RU93005114A - Пенемовые соединения и фармацевтическая композиция на их основе - Google Patents
Пенемовые соединения и фармацевтическая композиция на их основеInfo
- Publication number
- RU93005114A RU93005114A RU93005114/04A RU93005114A RU93005114A RU 93005114 A RU93005114 A RU 93005114A RU 93005114/04 A RU93005114/04 A RU 93005114/04A RU 93005114 A RU93005114 A RU 93005114A RU 93005114 A RU93005114 A RU 93005114A
- Authority
- RU
- Russia
- Prior art keywords
- group
- basis
- pharmaceutical composition
- foam
- connections
- Prior art date
Links
- 239000006260 foam Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000003710 aryl alkyl group Chemical group 0.000 claims 2
- 230000003115 biocidal Effects 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 claims 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 claims 1
- 229940064005 Antibiotic throat preparations Drugs 0.000 claims 1
- 229940083879 Antibiotics FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE Drugs 0.000 claims 1
- 229940042052 Antibiotics for systemic use Drugs 0.000 claims 1
- 229940042786 Antitubercular Antibiotics Drugs 0.000 claims 1
- 229940093922 Gynecological Antibiotics Drugs 0.000 claims 1
- 229940024982 Topical Antifungal Antibiotics Drugs 0.000 claims 1
- 125000001931 aliphatic group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 229940079866 intestinal antibiotics Drugs 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229940005935 ophthalmologic Antibiotics Drugs 0.000 claims 1
- 125000004430 oxygen atoms Chemical group O* 0.000 claims 1
- 150000002961 penems Chemical class 0.000 claims 1
Claims (1)
- Соединения пенем, действующие как антибиотики, представлены следующей формулой:
где R представляет группу общей формулы:
или
CH2-Z,
в которой R1 является линейной или разветвленной C1 - C6 алкильной группой, R2 - необязательно замещенная или незамещенная алкильная, арильная или аралкильная группа, n - целое число от 1 до 6, Y - 5- или 6-членная гетероциклическая алифатическая группа с 1 или 2 атомами кислорода в ее кольце, а Z -необязательно 5-замещенная 2-оксо-1,3-диоксоленил-4 группа. Предложены также композиции на основе антибиотиков для перорального применения.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21705290 | 1990-08-20 | ||
| JP2-217052 | 1990-08-20 | ||
| PCT/JP1991/001098 WO1992003442A1 (en) | 1990-08-20 | 1991-08-16 | Antibacterial penem esters derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93005114A true RU93005114A (ru) | 1995-10-27 |
| RU2051919C1 RU2051919C1 (ru) | 1996-01-10 |
Family
ID=16698076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU93005114/04A RU2051919C1 (ru) | 1990-08-20 | 1991-08-16 | Соединения пенема и фармацевтическая композиция на их основе |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US5830889A (ru) |
| EP (2) | EP0757050B1 (ru) |
| JP (2) | JP3148234B2 (ru) |
| KR (1) | KR0178956B1 (ru) |
| AT (2) | ATE186053T1 (ru) |
| AU (1) | AU652954B2 (ru) |
| BR (1) | BR9106789A (ru) |
| CA (1) | CA2089368C (ru) |
| CZ (1) | CZ282086B6 (ru) |
| DE (2) | DE69133273T2 (ru) |
| DK (1) | DK0544907T3 (ru) |
| ES (2) | ES2198455T3 (ru) |
| FI (1) | FI105186B (ru) |
| GR (1) | GR3032372T3 (ru) |
| HU (1) | HU213403B (ru) |
| IE (1) | IE20000929A1 (ru) |
| IL (1) | IL99243A (ru) |
| MX (1) | MX9203822A (ru) |
| NO (1) | NO302236B1 (ru) |
| PL (1) | PL169584B1 (ru) |
| RU (1) | RU2051919C1 (ru) |
| SK (1) | SK280188B6 (ru) |
| WO (1) | WO1992003442A1 (ru) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999036098A1 (fr) * | 1998-01-13 | 1999-07-22 | Suntory Limited | Composition antibacterienne contenant des antibiotiques et destinee a l'administration topique |
| EP1191948A2 (en) * | 1999-06-11 | 2002-04-03 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
| US7094885B2 (en) | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| JP2004536034A (ja) | 2001-01-08 | 2004-12-02 | ネオルクス コーポレイション | 治療的および診断的化合物、組成物および方法 |
| WO2003051403A1 (en) | 2001-12-13 | 2003-06-26 | Dow Global Technologies Inc. | Treatment of osteomyelitis with radiopharmaceuticals |
| WO2004031196A1 (ja) * | 2002-10-02 | 2004-04-15 | Nippon Soda Co., Ltd. | 有機化合物の製造方法 |
| CN1314691C (zh) * | 2005-08-22 | 2007-05-09 | 鲁南制药集团股份有限公司 | 法罗培南钠的制备方法 |
| WO2007039885A1 (en) * | 2005-10-05 | 2007-04-12 | Ranbaxy Laboratories Limited | A process for the preparation of faropenem |
| US20080125408A1 (en) * | 2006-11-14 | 2008-05-29 | Pfizer Inc | Penem prodrug |
| CN101235044B (zh) * | 2008-03-03 | 2010-11-03 | 南京华威医药科技开发有限公司 | 法罗培南酯的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6019908B2 (ja) * | 1980-04-30 | 1985-05-18 | カネボウ株式会社 | １，３−ジオキソレン−２−オン誘導体 |
| CA1212105A (en) * | 1980-04-30 | 1986-09-30 | Shoji Ikeda | Ampicillin esters and production thereof |
| US4654331A (en) * | 1981-07-13 | 1987-03-31 | Merck & Co., Inc. | Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group |
| US4479947A (en) * | 1981-07-13 | 1984-10-30 | Merck & Co., Inc. | Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group |
| JPS58159496A (ja) * | 1983-03-02 | 1983-09-21 | Kyoto Yakuhin Kogyo Kk | セフエム系化合物 |
| JPH075463B2 (ja) * | 1985-03-09 | 1995-01-25 | サントリー株式会社 | 抗菌剤 |
| EP0275002A1 (en) * | 1987-01-09 | 1988-07-20 | Hoechst Aktiengesellschaft | Process for the production of 7-oxo-4-thia-1-aza-bicyclo [3.2.0] hept-2-ene derivatives |
| GB8713515D0 (en) * | 1987-06-10 | 1987-07-15 | Erba Farmitalia | Methoxymethyl compounds |
| GB2206578B (en) * | 1987-07-07 | 1991-07-03 | Erba Carlo Spa | Process for the preparation of penems |
| JPH026728A (ja) | 1988-06-23 | 1990-01-10 | Japan Radio Co Ltd | 弾性表面波による液体粘性測定装置 |
| GB2220203B (en) * | 1988-07-04 | 1991-09-11 | Erba Carlo Spa | Process for penems |
| DE3839987A1 (de) * | 1988-11-26 | 1990-05-31 | Hoechst Ag | Penemderivate und verfahren zu ihrer herstellung |
| EP0399228A1 (de) * | 1989-04-29 | 1990-11-28 | Hoechst Aktiengesellschaft | Verfahren zur Herstellung von Penemverbindungen |
-
1991
- 1991-08-16 SK SK107-93A patent/SK280188B6/sk unknown
- 1991-08-16 IE IE20000929A patent/IE20000929A1/en unknown
- 1991-08-16 ES ES96117054T patent/ES2198455T3/es not_active Expired - Lifetime
- 1991-08-16 DE DE69133273T patent/DE69133273T2/de not_active Expired - Lifetime
- 1991-08-16 DE DE69131753T patent/DE69131753T2/de not_active Expired - Lifetime
- 1991-08-16 ES ES91914618T patent/ES2137929T3/es not_active Expired - Lifetime
- 1991-08-16 EP EP96117054A patent/EP0757050B1/en not_active Expired - Lifetime
- 1991-08-16 EP EP91914618A patent/EP0544907B1/en not_active Expired - Lifetime
- 1991-08-16 US US07/971,829 patent/US5830889A/en not_active Expired - Fee Related
- 1991-08-16 BR BR919106789A patent/BR9106789A/pt not_active Application Discontinuation
- 1991-08-16 CA CA002089368A patent/CA2089368C/en not_active Expired - Lifetime
- 1991-08-16 JP JP51345591A patent/JP3148234B2/ja not_active Expired - Fee Related
- 1991-08-16 MX MX9203822A patent/MX9203822A/es unknown
- 1991-08-16 RU RU93005114/04A patent/RU2051919C1/ru not_active IP Right Cessation
- 1991-08-16 AU AU83333/91A patent/AU652954B2/en not_active Ceased
- 1991-08-16 KR KR1019930700426A patent/KR0178956B1/ko not_active IP Right Cessation
- 1991-08-16 AT AT91914618T patent/ATE186053T1/de not_active IP Right Cessation
- 1991-08-16 AT AT96117054T patent/ATE242251T1/de not_active IP Right Cessation
- 1991-08-16 HU HU9300461A patent/HU213403B/hu unknown
- 1991-08-16 DK DK91914618T patent/DK0544907T3/da active
- 1991-08-16 CZ CZ93209A patent/CZ282086B6/cs not_active IP Right Cessation
- 1991-08-16 WO PCT/JP1991/001098 patent/WO1992003442A1/en active IP Right Grant
- 1991-08-16 PL PL91297971A patent/PL169584B1/pl not_active IP Right Cessation
- 1991-08-20 IL IL9924391A patent/IL99243A/en not_active IP Right Cessation
-
1993
- 1993-02-16 FI FI930682A patent/FI105186B/fi active
- 1993-02-19 NO NO930588A patent/NO302236B1/no not_active IP Right Cessation
-
1995
- 1995-06-06 US US08/470,944 patent/US5885981A/en not_active Expired - Fee Related
-
2000
- 2000-01-14 GR GR20000400071T patent/GR3032372T3/el not_active IP Right Cessation
- 2000-04-10 JP JP2000108222A patent/JP3274854B2/ja not_active Expired - Fee Related
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