SE0401971D0 - Piperidne derivatives - Google Patents

Piperidne derivatives

Info

Publication number
SE0401971D0
SE0401971D0 SE0401971A SE0401971A SE0401971D0 SE 0401971 D0 SE0401971 D0 SE 0401971D0 SE 0401971 A SE0401971 A SE 0401971A SE 0401971 A SE0401971 A SE 0401971A SE 0401971 D0 SE0401971 D0 SE 0401971D0
Authority
SE
Sweden
Prior art keywords
piperidne
derivatives
sup
compounds
enantiomers
Prior art date
Application number
SE0401971A
Other languages
English (en)
Swedish (sv)
Inventor
James Folmer
Fraser Hunt
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0401971A priority Critical patent/SE0401971D0/xx
Publication of SE0401971D0 publication Critical patent/SE0401971D0/xx
Priority to US11/572,967 priority patent/US20080064706A1/en
Priority to RU2007105970/04A priority patent/RU2007105970A/ru
Priority to PCT/SE2005/001189 priority patent/WO2006014136A1/en
Priority to AU2005267932A priority patent/AU2005267932A1/en
Priority to MX2007001226A priority patent/MX2007001226A/es
Priority to EP05761797A priority patent/EP1781613A1/en
Priority to BRPI0514035-8A priority patent/BRPI0514035A/pt
Priority to JP2007524768A priority patent/JP2008508353A/ja
Priority to CA002576112A priority patent/CA2576112A1/en
Priority to CNA2005800262732A priority patent/CN1993325A/zh
Priority to KR1020077002643A priority patent/KR20070043998A/ko
Priority to IL180548A priority patent/IL180548A0/en
Priority to ZA200700683A priority patent/ZA200700683B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE0401971A 2004-08-02 2004-08-02 Piperidne derivatives SE0401971D0 (sv)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SE0401971A SE0401971D0 (sv) 2004-08-02 2004-08-02 Piperidne derivatives
KR1020077002643A KR20070043998A (ko) 2004-08-02 2005-07-27 히스타민 ｈ3 수용체 리간드로서의 피페리딘 유도체
EP05761797A EP1781613A1 (en) 2004-08-02 2005-07-27 Piperidine derivatives as histamine h3 receptor ligands
RU2007105970/04A RU2007105970A (ru) 2004-08-02 2005-07-27 Пиперидиновые производные в качестве лигандов гистаминового из рецептора
PCT/SE2005/001189 WO2006014136A1 (en) 2004-08-02 2005-07-27 Piperidine derivatives as histamine h3 receptor ligands
AU2005267932A AU2005267932A1 (en) 2004-08-02 2005-07-27 Piperidine derivatives as histamine H3 receptor ligands
MX2007001226A MX2007001226A (es) 2004-08-02 2005-07-27 Derivados de piperidina como ligandos del receptor de histamina h3.
US11/572,967 US20080064706A1 (en) 2004-08-02 2005-07-27 Piperidine Derivatives as Histamine H3 Receptor Ligands
BRPI0514035-8A BRPI0514035A (pt) 2004-08-02 2005-07-27 composto, sais farmaceuticamente aceitáveis do mesmo, diastereÈmeros, enanciÈmeros ou misturas do mesmo, uso de um composto, composição farmacêutica, método para a terapia de depressão em um animal de sangue quente, e, processo para preparar um composto
JP2007524768A JP2008508353A (ja) 2004-08-02 2005-07-27 ヒスタミンｈ３受容体リガンドとしてのピペリジン誘導体
CA002576112A CA2576112A1 (en) 2004-08-02 2005-07-27 Piperidine derivatives as histamine h3 receptor ligands
CNA2005800262732A CN1993325A (zh) 2004-08-02 2005-07-27 作为组胺h3受体配体的哌啶衍生物
IL180548A IL180548A0 (en) 2004-08-02 2007-01-04 Piperidine derivatives as histamine h3 receptor ligands
ZA200700683A ZA200700683B (en) 2004-08-02 2007-01-24 Piperidine derivatives as histamine H3 receptor ligands

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0401971A SE0401971D0 (sv) 2004-08-02 2004-08-02 Piperidne derivatives

Publications (1)

Publication Number Publication Date
SE0401971D0 true SE0401971D0 (sv) 2004-08-02

Family

ID=32906883

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0401971A SE0401971D0 (sv) 2004-08-02 2004-08-02 Piperidne derivatives

Country Status (14)

Country Link
US (1) US20080064706A1 (ja)
EP (1) EP1781613A1 (ja)
JP (1) JP2008508353A (ja)
KR (1) KR20070043998A (ja)
CN (1) CN1993325A (ja)
AU (1) AU2005267932A1 (ja)
BR (1) BRPI0514035A (ja)
CA (1) CA2576112A1 (ja)
IL (1) IL180548A0 (ja)
MX (1) MX2007001226A (ja)
RU (1) RU2007105970A (ja)
SE (1) SE0401971D0 (ja)
WO (1) WO2006014136A1 (ja)
ZA (1) ZA200700683B (ja)

Families Citing this family (39)

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EP1608319A4 (en) 2003-04-03 2007-02-28 Univ California IMPROVED HEMMER FOR SOLUBLE EPOXY HYDROLASE
US20090018092A1 (en) 2004-03-16 2009-01-15 The Regents Of The University Of California Reducing Nephropathy with Inhibitors of Soluble Epoxide Hydrolase and Epoxyeicosanoids
WO2006045119A2 (en) 2004-10-20 2006-04-27 The Regents Of The University Of California Improved inhibitors for the soluble epoxide hydrolase
UA89514C2 (uk) 2004-12-30 2010-02-10 Janssen Pharmaceutica Nv Похідні феніламідів 4-(бензил)-піперазин-1-карбонових кислот та споріднені сполуки як модулятори гідролази амідів жирних кислот для лікування тривоги, болю та інших станів
WO2007016496A2 (en) 2005-08-02 2007-02-08 Neurogen Corporation Dipiperazinyl ketones and related analogues
AR059826A1 (es) * 2006-03-13 2008-04-30 Univ California Inhibidores de urea conformacionalmente restringidos de epoxido hidrolasa soluble
CN101784529A (zh) * 2007-06-22 2010-07-21 弗·哈夫曼-拉罗切有限公司 作为非核苷逆转录酶抑制剂的脲和氨基甲酸酯衍生物
PL2221298T3 (pl) 2007-11-13 2014-05-30 Taisho Pharmaceutical Co Ltd Pochodne fenylopirazolu
US8461159B2 (en) 2008-11-25 2013-06-11 Jannsen Pharmaceutica BV Heteroaryl-substituted urea modulators of fatty acid amide hydrolase
WO2010068452A1 (en) * 2008-11-25 2010-06-17 Janssen Pharmaceutica Nv Heteroaryl-substituted urea modulators of fatty acid amide hydrolase
TW201039822A (en) 2009-02-06 2010-11-16 Taisho Pharmaceutical Co Ltd Dihydroquinolinone derivatives
BR112012013431B1 (pt) 2009-12-04 2022-04-12 Sunovion Pharmaceuticals, Inc. Composto e seu uso, composição farmacêutica
WO2012054093A2 (en) 2010-01-29 2012-04-26 The Regents Of The University Of California Acyl piperidine inhibitors of soluble epoxide hydrolase
UA108233C2 (uk) 2010-05-03 2015-04-10 Модулятори активності гідролази амідів жирних кислот
CA2801074A1 (en) 2010-06-04 2011-12-08 Albany Molecular Research, Inc. Glycine transporter-1 inhibitors, methods of making them, and uses thereof
WO2012113103A1 (en) * 2011-02-25 2012-08-30 Helsinn Healthcare S.A. Asymmetric ureas and medical uses thereof
TW201321353A (zh) 2011-10-08 2013-06-01 Novartis Ag 胺基甲酸酯／尿素衍生物
KR20140100483A (ko) 2011-12-08 2014-08-14 다이쇼 세이야꾸 가부시끼가이샤 페닐피롤 유도체
WO2013100054A1 (ja) 2011-12-27 2013-07-04 大正製薬株式会社 フェニルトリアゾール誘導体
US9034874B2 (en) 2012-07-20 2015-05-19 Novartis Ag Carbamate/urea derivatives
TWI703130B (zh) * 2014-03-07 2020-09-01 瑞士商赫爾辛保健股份有限公司 對位取代的不對稱脲及其醫療用途
AR100530A1 (es) * 2014-05-19 2016-10-12 Merial Inc Compuestos antihelmínticos
US10752587B2 (en) 2015-12-01 2020-08-25 Merck Sharp & Dohme Corp. Homobispiperidinyl derivatives as liver X receptor beta agonists, compositions and their use
EA037040B1 (ru) 2016-03-22 2021-01-29 Хелсинн Хелскеа Са Асимметричные бензолсульфонилмочевины и их применение в качестве модуляторов рецептора грелина
AU2017275657B2 (en) 2016-06-02 2021-08-19 Novartis Ag Potassium channel modulators
JP2019523279A (ja) 2016-07-29 2019-08-22 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． 化合物および組成物ならびにそれらの使用
IL264446B1 (en) 2016-07-29 2024-05-01 Pgi Drug Discovery Llc Compounds and compositions and their use
PL3571193T3 (pl) 2017-01-23 2022-04-25 Cadent Therapeutics, Inc. Modulatory kanału potasowego
JP7146782B2 (ja) 2017-02-16 2022-10-04 サノビオン ファーマシューティカルズ インク 統合失調症を処置する方法
CN111183138A (zh) 2017-08-02 2020-05-19 赛诺维信制药公司 异色满化合物以及用途
WO2019161238A1 (en) 2018-02-16 2019-08-22 Sunovion Pharmaceuticals Inc. Salts, crystal forms, and production methods thereof
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CN111349609A (zh) * 2018-12-21 2020-06-30 泰州医药城国科化物生物医药科技有限公司 一种无标记组胺受体h3的细胞筛选模型
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ES2819309B2 (es) * 2019-10-14 2021-11-17 Fundacion Para La Investigacion Biomedica Del Hospital Univ De La Princesa Compuestos agonistas nicotínicos y antioxidantes para el tratamiento de enfermedades neurodegenerativas
EP4135690A1 (en) 2020-04-14 2023-02-22 Sunovion Pharmaceuticals Inc. (s)-(4,5-dihydro-7h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine for treating neurological and psychiatric disorders
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DE19614204A1 (de) * 1996-04-10 1997-10-16 Thomae Gmbh Dr K Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
US6673829B2 (en) * 2001-09-14 2004-01-06 Novo Nordisk A/S Aminoazetidine,-pyrrolidine and -piperidine derivatives
DE60234616D1 (de) * 2001-09-14 2010-01-14 High Point Pharmaceuticals Llc Substituierte piperidinen mit selektiver bindungsfähigkeit zu histamin h3-rezeptoren
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EP1554260A1 (en) * 2002-10-22 2005-07-20 Glaxo Group Limited Aryloxyalkylamine derivatives as h3 receptor ligands
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CN1902177A (zh) * 2003-09-22 2007-01-24 万有制药株式会社 新哌啶衍生物

Also Published As

Publication number Publication date
WO2006014136A1 (en) 2006-02-09
IL180548A0 (en) 2007-06-03
CN1993325A (zh) 2007-07-04
US20080064706A1 (en) 2008-03-13
AU2005267932A1 (en) 2006-02-09
EP1781613A1 (en) 2007-05-09
CA2576112A1 (en) 2006-02-09
KR20070043998A (ko) 2007-04-26
ZA200700683B (en) 2008-08-27
RU2007105970A (ru) 2008-09-10
JP2008508353A (ja) 2008-03-21
BRPI0514035A (pt) 2008-05-27
MX2007001226A (es) 2007-03-23

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