RU94038426A - Узко поли- и монодисперсный водорастворимый олигомер, фармацевтический препарат, способ получения олигомера, способ диагностики и/или лечения вирусных инфекций - Google Patents
Узко поли- и монодисперсный водорастворимый олигомер, фармацевтический препарат, способ получения олигомера, способ диагностики и/или лечения вирусных инфекцийInfo
- Publication number
- RU94038426A RU94038426A RU94038426/04A RU94038426A RU94038426A RU 94038426 A RU94038426 A RU 94038426A RU 94038426/04 A RU94038426/04 A RU 94038426/04A RU 94038426 A RU94038426 A RU 94038426A RU 94038426 A RU94038426 A RU 94038426A
- Authority
- RU
- Russia
- Prior art keywords
- oligomers
- oligomer
- narrowly
- poly
- diagnosis
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/795—Polymers containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/45—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/51—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/685—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen
- C08G63/6854—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen derived from polycarboxylic acids and polyhydroxy compounds
- C08G63/6856—Dicarboxylic acids and dihydroxy compounds
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/688—Polyesters containing atoms other than carbon, hydrogen and oxygen containing sulfur
- C08G63/6884—Polyesters containing atoms other than carbon, hydrogen and oxygen containing sulfur derived from polycarboxylic acids and polyhydroxy compounds
- C08G63/6886—Dicarboxylic acids and dihydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/692—Polyesters containing atoms other than carbon, hydrogen and oxygen containing phosphorus
- C08G63/6924—Polyesters containing atoms other than carbon, hydrogen and oxygen containing phosphorus derived from polycarboxylic acids and polyhydroxy compounds
- C08G63/6926—Dicarboxylic acids and dihydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/04—Aromatic polycarbonates
- C08G64/06—Aromatic polycarbonates not containing aliphatic unsaturation
- C08G64/08—Aromatic polycarbonates not containing aliphatic unsaturation containing atoms other than carbon, hydrogen or oxygen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/26—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from polyamines and polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G71/00—Macromolecular compounds obtained by reactions forming a ureide or urethane link, otherwise, than from isocyanate radicals in the main chain of the macromolecule
- C08G71/02—Polyureas
Abstract
Узко поли- и монодисперсные олигомеры настоящего изобретения являются полимочевинами, поликарбонатами, полиэфирами или полиамидами, имеющими довторность единицы от 3 до 50. Эти олигомеры являются водорастворимыми, предпочтительно имеют жесткий каркас, имеют повторяющиеся единицы, соединенные карбонильными связывающими составляющими, которые обладают анионными группами, проявляют преимущественно линейную геометрию, так что в водной среде между анионными группами существуют постоянные расстояния, и являются фармацевтически приемлемыми. Узко поли- и монодисперсные олигомеры применимы для лечения и/или диагностики СПИД и/или КСС или HSV инфекций.
Claims (1)
- Узко поли- и монодисперсные олигомеры настоящего изобретения являются полимочевинами, поликарбонатами, полиэфирами или полиамидами, имеющими довторность единицы от 3 до 50. Эти олигомеры являются водорастворимыми, предпочтительно имеют жесткий каркас, имеют повторяющиеся единицы, соединенные карбонильными связывающими составляющими, которые обладают анионными группами, проявляют преимущественно линейную геометрию, так что в водной среде между анионными группами существуют постоянные расстояния, и являются фармацевтически приемлемыми. Узко поли- и монодисперсные олигомеры применимы для лечения и/или диагностики СПИД и/или КСС или HSV инфекций.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/818,753 | 1992-01-09 | ||
US07/818,753 US5424063A (en) | 1992-01-09 | 1992-01-09 | Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process |
Publications (2)
Publication Number | Publication Date |
---|---|
RU94038426A true RU94038426A (ru) | 1996-07-20 |
RU2160746C2 RU2160746C2 (ru) | 2000-12-20 |
Family
ID=25226322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU94038426/04A RU2160746C2 (ru) | 1992-01-09 | 1993-01-07 | Узкополи- и монодисперсный водорастворимый олигомер, способ его получения, фармацевтический препарат, способ ингибирования активности вирусов |
Country Status (24)
Country | Link |
---|---|
US (4) | US5424063A (ru) |
EP (1) | EP0620833B1 (ru) |
JP (1) | JPH07509446A (ru) |
KR (1) | KR100255282B1 (ru) |
CN (1) | CN1049670C (ru) |
AP (1) | AP381A (ru) |
AT (1) | ATE159961T1 (ru) |
AU (1) | AU665056B2 (ru) |
CA (1) | CA2127356A1 (ru) |
CZ (1) | CZ282312B6 (ru) |
DE (1) | DE69315058T2 (ru) |
DK (1) | DK0620833T3 (ru) |
ES (1) | ES2110594T3 (ru) |
FI (1) | FI108459B (ru) |
GR (1) | GR3026019T3 (ru) |
HU (1) | HUT70831A (ru) |
IL (1) | IL104354A (ru) |
MX (1) | MX9300081A (ru) |
NO (1) | NO307610B1 (ru) |
NZ (1) | NZ246791A (ru) |
OA (1) | OA09962A (ru) |
RU (1) | RU2160746C2 (ru) |
WO (1) | WO1993014146A1 (ru) |
ZA (1) | ZA93136B (ru) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5670144A (en) * | 1990-07-09 | 1997-09-23 | Merrell Pharmaceuticals Inc. | Anti-herpes virus and cytomegalovirus polyester oligomers |
US5276182A (en) * | 1990-07-09 | 1994-01-04 | The Dow Chemical Company | Process for preparing polyurea oligomers |
EP0498095B1 (en) * | 1991-02-05 | 1995-01-04 | Merrell Dow Pharmaceuticals Inc. | Sulfonic stilbene derivatives in the treatment of viral diseases |
US5424063A (en) * | 1992-01-09 | 1995-06-13 | The Dow Chemical Company | Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process |
WO1994004165A1 (en) * | 1992-08-19 | 1994-03-03 | Merrell Dow Pharmaceuticals Inc. | Antiangiogenic oligomers |
US5614559A (en) * | 1993-11-23 | 1997-03-25 | Procept Inc. | Compound for inhibiting HIV infectivity |
IL112174A (en) * | 1994-01-03 | 1999-05-09 | Merrell Dow Pharma | Oligomers of polythioureas pharmaceutical compositions containing them and a process for their preparation |
DE19504913A1 (de) * | 1995-02-15 | 1996-08-22 | Basf Ag | Neue chiral neumatische Polyester |
WO1996025157A1 (en) * | 1995-02-17 | 1996-08-22 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
US5780483A (en) * | 1995-02-17 | 1998-07-14 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
US6005008A (en) * | 1996-02-16 | 1999-12-21 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
US5747639A (en) * | 1996-03-06 | 1998-05-05 | Amgen Boulder Inc. | Use of hydrophobic interaction chromatography to purify polyethylene glycols |
US6262113B1 (en) | 1996-03-20 | 2001-07-17 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
US6211373B1 (en) | 1996-03-20 | 2001-04-03 | Smithkline Beecham Corporation | Phenyl urea antagonists of the IL-8 receptor |
US6271261B1 (en) | 1996-06-27 | 2001-08-07 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
WO1997049680A1 (en) * | 1996-06-27 | 1997-12-31 | Smithkline Beecham Corporation | Il-8 receptor antagonists |
US6126919A (en) * | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
US6060235A (en) | 1997-09-19 | 2000-05-09 | Geltex Pharmaceuticals, Inc. | Antiviral polymers comprising acid functional groups and hydrophobic groups |
US6290946B1 (en) | 1999-05-13 | 2001-09-18 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders and antibacterial agents |
US6270755B1 (en) | 1999-05-13 | 2001-08-07 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders |
EP1214293A1 (en) | 1999-09-08 | 2002-06-19 | Guilford Pharmaceuticals Inc. | Non-peptidic cyclophilin binding compounds and their use |
CA2314494A1 (en) | 2000-05-02 | 2001-11-02 | Geltex Pharmaceuticals, Inc. | Anionic polymers as species specific antibacterial agents |
JP2004532187A (ja) | 2001-01-25 | 2004-10-21 | ギルフォード ファーマシュウティカルズ インコーポレイテッド | 三置換カルボサイクリックサイクロフィリン結合化合物とその用途 |
JP4170214B2 (ja) | 2001-03-08 | 2008-10-22 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア | 抗感染用剤としての表面両親媒性ポリマー |
EP2471526A3 (en) * | 2003-03-17 | 2012-12-12 | The Trustees Of The University Of Pennsylvania | Facially amphiphillic polymers and oligomers and uses thereof |
EP2468711A3 (en) | 2004-01-23 | 2012-09-19 | The Trustees Of The University Of Pennsylvania | Facially amphiphilic polyaryl and polarylalkynyl polymers and oligomers and uses thereof |
US10017462B1 (en) * | 2018-03-05 | 2018-07-10 | The Florida International University Board Of Trustees | Antimicrobial poly(guanylurea)s |
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GB781479A (en) * | 1953-08-27 | 1957-08-21 | Ciba Ltd | New polyureas and process for making them |
US2833744A (en) * | 1953-08-27 | 1958-05-06 | Ciba Pharm Prod Inc | Polyureas and process of preparing same |
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JPS56147822A (en) * | 1980-04-17 | 1981-11-17 | Dainippon Ink & Chem Inc | Preparation of novel water-soluble or water-dispersible polyester resin |
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JPS5719662A (en) * | 1980-07-09 | 1982-02-01 | Fuji Photo Film Co Ltd | Preparation of microcapsule reagent for immune reaction |
DE3026575A1 (de) * | 1980-07-12 | 1982-02-04 | Bayer Ag, 5090 Leverkusen | Antitumoral wirkende mittel |
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US4783446A (en) * | 1985-11-22 | 1988-11-08 | Neushul Mariculture Incorporated | Method for the treatment of AIDS virus and other retroviruses |
US4895660A (en) * | 1986-07-14 | 1990-01-23 | The Dow Chemical Company | Water-soluble aromatic polyamides and polyureas |
DE3626309A1 (de) * | 1986-08-02 | 1988-02-18 | Stockhausen Chem Fab Gmbh | Antivirusmittel |
DE3744119A1 (de) * | 1987-12-24 | 1989-07-06 | Basf Ag | Verwendung von polysulfatierten heparinen |
US5670144A (en) * | 1990-07-09 | 1997-09-23 | Merrell Pharmaceuticals Inc. | Anti-herpes virus and cytomegalovirus polyester oligomers |
US5276182A (en) * | 1990-07-09 | 1994-01-04 | The Dow Chemical Company | Process for preparing polyurea oligomers |
FR2669535A1 (fr) * | 1990-11-26 | 1992-05-29 | Medgenix Group Sa | Utilisation a titre de medicament de macromolecules polysulfonees. |
EP0498095B1 (en) * | 1991-02-05 | 1995-01-04 | Merrell Dow Pharmaceuticals Inc. | Sulfonic stilbene derivatives in the treatment of viral diseases |
US5424063A (en) * | 1992-01-09 | 1995-06-13 | The Dow Chemical Company | Narrow poly- and mono-dispersed anionic oligomers, and their uses, formulations and process |
KR100275843B1 (ko) * | 1992-02-20 | 2000-12-15 | 슈테펜엘.네스비트 | 설폰산 유도체 및 이를 포함하는 약제학적 조성물 |
US5460807A (en) * | 1992-08-19 | 1995-10-24 | Merrell Dow Pharmaceuticals Inc. | Antiproliferative oligomers |
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1992
- 1992-01-09 US US07/818,753 patent/US5424063A/en not_active Expired - Fee Related
-
1993
- 1993-01-07 KR KR1019940702360A patent/KR100255282B1/ko not_active IP Right Cessation
- 1993-01-07 RU RU94038426/04A patent/RU2160746C2/ru not_active IP Right Cessation
- 1993-01-07 ES ES93902971T patent/ES2110594T3/es not_active Expired - Lifetime
- 1993-01-07 EP EP93902971A patent/EP0620833B1/en not_active Expired - Lifetime
- 1993-01-07 WO PCT/US1993/000094 patent/WO1993014146A1/en active IP Right Grant
- 1993-01-07 CA CA002127356A patent/CA2127356A1/en not_active Abandoned
- 1993-01-07 AU AU34360/93A patent/AU665056B2/en not_active Ceased
- 1993-01-07 DE DE69315058T patent/DE69315058T2/de not_active Expired - Fee Related
- 1993-01-07 AP APAP/P/1993/000482A patent/AP381A/en active
- 1993-01-07 DK DK93902971.6T patent/DK0620833T3/da active
- 1993-01-07 CZ CZ941655A patent/CZ282312B6/cs unknown
- 1993-01-07 HU HU9402058A patent/HUT70831A/hu unknown
- 1993-01-07 AT AT93902971T patent/ATE159961T1/de not_active IP Right Cessation
- 1993-01-07 JP JP5512554A patent/JPH07509446A/ja not_active Ceased
- 1993-01-07 NZ NZ246791A patent/NZ246791A/en unknown
- 1993-01-08 ZA ZA93136A patent/ZA93136B/xx unknown
- 1993-01-08 MX MX9300081A patent/MX9300081A/es not_active IP Right Cessation
- 1993-01-08 IL IL10435493A patent/IL104354A/en not_active IP Right Cessation
- 1993-01-09 CN CN93100245A patent/CN1049670C/zh not_active Expired - Fee Related
- 1993-11-22 US US08/156,329 patent/US5512177A/en not_active Expired - Fee Related
-
1994
- 1994-07-08 FI FI943268A patent/FI108459B/fi active
- 1994-07-08 OA OA60535A patent/OA09962A/en unknown
- 1994-07-08 NO NO942574A patent/NO307610B1/no not_active IP Right Cessation
-
1997
- 1997-04-01 US US08/834,699 patent/US6013251A/en not_active Expired - Fee Related
- 1997-11-26 US US08/979,085 patent/US5986044A/en not_active Expired - Fee Related
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1998
- 1998-01-28 GR GR980400189T patent/GR3026019T3/el unknown
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