SA518400392B1 - صيغ ثابتة لمضاد حيوي من ببتيد سكري - Google Patents
صيغ ثابتة لمضاد حيوي من ببتيد سكريInfo
- Publication number
- SA518400392B1 SA518400392B1 SA518400392A SA518400392A SA518400392B1 SA 518400392 B1 SA518400392 B1 SA 518400392B1 SA 518400392 A SA518400392 A SA 518400392A SA 518400392 A SA518400392 A SA 518400392A SA 518400392 B1 SA518400392 B1 SA 518400392B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- glycopeptide antibiotic
- antibiotic formulations
- formulations
- stabilized glycopeptide
- stabilized
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
يتعلق الاختراع الحالي بالكشف عن صيغ سائلة لمضادات حيوية antibiotics من ببتيد سكري glycopeptide أو أملاح منها مقبولة صيدلانيا، حيث يتم اختيار مضاد حيوي من ببتيد سكري من فانكوميسين Vancomycin، تيلافانسين Telavancin، أوريتافانسين Oritavancin، تيكوبلانين Teicoplanin ودالبافانسين Dalbavancin. تكون الصيغ المذكورة مناسبة كمحاليل تسريب infusion solutions أو كناتج تركيز لتكوين محاليل تسريب. شكل1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662333357P | 2016-05-09 | 2016-05-09 | |
PCT/EP2017/060653 WO2017194385A1 (en) | 2016-05-09 | 2017-05-04 | Stabilized glycopeptide antibiotic formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
SA518400392B1 true SA518400392B1 (ar) | 2022-05-09 |
Family
ID=58745200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SA518400392A SA518400392B1 (ar) | 2016-05-09 | 2018-11-07 | صيغ ثابتة لمضاد حيوي من ببتيد سكري |
Country Status (20)
Country | Link |
---|---|
US (1) | US10729708B2 (ar) |
EP (1) | EP3454883A1 (ar) |
JP (1) | JP6946343B2 (ar) |
KR (1) | KR20190005940A (ar) |
CN (1) | CN109069580A (ar) |
AR (1) | AR109454A1 (ar) |
AU (1) | AU2017262943B2 (ar) |
BR (1) | BR112018072948A2 (ar) |
CA (1) | CA3021935A1 (ar) |
CL (1) | CL2018003147A1 (ar) |
CO (1) | CO2018011701A2 (ar) |
EA (1) | EA201892413A1 (ar) |
IL (1) | IL262796A (ar) |
JO (2) | JOP20170111B1 (ar) |
MX (1) | MX2018013584A (ar) |
SA (1) | SA518400392B1 (ar) |
SG (1) | SG11201809908TA (ar) |
TW (2) | TWI772296B (ar) |
UY (1) | UY37233A (ar) |
WO (1) | WO2017194385A1 (ar) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102603756B1 (ko) | 2014-11-06 | 2023-11-16 | 셀리아 파마슈티칼즈 에이피에스 | 글리코펩티드 조성물 |
WO2021231361A1 (en) * | 2020-05-11 | 2021-11-18 | Anovent Pharmaceutical (U.S.), Llc | Pharmaceutical formulation containing active metabolites of remdesivir for inhalation |
EP4014965A1 (en) | 2020-12-16 | 2022-06-22 | EVER Valinject GmbH | Aqueous solution |
EP4014969A1 (en) | 2020-12-16 | 2022-06-22 | EVER Valinject GmbH | Aqueous solution |
CN115804832A (zh) * | 2021-09-14 | 2023-03-17 | 海南普利制药股份有限公司 | 一种万古霉素水溶液组合物 |
WO2023171588A1 (ja) * | 2022-03-08 | 2023-09-14 | 国立大学法人大阪大学 | 抗菌薬を含有するplga製剤 |
WO2023211501A1 (en) * | 2022-04-26 | 2023-11-02 | Hikma Pharmaceuticals Usa Inc. | Stable, ready-to-administer aqueous formulations of dalbavancin |
GB202207344D0 (en) | 2022-05-19 | 2022-07-06 | Arecor Ltd | Novel composition |
GB202207345D0 (en) | 2022-05-19 | 2022-07-06 | Arecor Ltd | Novel composition |
CN117618338A (zh) * | 2022-08-16 | 2024-03-01 | 海南普利制药股份有限公司 | 一种稳定的奥利万星药物水溶液及其制备方法 |
US20240139282A1 (en) * | 2022-10-12 | 2024-05-02 | Xellia Pharmaceuticals Aps | Liquid dalbavancin compositions |
WO2024079224A1 (en) * | 2022-10-12 | 2024-04-18 | Xellia Pharmaceuticals Aps | Liquid dalbavancin composition |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1278549A (en) * | 1916-12-16 | 1918-09-10 | J E Simmons | Nut and bolt lock. |
US4670258A (en) | 1984-02-10 | 1987-06-02 | Vanderbilt University | Storable prepackaged aqueous solutions of vancomycin |
US4885275A (en) | 1987-10-15 | 1989-12-05 | Eli Lilly And Company | Vancomycin-HCL solutions and the lyophilization thereof |
AU1407197A (en) | 1995-12-01 | 1997-06-19 | Eli Lilly And Company | Stable vancomycin hydrochloride solutions |
JPH1180021A (ja) | 1997-09-02 | 1999-03-23 | Kayaku:Kk | バンコマイシン注射剤 |
CN1223378C (zh) * | 2000-05-02 | 2005-10-19 | 施万制药 | 含有糖肽抗生素和环糊精的药物组合物 |
US6770621B2 (en) * | 2000-05-02 | 2004-08-03 | Theravance, Inc. | Polyacid glycopeptide derivatives |
CN100532392C (zh) * | 2000-05-02 | 2009-08-26 | 施万制药 | 还原性烷基化方法 |
BR0112393A (pt) * | 2000-06-21 | 2003-07-08 | Internat Health Man Associates | Composições e processos para aperfeiçoamento de absorção oral de agentes antimicrobiais |
UA75083C2 (uk) * | 2000-06-22 | 2006-03-15 | Тераванс, Інк. | Похідні глікопептидфосфонатів |
US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
US7119061B2 (en) * | 2002-11-18 | 2006-10-10 | Vicuron Pharmaceuticals, Inc. | Dalbavancin compositions for treatment of bacterial infections |
KR20060096490A (ko) * | 2003-10-31 | 2006-09-11 | 더 유니버시티 오브 캔사스 | 술포알킬 에테르-알킬 에테르 시클로덱스트린 유도체 |
AU2006213441B2 (en) | 2005-02-14 | 2011-12-01 | Venus Remedies Limited | Parenteral combination therpy for infective conditions with drug resistant bacterium |
CN1857716A (zh) * | 2006-03-14 | 2006-11-08 | 浙江大学 | 注射用盐酸万古霉素及其制备方法 |
JP2008201778A (ja) | 2007-01-25 | 2008-09-04 | Mochida Pharmaceut Co Ltd | バンコマイシン液状製剤 |
JP5591112B2 (ja) | 2007-09-12 | 2014-09-17 | ターガンタ セラピューティクス コーポレイション | オリタバンシンの投与によってクロストリジウム・ディフィシレを抑制する方法 |
US7635773B2 (en) * | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
CN102755629A (zh) * | 2012-08-02 | 2012-10-31 | 上海瑞创医药科技有限公司 | 与万古霉素形成抗菌增效包合物的组分和制备方法及其应用 |
RU2018135921A (ru) | 2012-11-29 | 2019-02-05 | Инсмед Инкорпорейтед | Стабилизированные составы ванкомицина |
CN104043104B (zh) | 2013-03-15 | 2018-07-10 | 浙江创新生物有限公司 | 含盐酸万古霉素的喷雾干粉及其工业化制备方法 |
WO2014194296A1 (en) | 2013-05-30 | 2014-12-04 | Scidose, Llc | Formulations of vancomycin |
KR102603756B1 (ko) * | 2014-11-06 | 2023-11-16 | 셀리아 파마슈티칼즈 에이피에스 | 글리코펩티드 조성물 |
WO2017118994A1 (en) | 2016-01-08 | 2017-07-13 | Gufic Biosciences Limited | A freeze dried parenteral composition of tigecycline and process for preparation thereof |
AU2017221435A1 (en) * | 2016-02-18 | 2018-09-06 | Melinta Therapeutics, Inc. | Oritavancin formulations |
-
2017
- 2017-05-04 CN CN201780027315.7A patent/CN109069580A/zh active Pending
- 2017-05-04 BR BR112018072948-5A patent/BR112018072948A2/pt not_active IP Right Cessation
- 2017-05-04 JP JP2018558750A patent/JP6946343B2/ja active Active
- 2017-05-04 EA EA201892413A patent/EA201892413A1/ru unknown
- 2017-05-04 EP EP17724773.1A patent/EP3454883A1/en not_active Withdrawn
- 2017-05-04 AU AU2017262943A patent/AU2017262943B2/en not_active Ceased
- 2017-05-04 MX MX2018013584A patent/MX2018013584A/es unknown
- 2017-05-04 KR KR1020187035449A patent/KR20190005940A/ko not_active Application Discontinuation
- 2017-05-04 US US16/300,137 patent/US10729708B2/en active Active
- 2017-05-04 SG SG11201809908TA patent/SG11201809908TA/en unknown
- 2017-05-04 CA CA3021935A patent/CA3021935A1/en active Pending
- 2017-05-04 WO PCT/EP2017/060653 patent/WO2017194385A1/en unknown
- 2017-05-07 JO JOP/2017/0111A patent/JOP20170111B1/ar active
- 2017-05-08 UY UY0001037233A patent/UY37233A/es active IP Right Grant
- 2017-05-08 AR ARP170101197A patent/AR109454A1/es unknown
- 2017-05-09 TW TW106115255A patent/TWI772296B/zh active
- 2017-05-09 TW TW110104598A patent/TWI769694B/zh active
-
2018
- 2018-10-29 CO CONC2018/0011701A patent/CO2018011701A2/es unknown
- 2018-11-05 IL IL262796A patent/IL262796A/en unknown
- 2018-11-06 CL CL2018003147A patent/CL2018003147A1/es unknown
- 2018-11-07 SA SA518400392A patent/SA518400392B1/ar unknown
-
2022
- 2022-02-17 JO JOP/2022/0039A patent/JOP20220039A1/ar unknown
Also Published As
Publication number | Publication date |
---|---|
MX2018013584A (es) | 2019-04-01 |
JOP20170111B1 (ar) | 2022-03-14 |
BR112018072948A2 (pt) | 2019-02-19 |
EA201892413A1 (ru) | 2019-05-31 |
TW202133875A (zh) | 2021-09-16 |
WO2017194385A1 (en) | 2017-11-16 |
TW201740955A (zh) | 2017-12-01 |
EP3454883A1 (en) | 2019-03-20 |
AU2017262943A1 (en) | 2018-11-22 |
AR109454A1 (es) | 2018-12-12 |
US10729708B2 (en) | 2020-08-04 |
TWI772296B (zh) | 2022-08-01 |
CN109069580A (zh) | 2018-12-21 |
CA3021935A1 (en) | 2017-11-16 |
US20190175632A1 (en) | 2019-06-13 |
UY37233A (es) | 2018-01-02 |
CL2018003147A1 (es) | 2018-12-28 |
JOP20220039A1 (ar) | 2023-01-30 |
TWI769694B (zh) | 2022-07-01 |
CO2018011701A2 (es) | 2019-02-08 |
KR20190005940A (ko) | 2019-01-16 |
JP2019518733A (ja) | 2019-07-04 |
AU2017262943B2 (en) | 2020-05-14 |
IL262796A (en) | 2018-12-31 |
SG11201809908TA (en) | 2018-12-28 |
JP6946343B2 (ja) | 2021-10-06 |
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