RS51396B - Aerosol formulation for inhalation containing an anticholinergic agent - Google Patents

Aerosol formulation for inhalation containing an anticholinergic agent

Info

Publication number
RS51396B
RS51396B YUP-2005/0074A YUP20050074A RS51396B RS 51396 B RS51396 B RS 51396B YU P20050074 A YUP20050074 A YU P20050074A RS 51396 B RS51396 B RS 51396B
Authority
RS
Serbia
Prior art keywords
inhalation
aerosol formulation
anticholinergic agent
aza
oxa
Prior art date
Application number
YUP-2005/0074A
Other languages
Serbian (sr)
Inventor
Friedrich Schmidt
Original Assignee
Boehringer Ingelheim Pharma Gmbh & Co.Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31979448&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RS51396(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE10237232A external-priority patent/DE10237232A1/en
Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg. filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg.
Publication of RS20050074A publication Critical patent/RS20050074A/en
Publication of RS51396B publication Critical patent/RS51396B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Aqueous composition (A) for inhalation contains as only active ingredient a tricyclo-oxa-aza-nonane derivative (I), at least one acid and optionally other auxiliaries and/or complexing agents. Aqueous composition (A) for inhalation contains as only active ingredient a tricylo-oxa-aza-nonane derivative of formula (I), at least one acid and optionally other auxiliaries and/or complexing agents. [Image] X : chloride, bromide, iodide, sulfate, phosphate, methanesulfonate, nitrate, maleate, acetate, citrate, fumarate, tartrate, oxalate, succinate, benzoate or p-toluenesulfonate. An independent claim is also included for an inhalation kit containing (A) and an inhaler for nebulization. ACTIVITY : Antiasthmatic. No details of tests for antiasthmatic activity are given. MECHANISM OF ACTION : Anticholinergic.
YUP-2005/0074A 2002-08-14 2003-07-25 Aerosol formulation for inhalation containing an anticholinergic agent RS51396B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10237232A DE10237232A1 (en) 2002-08-14 2002-08-14 Aqueous solution for inhalation, useful for treating respiratory disease, contains anticholinergic tricyclo-oxa-aza-nonane derivative and requires no propellant
DE10240257 2002-08-31
PCT/EP2003/008221 WO2004022052A1 (en) 2002-08-14 2003-07-25 Aerosol formulation for inhalation containing an anticholinergic agent

Publications (2)

Publication Number Publication Date
RS20050074A RS20050074A (en) 2007-09-21
RS51396B true RS51396B (en) 2011-02-28

Family

ID=31979448

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2005/0074A RS51396B (en) 2002-08-14 2003-07-25 Aerosol formulation for inhalation containing an anticholinergic agent

Country Status (31)

Country Link
EP (2) EP1908468A1 (en)
JP (1) JP4602767B2 (en)
KR (1) KR101060972B1 (en)
CN (1) CN1674887A (en)
AT (1) ATE400265T1 (en)
AU (1) AU2003298473B9 (en)
BR (1) BR0313457A (en)
CA (1) CA2495275C (en)
CY (1) CY1108776T1 (en)
DE (1) DE50310117D1 (en)
DK (1) DK1530464T3 (en)
EA (1) EA009936B1 (en)
EC (1) ECSP055600A (en)
ES (1) ES2305479T3 (en)
HR (1) HRP20050132A2 (en)
IL (1) IL166814A (en)
MX (1) MXPA05001595A (en)
MY (1) MY142579A (en)
NO (1) NO20051287D0 (en)
NZ (1) NZ538743A (en)
PE (1) PE20040372A1 (en)
PL (1) PL375511A1 (en)
PT (1) PT1530464E (en)
RS (1) RS51396B (en)
SA (1) SA03240265B1 (en)
SI (1) SI1530464T1 (en)
TW (1) TWI317279B (en)
UA (1) UA81775C2 (en)
UY (1) UY27938A1 (en)
WO (1) WO2004022052A1 (en)
ZA (1) ZA200410325B (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004038885A1 (en) * 2004-08-10 2006-02-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
DE102005001297A1 (en) * 2005-01-12 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
DE102005055960A1 (en) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
DE102005055957A1 (en) * 2005-11-24 2007-07-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
DE102005055963A1 (en) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
DE102005055958A1 (en) * 2005-11-24 2007-07-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation containing an anticholinergic
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
EP2662472B1 (en) 2009-03-31 2019-02-27 Boehringer Ingelheim International Gmbh Method for coating a surface of a component
US9265910B2 (en) 2009-05-18 2016-02-23 Boehringer Ingelheim International Gmbh Adapter, inhalation device, and nebulizer
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
EP2504052B1 (en) 2009-11-25 2022-07-27 Boehringer Ingelheim International GmbH Nebulizer
JP5658268B2 (en) 2009-11-25 2015-01-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Nebulizer
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
EP2694220B1 (en) 2011-04-01 2020-05-06 Boehringer Ingelheim International GmbH Medical device comprising a container
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (en) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Atomiser with coding means
EP3030298B1 (en) 2013-08-09 2017-10-11 Boehringer Ingelheim International GmbH Nebulizer
ES2836977T3 (en) 2013-08-09 2021-06-28 Boehringer Ingelheim Int Nebulizer
US9877486B2 (en) 2014-01-31 2018-01-30 AgBiome, Inc. Methods of growing plants using modified biological control agents
CN106170207B (en) 2014-01-31 2019-12-27 农业生物群落股份有限公司 Modified biological control agents and uses thereof
DK3139984T3 (en) 2014-05-07 2021-07-19 Boehringer Ingelheim Int Atomizer
ES2954961T3 (en) 2014-05-07 2023-11-27 Boehringer Ingelheim Int Unit, nebulizer and method
RS64124B1 (en) 2014-05-07 2023-05-31 Boehringer Ingelheim Int Nebulizer and container

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
DE19653969A1 (en) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg New aqueous pharmaceutical preparation for the production of propellant-free aerosols
AU2000250701B2 (en) * 2000-05-22 2004-07-01 Chiesi Farmaceutici S.P.A. Stable pharmaceutical solution formulations for pressurised metered dose inhalers
DE10050994A1 (en) * 2000-10-14 2002-04-18 Boehringer Ingelheim Pharma New diphenylalkanoic acid azabicyclooctane ester quaternary salts useful as anticholinergic agents, especially in treatment of asthma and chronic obstructive pulmonary disease
DE10063957A1 (en) * 2000-12-20 2002-06-27 Boehringer Ingelheim Pharma New drug compositions based on anticholinergics and dopamine agonists
DE10200943A1 (en) * 2002-01-12 2003-07-24 Boehringer Ingelheim Pharma Process for the preparation of scopine esters

Also Published As

Publication number Publication date
IL166814A0 (en) 2006-01-15
NO20051287L (en) 2005-03-11
HRP20050132A2 (en) 2006-05-31
SI1530464T1 (en) 2008-12-31
DK1530464T3 (en) 2008-09-08
EA009936B1 (en) 2008-04-28
EP1530464B1 (en) 2008-07-09
EP1530464A1 (en) 2005-05-18
DE50310117D1 (en) 2008-08-21
EP1908468A1 (en) 2008-04-09
JP2006506345A (en) 2006-02-23
AU2003298473A1 (en) 2004-03-29
PT1530464E (en) 2008-08-28
UY27938A1 (en) 2004-03-31
NZ538743A (en) 2006-05-26
WO2004022052A1 (en) 2004-03-18
EA200500292A1 (en) 2005-10-27
NO20051287D0 (en) 2005-03-11
TW200406213A (en) 2004-05-01
KR101060972B1 (en) 2011-09-01
AU2003298473B2 (en) 2009-04-23
ES2305479T3 (en) 2008-11-01
SA03240265B1 (en) 2009-11-10
IL166814A (en) 2010-11-30
MY142579A (en) 2010-12-15
MXPA05001595A (en) 2005-04-25
JP4602767B2 (en) 2010-12-22
CY1108776T1 (en) 2014-04-09
PE20040372A1 (en) 2004-08-03
CN1674887A (en) 2005-09-28
BR0313457A (en) 2005-06-21
TWI317279B (en) 2009-11-21
PL375511A1 (en) 2005-11-28
CA2495275C (en) 2012-04-17
ZA200410325B (en) 2006-10-25
CA2495275A1 (en) 2004-03-18
KR20050049478A (en) 2005-05-25
ATE400265T1 (en) 2008-07-15
RS20050074A (en) 2007-09-21
ECSP055600A (en) 2005-04-18
UA81775C2 (en) 2008-02-11
AU2003298473B9 (en) 2011-06-09

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