GR3032372T3 - Antibacterial penem esters derivatives. - Google Patents

Antibacterial penem esters derivatives.

Info

Publication number
GR3032372T3
GR3032372T3 GR20000400071T GR20000400071T GR3032372T3 GR 3032372 T3 GR3032372 T3 GR 3032372T3 GR 20000400071 T GR20000400071 T GR 20000400071T GR 20000400071 T GR20000400071 T GR 20000400071T GR 3032372 T3 GR3032372 T3 GR 3032372T3
Authority
GR
Greece
Prior art keywords
group
penem
esters derivatives
tetrahydrofurylü
hydroxyethylü
Prior art date
Application number
GR20000400071T
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GR3032372T3 publication Critical patent/GR3032372T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/861—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hydrocarbon radical or a substituted hydrocarbon radical, directly attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/893—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with a hetero ring or a condensed hetero ring system, directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Saccharide Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR20000400071T 1990-08-20 2000-01-14 Antibacterial penem esters derivatives. GR3032372T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21705290 1990-08-20
PCT/JP1991/001098 WO1992003442A1 (en) 1990-08-20 1991-08-16 Antibacterial penem esters derivatives

Publications (1)

Publication Number Publication Date
GR3032372T3 true GR3032372T3 (en) 2000-04-27

Family

ID=16698076

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000400071T GR3032372T3 (en) 1990-08-20 2000-01-14 Antibacterial penem esters derivatives.

Country Status (23)

Country Link
US (2) US5830889A (el)
EP (2) EP0757050B1 (el)
JP (2) JP3148234B2 (el)
KR (1) KR0178956B1 (el)
AT (2) ATE242251T1 (el)
AU (1) AU652954B2 (el)
BR (1) BR9106789A (el)
CA (1) CA2089368C (el)
CZ (1) CZ282086B6 (el)
DE (2) DE69131753T2 (el)
DK (1) DK0544907T3 (el)
ES (2) ES2137929T3 (el)
FI (1) FI105186B (el)
GR (1) GR3032372T3 (el)
HU (1) HU213403B (el)
IE (1) IE20000929A1 (el)
IL (1) IL99243A (el)
MX (1) MX9203822A (el)
NO (1) NO302236B1 (el)
PL (1) PL169584B1 (el)
RU (1) RU2051919C1 (el)
SK (1) SK280188B6 (el)
WO (1) WO1992003442A1 (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE283707T1 (de) * 1998-01-13 2004-12-15 Daiichi Suntory Pharma Co Ltd Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem
EP1191948A2 (en) * 1999-06-11 2002-04-03 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
JP2004536034A (ja) * 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
JP2005516933A (ja) 2001-12-13 2005-06-09 ダウ グローバル テクノロジーズ インコーポレイティド 放射性医薬による骨髄炎の治療
CA2500330C (en) * 2002-10-02 2008-08-12 Nippon Soda Co., Ltd. Processes for preparation of organic compounds
CN1314691C (zh) * 2005-08-22 2007-05-09 鲁南制药集团股份有限公司 法罗培南钠的制备方法
US7977475B2 (en) * 2005-10-05 2011-07-12 Ranbaxy Laboratories Limited Process for the preparation of faropenem
US20080125408A1 (en) * 2006-11-14 2008-05-29 Pfizer Inc Penem prodrug
CN101235044B (zh) * 2008-03-03 2010-11-03 南京华威医药科技开发有限公司 法罗培南酯的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019908B2 (ja) * 1980-04-30 1985-05-18 カネボウ株式会社 １，３−ジオキソレン−２−オン誘導体
CA1212105A (en) * 1980-04-30 1986-09-30 Shoji Ikeda Ampicillin esters and production thereof
US4479947A (en) * 1981-07-13 1984-10-30 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
US4654331A (en) * 1981-07-13 1987-03-31 Merck & Co., Inc. Oral absorption enhancement of carboxylic acid pharmaceuticals using (5-alkyl-2-oxo-1,3-dioxolen-4-yl)methyl ester group
JPS58159496A (ja) * 1983-03-02 1983-09-21 Kyoto Yakuhin Kogyo Kk セフエム系化合物
JPH075463B2 (ja) * 1985-03-09 1995-01-25 サントリー株式会社 抗菌剤
EP0275002A1 (en) * 1987-01-09 1988-07-20 Hoechst Aktiengesellschaft Process for the production of 7-oxo-4-thia-1-aza-bicyclo [3.2.0] hept-2-ene derivatives
GB8713515D0 (en) * 1987-06-10 1987-07-15 Erba Farmitalia Methoxymethyl compounds
GB2206578B (en) * 1987-07-07 1991-07-03 Erba Carlo Spa Process for the preparation of penems
JPH026728A (ja) 1988-06-23 1990-01-10 Japan Radio Co Ltd 弾性表面波による液体粘性測定装置
GB2220203B (en) * 1988-07-04 1991-09-11 Erba Carlo Spa Process for penems
DE3839987A1 (de) * 1988-11-26 1990-05-31 Hoechst Ag Penemderivate und verfahren zu ihrer herstellung
EP0399228A1 (de) * 1989-04-29 1990-11-28 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Penemverbindungen

Also Published As

Publication number Publication date
ES2198455T3 (es) 2004-02-01
CA2089368C (en) 2002-08-06
DE69131753D1 (de) 1999-12-02
IE20000929A1 (en) 2001-05-30
NO930588D0 (no) 1993-02-19
DE69133273T2 (de) 2004-05-13
JP3148234B2 (ja) 2001-03-19
HUT64349A (en) 1993-12-28
KR0178956B1 (ko) 1999-03-20
AU652954B2 (en) 1994-09-15
CA2089368A1 (en) 1992-02-21
US5830889A (en) 1998-11-03
DK0544907T3 (da) 2000-01-24
MX9203822A (es) 1992-09-01
NO930588L (no) 1993-02-19
CZ20993A3 (en) 1993-10-13
JP3274854B2 (ja) 2002-04-15
SK10793A3 (en) 1993-09-09
ES2137929T3 (es) 2000-01-01
DE69133273D1 (de) 2003-07-10
KR930701452A (ko) 1993-06-11
EP0757050A1 (en) 1997-02-05
FI930682A (fi) 1993-02-16
ATE242251T1 (de) 2003-06-15
EP0544907B1 (en) 1999-10-27
US5885981A (en) 1999-03-23
IL99243A0 (en) 1992-07-15
SK280188B6 (sk) 1999-09-10
IL99243A (en) 1995-07-31
EP0757050B1 (en) 2003-06-04
FI105186B (fi) 2000-06-30
JPH06500769A (ja) 1994-01-27
HU213403B (en) 1997-06-30
FI930682A0 (fi) 1993-02-16
RU2051919C1 (ru) 1996-01-10
NO302236B1 (no) 1998-02-09
DE69131753T2 (de) 2000-05-04
BR9106789A (pt) 1993-06-29
ATE186053T1 (de) 1999-11-15
PL169584B1 (pl) 1996-08-30
EP0544907A1 (en) 1993-06-09
WO1992003442A1 (en) 1992-03-05
AU8333391A (en) 1992-03-17
JP2000302786A (ja) 2000-10-31
CZ282086B6 (cs) 1997-05-14
HU9300461D0 (en) 1993-05-28

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Legal Events

Date Code Title Description
ML Lapse due to non-payment of fees

Effective date: 20110302