SA518400392B1 - صيغ ثابتة لمضاد حيوي من ببتيد سكري - Google Patents
صيغ ثابتة لمضاد حيوي من ببتيد سكريInfo
- Publication number
- SA518400392B1 SA518400392B1 SA518400392A SA518400392A SA518400392B1 SA 518400392 B1 SA518400392 B1 SA 518400392B1 SA 518400392 A SA518400392 A SA 518400392A SA 518400392 A SA518400392 A SA 518400392A SA 518400392 B1 SA518400392 B1 SA 518400392B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- glycopeptide antibiotic
- antibiotic formulations
- formulations
- stabilized glycopeptide
- stabilized
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662333357P | 2016-05-09 | 2016-05-09 | |
| PCT/EP2017/060653 WO2017194385A1 (en) | 2016-05-09 | 2017-05-04 | Stabilized glycopeptide antibiotic formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SA518400392B1 true SA518400392B1 (ar) | 2022-05-09 |
Family
ID=58745200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SA518400392A SA518400392B1 (ar) | 2016-05-09 | 2018-11-07 | صيغ ثابتة لمضاد حيوي من ببتيد سكري |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US10729708B2 (enExample) |
| EP (1) | EP3454883A1 (enExample) |
| JP (1) | JP6946343B2 (enExample) |
| KR (1) | KR20190005940A (enExample) |
| CN (1) | CN109069580A (enExample) |
| AR (1) | AR109454A1 (enExample) |
| AU (1) | AU2017262943B2 (enExample) |
| BR (1) | BR112018072948A2 (enExample) |
| CL (1) | CL2018003147A1 (enExample) |
| CO (1) | CO2018011701A2 (enExample) |
| EA (1) | EA201892413A1 (enExample) |
| IL (1) | IL262796A (enExample) |
| JO (2) | JOP20170111B1 (enExample) |
| MX (1) | MX388732B (enExample) |
| SA (1) | SA518400392B1 (enExample) |
| SG (1) | SG11201809908TA (enExample) |
| TW (2) | TWI769694B (enExample) |
| UY (1) | UY37233A (enExample) |
| WO (1) | WO2017194385A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016071495A1 (en) | 2014-11-06 | 2016-05-12 | Xellia Pharmaceuticals Aps | Glycopeptide compositions |
| WO2021231361A1 (en) * | 2020-05-11 | 2021-11-18 | Anovent Pharmaceutical (U.S.), Llc | Pharmaceutical formulation containing active metabolites of remdesivir for inhalation |
| WO2022031830A1 (en) * | 2020-08-04 | 2022-02-10 | Harrow Ip Llc | Antibacterial compositions and methods for fabricating thereof |
| EP4014965A1 (en) | 2020-12-16 | 2022-06-22 | EVER Valinject GmbH | Aqueous solution |
| EP4014969A1 (en) | 2020-12-16 | 2022-06-22 | EVER Valinject GmbH | Aqueous solution |
| CN115804832B (zh) * | 2021-09-14 | 2026-06-16 | 海南普利制药股份有限公司 | 一种万古霉素水溶液组合物 |
| JPWO2023171588A1 (enExample) * | 2022-03-08 | 2023-09-14 | ||
| US20250295727A1 (en) * | 2022-04-26 | 2025-09-25 | Hikma Pharmaceuticals Usa Inc. | Stable, ready-to-administer aqueous formulations of dalbavancin |
| GB202207344D0 (en) | 2022-05-19 | 2022-07-06 | Arecor Ltd | Novel composition |
| GB202207345D0 (en) | 2022-05-19 | 2022-07-06 | Arecor Ltd | Novel composition |
| CN117618338A (zh) * | 2022-08-16 | 2024-03-01 | 海南普利制药股份有限公司 | 一种稳定的奥利万星药物水溶液及其制备方法 |
| AU2023359653A1 (en) * | 2022-10-12 | 2025-05-29 | Hikma Pharmaceuticals Usa Inc. | Liquid dalbavancin composition |
| UY40482A (es) * | 2022-10-12 | 2024-04-30 | Hikma Pharmaceuticals Usa Inc | Composición líquida de dalbavancina. |
| EP4431083A1 (en) * | 2023-03-16 | 2024-09-18 | Adalvo Limited | Formulation of dalbavancin |
| WO2025158262A1 (en) * | 2024-01-23 | 2025-07-31 | Lupin Limited | Stable pharmaceutical compositions of dalbavancin as ready-to-dilute formulation |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1278549A (en) * | 1916-12-16 | 1918-09-10 | J E Simmons | Nut and bolt lock. |
| US4670258A (en) | 1984-02-10 | 1987-06-02 | Vanderbilt University | Storable prepackaged aqueous solutions of vancomycin |
| US4885275A (en) | 1987-10-15 | 1989-12-05 | Eli Lilly And Company | Vancomycin-HCL solutions and the lyophilization thereof |
| WO1997019690A1 (en) * | 1995-12-01 | 1997-06-05 | Eli Lilly And Company | Stable vancomycin hydrochloride solutions |
| JPH1180021A (ja) | 1997-09-02 | 1999-03-23 | Kayaku:Kk | バンコマイシン注射剤 |
| EP1276759B1 (en) * | 2000-05-02 | 2008-07-30 | Theravance, Inc. | Reductive alkylation process on glycopeptides |
| DE60136926D1 (de) * | 2000-05-02 | 2009-01-22 | Theravance Inc | Zusammensetzung die eine zyklodextrin und ein glykopeptid-antibiotikum enthält |
| WO2001083520A2 (en) * | 2000-05-02 | 2001-11-08 | Theravance,Inc | Polyacid glycopeptide derivatives |
| AU2001267011B2 (en) * | 2000-06-21 | 2006-02-02 | Cubist Pharmaceuticals, Inc. | Compositions and methods to improve the oral absorption of antimicrobial agents |
| UA75083C2 (uk) | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
| US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
| US7119061B2 (en) * | 2002-11-18 | 2006-10-10 | Vicuron Pharmaceuticals, Inc. | Dalbavancin compositions for treatment of bacterial infections |
| WO2005042584A2 (en) * | 2003-10-31 | 2005-05-12 | The University Of Kansas | Sulfoalkyl ether-alkyl ether cyclodextrin derivatives |
| EP1848413B1 (en) | 2005-02-14 | 2014-04-09 | Venus Remedies Limited | Parenteral combination therapy for infective conditions with drug resistant bacterium |
| CN1857716A (zh) * | 2006-03-14 | 2006-11-08 | 浙江大学 | 注射用盐酸万古霉素及其制备方法 |
| JP2008201778A (ja) | 2007-01-25 | 2008-09-04 | Mochida Pharmaceut Co Ltd | バンコマイシン液状製剤 |
| US8518873B2 (en) | 2007-09-12 | 2013-08-27 | The Medicines Company | Method of inhibiting clostridium difficile by administration of oritavancin |
| US7635773B2 (en) * | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| CN102755629A (zh) * | 2012-08-02 | 2012-10-31 | 上海瑞创医药科技有限公司 | 与万古霉素形成抗菌增效包合物的组分和制备方法及其应用 |
| CA2891487A1 (en) * | 2012-11-29 | 2014-06-05 | Insmed Incorporated | Stabilized vancomycin formulations |
| CN104043104B (zh) | 2013-03-15 | 2018-07-10 | 浙江创新生物有限公司 | 含盐酸万古霉素的喷雾干粉及其工业化制备方法 |
| US9616098B2 (en) | 2013-05-30 | 2017-04-11 | Scidose, Llc | Formulations of vancomycin |
| WO2016071495A1 (en) * | 2014-11-06 | 2016-05-12 | Xellia Pharmaceuticals Aps | Glycopeptide compositions |
| EA036750B1 (ru) | 2016-01-08 | 2020-12-16 | Гуфик Байосайенсиз Лимитед | Лиофилизированная парентеральная композиция тигециклина и способ ее приготовления |
| CA3014294A1 (en) * | 2016-02-18 | 2017-08-24 | Melinta Therapeutics, Inc. | Oritavancin formulations |
-
2017
- 2017-05-04 MX MX2018013584A patent/MX388732B/es unknown
- 2017-05-04 EP EP17724773.1A patent/EP3454883A1/en not_active Withdrawn
- 2017-05-04 AU AU2017262943A patent/AU2017262943B2/en not_active Ceased
- 2017-05-04 JP JP2018558750A patent/JP6946343B2/ja active Active
- 2017-05-04 BR BR112018072948-5A patent/BR112018072948A2/pt not_active IP Right Cessation
- 2017-05-04 SG SG11201809908TA patent/SG11201809908TA/en unknown
- 2017-05-04 CN CN201780027315.7A patent/CN109069580A/zh active Pending
- 2017-05-04 WO PCT/EP2017/060653 patent/WO2017194385A1/en not_active Ceased
- 2017-05-04 KR KR1020187035449A patent/KR20190005940A/ko not_active Ceased
- 2017-05-04 US US16/300,137 patent/US10729708B2/en active Active
- 2017-05-04 EA EA201892413A patent/EA201892413A1/ru unknown
- 2017-05-07 JO JOJO/P/2017/0111A patent/JOP20170111B1/ar active
- 2017-05-08 AR ARP170101197A patent/AR109454A1/es unknown
- 2017-05-08 UY UY0001037233A patent/UY37233A/es active IP Right Grant
- 2017-05-09 TW TW110104598A patent/TWI769694B/zh active
- 2017-05-09 TW TW106115255A patent/TWI772296B/zh active
-
2018
- 2018-10-29 CO CONC2018/0011701A patent/CO2018011701A2/es unknown
- 2018-11-05 IL IL262796A patent/IL262796A/en unknown
- 2018-11-06 CL CL2018003147A patent/CL2018003147A1/es unknown
- 2018-11-07 SA SA518400392A patent/SA518400392B1/ar unknown
-
2022
- 2022-02-17 JO JOP/2022/0039A patent/JOP20220039A1/ar unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JOP20220039A1 (ar) | 2023-01-30 |
| CN109069580A (zh) | 2018-12-21 |
| MX388732B (es) | 2025-03-20 |
| EP3454883A1 (en) | 2019-03-20 |
| CO2018011701A2 (es) | 2019-02-08 |
| KR20190005940A (ko) | 2019-01-16 |
| TW201740955A (zh) | 2017-12-01 |
| MX2018013584A (es) | 2019-04-01 |
| SG11201809908TA (en) | 2018-12-28 |
| WO2017194385A1 (en) | 2017-11-16 |
| IL262796A (en) | 2018-12-31 |
| US10729708B2 (en) | 2020-08-04 |
| AU2017262943A1 (en) | 2018-11-22 |
| TW202133875A (zh) | 2021-09-16 |
| JP2019518733A (ja) | 2019-07-04 |
| TWI769694B (zh) | 2022-07-01 |
| AU2017262943B2 (en) | 2020-05-14 |
| CA3021935A1 (en) | 2017-11-16 |
| UY37233A (es) | 2018-01-02 |
| JP6946343B2 (ja) | 2021-10-06 |
| BR112018072948A2 (pt) | 2019-02-19 |
| CL2018003147A1 (es) | 2018-12-28 |
| US20190175632A1 (en) | 2019-06-13 |
| AR109454A1 (es) | 2018-12-12 |
| EA201892413A1 (ru) | 2019-05-31 |
| JOP20170111B1 (ar) | 2022-03-15 |
| TWI772296B (zh) | 2022-08-01 |
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