SE0202465D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE0202465D0
SE0202465D0 SE0202465A SE0202465A SE0202465D0 SE 0202465 D0 SE0202465 D0 SE 0202465D0 SE 0202465 A SE0202465 A SE 0202465A SE 0202465 A SE0202465 A SE 0202465A SE 0202465 D0 SE0202465 D0 SE 0202465D0
Authority
SE
Sweden
Prior art keywords
new compounds
formula
receptor agonists
acetylcholine receptor
nicotinic acetylcholine
Prior art date
Application number
SE0202465A
Other languages
English (en)
Swedish (sv)
Inventor
Eifion Phillips
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0202465A priority Critical patent/SE0202465D0/xx
Publication of SE0202465D0 publication Critical patent/SE0202465D0/xx
Priority to AT03788213T priority patent/ATE430152T1/de
Priority to CNB038192578A priority patent/CN100436453C/zh
Priority to BR0313233-1A priority patent/BR0313233A/pt
Priority to CA002493246A priority patent/CA2493246A1/en
Priority to US10/524,482 priority patent/US20060052368A1/en
Priority to MXPA05001584A priority patent/MXPA05001584A/es
Priority to PCT/SE2003/001276 priority patent/WO2004016616A1/en
Priority to DE60327441T priority patent/DE60327441D1/de
Priority to AU2003248590A priority patent/AU2003248590B2/en
Priority to JP2004529001A priority patent/JP2005539030A/ja
Priority to KR1020057002266A priority patent/KR20060005334A/ko
Priority to EP03788213A priority patent/EP1539764B1/en
Priority to IL16642505A priority patent/IL166425A0/xx
Priority to ZA200501227A priority patent/ZA200501227B/en
Priority to NO20051260A priority patent/NO20051260L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE0202465A 2002-08-14 2002-08-14 New compounds SE0202465D0 (sv)

Priority Applications (16)

Application Number Priority Date Filing Date Title
SE0202465A SE0202465D0 (sv) 2002-08-14 2002-08-14 New compounds
EP03788213A EP1539764B1 (en) 2002-08-14 2003-08-13 Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists.
MXPA05001584A MXPA05001584A (es) 2002-08-14 2003-08-13 Diazabiciloalcanos sustituidos con arilo como agonistas de acetilcolina nicotinicos.
DE60327441T DE60327441D1 (de) 2002-08-14 2003-08-13 Aryl-substituierte diazabicycloalkane als nikotinische acetylcholinagonisten
BR0313233-1A BR0313233A (pt) 2002-08-14 2003-08-13 Composto, uso do mesmo, método de tratamento ou profilaxia de doenças, e, composição farmacêutica
CA002493246A CA2493246A1 (en) 2002-08-14 2003-08-13 Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists
US10/524,482 US20060052368A1 (en) 2002-08-14 2003-08-13 Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists
AT03788213T ATE430152T1 (de) 2002-08-14 2003-08-13 Aryl-substituierte diazabicycloalkane als nikotinische acetylcholinagonisten
PCT/SE2003/001276 WO2004016616A1 (en) 2002-08-14 2003-08-13 Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists.
CNB038192578A CN100436453C (zh) 2002-08-14 2003-08-13 作为烟碱性乙酰胆碱激动剂的芳基取代的二氮杂双环烷烃
AU2003248590A AU2003248590B2 (en) 2002-08-14 2003-08-13 Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists
JP2004529001A JP2005539030A (ja) 2002-08-14 2003-08-13 ニコチン性アセチルコリン作用剤としてのアリール置換ジアザビシクロアルカン
KR1020057002266A KR20060005334A (ko) 2002-08-14 2003-08-13 니코틴성 아세틸콜린 아고니스트로서의 아릴 치환된디아자비시클로알칸
IL16642505A IL166425A0 (en) 2002-08-14 2005-01-20 Aryl-substituted diazabicyclkanes as nicotinic acetylcholine agonists
ZA200501227A ZA200501227B (en) 2002-08-14 2005-02-10 Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists
NO20051260A NO20051260L (no) 2002-08-14 2005-03-11 Arylsubstituerte diazabicykloalkaner som nikotinacetylcholinagonister

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0202465A SE0202465D0 (sv) 2002-08-14 2002-08-14 New compounds

Publications (1)

Publication Number Publication Date
SE0202465D0 true SE0202465D0 (sv) 2002-08-14

Family

ID=20288753

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0202465A SE0202465D0 (sv) 2002-08-14 2002-08-14 New compounds

Country Status (16)

Country Link
US (1) US20060052368A1 (enExample)
EP (1) EP1539764B1 (enExample)
JP (1) JP2005539030A (enExample)
KR (1) KR20060005334A (enExample)
CN (1) CN100436453C (enExample)
AT (1) ATE430152T1 (enExample)
AU (1) AU2003248590B2 (enExample)
BR (1) BR0313233A (enExample)
CA (1) CA2493246A1 (enExample)
DE (1) DE60327441D1 (enExample)
IL (1) IL166425A0 (enExample)
MX (1) MXPA05001584A (enExample)
NO (1) NO20051260L (enExample)
SE (1) SE0202465D0 (enExample)
WO (1) WO2004016616A1 (enExample)
ZA (1) ZA200501227B (enExample)

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DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
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US7932248B2 (en) 2005-11-09 2011-04-26 Memory Pharmaceuticals Corporation 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
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JP5694645B2 (ja) 2006-03-16 2015-04-01 ニコノヴァム エービーＮｉｃｏｎｏｖｕｍ Ａｂ 改善された嗅ぎたばこ組成物
TWI454262B (zh) * 2006-11-02 2014-10-01 Targacept Inc 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺
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JP5749797B2 (ja) 2010-05-17 2015-07-15 フォルム ファーマシューティカルズ、インコーポレイテッド （ｒ）−７−クロロ−ｎ−（キヌクリジン−３−イル）ベンゾ［ｂ］チオフェン−２−カルボキサミド塩酸塩一水和物の結晶形
CN103270039B (zh) * 2010-12-22 2016-03-30 东曹株式会社 环状胺化合物及使用该环状胺化合物制造聚氨酯树脂的方法
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WO2019005874A1 (en) 2017-06-26 2019-01-03 The Trustees Of Columbia University In The City Of New York CHOLINERGIC AGONISM FOR THE TREATMENT OF PANCREATIC CANCER
JP2021138648A (ja) 2020-03-04 2021-09-16 武田薬品工業株式会社 経口固形製剤

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Also Published As

Publication number Publication date
CN100436453C (zh) 2008-11-26
ATE430152T1 (de) 2009-05-15
EP1539764A1 (en) 2005-06-15
AU2003248590A1 (en) 2004-03-03
EP1539764B1 (en) 2009-04-29
CA2493246A1 (en) 2004-02-26
CN1675215A (zh) 2005-09-28
BR0313233A (pt) 2005-06-14
WO2004016616A1 (en) 2004-02-26
US20060052368A1 (en) 2006-03-09
DE60327441D1 (de) 2009-06-10
MXPA05001584A (es) 2005-04-25
NO20051260L (no) 2005-05-10
ZA200501227B (en) 2006-07-26
AU2003248590B2 (en) 2008-03-20
JP2005539030A (ja) 2005-12-22
KR20060005334A (ko) 2006-01-17
IL166425A0 (en) 2006-01-15

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