-alkylaminopropanol-2-er med betareceptorblockerande egenskaper, samt forfarande for deras framstellning, farmaceutiska beredningar innehallande desamma, och metod att behandla akut ... |
| FI63016C (fi) * | 1980-06-04 | 1983-04-11 | Haessle Ab | Foerfarande foer framstaellning av en terapeutiskt aktiv propanolamin |
| US4342783A (en) * | 1980-06-30 | 1982-08-03 | Synthelabo | Anti-glaucoma agent |
| FR2497194B1 (fr) * | 1980-08-07 | 1985-06-14 | Sandoz Sa | Nouveaux composes phenoliques |
| CH643527A5 (en) * | 1980-10-24 | 1984-06-15 | Ciba Geigy Ag | Process for the preparation of 1-alkylamino-3-(4-(2-lower alkoxy-ethyl)phenoxy)-2-propanols |
| DE3151201A1 (de) * | 1981-12-23 | 1983-07-28 | Beiersdorf Ag, 2000 Hamburg | Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte |
| US4450172A (en) * | 1982-03-10 | 1984-05-22 | E. I. Du Pont De Nemours And Company | Antihypertensive polyhalohydroxyisopropyl phenylalka(e)noic acid esters of alkylaminohydroxypropyloxyphenylalkyl alcohols |
| DE3210061A1 (de) * | 1982-03-19 | 1983-09-22 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von propafenon |
| SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
| US5081154A (en) * | 1984-01-10 | 1992-01-14 | Aktiebolaget Hassle | Metoprolol succinate |
| FR2568249B1 (fr) * | 1984-07-25 | 1986-12-05 | Lipha | Amino-1 aryloxy-3 propanols-2, procedes de preparation et medicaments les contenant |
| GB8519154D0 (en) * | 1985-07-30 | 1985-09-04 | Ici Plc | Aromatic ethers |
| US5008288A (en) * | 1986-01-06 | 1991-04-16 | Alfred Stracher | Carnitine directed pharmaceutical agents |
| US4866040A (en) * | 1986-01-06 | 1989-09-12 | Alfred Stracher | Aminocarnitine directed pharmaceutical agents |
| WO1988000190A1 (en) * | 1986-06-25 | 1988-01-14 | Massachusetts Institute Of Technology | Optically active derivatives of glycidol |
| JPS6388944U (fi) * | 1986-12-01 | 1988-06-09 | ||
| JPS6445265A (en) * | 1987-08-06 | 1989-02-17 | Kotobukiya Goushi | Lidded box having socket and spigot part and its manufacture |
| ES2011584A6 (es) * | 1989-05-26 | 1990-01-16 | Esteve Quimica Sa | Procedimiento industrial para la obtencion de una ariloxipropanolamina. |
| GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
| US5107034A (en) * | 1990-03-28 | 1992-04-21 | Hoechst Celanese Corporation | Method for producing 4-(2'-methoxyethyl)phenol |
| ES2065291B1 (es) * | 1993-07-30 | 1995-10-01 | Prodesfarma Sa | "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente" |
| US5859390A (en) * | 1996-10-23 | 1999-01-12 | Hill-Rom, Inc. | Hospital bed scale mounting apparatus |
| US5998458A (en) * | 1997-06-25 | 1999-12-07 | University Technology Corporation | Method of treating heart failure |
| KR100469946B1 (ko) * | 1998-04-14 | 2005-05-17 | 삼성정밀화학 주식회사 | 키랄(s)-2,3-치환-1-프로필아민유도체의제조방법 |
| KR100489649B1 (ko) * | 1998-04-14 | 2005-09-02 | 삼성정밀화학 주식회사 | (s)-3-치환-2-히드록시프로필아민의제조방법 |
| KR100469947B1 (ko) * | 1998-04-14 | 2005-04-08 | 삼성정밀화학 주식회사 | 키랄(s)-3-아미노-1,2-프로판디올의제조방법 |
| US6924441B1 (en) | 1999-09-29 | 2005-08-02 | Hill-Rom Services, Inc. | Load cell apparatus |
| SE0100824D0 (sv) * | 2001-03-09 | 2001-03-09 | Astrazeneca Ab | Method III to obtain microparticles |
| AP2005003232A0 (en) | 2002-08-19 | 2005-03-31 | Pfizer Prod Inc | Combination therapy for hyperproliferative diseases. |
| JP4901474B2 (ja) | 2003-05-30 | 2012-03-21 | ランバクシー ラボラトリーズ リミテッド | 置換ピロール誘導体 |
| US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
| US7176391B2 (en) * | 2004-09-13 | 2007-02-13 | Hill-Rom Services, Inc. | Load cell to frame interface for hospital bed |
| NZ560386A (en) * | 2005-01-31 | 2009-12-24 | Mylan Lab Inc | Pharmaceutical composition comprising hydroxylated nebivolol |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| KR101329112B1 (ko) | 2005-11-08 | 2013-11-14 | 랜박시 래보러터리스 리미티드 | (3ｒ,5ｒ)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법 |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| ES2382009T3 (es) | 2006-12-01 | 2012-06-04 | Bristol-Myers Squibb Company | Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares |
| WO2008112287A1 (en) | 2007-03-12 | 2008-09-18 | Nektar Therapeutics | Oligomer-beta blocker conjugates |
| EP2050441A1 (en) | 2007-10-19 | 2009-04-22 | Université Victor Segalen Bordeaux 2 | Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| US8987262B2 (en) | 2007-10-19 | 2015-03-24 | Universite de Bordeaux | Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas |
| CN102381995B (zh) * | 2010-08-31 | 2015-04-15 | 扬子江药业集团北京海燕药业有限公司 | 美托洛尔的制备方法 |
| CN102295569B (zh) * | 2011-07-04 | 2014-05-21 | 南京工业大学 | 一种制备(s)-琥珀酸美托洛尔的方法 |
| CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| WO2020150473A2 (en) | 2019-01-18 | 2020-07-23 | Dogma Therapeutics, Inc. | Pcsk9 inhibitors and methods of use thereof |
| CN112645827A (zh) * | 2020-12-25 | 2021-04-13 | 浙江普洛家园药业有限公司 | 一种连续合成美多心安及其盐的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1220440B (de) * | 1962-02-14 | 1966-07-07 | Sanol Arznei Schwarz Gmbh | Verfahren zur Herstellung von Derivaten des 1-(o-Bromphenoxy)-2-hydroxy-3-amino-propans und deren Saeureadditionssalzen |
| GB1199037A (en) * | 1967-09-27 | 1970-07-15 | Ici Ltd | Alkanolamine Derivatives |
| US3466325A (en) * | 1965-04-30 | 1969-09-09 | Haessle Ab | 1-(ortho-alkenyl phenoxy) - 2-hydroxy-3-isopropylaminopropanes and the salts thereof |
| US3637827A (en) * | 1966-01-06 | 1972-01-25 | Smith Kline French Lab | Benzhydryloxy-cyclopropanecarboxylic acids and amides |
| US3541130A (en) * | 1967-02-06 | 1970-11-17 | Boehringer Sohn Ingelheim | 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes |
| DE1937477C3 (de) * | 1969-07-23 | 1980-04-10 | C.H. Boehringer Sohn, 6507 Ingelheim | I -Phenoxy-2-hydroxy-3-(l -methylcycloalkylamino)-propane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| JPS5247447A (en) * | 1975-09-29 | 1977-04-15 | Touhoku Nougiyou Shikenjiyouch | Blue film utilizing method for growing of paddy rice young plant |
-
1970
- 1970-02-18 SE SE02050/70A patent/SE354851B/xx unknown
-
1971
- 1971-02-03 ZA ZA710682A patent/ZA71682B/xx unknown
- 1971-02-08 BE BE762629A patent/BE762629A/xx not_active IP Right Cessation
- 1971-02-10 DE DE2106209A patent/DE2106209C3/de not_active Expired
- 1971-02-12 NL NL7101885.A patent/NL160549C/xx not_active IP Right Cessation
- 1971-02-16 CH CH278775A patent/CH572896A5/xx not_active IP Right Cessation
- 1971-02-16 NO NO564/71A patent/NO132798C/no unknown
- 1971-02-16 CH CH278575A patent/CH578507A5/xx not_active IP Right Cessation
- 1971-02-16 CH CH278875A patent/CH572897A5/xx not_active IP Right Cessation
- 1971-02-16 CH CH278975A patent/CH576938A5/xx not_active IP Right Cessation
- 1971-02-16 FR FR7105224A patent/FR2081523B1/fr not_active Expired
- 1971-02-16 CH CH178074A patent/CH563340A5/xx not_active IP Right Cessation
- 1971-02-16 CH CH278675A patent/CH572895A5/xx not_active IP Right Cessation
- 1971-02-16 CH CH221671A patent/CH563338A5/xx not_active IP Right Cessation
- 1971-02-16 CH CH177974A patent/CH563339A5/xx not_active IP Right Cessation
- 1971-02-17 AT AT957072A patent/AT317181B/de active
- 1971-02-17 AT AT505872A patent/AT310144B/de not_active IP Right Cessation
- 1971-02-17 FI FI452/71A patent/FI55024C/fi active
- 1971-02-17 DK DK71971AA patent/DK129446B/da not_active IP Right Cessation
- 1971-02-17 AT AT134971A patent/AT307386B/de not_active IP Right Cessation
- 1971-02-17 IE IE184/71A patent/IE35106B1/xx unknown
- 1971-02-18 JP JP731771A patent/JPS5317587B1/ja active Pending
- 1971-02-18 CA CA105,683A patent/CA982140A/en not_active Expired
- 1971-04-19 GB GB2199471A patent/GB1308106A/en not_active Expired
-
1973
- 1973-03-19 US US342749A patent/US3873600A/en not_active Expired - Lifetime
-
1974
- 1974-01-15 US US05/433,451 patent/US3998790A/en not_active Expired - Lifetime
- 1974-01-15 US US433450A patent/US3928601A/en not_active Expired - Lifetime
- 1974-01-15 US US433565A patent/US3876802A/en not_active Expired - Lifetime
-
1975
- 1975-12-30 MY MY161/75A patent/MY7500161A/xx unknown
-
1977
- 1977-11-24 JP JP14106877A patent/JPS53101322A/ja active Granted