RU2745506C2 - Кодирующие фактор viii варианты с пониженным содержанием cpg, композиции и способы и применение в лечении нарушений гемостаза - Google Patents
Кодирующие фактор viii варианты с пониженным содержанием cpg, композиции и способы и применение в лечении нарушений гемостаза Download PDFInfo
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Applications Claiming Priority (9)
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| US201562249001P | 2015-10-30 | 2015-10-30 | |
| US62/249,001 | 2015-10-30 | ||
| US201662331872P | 2016-05-04 | 2016-05-04 | |
| US62/331,872 | 2016-05-04 | ||
| US201662349532P | 2016-06-13 | 2016-06-13 | |
| US62/349,532 | 2016-06-13 | ||
| US201662357874P | 2016-07-01 | 2016-07-01 | |
| US62/357,874 | 2016-07-01 | ||
| PCT/US2016/059793 WO2017075619A1 (en) | 2015-10-30 | 2016-10-31 | Cpg reduced factor viii variants, compositions and methods and uses for treatment of hemostasis disorders |
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| RU2018119710A RU2018119710A (ru) | 2019-12-06 |
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| JP (3) | JP7088831B2 (https=) |
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| CN (1) | CN108368164A (https=) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2808564C2 (ru) * | 2022-04-28 | 2023-11-29 | Акционерное общество "БИОКАД" | Кодон-оптимизированная нуклеиновая кислота, которая кодирует белок фактора свёртывания крови VIII c делетированным B доменом, и ее применение |
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| GB201508026D0 (en) | 2015-05-11 | 2015-06-24 | Ucl Business Plc | Capsid |
| MX390848B (es) | 2015-06-23 | 2025-03-21 | Childrens Hospital Philadelphia | Factor ix modificado, y composiciones, metodos y usos para la transferencia de genes a celulas, organos y tejidos. |
| PE20231949A1 (es) * | 2015-10-30 | 2023-12-05 | Spark Therapeutics Inc | VARIANTES DEL FACTOR VIII REDUCIDO CON CpG, COMPOSICIONES Y METODOS Y USOS PARA EL TRATAMIENTO DE TRASTORNOS DE LA HEMOSTASIA |
| IL305149A (en) | 2016-07-26 | 2023-10-01 | Biomarin Pharm Inc | Novel adeno-associated virus capsid proteins |
| PE20200722A1 (es) * | 2017-08-01 | 2020-07-21 | Spark Therapeutics Inc | Metodos de terapia genica del factor viii (fviii) |
| NZ762100A (en) | 2017-08-09 | 2025-12-19 | Bioverativ Therapeutics Inc | Nucleic acid molecules and uses thereof |
| KR101952102B1 (ko) * | 2017-12-07 | 2019-02-26 | 주식회사 지앤피바이오사이언스 | 단백질 발현량이 증대된 인자 ⅷ 변이체 발현벡터 |
| TW202016314A (zh) | 2018-05-09 | 2020-05-01 | 美商拜奧馬林製藥公司 | 治療苯丙酮尿症之方法 |
| TW202016298A (zh) | 2018-05-14 | 2020-05-01 | 美商拜奧馬林製藥公司 | Aav 載體於幼年受試者中之穩定表現 |
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