RU99116025A - Новые водные готовые лекарственные формы для получения беспропеллентных аэрозолей - Google Patents
Новые водные готовые лекарственные формы для получения беспропеллентных аэрозолейInfo
- Publication number
- RU99116025A RU99116025A RU99116025/14A RU99116025A RU99116025A RU 99116025 A RU99116025 A RU 99116025A RU 99116025/14 A RU99116025/14 A RU 99116025/14A RU 99116025 A RU99116025 A RU 99116025A RU 99116025 A RU99116025 A RU 99116025A
- Authority
- RU
- Russia
- Prior art keywords
- use according
- complexing agent
- prepellent
- producing
- finished dosage
- Prior art date
Links
- 239000000443 aerosol Substances 0.000 title claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- 239000008139 complexing agent Substances 0.000 claims 4
- 239000002552 dosage form Substances 0.000 claims 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- LSLYOANBFKQKPT-UHFFFAOYSA-N Fenoterol Chemical compound C=1C(O)=CC(O)=CC=1C(O)CNC(C)CC1=CC=C(O)C=C1 LSLYOANBFKQKPT-UHFFFAOYSA-N 0.000 claims 2
- LHLMOSXCXGLMMN-VVQPYUEFSA-M ipratropium bromide Chemical compound [Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N@@+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 LHLMOSXCXGLMMN-VVQPYUEFSA-M 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000011780 sodium chloride Substances 0.000 claims 2
- 229940006211 Anticholinergic mydriatics and cycloplegics Drugs 0.000 claims 1
- 229940065524 Anticholinergics inhalants for obstructive airway diseases Drugs 0.000 claims 1
- 229940098165 Atrovent Drugs 0.000 claims 1
- 229960001361 Ipratropium Bromide Drugs 0.000 claims 1
- LHLMOSXCXGLMMN-WDTICOSOSA-M Ipratropium bromide Chemical compound [Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N+]2(C)C(C)C)C(=O)C(CO)C1=CC=CC=C1 LHLMOSXCXGLMMN-WDTICOSOSA-M 0.000 claims 1
- LCELQERNWLBPSY-KHSTUMNDSA-M Oxitropium bromide Chemical compound [Br-].C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3[N+]([C@H](C2)[C@@H]2[C@H]3O2)(C)CC)=CC=CC=C1 LCELQERNWLBPSY-KHSTUMNDSA-M 0.000 claims 1
- NDAUXUAQIAJITI-UHFFFAOYSA-N Salbutamol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 claims 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Vitamin C Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 1
- 239000000808 adrenergic beta-agonist Substances 0.000 claims 1
- 230000001078 anti-cholinergic Effects 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 239000000043 antiallergic agent Substances 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 229960005070 ascorbic acid Drugs 0.000 claims 1
- 235000010323 ascorbic acid Nutrition 0.000 claims 1
- 239000011668 ascorbic acid Substances 0.000 claims 1
- 230000003454 betamimetic Effects 0.000 claims 1
- 239000000812 cholinergic antagonist Substances 0.000 claims 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N edta Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 1
- 235000019441 ethanol Nutrition 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 229960001022 fenoterol Drugs 0.000 claims 1
- MGFYIUFZLHCRTH-UHFFFAOYSA-N nitrilotriacetic acid Chemical group OC(=O)CN(CC(O)=O)CC(O)=O MGFYIUFZLHCRTH-UHFFFAOYSA-N 0.000 claims 1
- 229960002052 salbutamol Drugs 0.000 claims 1
Claims (8)
1. Применение водных готовых лекарственных форм для получения беспропеллентных аэрозолей для ингаляции, отличающееся тем, что готовая лекарственная форма содержит комплексообразователь.
2. Применение по п.1, отличающееся тем, что активное вещество выбирают из группы бета-миметиков, антихолинергических средств, противоаллергических средств и/ или антигистаминных средств.
3. Применение по п.1 или 2, отличающееся тем, что активное вещество выбирается из группы, включающей фенотерол, ипратропия бромид, беротек, атровент, беродуал, сальбутамол, комбивент, Ba 679 Br, BEA 2108 Br, оксивент.
4. Применение по пп.1 - 3, отличающееся тем, что комплексообразователем является нитрилотриуксусная кислота, лимонная кислота, аскорбиновая кислота или их соли.
5. Применение по пп.1 - 4, отличающееся тем, что комплексообразователем является этилендиаминтетрауксусная кислота или ее соли.
6. Применение по п.5, отличающееся тем, что концентрация комплексообразователя составляет 25 - 75 мг.
7. Применение по одному из пп.1 - 6, отличающееся тем, что готовая лекарственная форма содержит до 70% (об./об.) этилового спирта.
8. Применение по одному из пп.1 - 7, отличающееся тем, что готовая лекарственная форма содержит активное вещество в концентрации 0,001 - 2 г/100 мл раствора.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19653969.2 | 1996-12-20 | ||
| DE19653969A DE19653969A1 (de) | 1996-12-20 | 1996-12-20 | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU99116025A true RU99116025A (ru) | 2001-05-27 |
| RU2219906C2 RU2219906C2 (ru) | 2003-12-27 |
Family
ID=7815979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU99116025/15A RU2219906C2 (ru) | 1996-12-20 | 1997-12-16 | Новые водные готовые лекарственные формы для получения беспропеллентных аэрозолей |
Country Status (39)
| Country | Link |
|---|---|
| US (3) | US20010008632A1 (ru) |
| EP (2) | EP0946146B1 (ru) |
| JP (1) | JP4659160B2 (ru) |
| KR (1) | KR100496723B1 (ru) |
| CN (1) | CN1097455C (ru) |
| AR (1) | AR008721A1 (ru) |
| AT (1) | ATE235887T1 (ru) |
| AU (1) | AU740543B2 (ru) |
| BG (1) | BG64433B1 (ru) |
| BR (1) | BRPI9713596C1 (ru) |
| CA (1) | CA2275392C (ru) |
| CO (1) | CO4920211A1 (ru) |
| DE (2) | DE19653969A1 (ru) |
| DK (1) | DK0946146T3 (ru) |
| EE (1) | EE03949B1 (ru) |
| EG (1) | EG23981A (ru) |
| ES (1) | ES2196388T3 (ru) |
| HK (1) | HK1022846A1 (ru) |
| HR (1) | HRP970694B1 (ru) |
| HU (2) | HU227012B1 (ru) |
| ID (1) | ID22481A (ru) |
| IL (1) | IL130464A (ru) |
| MY (1) | MY124547A (ru) |
| NO (1) | NO320652B1 (ru) |
| NZ (1) | NZ336825A (ru) |
| PE (1) | PE32899A1 (ru) |
| PL (1) | PL189511B1 (ru) |
| PT (1) | PT946146E (ru) |
| RS (1) | RS49803B (ru) |
| RU (1) | RU2219906C2 (ru) |
| SA (1) | SA97180756B1 (ru) |
| SI (1) | SI0946146T1 (ru) |
| SK (1) | SK282910B6 (ru) |
| TR (1) | TR199901408T2 (ru) |
| TW (1) | TW438605B (ru) |
| UA (1) | UA64736C2 (ru) |
| UY (1) | UY24813A1 (ru) |
| WO (1) | WO1998027959A2 (ru) |
| ZA (1) | ZA9711370B (ru) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2510273C2 (ru) * | 2007-12-04 | 2014-03-27 | Пьер Фабр Медикамент | Меквитазин для лечения или предотвращения патологий, в которых задействованы н4 рецепторы гистамина |
Families Citing this family (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19733651A1 (de) * | 1997-08-04 | 1999-02-18 | Boehringer Ingelheim Pharma | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
| DE19808295A1 (de) | 1998-02-27 | 1999-11-11 | Boehringer Ingelheim Int | Behälter für eine medizinische Flüssigkeit |
| DE19847968A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen |
| SE9803770D0 (sv) * | 1998-11-05 | 1998-11-05 | Astra Ab | Dry powder pharmaceutical formulation |
| DE19940713A1 (de) | 1999-02-23 | 2001-03-01 | Boehringer Ingelheim Int | Kartusche für eine Flüssigkeit |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| US20100197719A1 (en) * | 1999-05-12 | 2010-08-05 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
| US20040002548A1 (en) * | 1999-05-12 | 2004-01-01 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
| DE19954516A1 (de) * | 1999-11-12 | 2001-05-17 | Boehringer Ingelheim Int | Epinastin-haltige Lösungen |
| JP2004509920A (ja) * | 2000-09-29 | 2004-04-02 | ボード オブ トラスティーズ オペレーティング ミシガン ステート ユニヴァーシティ | カテコールアミン医薬組成物および方法 |
| US20020137764A1 (en) | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
| WO2002036104A2 (de) * | 2000-10-31 | 2002-05-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalative lösungsformulierung mit einem tiotropiumsalz |
| KR100983208B1 (ko) * | 2000-10-31 | 2010-09-20 | 베링거 잉겔하임 파르마 게엠베하 운트 코 카게 | 티오트로퓸 염을 함유하는 용액의 흡입성 제형 |
| DE10062712A1 (de) * | 2000-12-15 | 2002-06-20 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden |
| US20020193392A1 (en) * | 2000-11-13 | 2002-12-19 | Christel Schmelzer | Pharmaceutical compositions based on tiotropium salts of salts of salmeterol |
| DE10111843A1 (de) * | 2001-03-13 | 2002-09-19 | Boehringer Ingelheim Pharma | Verbindungen zur Behandlung von inflammatorischen Erkrankungen |
| GB2375958B (en) * | 2001-04-09 | 2005-03-02 | George Margetts | The use of steroids to lower the levels of cortisol |
| DE10136555A1 (de) | 2001-07-27 | 2003-02-13 | Boehringer Ingelheim Int | Optimierte Verfahren zur Bestimmung der Aerosol-Partikelgrößenverteilung und Vorrichtung zur Durchführung derartiger Verfahren |
| DE60209511T2 (de) * | 2001-09-18 | 2006-10-05 | Nycomed Danmark Aps | Zusammensetzungen zur behandlung des schnupfens, welche ipratropium und xylometazolin enthalten |
| MXPA04003928A (es) * | 2001-10-26 | 2005-03-31 | Dey L P | Solucion para inhalacion de albuterol, sistema, equipo y metodo para aliviar sintomas de asma pediatrica. |
| AU3297402A (en) * | 2001-10-26 | 2003-10-30 | Dey, L.P. | An albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease |
| JP2010184937A (ja) * | 2001-10-26 | 2010-08-26 | Dey Lp | 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、キット、吸入溶液を中に有する１容器を作成する方法、および、吸入溶液を作成する方法 |
| US7754242B2 (en) * | 2002-03-20 | 2010-07-13 | Alkermes, Inc. | Inhalable sustained therapeutic formulations |
| DE10216036A1 (de) * | 2002-04-11 | 2003-10-23 | Boehringer Ingelheim Pharma | Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz |
| US20040019073A1 (en) * | 2002-04-11 | 2004-01-29 | Boehringer Ingelheim Pharma Gmbh Co. Kg | Aerosol formulation for inhalation containing a tiotropium salt |
| US20050220720A1 (en) * | 2002-05-02 | 2005-10-06 | David Edwards | Formulations limiting spread of pulmonary infections |
| WO2003092654A1 (en) | 2002-05-02 | 2003-11-13 | President And Fellows Of Harvard College | Formulations limiting spread of pulmonary infections |
| US20040048886A1 (en) * | 2002-07-09 | 2004-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on new anticholinergics and NK1 receptor antagonists |
| US20040058950A1 (en) * | 2002-07-09 | 2004-03-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
| RS51396B (en) * | 2002-08-14 | 2011-02-28 | Boehringer Ingelheim Pharma Gmbh & Co.Kg. | AEROSOLIC INHALATION FORMULATION CONTAINING ANTICHOLINERGIC |
| US7056916B2 (en) * | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| US8912174B2 (en) | 2003-04-16 | 2014-12-16 | Mylan Pharmaceuticals Inc. | Formulations and methods for treating rhinosinusitis |
| GB2400554B (en) * | 2003-04-16 | 2007-04-18 | George Margetts | Treatment of angiotensin II-induced cardiovascular disease |
| US9808471B2 (en) * | 2003-04-16 | 2017-11-07 | Mylan Specialty Lp | Nasal pharmaceutical formulations and methods of using the same |
| US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
| US20050107417A1 (en) * | 2003-07-28 | 2005-05-19 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising a novel anticholinergic and a betamimetic |
| US20050042176A1 (en) * | 2003-07-28 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising a novel anticholinergic and a steroid |
| US20050025718A1 (en) * | 2003-07-31 | 2005-02-03 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising an anticholinergic and a betamimetic |
| US20050059643A1 (en) * | 2003-08-05 | 2005-03-17 | Boehringer Ingelheim International Gmbh | Medicaments for inhalation comprising a steroid and a betamimetic |
| DE102004001451A1 (de) | 2004-01-08 | 2005-08-11 | Boehringer Ingelheim International Gmbh | Vorrichtung zum Haltern eines fluidischen Bauteiles |
| US20050203088A1 (en) * | 2004-01-09 | 2005-09-15 | Boehringer Ingelheim International Gmbh | Medicament combinations based on scopine- or tropene acid esters with EGFR-kinase inhibitors |
| US20050207983A1 (en) * | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
| US20050272726A1 (en) * | 2004-04-22 | 2005-12-08 | Boehringer Ingelheim International Gmbh | Novel medicaments for the treatment of respiratory diseases |
| US7220742B2 (en) | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
| US20050255050A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Powder formulations for inhalation, comprising enantiomerically pure beta agonists |
| US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
| PT1756594E (pt) | 2004-05-25 | 2010-06-16 | Enel Distribuzione Spa | Método e dispositivo para detectar a fase de cablagem de uma tensão de fase arbitrária desconhecida relativamente à tensão da fase de referência |
| WO2005123064A1 (en) * | 2004-06-10 | 2005-12-29 | Board Of Trustees Of Michigan State University | Adrenergic complement inhaler comprising compounds such as ascorbates tocopherols or polycaboxylic acid chelators |
| US8627821B2 (en) * | 2005-01-10 | 2014-01-14 | Pulmatrix, Inc. | Method and device for decreasing contamination |
| NZ593475A (en) * | 2005-05-18 | 2012-12-21 | Pulmatrix Inc | Calcium salts for reducing exhalation of infectious bioaerosol particles |
| MX2008001976A (es) * | 2005-08-15 | 2008-03-25 | Boehringer Ingelheim Int | Procedimiento para la preparacion de betamimeticos. |
| CN101296700A (zh) * | 2005-11-09 | 2008-10-29 | 贝林格尔·英格海姆国际有限公司 | 吸入用气雾剂制剂 |
| US20100056559A1 (en) * | 2006-05-19 | 2010-03-04 | Boehringer Ingelheim International Gmbh | Propellant-free aerosol formulation for inhalation |
| EP2026784A1 (de) * | 2006-05-19 | 2009-02-25 | Boehringer Ingelheim International GmbH | Aerosolformulierung enthaltend ipratropiumbromid und salbutamolsulfat |
| DE102006023756A1 (de) * | 2006-05-20 | 2007-11-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ethanolhaltige Aerosolformulierung für die Inhalation |
| UY30543A1 (es) * | 2006-08-18 | 2008-03-31 | Boehringer Ingelheim Int | Formulacion de aerosol para la inhalacion de beta- agonistas |
| UY30542A1 (es) * | 2006-08-18 | 2008-03-31 | Boehringer Ingelheim Int | Formulacion de aerosol para la inhalacion de agonistas beta |
| PE20080425A1 (es) * | 2006-08-22 | 2008-06-16 | Boehringer Ingelheim Int | Formulacion aerosol para la inhalacion de beta-agonistas |
| US20090071686A1 (en) * | 2007-09-13 | 2009-03-19 | Medtronic, Inc. | Medical electrical lead |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| EP2093219A1 (de) | 2008-02-22 | 2009-08-26 | Boehringer Ingelheim International Gmbh | Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel |
| EP2414560B1 (de) | 2009-03-31 | 2013-10-23 | Boehringer Ingelheim International GmbH | Verfahren zur beschichtung einer oberfläche eines bauteils |
| JP5763053B2 (ja) | 2009-05-18 | 2015-08-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アダプタ、吸入器具及びアトマイザ |
| JP5658268B2 (ja) | 2009-11-25 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2011064164A1 (en) | 2009-11-25 | 2011-06-03 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2011160932A1 (en) | 2010-06-24 | 2011-12-29 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2464346A1 (en) | 2010-08-30 | 2012-06-20 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
| AU2011296343B2 (en) | 2010-08-30 | 2015-12-10 | Pulmatrix Operating Company, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| CN107096014B (zh) | 2010-09-29 | 2022-07-15 | 普马特里克斯营业公司 | 吸入用单价金属阳离子干粉剂 |
| DK2621488T3 (en) | 2010-09-29 | 2019-03-04 | Pulmatrix Operating Co Inc | CATIONIC DRY POWDER |
| WO2012130757A1 (de) | 2011-04-01 | 2012-10-04 | Boehringer Ingelheim International Gmbh | Medizinisches gerät mit behälter |
| ES2612257T3 (es) * | 2011-05-03 | 2017-05-16 | Chiesi Farmaceutici S.P.A. | Formulación de suspensión mejorada de dipropionato de beclometasona para administración mediante inhalación |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| CN104487075A (zh) | 2012-02-29 | 2015-04-01 | 普马特里克斯公司 | 可吸入干粉剂 |
| WO2013152894A1 (de) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Zerstäuber mit kodiermitteln |
| RU2479304C1 (ru) * | 2012-05-29 | 2013-04-20 | Шолекс Девелопмент Гмбх, | Стабильный раствор фенотерола гидробромида |
| RU2493827C1 (ru) * | 2012-10-03 | 2013-09-27 | Шолекс Девелопмент Гмбх | Стабильный комбинированный раствор фенотерола гидробромида и ипратропия бромида |
| CN105324106A (zh) | 2013-04-01 | 2016-02-10 | 普马特里克斯营业公司 | 噻托铵干粉 |
| EP2835146B1 (en) | 2013-08-09 | 2020-09-30 | Boehringer Ingelheim International GmbH | Nebulizer |
| JP6643231B2 (ja) | 2013-08-09 | 2020-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ネブライザ |
| WO2015065223A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Стабильный раствор фенотерола гидробромида |
| WO2015065219A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Раствор ипратропия бромида |
| PL3139984T3 (pl) | 2014-05-07 | 2021-11-08 | Boehringer Ingelheim International Gmbh | Nebulizator |
| JP6580070B2 (ja) | 2014-05-07 | 2019-09-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 容器、ネブライザ、及び使用 |
| LT3928818T (lt) | 2014-05-07 | 2023-03-27 | Boehringer Ingelheim International Gmbh | Purkštuvas ir talpa |
| EP3297607B1 (en) * | 2015-05-18 | 2020-07-22 | Glenmark Specialty S.A. | Tiotropium inhalation solution for nebulization |
| CN109925300A (zh) * | 2017-12-19 | 2019-06-25 | 北京盈科瑞创新药物研究有限公司 | 一种福多司坦雾化吸入用溶液制剂及其制备方法 |
| CN115989032A (zh) | 2020-07-31 | 2023-04-18 | 化学研究有限公司 | 用于吸入施用的组合疗法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX3864E (es) * | 1975-05-27 | 1981-08-26 | Syntex Corp | Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona |
| DE3431727A1 (de) * | 1984-08-29 | 1986-03-13 | Robugen GmbH Pharmazeutische Fabrik, 7300 Esslingen | Nasenspray gegen schnupfen und grippe mit einem gehalt an zinkglukonat |
| JPH0645538B2 (ja) * | 1987-09-30 | 1994-06-15 | 日本化薬株式会社 | ニトログリセリンスプレー剤 |
| GB8825892D0 (en) * | 1988-11-04 | 1988-12-07 | Fisons Plc | Pharmaceutical composition |
| SG45171A1 (en) * | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
| WO1992006726A1 (en) * | 1990-10-16 | 1992-04-30 | Mayor Pharmaceutical Laboratories, Inc. | Vitamin-mineral treatment methods and compositions |
| WO1994013263A1 (en) * | 1992-12-09 | 1994-06-23 | Jager Paul D | Stabilized medicinal aerosol solution formulations |
| TW431888B (en) * | 1994-02-03 | 2001-05-01 | Schering Plough Healthcare | Nasal spray compositions |
| EP0726075A1 (en) * | 1995-02-08 | 1996-08-14 | Therapicon Srl | Pharmaceutical non-inorganic saline solutions for endonasal administration |
| ES2183001T3 (es) * | 1995-06-27 | 2003-03-16 | Boehringer Ingelheim Pharma | Nuevo preparado medicamentoso estable para la produccion de aerosoles exentos de gas propulsor. |
| DE19536916A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Kg | Inhalative Applikation von 2-Amino-6n-propyl-amino-4,5,6,7-tetrahydrobenzothiazol, insbesondere seines (-)-Enantiomeren, sowie deren pharmakologisch verträgliche Säureadditionssalze |
| DE19536902A1 (de) * | 1995-10-04 | 1997-04-10 | Boehringer Ingelheim Int | Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung |
| DE19620509A1 (de) * | 1996-05-22 | 1997-11-27 | Hoechst Ag | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
| EP0808627A2 (de) * | 1996-05-22 | 1997-11-26 | Hoechst Aktiengesellschaft | Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen |
| US5976573A (en) * | 1996-07-03 | 1999-11-02 | Rorer Pharmaceutical Products Inc. | Aqueous-based pharmaceutical composition |
| DE19644646A1 (de) * | 1996-10-26 | 1998-04-30 | Mann & Hummel Filter | Filter, insbesondere zur Filtrierung des Schmieröls einer Brennkraftmaschine |
| US20030215396A1 (en) * | 1999-09-15 | 2003-11-20 | Boehringer Ingelheim Pharma Kg | Method for the production of propellant gas-free aerosols from aqueous medicament preparations |
| US20060239930A1 (en) * | 1997-08-04 | 2006-10-26 | Herbert Lamche | Process for nebulizing aqueous compositions containing highly concentrated insulin |
| DE19847969A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Lagerfähig flüssige Formulierung mit Formoterol |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| US20020137764A1 (en) * | 2000-10-31 | 2002-09-26 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
| US20020111363A1 (en) * | 2000-10-31 | 2002-08-15 | Karin Drechsel | Inhalable formulation of a solution containing a tiotropium salt |
| US20020193392A1 (en) * | 2000-11-13 | 2002-12-19 | Christel Schmelzer | Pharmaceutical compositions based on tiotropium salts of salts of salmeterol |
| US20040019073A1 (en) * | 2002-04-11 | 2004-01-29 | Boehringer Ingelheim Pharma Gmbh Co. Kg | Aerosol formulation for inhalation containing a tiotropium salt |
-
1996
- 1996-12-20 DE DE19653969A patent/DE19653969A1/de not_active Ceased
-
1997
- 1997-12-16 US US09/331,023 patent/US20010008632A1/en not_active Abandoned
- 1997-12-16 IL IL13046497A patent/IL130464A/en not_active IP Right Cessation
- 1997-12-16 KR KR10-1999-7005535A patent/KR100496723B1/ko not_active IP Right Cessation
- 1997-12-16 PT PT97952949T patent/PT946146E/pt unknown
- 1997-12-16 CA CA002275392A patent/CA2275392C/en not_active Expired - Lifetime
- 1997-12-16 EE EEP199900307A patent/EE03949B1/xx unknown
- 1997-12-16 DK DK97952949T patent/DK0946146T3/da active
- 1997-12-16 SI SI9730537T patent/SI0946146T1/xx unknown
- 1997-12-16 TR TR1999/01408T patent/TR199901408T2/xx unknown
- 1997-12-16 AT AT97952949T patent/ATE235887T1/de active
- 1997-12-16 RU RU99116025/15A patent/RU2219906C2/ru active
- 1997-12-16 ES ES97952949T patent/ES2196388T3/es not_active Expired - Lifetime
- 1997-12-16 RS YUP-284/99A patent/RS49803B/sr unknown
- 1997-12-16 ID IDW990549A patent/ID22481A/id unknown
- 1997-12-16 CN CN97180735A patent/CN1097455C/zh not_active Expired - Lifetime
- 1997-12-16 EP EP97952949A patent/EP0946146B1/de not_active Expired - Lifetime
- 1997-12-16 NZ NZ336825A patent/NZ336825A/en not_active IP Right Cessation
- 1997-12-16 PE PE1997001120A patent/PE32899A1/es not_active IP Right Cessation
- 1997-12-16 UA UA99074151A patent/UA64736C2/ru unknown
- 1997-12-16 JP JP52833698A patent/JP4659160B2/ja not_active Expired - Lifetime
- 1997-12-16 AU AU56636/98A patent/AU740543B2/en not_active Expired
- 1997-12-16 SK SK814-99A patent/SK282910B6/sk not_active IP Right Cessation
- 1997-12-16 HU HU0000520A patent/HU227012B1/hu unknown
- 1997-12-16 BR BRPI9713596A patent/BRPI9713596C1/pt not_active IP Right Cessation
- 1997-12-16 WO PCT/EP1997/007062 patent/WO1998027959A2/de active IP Right Grant
- 1997-12-16 HU HU0600044A patent/HU228494B1/hu unknown
- 1997-12-16 EP EP02010785A patent/EP1230916A3/de not_active Withdrawn
- 1997-12-16 PL PL97334185A patent/PL189511B1/pl unknown
- 1997-12-16 DE DE59709722T patent/DE59709722D1/de not_active Expired - Lifetime
- 1997-12-17 UY UY24813A patent/UY24813A1/es not_active IP Right Cessation
- 1997-12-18 ZA ZA9711370A patent/ZA9711370B/xx unknown
- 1997-12-18 HR HR970694A patent/HRP970694B1/xx not_active IP Right Cessation
- 1997-12-18 EG EG135397A patent/EG23981A/xx active
- 1997-12-18 CO CO97074008A patent/CO4920211A1/es unknown
- 1997-12-19 MY MYPI97006172A patent/MY124547A/en unknown
- 1997-12-19 AR ARP970106019A patent/AR008721A1/es active IP Right Grant
- 1997-12-20 TW TW086119428A patent/TW438605B/zh not_active IP Right Cessation
- 1997-12-30 SA SA97180756A patent/SA97180756B1/ar unknown
-
1999
- 1999-06-10 BG BG103482A patent/BG64433B1/bg active Active
- 1999-06-18 NO NO19993004A patent/NO320652B1/no not_active IP Right Cessation
-
2000
- 2000-03-31 HK HK00101995A patent/HK1022846A1/xx not_active IP Right Cessation
-
2008
- 2008-12-18 US US12/338,812 patent/US20090099225A1/en not_active Abandoned
-
2009
- 2009-03-30 US US12/413,828 patent/US20090185983A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2510273C2 (ru) * | 2007-12-04 | 2014-03-27 | Пьер Фабр Медикамент | Меквитазин для лечения или предотвращения патологий, в которых задействованы н4 рецепторы гистамина |
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