SE0202110D0 - Iscom preparation and use thereof - Google Patents
Iscom preparation and use thereofInfo
- Publication number
- SE0202110D0 SE0202110D0 SE0202110A SE0202110A SE0202110D0 SE 0202110 D0 SE0202110 D0 SE 0202110D0 SE 0202110 A SE0202110 A SE 0202110A SE 0202110 A SE0202110 A SE 0202110A SE 0202110 D0 SE0202110 D0 SE 0202110D0
- Authority
- SE
- Sweden
- Prior art keywords
- iscom
- complexes
- complex
- mixture
- parts
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0202110A SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Iscom preparation and use thereof |
BRPI0312472A BRPI0312472B8 (pt) | 2002-07-05 | 2003-07-07 | composição compreendendo dois complexos iscom diferentes |
PCT/SE2003/001180 WO2004004762A1 (en) | 2002-07-05 | 2003-07-07 | Iscom preparation and use thereof |
ES03738849T ES2328474T3 (es) | 2002-07-05 | 2003-07-07 | Preparacion de iscom y su utilizacion. |
JP2004519469A JP4636877B2 (ja) | 2002-07-05 | 2003-07-07 | 免疫刺激複合体の調製及びその使用 |
NZ537661A NZ537661A (en) | 2002-07-05 | 2003-07-07 | Iscom preparation and use thereof |
CA2491457A CA2491457C (en) | 2002-07-05 | 2003-07-07 | Iscom preparation and use thereof |
EP03738849A EP1539231B1 (en) | 2002-07-05 | 2003-07-07 | Iscom preparation and use thereof |
US10/520,022 US20060121065A1 (en) | 2002-07-05 | 2003-07-07 | Iscom preparation and use thereof |
DK03738849T DK1539231T3 (da) | 2002-07-05 | 2003-07-07 | Iscom-præparation og anvendelse deraf |
AU2003245220A AU2003245220B2 (en) | 2002-07-05 | 2003-07-07 | Iscom preparation and use thereof |
AT03738849T ATE434443T1 (de) | 2002-07-05 | 2003-07-07 | Iscom-zubereitung und ihre verwendung |
DE60328108T DE60328108D1 (de) | 2002-07-05 | 2003-07-07 | Iscom-zubereitung und ihre verwendung |
ZA200500073A ZA200500073B (en) | 2002-07-05 | 2005-01-04 | Iscom preparation and use thereof. |
US14/587,116 US10729764B2 (en) | 2002-07-05 | 2014-12-31 | ISCOM preparation and use thereof |
US16/823,836 US20200215189A1 (en) | 2002-07-05 | 2020-03-19 | Iscom preparation and use thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0202110A SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Iscom preparation and use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0202110D0 true SE0202110D0 (sv) | 2002-07-05 |
Family
ID=20288449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0202110A SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Iscom preparation and use thereof |
Country Status (14)
Country | Link |
---|---|
US (3) | US20060121065A1 (xx) |
EP (1) | EP1539231B1 (xx) |
JP (1) | JP4636877B2 (xx) |
AT (1) | ATE434443T1 (xx) |
AU (1) | AU2003245220B2 (xx) |
BR (1) | BRPI0312472B8 (xx) |
CA (1) | CA2491457C (xx) |
DE (1) | DE60328108D1 (xx) |
DK (1) | DK1539231T3 (xx) |
ES (1) | ES2328474T3 (xx) |
NZ (1) | NZ537661A (xx) |
SE (1) | SE0202110D0 (xx) |
WO (1) | WO2004004762A1 (xx) |
ZA (1) | ZA200500073B (xx) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
SE0301998D0 (sv) * | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
PL1838341T3 (pl) | 2005-01-20 | 2014-04-30 | Isconova Ab | Kompozycja szczepionki obejmująca białko wiążące fibronektynę lub peptyd wiążący fibronektynę |
EP1764369A1 (de) * | 2005-09-16 | 2007-03-21 | Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH | Vakzine enthaltend trunkiertes HBV core protein plus Saponin-basierendes Adjuvants |
EP2004226A1 (en) | 2006-03-24 | 2008-12-24 | Novartis Vaccines and Diagnostics GmbH & Co. KG | Storage of influenza vaccines without refrigeration |
US20110206692A1 (en) | 2006-06-09 | 2011-08-25 | Novartis Ag | Conformers of bacterial adhesins |
EP1902727A1 (de) * | 2006-09-22 | 2008-03-26 | Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH | Vakzine enthaltend trunkiertes HBV core protein plus Saponin-basierendes Adjuvants |
WO2008031878A1 (en) * | 2006-09-15 | 2008-03-20 | Rhein Biotech Gesellschaft für neue Biotechnologische Prozesse und Produkte mbH | A composition for therapy and/or for prophylaxis of hbv-infections and hbv-mediated diseases |
EA201070066A1 (ru) | 2007-06-27 | 2010-06-30 | Новартис Аг | Вакцины против гриппа с низким содержанием добавок |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
WO2012011868A1 (en) * | 2010-07-23 | 2012-01-26 | Osterhaus A D M E | Influenza vaccine |
US8771709B2 (en) | 2010-09-20 | 2014-07-08 | Crucell Holland B.V. | Therapeutic vaccination against active Tuberculosis |
ES2673957T5 (es) | 2011-10-03 | 2021-12-15 | Croda Int Plc | Nanopartículas, procedimiento para la preparación y utilización de las mismas como portadoras de moléculas anfipáticas o hidrofóbicas en el campo de la medicina, incluyendo el tratamiento del cáncer, y compuestos de tipo alimentario |
MX357009B (es) | 2011-11-28 | 2018-06-22 | Crucell Holland Bv | Vacunas contra el virus de la influenza y sus usos. |
US8932607B2 (en) | 2012-03-12 | 2015-01-13 | Crucell Holland B.V. | Batches of recombinant adenovirus with altered terminal ends |
CN104379733B (zh) | 2012-03-12 | 2016-01-20 | 克鲁塞尔荷兰公司 | 具改变末端的重组腺病毒群 |
US9125870B2 (en) | 2012-03-22 | 2015-09-08 | Crucell Holland B.V. | Vaccine against RSV |
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CA2900008A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
DK2863943T3 (en) | 2013-03-08 | 2016-11-07 | Janssen Vaccines & Prevention Bv | acellular pertussis vaccines |
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Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8205892D0 (sv) * | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
SE8405493D0 (sv) * | 1984-11-01 | 1984-11-01 | Bror Morein | Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel |
DK166762B1 (da) * | 1986-01-14 | 1993-07-12 | Nederlanden Staat | Fremgangsmaade til fremstilling af immunogenkomplekser og farmaceutisk sammensaetning indeholdende saadanne komplekser |
US5583112A (en) * | 1987-05-29 | 1996-12-10 | Cambridge Biotech Corporation | Saponin-antigen conjugates and the use thereof |
US5057540A (en) * | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
CA1331443C (en) * | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
NZ230747A (en) * | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
NL9002314A (nl) * | 1990-10-23 | 1992-05-18 | Nederlanden Staat | Immunogene complexen, in het bijzonder iscoms. |
AUPM873294A0 (en) * | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
SE9600647D0 (sv) | 1996-02-21 | 1996-02-21 | Bror Morein | Ny användning |
US6231859B1 (en) * | 1996-12-02 | 2001-05-15 | Aquila Biopharmaceuticals, Inc. | Saponin adjuvant compositions |
AUPO517897A0 (en) * | 1997-02-19 | 1997-04-11 | Csl Limited | Chelating immunostimulating complexes |
US6558670B1 (en) * | 1999-04-19 | 2003-05-06 | Smithkline Beechman Biologicals S.A. | Vaccine adjuvants |
SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
-
2002
- 2002-07-05 SE SE0202110A patent/SE0202110D0/xx unknown
-
2003
- 2003-07-07 ES ES03738849T patent/ES2328474T3/es not_active Expired - Lifetime
- 2003-07-07 BR BRPI0312472A patent/BRPI0312472B8/pt active IP Right Grant
- 2003-07-07 JP JP2004519469A patent/JP4636877B2/ja not_active Expired - Lifetime
- 2003-07-07 AT AT03738849T patent/ATE434443T1/de active
- 2003-07-07 EP EP03738849A patent/EP1539231B1/en not_active Expired - Lifetime
- 2003-07-07 US US10/520,022 patent/US20060121065A1/en not_active Abandoned
- 2003-07-07 WO PCT/SE2003/001180 patent/WO2004004762A1/en active Application Filing
- 2003-07-07 NZ NZ537661A patent/NZ537661A/en not_active IP Right Cessation
- 2003-07-07 DK DK03738849T patent/DK1539231T3/da active
- 2003-07-07 CA CA2491457A patent/CA2491457C/en not_active Expired - Lifetime
- 2003-07-07 DE DE60328108T patent/DE60328108D1/de not_active Expired - Lifetime
- 2003-07-07 AU AU2003245220A patent/AU2003245220B2/en not_active Expired
-
2005
- 2005-01-04 ZA ZA200500073A patent/ZA200500073B/xx unknown
-
2014
- 2014-12-31 US US14/587,116 patent/US10729764B2/en active Active
-
2020
- 2020-03-19 US US16/823,836 patent/US20200215189A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20150209425A1 (en) | 2015-07-30 |
BR0312472A (pt) | 2005-04-26 |
JP2006511451A (ja) | 2006-04-06 |
ES2328474T3 (es) | 2009-11-13 |
AU2003245220B2 (en) | 2009-04-23 |
US10729764B2 (en) | 2020-08-04 |
BRPI0312472B8 (pt) | 2021-05-25 |
US20200215189A1 (en) | 2020-07-09 |
BRPI0312472B1 (pt) | 2019-07-16 |
NZ537661A (en) | 2008-08-29 |
EP1539231A1 (en) | 2005-06-15 |
US20060121065A1 (en) | 2006-06-08 |
EP1539231B1 (en) | 2009-06-24 |
CA2491457C (en) | 2012-09-04 |
AU2003245220A1 (en) | 2004-01-23 |
ZA200500073B (en) | 2006-02-22 |
DE60328108D1 (de) | 2009-08-06 |
DK1539231T3 (da) | 2009-09-14 |
ATE434443T1 (de) | 2009-07-15 |
CA2491457A1 (en) | 2004-01-15 |
JP4636877B2 (ja) | 2011-02-23 |
WO2004004762A1 (en) | 2004-01-15 |
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