RU2745601C2 - Составы, содержащие антитела - Google Patents

Составы, содержащие антитела Download PDF

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Publication number
RU2745601C2
RU2745601C2 RU2015132431A RU2015132431A RU2745601C2 RU 2745601 C2 RU2745601 C2 RU 2745601C2 RU 2015132431 A RU2015132431 A RU 2015132431A RU 2015132431 A RU2015132431 A RU 2015132431A RU 2745601 C2 RU2745601 C2 RU 2745601C2
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RU
Russia
Prior art keywords
composition
formulation
present
acz885
antibodies
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RU2015132431A
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English (en)
Russian (ru)
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RU2015132431A (ru
RU2015132431A3 (OSRAM
Inventor
Йоахим МОММ
Ханс-Йоахим ВАЛЛЬНИ
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Новартис Аг
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40637230&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2745601(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Новартис Аг filed Critical Новартис Аг
Publication of RU2015132431A publication Critical patent/RU2015132431A/ru
Publication of RU2015132431A3 publication Critical patent/RU2015132431A3/ru
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/245IL-1

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
RU2015132431A 2008-12-10 2009-12-09 Составы, содержащие антитела RU2745601C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08170884.4 2008-12-10
EP08170884A EP2196476A1 (en) 2008-12-10 2008-12-10 Antibody formulation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU2011127913/15A Division RU2563179C2 (ru) 2008-12-10 2009-12-09 Составы, содержащие антитела

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2021107534A Division RU2021107534A (ru) 2008-12-10 2021-03-23 Составы, содержащие антитела

Publications (3)

Publication Number Publication Date
RU2015132431A RU2015132431A (ru) 2018-12-24
RU2015132431A3 RU2015132431A3 (OSRAM) 2018-12-24
RU2745601C2 true RU2745601C2 (ru) 2021-03-29

Family

ID=40637230

Family Applications (2)

Application Number Title Priority Date Filing Date
RU2015132431A RU2745601C2 (ru) 2008-12-10 2009-12-09 Составы, содержащие антитела
RU2011127913/15A RU2563179C2 (ru) 2008-12-10 2009-12-09 Составы, содержащие антитела

Family Applications After (1)

Application Number Title Priority Date Filing Date
RU2011127913/15A RU2563179C2 (ru) 2008-12-10 2009-12-09 Составы, содержащие антитела

Country Status (31)

Country Link
US (3) US20110236398A1 (OSRAM)
EP (4) EP2196476A1 (OSRAM)
JP (5) JP6143416B2 (OSRAM)
KR (2) KR20170044211A (OSRAM)
CN (3) CN102245639B (OSRAM)
AU (1) AU2009324371B2 (OSRAM)
BR (1) BRPI0922730A2 (OSRAM)
CA (1) CA2745938C (OSRAM)
CL (1) CL2011001406A1 (OSRAM)
CO (1) CO6361952A2 (OSRAM)
CY (2) CY1117735T1 (OSRAM)
DK (2) DK2376533T3 (OSRAM)
EC (1) ECSP11011192A (OSRAM)
ES (2) ES2579835T3 (OSRAM)
HR (2) HRP20160754T1 (OSRAM)
HU (2) HUE028408T2 (OSRAM)
IL (3) IL264316B2 (OSRAM)
LT (1) LT3072906T (OSRAM)
MA (1) MA33023B1 (OSRAM)
MX (1) MX2011006242A (OSRAM)
MY (2) MY166050A (OSRAM)
NZ (1) NZ592918A (OSRAM)
PE (1) PE20120342A1 (OSRAM)
PL (2) PL3072906T3 (OSRAM)
PT (2) PT3072906T (OSRAM)
RU (2) RU2745601C2 (OSRAM)
SI (2) SI2376533T1 (OSRAM)
SM (1) SMT201600222B (OSRAM)
TN (1) TN2011000229A1 (OSRAM)
WO (1) WO2010066762A1 (OSRAM)
ZA (1) ZA201103362B (OSRAM)

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EA201892184A1 (ru) 2010-03-01 2019-03-29 БАЙЕР ХЕЛЬСКЕР ЛЛСи Оптимизированные моноклональные антитела против ингибитора пути тканевого фактора
US20130136733A1 (en) 2010-05-28 2013-05-30 Novo Nordisk A/S Stable Multi-Dose Compositions Comprising an Antibody and a Preservative
AR082319A1 (es) * 2010-07-22 2012-11-28 Biomarin Pharm Inc Produccion de una n-acetilgalactosamina-6-sulfatasa humana activa altamente fosforilada y sus usos
US8822663B2 (en) 2010-08-06 2014-09-02 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
TWI621625B (zh) 2010-09-17 2018-04-21 巴克斯歐塔公司 在弱酸性至中性ph中經由具有組胺酸的水性調配物穩定免疫球蛋白
CA2821992A1 (en) 2010-10-01 2012-04-05 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
TWI700093B (zh) 2011-03-16 2020-08-01 法商賽諾菲公司 雙重v區類抗體蛋白質之用途
DE12722942T1 (de) 2011-03-31 2021-09-30 Modernatx, Inc. Freisetzung und formulierung von manipulierten nukleinsäuren
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
HRP20220250T1 (hr) 2011-10-03 2022-04-29 Modernatx, Inc. Modificirani nukleozidi, nukleotidi i nukleinske kiseline, te njihove uporabe
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DK3072906T3 (da) 2021-12-13
JP7286595B2 (ja) 2023-06-05
RU2015132431A (ru) 2018-12-24
TN2011000229A1 (en) 2012-12-17
HRP20160754T1 (hr) 2016-08-12
PE20120342A1 (es) 2012-04-24
US8623367B2 (en) 2014-01-07
KR20170044211A (ko) 2017-04-24
CL2011001406A1 (es) 2012-03-30
ECSP11011192A (es) 2011-08-31
MA33023B1 (fr) 2012-02-01
WO2010066762A1 (en) 2010-06-17
JP2015231997A (ja) 2015-12-24
PT2376533T (pt) 2016-07-13
EP3792282A1 (en) 2021-03-17
HUE028408T2 (en) 2016-12-28
IL264316B2 (en) 2024-01-01
KR101762966B1 (ko) 2017-07-31
CN102245639A (zh) 2011-11-16
US20120315285A1 (en) 2012-12-13
CY1124844T1 (el) 2022-11-25
LT3072906T (lt) 2021-12-27
JP2023109938A (ja) 2023-08-08
ES2579835T3 (es) 2016-08-17
RU2011127913A (ru) 2013-01-20
KR20120009421A (ko) 2012-01-31
BRPI0922730A2 (pt) 2018-11-06
PL3072906T3 (pl) 2022-01-24
EP3072906B1 (en) 2021-09-08
AU2009324371A1 (en) 2011-06-23
US20110236398A1 (en) 2011-09-29
MY157772A (en) 2016-07-29
NZ592918A (en) 2012-12-21
HK1159130A1 (zh) 2012-07-27
ZA201103362B (en) 2012-01-25
US20200384108A1 (en) 2020-12-10
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