HRP20050132A2 - Aerosol formulation for inhalation containing an anticholinergic agent - Google Patents
Aerosol formulation for inhalation containing an anticholinergic agentInfo
- Publication number
- HRP20050132A2 HRP20050132A2 HR20050132A HRP20050132A HRP20050132A2 HR P20050132 A2 HRP20050132 A2 HR P20050132A2 HR 20050132 A HR20050132 A HR 20050132A HR P20050132 A HRP20050132 A HR P20050132A HR P20050132 A2 HRP20050132 A2 HR P20050132A2
- Authority
- HR
- Croatia
- Prior art keywords
- inhalation
- aerosol formulation
- anticholinergic agent
- aza
- oxa
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Aqueous composition (A) for inhalation contains as only active ingredient a tricyclo-oxa-aza-nonane derivative (I), at least one acid and optionally other auxiliaries and/or complexing agents. Aqueous composition (A) for inhalation contains as only active ingredient a tricylo-oxa-aza-nonane derivative of formula (I), at least one acid and optionally other auxiliaries and/or complexing agents. [Image] X : chloride, bromide, iodide, sulfate, phosphate, methanesulfonate, nitrate, maleate, acetate, citrate, fumarate, tartrate, oxalate, succinate, benzoate or p-toluenesulfonate. An independent claim is also included for an inhalation kit containing (A) and an inhaler for nebulization. ACTIVITY : Antiasthmatic. No details of tests for antiasthmatic activity are given. MECHANISM OF ACTION : Anticholinergic.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10237232A DE10237232A1 (en) | 2002-08-14 | 2002-08-14 | Aqueous solution for inhalation, useful for treating respiratory disease, contains anticholinergic tricyclo-oxa-aza-nonane derivative and requires no propellant |
| DE10240257 | 2002-08-31 | ||
| PCT/EP2003/008221 WO2004022052A1 (en) | 2002-08-14 | 2003-07-25 | Aerosol formulation for inhalation containing an anticholinergic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20050132A2 true HRP20050132A2 (en) | 2006-05-31 |
Family
ID=31979448
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20050132A HRP20050132A2 (en) | 2002-08-14 | 2005-02-11 | Aerosol formulation for inhalation containing an anticholinergic agent |
Country Status (31)
| Country | Link |
|---|---|
| EP (2) | EP1908468A1 (en) |
| JP (1) | JP4602767B2 (en) |
| KR (1) | KR101060972B1 (en) |
| CN (1) | CN1674887A (en) |
| AT (1) | ATE400265T1 (en) |
| AU (1) | AU2003298473B9 (en) |
| BR (1) | BR0313457A (en) |
| CA (1) | CA2495275C (en) |
| CY (1) | CY1108776T1 (en) |
| DE (1) | DE50310117D1 (en) |
| DK (1) | DK1530464T3 (en) |
| EA (1) | EA009936B1 (en) |
| EC (1) | ECSP055600A (en) |
| ES (1) | ES2305479T3 (en) |
| HR (1) | HRP20050132A2 (en) |
| IL (1) | IL166814A (en) |
| MX (1) | MXPA05001595A (en) |
| MY (1) | MY142579A (en) |
| NO (1) | NO20051287D0 (en) |
| NZ (1) | NZ538743A (en) |
| PE (1) | PE20040372A1 (en) |
| PL (1) | PL375511A1 (en) |
| PT (1) | PT1530464E (en) |
| RS (1) | RS51396B (en) |
| SA (1) | SA03240265B1 (en) |
| SI (1) | SI1530464T1 (en) |
| TW (1) | TWI317279B (en) |
| UA (1) | UA81775C2 (en) |
| UY (1) | UY27938A1 (en) |
| WO (1) | WO2004022052A1 (en) |
| ZA (1) | ZA200410325B (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004038885A1 (en) * | 2004-08-10 | 2006-02-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
| DE102005001297A1 (en) * | 2005-01-12 | 2006-07-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
| DE102005055960A1 (en) * | 2005-11-24 | 2007-07-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
| DE102005055957A1 (en) * | 2005-11-24 | 2007-07-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
| DE102005055963A1 (en) * | 2005-11-24 | 2007-07-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
| DE102005055958A1 (en) * | 2005-11-24 | 2007-07-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for inhalation containing an anticholinergic |
| EP2077132A1 (en) | 2008-01-02 | 2009-07-08 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device, storage device and method for dispensing a formulation |
| EP2662472B1 (en) | 2009-03-31 | 2019-02-27 | Boehringer Ingelheim International Gmbh | Method for coating a surface of a component |
| US9265910B2 (en) | 2009-05-18 | 2016-02-23 | Boehringer Ingelheim International Gmbh | Adapter, inhalation device, and nebulizer |
| US10016568B2 (en) | 2009-11-25 | 2018-07-10 | Boehringer Ingelheim International Gmbh | Nebulizer |
| EP2504052B1 (en) | 2009-11-25 | 2022-07-27 | Boehringer Ingelheim International GmbH | Nebulizer |
| JP5658268B2 (en) | 2009-11-25 | 2015-01-21 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Nebulizer |
| EP2585151B1 (en) | 2010-06-24 | 2018-04-04 | Boehringer Ingelheim International GmbH | Nebulizer |
| EP2694220B1 (en) | 2011-04-01 | 2020-05-06 | Boehringer Ingelheim International GmbH | Medical device comprising a container |
| US9827384B2 (en) | 2011-05-23 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Nebulizer |
| WO2013152894A1 (en) | 2012-04-13 | 2013-10-17 | Boehringer Ingelheim International Gmbh | Atomiser with coding means |
| EP3030298B1 (en) | 2013-08-09 | 2017-10-11 | Boehringer Ingelheim International GmbH | Nebulizer |
| ES2836977T3 (en) | 2013-08-09 | 2021-06-28 | Boehringer Ingelheim Int | Nebulizer |
| US9877486B2 (en) | 2014-01-31 | 2018-01-30 | AgBiome, Inc. | Methods of growing plants using modified biological control agents |
| CN106170207B (en) | 2014-01-31 | 2019-12-27 | 农业生物群落股份有限公司 | Modified biological control agents and uses thereof |
| DK3139984T3 (en) | 2014-05-07 | 2021-07-19 | Boehringer Ingelheim Int | Atomizer |
| ES2954961T3 (en) | 2014-05-07 | 2023-11-27 | Boehringer Ingelheim Int | Unit, nebulizer and method |
| RS64124B1 (en) | 2014-05-07 | 2023-05-31 | Boehringer Ingelheim Int | Nebulizer and container |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG45171A1 (en) * | 1990-03-21 | 1998-01-16 | Boehringer Ingelheim Int | Atomising devices and methods |
| DE19653969A1 (en) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | New aqueous pharmaceutical preparation for the production of propellant-free aerosols |
| AU2000250701B2 (en) * | 2000-05-22 | 2004-07-01 | Chiesi Farmaceutici S.P.A. | Stable pharmaceutical solution formulations for pressurised metered dose inhalers |
| DE10050994A1 (en) * | 2000-10-14 | 2002-04-18 | Boehringer Ingelheim Pharma | New diphenylalkanoic acid azabicyclooctane ester quaternary salts useful as anticholinergic agents, especially in treatment of asthma and chronic obstructive pulmonary disease |
| DE10063957A1 (en) * | 2000-12-20 | 2002-06-27 | Boehringer Ingelheim Pharma | New drug compositions based on anticholinergics and dopamine agonists |
| DE10200943A1 (en) * | 2002-01-12 | 2003-07-24 | Boehringer Ingelheim Pharma | Process for the preparation of scopine esters |
-
2003
- 2003-07-25 CA CA2495275A patent/CA2495275C/en not_active Expired - Fee Related
- 2003-07-25 AT AT03740479T patent/ATE400265T1/en active
- 2003-07-25 SI SI200331363T patent/SI1530464T1/en unknown
- 2003-07-25 DK DK03740479T patent/DK1530464T3/en active
- 2003-07-25 AU AU2003298473A patent/AU2003298473B9/en not_active Ceased
- 2003-07-25 EA EA200500292A patent/EA009936B1/en not_active IP Right Cessation
- 2003-07-25 UA UAA200502195A patent/UA81775C2/en unknown
- 2003-07-25 ES ES03740479T patent/ES2305479T3/en not_active Expired - Lifetime
- 2003-07-25 PT PT03740479T patent/PT1530464E/en unknown
- 2003-07-25 NZ NZ538743A patent/NZ538743A/en not_active IP Right Cessation
- 2003-07-25 BR BR0313457-1A patent/BR0313457A/en not_active Expired - Fee Related
- 2003-07-25 EP EP07121698A patent/EP1908468A1/en not_active Withdrawn
- 2003-07-25 KR KR1020057002504A patent/KR101060972B1/en not_active IP Right Cessation
- 2003-07-25 EP EP03740479A patent/EP1530464B1/en not_active Expired - Lifetime
- 2003-07-25 MX MXPA05001595A patent/MXPA05001595A/en active IP Right Grant
- 2003-07-25 JP JP2004533274A patent/JP4602767B2/en not_active Expired - Fee Related
- 2003-07-25 DE DE50310117T patent/DE50310117D1/en not_active Expired - Lifetime
- 2003-07-25 PL PL03375511A patent/PL375511A1/en unknown
- 2003-07-25 WO PCT/EP2003/008221 patent/WO2004022052A1/en active IP Right Grant
- 2003-07-25 RS YUP-2005/0074A patent/RS51396B/en unknown
- 2003-07-25 CN CNA038192004A patent/CN1674887A/en active Pending
- 2003-08-12 PE PE2003000803A patent/PE20040372A1/en not_active Application Discontinuation
- 2003-08-12 MY MYPI20033067A patent/MY142579A/en unknown
- 2003-08-13 TW TW092122269A patent/TWI317279B/en not_active IP Right Cessation
- 2003-08-14 UY UY27938A patent/UY27938A1/en not_active Application Discontinuation
- 2003-08-31 SA SA3240265A patent/SA03240265B1/en unknown
-
2004
- 2004-12-22 ZA ZA200410325A patent/ZA200410325B/en unknown
-
2005
- 2005-02-10 IL IL166814A patent/IL166814A/en not_active IP Right Cessation
- 2005-02-11 HR HR20050132A patent/HRP20050132A2/en not_active Application Discontinuation
- 2005-02-14 EC EC2005005600A patent/ECSP055600A/en unknown
- 2005-03-11 NO NO20051287A patent/NO20051287D0/en not_active Application Discontinuation
-
2008
- 2008-10-08 CY CY20081101114T patent/CY1108776T1/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| ARAI | Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20120626 Year of fee payment: 10 |
|
| OBST | Application withdrawn |